For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSPSNLPRTVGELRAAGHRERGVKQEIRENLLTALADGDNVWPGILGFDDTVIPQVERALIAGHDFVLLG ERGQGKTRLLRALAGLLDEWTPVIAGAELGEHPYTPITPESIRRAAQLGDDLPVAWKHRSERYTEKLATP DTSVADLVGDVDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQVSMLNVMEERDIQVRG YTLRLPLDVLVVASANPEDYTNRGRIITPIKDRFGAEIRTHYPLELEAEMGVIVQEAHLSAQVPDYLMQV LARFARYLRESRSIDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDVLRGKLEFES GEEGREQAVLEHLLRRATADTASRVLGGIDVGSLVTAVEGGSAVTTGERVSAKDVLAAVPGLPVVDRIAR KLGAESEGERAAALELALEALYLAKRVDKVCGEGQTVYG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0983 | - | - | 100% (459) | magnesium chelatase |
| M. bovis AF2122 / 97 | Mb1515 | moxR1 | 2e-05 | 25.54% (231) | transcriptional regulatory protein MOXR1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1877 | - | 0.0 | 83.95% (461) | putative magnesium chelatase |
| M. tuberculosis H37Rv | Rv0958 | - | 0.0 | 99.78% (459) | magnesium chelatase |
| M. leprae Br4923 | MLBr_01810 | moxR | 6e-05 | 31.43% (70) | MoxR homolog |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4541 | - | 0.0 | 94.36% (461) | magnesium chelatase |
| M. avium 104 | MAV_0412 | - | 7e-06 | 25.95% (131) | ATPase family protein associated with various cellular |
| M. smegmatis MC2 155 | MSMEG_5512 | - | 0.0 | 86.87% (457) | magnesium chelatase |
| M. thermoresistible (build 8) | TH_1334 | - | 0.0 | 86.21% (457) | POSSIBLE MAGNESIUM CHELATASE |
| M. ulcerans Agy99 | MUL_4711 | - | 0.0 | 94.79% (461) | magnesium chelatase |
| M. vanbaalenii PYR-1 | Mvan_4854 | - | 0.0 | 85.25% (461) | putative magnesium chelatase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0983|M.bovis_AF2122/97 --MSPSNLPRTVG----ELRAAGHRERGVKQEIRENLLTALADGDN---V
Rv0958|M.tuberculosis_H37Rv --MSPSNLPRTVG----ELRAAGHRERGVKQEIRENLLTALADGDN---V
MMAR_4541|M.marinum_M -MTSPSNLPRTVG----ELRASGHRERGVKQEIRENLLTALADGPDNAAV
MUL_4711|M.ulcerans_Agy99 MVTSPSNLPRTVG----ELRASGHRERGVKQEIRENLLTALADGPDNAAV
MSMEG_5512|M.smegmatis_MC2_155 MVSQPKDLPRTVG----ELRASGHRERGVKAEIRENLLAALAERR---DV
TH_1334|M.thermoresistible__bu -VTQPNDLPRTVG----ELRASGHRERGVKQEIRENLLAALAGGR---DV
Mflv_1877|M.gilvum_PYR-GCK -MTSPNDLPRTVG----ELRASGHRERTVKAEIRENLLAALASGAPVDEV
Mvan_4854|M.vanbaalenii_PYR-1 -MTSPNDLPRTVG----ELRASGHQERSIKAEIRENLLSALASGAGADAV
MLBr_01810|M.leprae_Br4923 -MTSAGGLPVGADGCSGPGGQSGPRAHEAPPGGADGLVAEVHTLERAIFE
MAV_0412|M.avium_104 -MTQP-TQPVTAS----PTAESAREALLALR-----------------AE
.. * .. :. .
