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M. gilvum PYR-GCK Mflv_1877 (-)

annotation: putative magnesium chelatase
coordinates: 1953937 - 1955328
length: 463

VTSPNDLPRTVGELRASGHRERTVKAEIRENLLAALASGAPVDEVWPGILGFEDTVLPQLERALIAGHDI
VLLGERGQGKTRLLRGLTGMLDEWTPVIAGAELGEHPYSPITPESIRRAADFGDDLPIAWRHRSERYTEK
LATPDTSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAERIQVAMLNVMEERDI
QVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLKDRFGAEIRTHYPLELDAEVGVIVQEAHMAAEVPDY
LLQILARFARALRESSSVDQRSGVSARFAIAAAETVAASARHRAAVLNEQEPVARVVDLASILDVLRGKL
EFESGEEGREQAILEHLLRRATAETAQRLLGGIDVGPIVTAVEGGSPVTTGDRVSARDVLAALPEVSAVA
EIQQRLGAQTDGQRAAAIELALEALYLAKRIDKVSDQGETVYG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1877--100% (463)putative magnesium chelatase
M. gilvum PYR-GCKMflv_0039-2e-0527.59% (116) ATPase
M. gilvum PYR-GCKMflv_0476-8e-0523.42% (269) ATPase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0983-0.083.95% (461) magnesium chelatase
M. tuberculosis H37RvRv0958-0.083.73% (461) magnesium chelatase
M. leprae Br4923MLBr_01810moxR2e-0532.86% (70) MoxR homolog
M. abscessus ATCC 19977MAB_0389c-1e-0525.95% (131) putative regulatory protein
M. marinum MMMAR_4541-0.084.02% (463) magnesium chelatase
M. avium 104MAV_0412-2e-0625.95% (131) ATPase family protein associated with various cellular
M. smegmatis MC2 155MSMEG_5512-0.086.83% (463) magnesium chelatase
M. thermoresistible (build 8)TH_1334-0.086.61% (463) POSSIBLE MAGNESIUM CHELATASE
M. ulcerans Agy99MUL_4711-0.084.23% (463) magnesium chelatase
M. vanbaalenii PYR-1Mvan_4854-0.092.22% (463) putative magnesium chelatase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0983|M.bovis_AF2122/97            --MSPSNLP----RTVGELRAAGHRERGVKQEIRENLLTALADGDN---V
Rv0958|M.tuberculosis_H37Rv         --MSPSNLP----RTVGELRAAGHRERGVKQEIRENLLTALADGDN---V
MMAR_4541|M.marinum_M               -MTSPSNLP----RTVGELRASGHRERGVKQEIRENLLTALADGPDNAAV
MUL_4711|M.ulcerans_Agy99           MVTSPSNLP----RTVGELRASGHRERGVKQEIRENLLTALADGPDNAAV
Mflv_1877|M.gilvum_PYR-GCK          -MTSPNDLP----RTVGELRASGHRERTVKAEIRENLLAALASGAPVDEV
Mvan_4854|M.vanbaalenii_PYR-1       -MTSPNDLP----RTVGELRASGHQERSIKAEIRENLLSALASGAGADAV
MSMEG_5512|M.smegmatis_MC2_155      MVSQPKDLP----RTVGELRASGHRERGVKAEIRENLLAALAERR---DV
TH_1334|M.thermoresistible__bu      -VTQPNDLP----RTVGELRASGHRERGVKQEIRENLLAALAGGR---DV
MAB_0389c|M.abscessus_ATCC_199      -MTQAT--------TTGSSGETARNALAALR-----------------EQ
MAV_0412|M.avium_104                -MTQPTQP-----VTASPTAESAREALLALR-----------------AE
MLBr_01810|M.leprae_Br4923          -MTSAGGLPVGADGCSGPGGQSGPRAHEAPPGGADGLVAEVHTLERAIFE
                                       ..           .    :. .                         

