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ASNMRTGAHFTPIGGAPGIERLQAGLRGEGFTPHRHDTYAIGMTLSGVQTFSYRGTKRVCLPGQWHVLHP DELHDGVPGTDDGFAYRIVYVDPALVFESSDRRLPFVADPIVDGAKVPRALARYLQRDGTDDEDDDLAAT DVVTVIADMLSAHSSAGRVVPQRLDRAAITRVRESLMDNPSRRYRAADVERIAGMDRWSVARQFRAAFGT SPSRFRTMRQLQLARSLIVGGAALAEAAHAAGFADQAHFTRKFKAAYGLTPAAWSGAVRHKPPVTSSTDP LT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5465 | - | - | 100% (283) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_2590 | - | 3e-13 | 25.83% (240) | AraC-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3488 | - | 1e-09 | 24.68% (154) | transcriptional regulator, AraC family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2899 | - | 5e-06 | 32.93% (82) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0066c | - | 1e-08 | 28.74% (254) | AraC family transcriptional regulator |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_0221 | - | 9e-08 | 27.27% (143) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_2588 | - | 5e-09 | 31.68% (101) | PUTATIVE putative transcriptional regulator, AraC family |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3996 | - | 2e-10 | 29.37% (126) | helix-turn-helix domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2899|M.gilvum_PYR-GCK ---------------------------------MRAKDLVDARYAEP---
Mvan_3996|M.vanbaalenii_PYR-1 ------MDATGVDRRVPARLVLATRDGQLPGADLRVYQFHSHQTQVPPLR
MSMEG_5465|M.smegmatis_MC2_155 -------MASNMRTGAHFTPIGGAPGIERLQAGLRGEGFTPHRHDTYAIG
MAB_0066c|M.abscessus_ATCC_199 ------MVWTGAAVIEPGRLVYRGALGDTHRHTHAAVQIAIALDGTLQLT
MAV_0221|M.avium_104 ------MYRPSPPLAEHIEYFGYWRGDEALGVHTSRALPRGAVTAIIDVG
TH_2588|M.thermoresistible__bu VRDPARIEIGGHPAAPLRPFVTGYTGFDLRGFEPGVHVGMPSHTLTAVLT
Mflv_2899|M.gilvum_PYR-GCK --------------ITVDDLAAAAGLSRAHFSRMFT--------------
Mvan_3996|M.vanbaalenii_PYR-1 DIAVIGWQSRAQIALRCGAIRSRAQMSPGDFSILRPGYESTWQWSRGFQA
MSMEG_5465|M.smegmatis_MC2_155 --------MTLSGVQTFSYRGTKRVCLPGQWHVLHP-----DELHDGVPG
MAB_0066c|M.abscessus_ATCC_199 DG------------ADRRVSTRAAVIPAGAQHTVHG----------GTST
MAV_0221|M.avium_104 GR------------TDLGFYASDARTPLTVPPAFAAG----AGATAYVVR
TH_2588|M.thermoresistible__bu FG------EPLEIDVPSGLSGTSGRYPSMASGLLAQS---------ISIR
.
Mflv_2899|M.gilvum_PYR-GCK -------RTFGESP--------------------------RAYLQTRRLE
Mvan_3996|M.vanbaalenii_PYR-1 TVLYLNERRFADFASEVFDHHVDSVTIRESFQVQDSVIHHGLFLLATELR
MSMEG_5465|M.smegmatis_MC2_155 TDDGFAYRIVYVDPALVFESSDRRLPFVADPIVDGAKVPRALARYLQRDG
MAB_0066c|M.abscessus_ATCC_199 GLMIYLEPTCFEGRALG--------ALFDNAARDDATAWCAAASELSDIQ
MAV_0221|M.avium_104 VAPAHTVMTIHFRPAGALAFLGSPLSDLEDALVGLEDLWGRDAALLREQL
TH_2588|M.thermoresistible__bu HRGAQRGVKLSFTPLGARMVFGMPAGALANSVVPLSDVLADLWPELEDRL
Mflv_2899|M.gilvum_PYR-GCK R----------------AASLLRHTDRS----------------------
Mvan_3996|M.vanbaalenii_PYR-1 RDEFGAALYRDALVTQLCVHLLRHHAESRLRAHRHPGALNAAQAQQVTDY
MSMEG_5465|M.smegmatis_MC2_155 TDDEDDDLAATDVVTVIADMLSAHSSAGRVVPQR----LDRAAITRVRES
MAB_0066c|M.abscessus_ATCC_199 DDSSSAESVIARLVGDVHASEPHESVREAIRLLP----------------
MAV_0221|M.avium_104 IDAGSPPRRVALLQAFLVRRMRRNAVWPPARLAP--------------VL
TH_2588|M.thermoresistible__bu GAAATWPHRFRVLDDVLARAVARTMCAGMFDVRP---------EVAAAWQ
Mflv_2899|M.gilvum_PYR-GCK -----VADICVMVGLQSVGS----FTTSFARAYGLPPAAYR-----ASMP
Mvan_3996|M.vanbaalenii_PYR-1 IEHNLDSDLCLSSLARVAGLSQYHFARLFKKRFGAPPHAYVQRRRIERAR
MSMEG_5465|M.smegmatis_MC2_155 LMDNPSRRYRAADVERIAGMDRWSVARQFRAAFGTSPSRFRTMRQLQLAR
MAB_0066c|M.abscessus_ATCC_199 --GMLTGPVRLAEVARVVHLSADRLGRMFARDTGMSFPAYVRWARLIRTI
MAV_0221|M.avium_104 RGADLDPSMRVSKAQELSGLSRKRFAALFRCEVGLSPKAYLRVLRLQAAL
TH_2588|M.thermoresistible__bu RLVDSRGQVRVGDLAHDLGCSRRHLTARFREEFGLTPKTLARILRLEQAV
. . * * .
Mflv_2899|M.gilvum_PYR-GCK SAAVHAR-IPSCILQRDTRPKADSRVKTAHGEKTGANASP----------
Mvan_3996|M.vanbaalenii_PYR-1 HLVLHSD-MPLKEVVGVTGFCDQSHLTRAFRRAFDITPAELRRSSD----
MSMEG_5465|M.smegmatis_MC2_155 SLIVGG--AALAEAAHAAGFADQAHFTRKFKAAYGLTPAAWSGAVRHKPP
MAB_0066c|M.abscessus_ATCC_199 EVARTG--GTLTDAAHAAGFSDSSHANRAFHEMFGITPVELHRSVQLS--
MAV_0221|M.avium_104 RALDTP--ARGATIAADLGYFDQAHFVREFRAFTGATPTQYARRRSSMPG
TH_2588|M.thermoresistible__bu GLVAAAGAPAWAEVSAAAGYADQAHLVRDWRSFTGRTPSSWFDGDVLVDG
.:: . ..
Mflv_2899|M.gilvum_PYR-GCK ---------
Mvan_3996|M.vanbaalenii_PYR-1 ---------
MSMEG_5465|M.smegmatis_MC2_155 VTSSTDPLT
MAB_0066c|M.abscessus_ATCC_199 ---------
MAV_0221|M.avium_104 HVELAR---
TH_2588|M.thermoresistible__bu RPHG-----