Mb0983|M.bovis_AF2122/97 WPGILGFDDTVIPQVERALIAGHDFVLLGERGQGKTRLLRALAGLLDEWT
Rv0958|M.tuberculosis_H37Rv WPGILGFDDTVIPQVERALIAGHDFVLLGERGQGKTRLLRALAGLLDEWT
MMAR_4541|M.marinum_M WPGIVGFDDTVIPQLERALIAGHDFVLLGERGQGKTRLLRALTGLLDEWT
MUL_4711|M.ulcerans_Agy99 WPGIVGFDDTVIPQLERALIAGHDFVLLGERGQGKTRLLRALTGLLDEWT
MSMEG_5512|M.smegmatis_MC2_155 WPGILGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALTGLLDEWT
TH_1334|M.thermoresistible__bu WPGILGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALIGLLDEWT
Mflv_1877|M.gilvum_PYR-GCK WPGILGFEDTVLPQLERALIAGHDIVLLGERGQGKTRLLRGLTGMLDEWT
Mvan_4854|M.vanbaalenii_PYR-1 WPGILGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALTNLLDEWT
MLBr_01810|M.leprae_Br4923 VKRVIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFARVVGGTF
MAV_0412|M.avium_104 LAKAVVGQEGVVSGLVIALLCRGHVLLEGVPGVAKTLLVRALAAALQLEF
: :: :: : .*:. ..:* * * .** :. : :
Mb0983|M.bovis_AF2122/97 PVIAGAELGEHPYTPITPESIRRAAQLGDDLPVAWKHRSERYTEKLATPD
Rv0958|M.tuberculosis_H37Rv PVIAGAELGEHPYTPITPESIRRAAQLGDDLPVAWKHRSERYTEKLATPD
MMAR_4541|M.marinum_M PVIAGAELPEHPYRPITPESIRRAAQLKDDLPVAWKHRSERYTEKLATPD
MUL_4711|M.ulcerans_Agy99 PVIAGAELPEHPYRPITPESIRRAAQLKDDLPVAWKHRSERYTEKLATPD
MSMEG_5512|M.smegmatis_MC2_155 PVIAGSELGEHPYSPITPESIRRAADSGDDLPVEWRHRSERYTEKLATPD
TH_1334|M.thermoresistible__bu PVIAGSELGEHPYSPITPESIRRAADSGDDLPITWRHRSERYTEKLATPD
Mflv_1877|M.gilvum_PYR-GCK PVIAGAELGEHPYSPITPESIRRAADFGDDLPIAWRHRSERYTEKLATPD
Mvan_4854|M.vanbaalenii_PYR-1 PVIAGAELGEHPYSPITPESIRRAADSGDDLPITWRHRSERYTEKLATPD
MLBr_01810|M.leprae_Br4923 ARIQ-----------FTPDLVPTDIIG----TRIYRQGKEEFDTELGP--
MAV_0412|M.avium_104 KRVQ-----------FTPDLMPGDVTG----SLVYDARTAAFVFRPGP--
: :**: : . : . : . ..
Mb0983|M.bovis_AF2122/97 TSVADLVGDVDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
Rv0958|M.tuberculosis_H37Rv TSVADLVGDVDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
MMAR_4541|M.marinum_M TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
MUL_4711|M.ulcerans_Agy99 TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
MSMEG_5512|M.smegmatis_MC2_155 TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
TH_1334|M.thermoresistible__bu TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
Mflv_1877|M.gilvum_PYR-GCK TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
Mvan_4854|M.vanbaalenii_PYR-1 TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
MLBr_01810|M.leprae_Br4923 ----------------------------------VVVNFLLADEINRAPA
MAV_0412|M.avium_104 ----------------------------------VFTNLLLADEINRTPP
. .:: .:*: .
Mb0983|M.bovis_AF2122/97 RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPIK
Rv0958|M.tuberculosis_H37Rv RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPIK
MMAR_4541|M.marinum_M RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
MUL_4711|M.ulcerans_Agy99 RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
MSMEG_5512|M.smegmatis_MC2_155 RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
TH_1334|M.thermoresistible__bu RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
Mflv_1877|M.gilvum_PYR-GCK RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
Mvan_4854|M.vanbaalenii_PYR-1 RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
MLBr_01810|M.leprae_Br4923 KVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYLLPEAQR
MAV_0412|M.avium_104 KTQAALLEAMEERQVSVEGEAQPLPEPFIVAATQNPVEYEGTYQLPEAQL
: * ::*:.*:**.:.: * : ** .:* *: ** :: . : .
Mb0983|M.bovis_AF2122/97 DRFGAEIRTHYPLELEAEMGVIVQEAHLSAQVPDYLMQVLARFARYLRES
Rv0958|M.tuberculosis_H37Rv DRFGAEIRTHYPLELEAEMGVIVQEAHLSAQVSDYLMQVLARFARYLRES