Mb0983|M.bovis_AF2122/97            WPGILGFDDTVIPQVERALIAGHDFVLLGERGQGKTRLLRALAGLLDEWT
Rv0958|M.tuberculosis_H37Rv         WPGILGFDDTVIPQVERALIAGHDFVLLGERGQGKTRLLRALAGLLDEWT
MMAR_4541|M.marinum_M               WPGIVGFDDTVIPQLERALIAGHDFVLLGERGQGKTRLLRALTGLLDEWT
MUL_4711|M.ulcerans_Agy99           WPGIVGFDDTVIPQLERALIAGHDFVLLGERGQGKTRLLRALTGLLDEWT
Mflv_1877|M.gilvum_PYR-GCK          WPGILGFEDTVLPQLERALIAGHDIVLLGERGQGKTRLLRGLTGMLDEWT
Mvan_4854|M.vanbaalenii_PYR-1       WPGILGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALTNLLDEWT
MSMEG_5512|M.smegmatis_MC2_155      WPGILGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALTGLLDEWT
TH_1334|M.thermoresistible__bu      WPGILGFEDTVIPQLERALIAGHDVVLLGERGQGKTRLLRALIGLLDEWT
MAB_0389c|M.abscessus_ATCC_199      IAIVVVGQDSVVSGLVVALLCRGHVLLEGVPGVAKTLLVRTLS-------
MAV_0412|M.avium_104                LAKAVVGQEGVVSGLVIALLCRGHVLLEGVPGVAKTLLVRALA-------
MLBr_01810|M.leprae_Br4923          VKRVIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETFA-------
                                        :  :: ::  :  .*:.  ..:* *  * .**  :. :        

Mb0983|M.bovis_AF2122/97            PVIAGAELGEHPYTPITPESIRRAAQLGDDLPVAWKHRSERYTEKLATPD
Rv0958|M.tuberculosis_H37Rv         PVIAGAELGEHPYTPITPESIRRAAQLGDDLPVAWKHRSERYTEKLATPD
MMAR_4541|M.marinum_M               PVIAGAELPEHPYRPITPESIRRAAQLKDDLPVAWKHRSERYTEKLATPD
MUL_4711|M.ulcerans_Agy99           PVIAGAELPEHPYRPITPESIRRAAQLKDDLPVAWKHRSERYTEKLATPD
Mflv_1877|M.gilvum_PYR-GCK          PVIAGAELGEHPYSPITPESIRRAADFGDDLPIAWRHRSERYTEKLATPD
Mvan_4854|M.vanbaalenii_PYR-1       PVIAGAELGEHPYSPITPESIRRAADSGDDLPITWRHRSERYTEKLATPD
MSMEG_5512|M.smegmatis_MC2_155      PVIAGSELGEHPYSPITPESIRRAADSGDDLPVEWRHRSERYTEKLATPD
TH_1334|M.thermoresistible__bu      PVIAGSELGEHPYSPITPESIRRAADSGDDLPITWRHRSERYTEKLATPD
MAB_0389c|M.abscessus_ATCC_199      -----------------------------------AALSLDFKRVQFTPD
MAV_0412|M.avium_104                -----------------------------------AALQLEFKRVQFTPD
MLBr_01810|M.leprae_Br4923          -----------------------------------RVVGGTFARIQFTPD
                                                                             : .   ***

Mb0983|M.bovis_AF2122/97            TSVADLVGDVDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
Rv0958|M.tuberculosis_H37Rv         TSVADLVGDVDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
MMAR_4541|M.marinum_M               TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
MUL_4711|M.ulcerans_Agy99           TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
Mflv_1877|M.gilvum_PYR-GCK          TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
Mvan_4854|M.vanbaalenii_PYR-1       TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
MSMEG_5512|M.smegmatis_MC2_155      TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
TH_1334|M.thermoresistible__bu      TSVADLVGDIDPIKVAEGRSLGDPETIAYGLIPRAHRGIVAVNELPDLAE
MAB_0389c|M.abscessus_ATCC_199      LMPGDVTGSLVYDARTAAFEFRAGPVFTN---------LLLADEINRTPP
MAV_0412|M.avium_104                LMPGDVTGSLVYDARTAAFVFRPGPVFTN---------LLLADEINRTPP
MLBr_01810|M.leprae_Br4923          LVPTDIIGTRIYRQGKEEFDTELGPVVVN---------FLLADEINRAPA
                                        *: *                 ...          :: .:*:   . 

