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M. leprae Br4923 MLBr_01810 (moxR)

annotation: MoxR homolog
coordinates: 2190405 - 2191538
length: 377

TSAGGLPVGADGCSGPGGQSGPRAHEAPPGGADGLVAEVHTLERAIFEVKRVIVGQDQLVERMLVGLLSK
GHVLLEGVPGVAKTLAVETFARVVGGTFARIQFTPDLVPTDIIGTRIYRQGKEEFDTELGPVVVNFLLAD
EINRAPAKVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYLLPEAQRDRFLFKINVGYPS
PEEEREIIYRMGVTPPVPKQILNAGDLLRLQEISANNFVHHALVDYVVRVVTATRHPEQLGMNDVKTWIS
FGASPRASLGIIKASRSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYNALADEISPEIVINRVLQTVAL
PQVNSFPQQGHSVPSVTQAAAAASGR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01810moxR-100% (377)MoxR homolog

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1515moxR10.090.19% (377) transcriptional regulatory protein MOXR1
M. gilvum PYR-GCKMflv_3661-1e-17281.09% (386) ATPase
M. tuberculosis H37RvRv1479moxR10.090.19% (377) transcriptional regulatory protein MOXR1
M. abscessus ATCC 19977MAB_2726c-1e-15877.69% (363) hypothetical protein MAB_2726c
M. marinum MMMAR_2286moxR10.089.12% (377) transcriptional regulatory protein, MoxR1
M. avium 104MAV_3299-0.090.79% (380) MoxR protein
M. smegmatis MC2 155MSMEG_3147moxR1e-16885.47% (344) ATPase, MoxR family protein
M. thermoresistible (build 8)TH_3229-1e-16979.63% (383) PUTATIVE ATPase associated with various cellular activities,
M. ulcerans Agy99MUL_1488moxR10.089.12% (377) transcriptional regulatory protein, MoxR1
M. vanbaalenii PYR-1Mvan_2749-1e-17381.30% (385) ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3661|M.gilvum_PYR-GCK          -----MTSPSGPPQGAGGYPGQGPAQGYSAGAHAAGNSAPGSAQTNGGLQ
Mvan_2749|M.vanbaalenii_PYR-1       -----MTSPSGPPQGAGGYPGQVPAQGYSSGAHAAP-SQPGPPQSNGGLQ
MSMEG_3147|M.smegmatis_MC2_155      -------------------------------------------MNNGGLQ
TH_3229|M.thermoresistible__bu      VEELRMTSPSGPQQGSGGYSGSAPAPGYPAGSHAAPPTNGG----QSGLQ
MLBr_01810|M.leprae_Br4923          -----MTSAGGLPVGADGCSGPGGQS--GPRAHEAPPGGA------DGLV
MAV_3299|M.avium_104                -----MTAAGGPPPGAGGYSGPGGQS--GPGAHEAPTGGAG---AGNGLA
Mb1515|M.bovis_AF2122/97            -----MTSAGGFPAGAGGYQTPGGHS--ASPAHEAPPGGA------EGLA
Rv1479|M.tuberculosis_H37Rv         -----MTSAGGFPAGAGGYQTPGGHS--ASPAHEAPPGGA------EGLA
MMAR_2286|M.marinum_M               -----MTSAGG------GYSGPGGHS--APPAHEAPSGGP------DGLA
MUL_1488|M.ulcerans_Agy99           -----MTSAGG------GYSGPGGHS--APPAHEAPSGGP------DGLA
MAB_2726c|M.abscessus_ATCC_199      ------MSSPGQPGGGAGYTGGSAGS-----APHAPQGATS-----PALA
                                                                                   .* 