MMAR_4541|M.marinum_M DRFGAEIRTHYPLELEAEMGVIAQEAHLSAQVPEYLLQVIARFARYLRES
MUL_4711|M.ulcerans_Agy99 DRFGAEIRTHYPLELEAEMGVIAQEAHLSAQVPDYLLQVIARFARYLRES
MSMEG_5512|M.smegmatis_MC2_155 DRFGAEIRTHYPLELEAEVGVIRQEAELAAEVPEYLLAVLARFARNLRES
TH_1334|M.thermoresistible__bu DRFGAEIRTHYPQQLEAEVGVITQEAHLAAEVPEYLLHILARFTRNLRES
Mflv_1877|M.gilvum_PYR-GCK DRFGAEIRTHYPLELDAEVGVIVQEAHMAAEVPDYLLQILARFARALRES
Mvan_4854|M.vanbaalenii_PYR-1 DRFGAEIRTHYPPELDAEVGVITQEAHLAAEVPDYLLQILARFARSLRES
MLBr_01810|M.leprae_Br4923 DRFLFKINVGYPSP-EEEREIIYR--MGVTP---PVPKQILNAG------
MAV_0412|M.avium_104 DRFLLKLNVTLPPR-EAEIAILHRHAHGFDPRDLSVVQPVAGPA------
*** ::.. * : * :: : : :
Mb0983|M.bovis_AF2122/97 RSIDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDV
Rv0958|M.tuberculosis_H37Rv RSIDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDV
MMAR_4541|M.marinum_M SSVDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLSTVIDV
MUL_4711|M.ulcerans_Agy99 SSVDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDV
MSMEG_5512|M.smegmatis_MC2_155 NSIDQRSGVSARFAIAAAETVAASARHRAAILGEDDPVARVVDLGTVIDV
TH_1334|M.thermoresistible__bu PSIDQRSGVSARFAIAAAETVAASARHRSAILGEDDPVARVVDLGTVIEV
Mflv_1877|M.gilvum_PYR-GCK SSVDQRSGVSARFAIAAAETVAASARHRAAVLNEQEPVARVVDLASILDV
Mvan_4854|M.vanbaalenii_PYR-1 SSIDQRSGVSARFAIAAAETVAASARHRAALLGEQDPVARVVDLQNVIDV
MLBr_01810|M.leprae_Br4923 -------------DLLRLQEISANNFVHHALVDYVVRVVTATRHPEQLGM
MAV_0412|M.avium_104 -------------DLAAGRDAVQQVRVADEVLGYIVDIVGATRSSPAL--
: . ::. :. .. :
Mb0983|M.bovis_AF2122/97 LRGKLEFESGEEGREQAVLEHLLRRATADTASRVLGGIDVGSLVTAVEGG
Rv0958|M.tuberculosis_H37Rv LRGKLEFESGEEGREQAVLEHLLRRATADTASRVLGGIDVGSLVTAVEGG
MMAR_4541|M.marinum_M LRGKLEFESGEEGREQAVLEHLLRRATADTASRALGGIDVGTLVSAVEGG
MUL_4711|M.ulcerans_Agy99 LRGKLEFESGEEGREQAVLEHLLRRATADTASRALGGIDVGTLVSAVEGG
MSMEG_5512|M.smegmatis_MC2_155 LRGKLEFETGEEGREQAVLEHLLRRATADTAQRLLGGIDVGPLVAAIEEG
TH_1334|M.thermoresistible__bu LRGKLEFESGEEGRELAILEHLLRRATADTAQRLLGGIDVGPLVAAVEEG
Mflv_1877|M.gilvum_PYR-GCK LRGKLEFESGEEGREQAILEHLLRRATAETAQRLLGGIDVGPIVTAVEGG
Mvan_4854|M.vanbaalenii_PYR-1 LRGKLEFESGEEGREQAVLEHLLRRATAETAQRLLGGIDVGPIVTAVENG
MLBr_01810|M.leprae_Br4923 NDVKTWISFGASPRASLGIIKASRSLALVRGRDYVIPQDVIEVIPDVLRH
MAV_0412|M.avium_104 -------QLGVSPRGATALLATARSWSWLSGRNYVTPDDVKAMARPTLRH
. * . * : * : . : ** :
Mb0983|M.bovis_AF2122/97 SAVTTGERVSAKDVLAAVPGLPVVDRIARKLGAESEGERAAALELALEAL
Rv0958|M.tuberculosis_H37Rv SAVTTGERVSAKDVLAAVPGLPVVDRIARKLGAESEGERAAALELALEAL
MMAR_4541|M.marinum_M SAVTTGERVSAKDVLAAVPGLPVVETIARKLDAESEGERAAALELALEAL
MUL_4711|M.ulcerans_Agy99 SAVTTGERVSAKDVLAAVPGLPVVETIARKLNAESEGERAAALELALEAL
MSMEG_5512|M.smegmatis_MC2_155 SPVTTGERVSAKDVVAALPDLPAIDAIAHRLNAVSVGQRAAAIELALEAL
TH_1334|M.thermoresistible__bu SPVTTGERVSAKDVLAALPDLPVIDTITTRLGAQSIGQRAAAVELALEAL
Mflv_1877|M.gilvum_PYR-GCK SPVTTGDRVSARDVLAALPEVSAVAEIQQRLGAQTDGQRAAAIELALEAL
Mvan_4854|M.vanbaalenii_PYR-1 SPVTTGERVSAREVLAAVPEVSAVAEIQQRLGATSEGQRAAAMELALEAL
MLBr_01810|M.leprae_Br4923 RLVLTYN--------ALADEISPEIVINRVLQTVALPQVNSFPQQGHSVP
MAV_0412|M.avium_104 RVMLRPE--------AELEGATCDGVLDGILASVPVPR------------
: : * . : * : . .
Mb0983|M.bovis_AF2122/97 YLAKRVDKVCGEGQTVYG
Rv0958|M.tuberculosis_H37Rv YLAKRVDKVCGEGQTVYG
MMAR_4541|M.marinum_M YLAKRVDKVSGEGQTVYG
MUL_4711|M.ulcerans_Agy99 YLAKRVDKVSGEGQTVYG
MSMEG_5512|M.smegmatis_MC2_155 YLAKRIDKVSGEGETVYG
TH_1334|M.thermoresistible__bu YLAKRIDKQTGEGETIYG
Mflv_1877|M.gilvum_PYR-GCK YLAKRIDKVSDQGETVYG
Mvan_4854|M.vanbaalenii_PYR-1 YLAKRIDKVSDEGETVYG
MLBr_01810|M.leprae_Br4923 SVTQAAAAASGR------
MAV_0412|M.avium_104 ------------------