Mb0983|M.bovis_AF2122/97            RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPIK
Rv0958|M.tuberculosis_H37Rv         RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPIK
MMAR_4541|M.marinum_M               RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
MUL_4711|M.ulcerans_Agy99           RIQVSMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
Mflv_1877|M.gilvum_PYR-GCK          RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
Mvan_4854|M.vanbaalenii_PYR-1       RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
MSMEG_5512|M.smegmatis_MC2_155      RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
TH_1334|M.thermoresistible__bu      RIQVAMLNVMEERDIQVRGYTLRLPLDVLVVASANPEDYTNRGRIITPLK
MAB_0389c|M.abscessus_ATCC_199      KTQAALLEAMEERQVTVDGTPRPLPDPFIVAATQNPIEYEGTYQLPEAQL
MAV_0412|M.avium_104                KTQAALLEAMEERQVSVEGEAQPLPEPFIVAATQNPVEYEGTYQLPEAQL
MLBr_01810|M.leprae_Br4923          KVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVYLLPEAQR
                                    : * ::*:.*:**.: : * .  **  .:* *: ** :: .   :  .  

Mb0983|M.bovis_AF2122/97            DRFGAEIRTHYPLELEAEMGVIVQEAHLSAQVPDYLMQVLARFARYLRES
Rv0958|M.tuberculosis_H37Rv         DRFGAEIRTHYPLELEAEMGVIVQEAHLSAQVSDYLMQVLARFARYLRES
MMAR_4541|M.marinum_M               DRFGAEIRTHYPLELEAEMGVIAQEAHLSAQVPEYLLQVIARFARYLRES
MUL_4711|M.ulcerans_Agy99           DRFGAEIRTHYPLELEAEMGVIAQEAHLSAQVPDYLLQVIARFARYLRES
Mflv_1877|M.gilvum_PYR-GCK          DRFGAEIRTHYPLELDAEVGVIVQEAHMAAEVPDYLLQILARFARALRES
Mvan_4854|M.vanbaalenii_PYR-1       DRFGAEIRTHYPPELDAEVGVITQEAHLAAEVPDYLLQILARFARSLRES
MSMEG_5512|M.smegmatis_MC2_155      DRFGAEIRTHYPLELEAEVGVIRQEAELAAEVPEYLLAVLARFARNLRES
TH_1334|M.thermoresistible__bu      DRFGAEIRTHYPQQLEAEVGVITQEAHLAAEVPEYLLHILARFTRNLRES
MAB_0389c|M.abscessus_ATCC_199      DRFLMKLNVSLPERDQEIAILDRHAHGFDPRNLSHVTPVAS--AADLAAG
MAV_0412|M.avium_104                DRFLLKLNVTLPPREAEIAILHRHAHGFDPRDLSVVQPVAG--PADLAAG
MLBr_01810|M.leprae_Br4923          DRFLFKINVGYPSPEEEREIIYR--MGVTP---PVPKQILN--AGDLLRL
                                    ***  ::..  *        :      . .        :    .  *   

Mb0983|M.bovis_AF2122/97            RSIDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDV
Rv0958|M.tuberculosis_H37Rv         RSIDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDV
MMAR_4541|M.marinum_M               SSVDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLSTVIDV
MUL_4711|M.ulcerans_Agy99           SSVDQRSGVSARFAIAAAETVAAAARHRGAVLGETDPVARVVDLGTVIDV
Mflv_1877|M.gilvum_PYR-GCK          SSVDQRSGVSARFAIAAAETVAASARHRAAVLNEQEPVARVVDLASILDV
Mvan_4854|M.vanbaalenii_PYR-1       SSIDQRSGVSARFAIAAAETVAASARHRAALLGEQDPVARVVDLQNVIDV
MSMEG_5512|M.smegmatis_MC2_155      NSIDQRSGVSARFAIAAAETVAASARHRAAILGEDDPVARVVDLGTVIDV
TH_1334|M.thermoresistible__bu      PSIDQRSGVSARFAIAAAETVAASARHRSAILGEDDPVARVVDLGTVIEV
MAB_0389c|M.abscessus_ATCC_199      RAAVGQVLVAPEVLAYVVDVIRATRQSPSL---------QLGASPRAATA
MAV_0412|M.avium_104                RDAVQQVRVADEVLGYIVDIVGATRSSPAL---------QLGVSPRGATA
MLBr_01810|M.leprae_Br4923          QEISANNFVHHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASPRASLG
                                         .  *   .    .  : *:                .         