Mflv_3661|M.gilvum_PYR-GCK          NEVHTLERAIFEVKRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLA
Mvan_2749|M.vanbaalenii_PYR-1       NEVHTLERAIFEVKRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLA
MSMEG_3147|M.smegmatis_MC2_155      AEVHTLERAIFEVKRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLA
TH_3229|M.thermoresistible__bu      ADVHTLERTIFEVKRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLA
MLBr_01810|M.leprae_Br4923          AEVHTLERAIFEVKRVIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLA
MAV_3299|M.avium_104                AEVQTLERAIFEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLA
Mb1515|M.bovis_AF2122/97            AEVHTLERAIFEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLA
Rv1479|M.tuberculosis_H37Rv         AEVHTLERAIFEVKRIIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLA
MMAR_2286|M.marinum_M               AEVHTLERAIFEVKRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLA
MUL_1488|M.ulcerans_Agy99           AEVHTLERAIFEVKRIIVGQDQLVERMLVGLLAKGHVLLEGVPGVAKTLA
MAB_2726c|M.abscessus_ATCC_199      AEVQNLERAIFEVKRIIVGQDRLVERILVGLLAKGHVLLEGVPGVAKTLA
                                     :*:.***:******:*****:****:*****:*****************

Mflv_3661|M.gilvum_PYR-GCK          VETFAKVVGGTFARIQFTPDLVPTDIVGTRIYRQGKEEFDIELGPVVVNF
Mvan_2749|M.vanbaalenii_PYR-1       VETFAKVVGGTFARIQFTPDLVPTDIIGTRIYRQGKEEFDIELGPVVVNF
MSMEG_3147|M.smegmatis_MC2_155      VETFAKVVGGTFARIQFTPDLVPTDIVGTRIYRQGKEEFEIELGPAVVNF
TH_3229|M.thermoresistible__bu      VETFARVVGGTFARIQFTPDLVPTDIVGTRIYRQGKEEFDIELGPVMVNF
MLBr_01810|M.leprae_Br4923          VETFARVVGGTFARIQFTPDLVPTDIIGTRIYRQGKEEFDTELGPVVVNF
MAV_3299|M.avium_104                VETFAKVVGGTFARIQFTPDLVPTDIIGTRIYRQGKEEFDTELGPVVVNF
Mb1515|M.bovis_AF2122/97            VETFARVVGGTFSRIQFTPDLVPTDIIGTRIYRQGREEFDTELGPVVANF
Rv1479|M.tuberculosis_H37Rv         VETFARVVGGTFSRIQFTPDLVPTDIIGTRIYRQGREEFDTELGPVVANF
MMAR_2286|M.marinum_M               VETFARVVGGSFARIQFTPDLVPTDIVGTRIYRQGKEEFDTELGPVVANF
MUL_1488|M.ulcerans_Agy99           VETFARVVGGSFARIQFTPDLVPTDIVGTRIYRQGKEEFDTELGPVVANF
MAB_2726c|M.abscessus_ATCC_199      VETFAKVVGGTFSRIQFTPDLVPTDIIGTRIYRQGREEFDTELGPVVANF
                                    *****:****:*:*************:********:***: ****.:.**

Mflv_3661|M.gilvum_PYR-GCK          LLADEINRAPAKVQSALLEIMAERKISIGGKTFPLPSPFLVMATQNPIEQ
Mvan_2749|M.vanbaalenii_PYR-1       LLADEINRAPAKVQSALLEVMAERKISIGGKTFPLPSPFLVMATQNPIEQ
MSMEG_3147|M.smegmatis_MC2_155      LLADEINRAPAKVQSALLEIMAERKISIGGQTFPLPSPFLVMATQNPIEQ
TH_3229|M.thermoresistible__bu      LLADEINRAPAKVQSALLEVMAERKISIGGKTFLLPKPFLVMATQNPIEQ
MLBr_01810|M.leprae_Br4923          LLADEINRAPAKVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEH
MAV_3299|M.avium_104                LLADEINRAPAKVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEH
Mb1515|M.bovis_AF2122/97            LLADEINRAPAKVQSALLEVMQERHVSIGGRTFPMPSPFLVMATQNPIEH
Rv1479|M.tuberculosis_H37Rv         LLADEINRAPAKVQSALLEVMQERHVSIGGRTFPMPSPFLVMATQNPIEH
MMAR_2286|M.marinum_M               LLADEINRAPAKVQSALLEVMAERHVSIGGKTFPMPNPFLVMATQNPIEQ
MUL_1488|M.ulcerans_Agy99           LLADEINRAPAKVQSALLEVMAERHVSIGGKTFPMPNPFLVMATQNPIEQ
MAB_2726c|M.abscessus_ATCC_199      LLADEINRAPAKVQSALLEVMAERKISIGGKDYHLPKPFLVMATQNPIEN
                                    *******************:* **::****: : :*.************:

Mflv_3661|M.gilvum_PYR-GCK          EGVYQLPEAQRDRFLFKLNVDYPSPEEEREIIYRMGVKPPEPKGILTTAD
Mvan_2749|M.vanbaalenii_PYR-1       EGVYQLPEAQRDRFLFKLNVDYPTPEEEREIIYRMGVKPPEPKAILNTGD
MSMEG_3147|M.smegmatis_MC2_155      EGVYQLPEAQRDRFLFKLNVDYPSPEEEREIIYRMGVKPPEPKQILTTGD
TH_3229|M.thermoresistible__bu      EGVYALPEAQRDRFLFKLNIDYPSPEEEREIIYRMGVKPPEPKQVLAPGD
MLBr_01810|M.leprae_Br4923          EGVYLLPEAQRDRFLFKINVGYPSPEEEREIIYRMGVTPPVPKQILNAGD
MAV_3299|M.avium_104                EGVYPLPEAQRDRFLFKINVGYPSPEEEREIIYRMGVRPPEPKQILNTGD
Mb1515|M.bovis_AF2122/97            EGVYPLPEAQRDRFLFKINVGYPSPEEEREIIYRMGVTPPQAKQILSTGD
Rv1479|M.tuberculosis_H37Rv         EGVYPLPEAQRDRFLFKINVGYPSPEEEREIIYRMGVTPPQAKQILSTGD
MMAR_2286|M.marinum_M               EGVYPLPEAQRDRFLFKINVGYPTPEEEREIIYRMGVTPPQPKQILGTGD
MUL_1488|M.ulcerans_Agy99           EGVYPLPEAQRDRFLFKINVGYPTPEEEREIIYRMGVTPPQPKQILGTGD
MAB_2726c|M.abscessus_ATCC_199      EGVYPLPEAQRDRFLFKINVDYPTVEEEREIIYRMGVTPPEPKQILSSEA
                                    **** ************:*:.**: ************ ** .* :* .  

Mflv_3661|M.gilvum_PYR-GCK          LLRLQDVAANNFVHHALVDYVVRIVTATREPEKFGMPDAKAWIAYGASPR
Mvan_2749|M.vanbaalenii_PYR-1       LLRLQDVAANNFVHHALVDYVVRIVTATREPEKFGMPDAKAWIAYGASPR
MSMEG_3147|M.smegmatis_MC2_155      LLRLQDVAANTFVHHALVDYVVRIVTATREPEKFGMPDAKAWIAYGASPR
TH_3229|M.thermoresistible__bu      LLRLQEVAANNFVHHALVDYVVRVVTATREPEKFGMPDAKAWIAYGASPR
MLBr_01810|M.leprae_Br4923          LLRLQEISANNFVHHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPR
MAV_3299|M.avium_104                LVRLQDIAANVFVHHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPR
Mb1515|M.bovis_AF2122/97            LLRLQEIAANNFVHHALVDYVVRVVFATRKPEQLGMNDVKSWVAFGASPR
Rv1479|M.tuberculosis_H37Rv         LLRLQEIAANNFVHHALVDYVVRVVFATRKPEQLGMNDVKSWVAFGASPR
MMAR_2286|M.marinum_M               LLRLQDIAANNFVHHALVDYVVRVVMATRQPEQLGMNDVKTWIAFGASPR
MUL_1488|M.ulcerans_Agy99           LLRLQDIAANNFVHHALVDYVVRVVMATRQPEQLGMNDVKTWIAFGASPR
MAB_2726c|M.abscessus_ATCC_199      LLRLQDLAANNFVHHALVDYVVRVIAATRNPAQFGLGDVANWISYGASPR
                                    *:***:::** ************:: ***.* ::*: *.  *:::*****