Mb0983|M.bovis_AF2122/97            LRGKLEFESGEEGREQAVLEHLLRRATADTASRVLGGIDVGSLVTAVEGG
Rv0958|M.tuberculosis_H37Rv         LRGKLEFESGEEGREQAVLEHLLRRATADTASRVLGGIDVGSLVTAVEGG
MMAR_4541|M.marinum_M               LRGKLEFESGEEGREQAVLEHLLRRATADTASRALGGIDVGTLVSAVEGG
MUL_4711|M.ulcerans_Agy99           LRGKLEFESGEEGREQAVLEHLLRRATADTASRALGGIDVGTLVSAVEGG
Mflv_1877|M.gilvum_PYR-GCK          LRGKLEFESGEEGREQAILEHLLRRATAETAQRLLGGIDVGPIVTAVEGG
Mvan_4854|M.vanbaalenii_PYR-1       LRGKLEFESGEEGREQAVLEHLLRRATAETAQRLLGGIDVGPIVTAVENG
MSMEG_5512|M.smegmatis_MC2_155      LRGKLEFETGEEGREQAVLEHLLRRATADTAQRLLGGIDVGPLVAAIEEG
TH_1334|M.thermoresistible__bu      LRGKLEFESGEEGRELAILEHLLRRATADTAQRLLGGIDVGPLVAAVEEG
MAB_0389c|M.abscessus_ATCC_199      LLATSRAWAWLSGRNYVTPDDVKAMARPTLRHRIG--------LRPEAEL
MAV_0412|M.avium_104                LLATARSWSWLSGRNYVTPDDVKAMARPTLRHRVM--------LRPEAEL
MLBr_01810|M.leprae_Br4923          IIKASRSLALVRGRDYVIPQDVIEVIPDVLRHRLV--------LTYNALA
                                    :    .  :   **: .  :.:          *          :      

Mb0983|M.bovis_AF2122/97            SAVTTGERVSAKDVLAAVPGLPVVDRIARKLGAESEGERAAALELALEAL
Rv0958|M.tuberculosis_H37Rv         SAVTTGERVSAKDVLAAVPGLPVVDRIARKLGAESEGERAAALELALEAL
MMAR_4541|M.marinum_M               SAVTTGERVSAKDVLAAVPGLPVVETIARKLDAESEGERAAALELALEAL
MUL_4711|M.ulcerans_Agy99           SAVTTGERVSAKDVLAAVPGLPVVETIARKLNAESEGERAAALELALEAL
Mflv_1877|M.gilvum_PYR-GCK          SPVTTGDRVSARDVLAALPEVSAVAEIQQRLGAQTDGQRAAAIELALEAL
Mvan_4854|M.vanbaalenii_PYR-1       SPVTTGERVSAREVLAAVPEVSAVAEIQQRLGATSEGQRAAAMELALEAL
MSMEG_5512|M.smegmatis_MC2_155      SPVTTGERVSAKDVVAALPDLPAIDAIAHRLNAVSVGQRAAAIELALEAL
TH_1334|M.thermoresistible__bu      SPVTTGERVSAKDVLAALPDLPVIDTITTRLGAQSIGQRAAAVELALEAL
MAB_0389c|M.abscessus_ATCC_199      EGATSDRVLDGILVTVPVPR------------------------------
MAV_0412|M.avium_104                EGATCDGVLDGILASVPVPR------------------------------
MLBr_01810|M.leprae_Br4923          DEISPEIVINRVLQTVALPQVNSFPQQGHSVPSVTQAAAAASGR------
                                    .  :    :.     ..:*                               

Mb0983|M.bovis_AF2122/97            YLAKRVDKVCGEGQTVYG
Rv0958|M.tuberculosis_H37Rv         YLAKRVDKVCGEGQTVYG
MMAR_4541|M.marinum_M               YLAKRVDKVSGEGQTVYG
MUL_4711|M.ulcerans_Agy99           YLAKRVDKVSGEGQTVYG
Mflv_1877|M.gilvum_PYR-GCK          YLAKRIDKVSDQGETVYG
Mvan_4854|M.vanbaalenii_PYR-1       YLAKRIDKVSDEGETVYG
MSMEG_5512|M.smegmatis_MC2_155      YLAKRIDKVSGEGETVYG
TH_1334|M.thermoresistible__bu      YLAKRIDKQTGEGETIYG
MAB_0389c|M.abscessus_ATCC_199      ------------------
MAV_0412|M.avium_104                ------------------
MLBr_01810|M.leprae_Br4923          ------------------