Mflv_3661|M.gilvum_PYR-GCK          ASLGIIAASRALALVRGRDYVIPQDVVEVIPDVLRHRLVLTYDALADEIS
Mvan_2749|M.vanbaalenii_PYR-1       ASLGIIAASRALALVRGRDYVIPQDVVEIIPDVLRHRLVLTYDALADEIS
MSMEG_3147|M.smegmatis_MC2_155      ASLGIISAARALALVRGRDYVIPQDVVEVIPDVLRHRLVLTYDALADEIS
TH_3229|M.thermoresistible__bu      ASLGIIAAARALALVRGRDYVIPQDVVEVIPDVLRHRLVLTYDALADEVT
MLBr_01810|M.leprae_Br4923          ASLGIIKASRSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYNALADEIS
MAV_3299|M.avium_104                ASLGIIAGARSLALVRGRDYVIPQDVVDVIPDVLRHRLVLTYDALADEIS
Mb1515|M.bovis_AF2122/97            ASLGIIAAARSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYDALADEIS
Rv1479|M.tuberculosis_H37Rv         ASLGIIAAARSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYDALADEIS
MMAR_2286|M.marinum_M               ASLGIIAASRALALVRGRDYVIPQDIIEVVPDVLRHRLVLTYDALADEIS
MUL_1488|M.ulcerans_Agy99           ASLGIIAASRALALVRGRDYVIPQDIIEVVPDVLRHRLVLTYDALADEIS
MAB_2726c|M.abscessus_ATCC_199      ASLGIIASARALALVRGRDYVIPQDVIEVIPDVLRHRLVMSYDALADEVS
                                    ****** .:*:**************:::::*********::*:*****::

Mflv_3661|M.gilvum_PYR-GCK          AETVVNRILQTVALPQVNAIPQQGHSVPPV------VPAAAAAASGR
Mvan_2749|M.vanbaalenii_PYR-1       SETVVNRILQTVALPQVNAIPQQGHSVPPV------VPAAAAAASGR
MSMEG_3147|M.smegmatis_MC2_155      SETVVNRILQTVALPQVNALPQQGHSVPPA------VPAAAAAASGR
TH_3229|M.thermoresistible__bu      AETVINRILQTVALPQVNAVPQQAPPAQP-------MPTAATAASGR
MLBr_01810|M.leprae_Br4923          PEIVINRVLQTVALPQVNSFPQQGHSVPS-------VTQAAAAASGR
MAV_3299|M.avium_104                PEIVINRVLQTVALPQVNAVPQQGHSVPP-------VMQPAGAASGR
Mb1515|M.bovis_AF2122/97            PEIVINRVLQTVALPQVNAVPQQGHSVPP-------VMQAAAAASGR
Rv1479|M.tuberculosis_H37Rv         PEIVINRVLQTVALPQVNAVPQQGHSVPP-------VMQAAAAASGR
MMAR_2286|M.marinum_M               PEIVINRVLQTVALPQVNAVPQQGHSVPP-------VMQAAAAAGGR
MUL_1488|M.ulcerans_Agy99           PEIVINRVLQTVALPQVNAVPQQGHSVPP-------VMQAAAAAGGR
MAB_2726c|M.abscessus_ATCC_199      ADTAINRILQTVGLPQVNAVPQQGNSVPPAMVGTNNPVPAAHNAAPR
                                    .: .:**:****.*****:.***. .. .          .*  *. *