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MSLDSSRAVLSSGDELHKRATRKAVLRLLPVMCVVYFMAYIDRTNVALAKTHLDTDVGISAAAFGFGAGI FFISYAFLEVPSNLVMYRVGPRRWIARIALTWGALSALMMFVQGDMSFYVMRFLLGAAEAGLYPALMYMV TLWFAQSYRATVVGFIYLAPTIALVVGGPMGGALMELDSAMGLHGWQWMFLIEGLVTMLVGVLVWFKLPQ SPTEAKWLTPDEARILSERAAGAHHETVTHLRGNLGKAFGRPFVIVVALIYFFNQITNVGIVFNIPAIVE DLDISGSFVIGLLSGSAGIGATIGVLVVPRLFAWYQREAAAVGILAAATLVTSVLFMLSTSAFARIILIA ISMIFVFGTLPLFWSIAMARMSGLVAAASLAFINTIGLIGGFVGPYLFGLAETATHNPSAGFYIVIVSSV IGVALAPVLAHAIRREDSTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5347 | - | - | 100% (440) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_6375 | - | 6e-89 | 43.52% (409) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_2537 | - | 1e-53 | 32.21% (444) | transporter protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1699c | - | 9e-49 | 29.55% (423) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_0241 | - | 9e-09 | 29.00% (200) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1672c | - | 9e-49 | 29.55% (423) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0365c | - | 3e-09 | 24.94% (413) | sugar-transport integral membrane protein |
| M. marinum M | MMAR_0596 | - | 2e-65 | 33.10% (435) | integral membrane transport protein |
| M. avium 104 | MAV_1387 | - | 6e-07 | 22.70% (185) | drug transporter |
| M. thermoresistible (build 8) | TH_3965 | - | 2e-09 | 24.77% (214) | PUTATIVE drug transporter |
| M. ulcerans Agy99 | MUL_0838 | - | 4e-08 | 22.63% (190) | transmembrane carbohydrate transport protein |
| M. vanbaalenii PYR-1 | Mvan_0664 | - | 4e-08 | 26.50% (200) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1699c|M.bovis_AF2122/97 -------MATIAA---SPTHNALGKAARRLLPLLFVLYVINFVDRANISV
Rv1672c|M.tuberculosis_H37Rv -------MATIAA---SPTHNALGKAARRLLPLLFVLYVINFVDRANISV
MMAR_0596|M.marinum_M -------MAVLDTGERSLEARTIRKLGIRIVPFLMALYFVNYLDRTNLGI
Mflv_0241|M.gilvum_PYR-GCK -----------------------MSRRWLALGVLTLAVLLIGVDGTVLAL
Mvan_0664|M.vanbaalenii_PYR-1 -----------------------MTRRWSALAVLTLAVLLIGIDGTVLAL
MUL_0838|M.ulcerans_Agy99 --------MTASPQVNETEGRPVVGRPGAVLFTVCAALFLVVVDVTVLHV
MAV_1387|M.avium_104 ---------------------------------MMIGFFMIMVDSTIVAI
TH_3965|M.thermoresistible__bu VTSVDAGRSTMSEVFTAYAPRSAAANPWHALWAMLIGFFMILVDATIVPV
MSMEG_5347|M.smegmatis_MC2_155 --MSLDSSRAVLSSGDELHKRATRKAVLRLLPVMCVVYFMAYIDRTNVAL
MAB_0365c|M.abscessus_ATCC_199 -------------MSLITDLRSTSRLGVMVAVTAAAVGVIYGYDSSNIAG
.: * : :
Mb1699c|M.bovis_AF2122/97 AALAMNADLRLSATAYGTAAGVFFLGYVLFQVPANAALARFGAGRTLTAV
Rv1672c|M.tuberculosis_H37Rv AALAMNADLRLSATAYGTAAGVFFLGYVLFQVPANAALARFGAGRTLTAV
MMAR_0596|M.marinum_M ARADISAHLQLTATMFGLASGIFFIGYVLVEVPSNLALDRYGARRWLARI
Mflv_0241|M.gilvum_PYR-GCK ATPFISADLGATGTELLWIGDIYSFVLAALLVTMGSLGDRVGHRKLLLCG
Mvan_0664|M.vanbaalenii_PYR-1 ATPFISADLGATGTQILWIGDIYSFVLAALLISMGSLGDRIGHRKLLLCG
MUL_0838|M.ulcerans_Agy99 AAPRIAEELSPSPTEFLWIVDIYPLIMASLMLMAGAASDRFGRKRLLMTG
MAV_1387|M.avium_104 ANPTIMADLHIGYDTVVWVTSAYLLGYAVVLLVAGRLGDRFGTKNLYLIG
TH_3965|M.thermoresistible__bu ANLEIMADLGADYTAVIWVTSAYLLAYAVPLLIAGRLGDRFGPRTMYLIG
MSMEG_5347|M.smegmatis_MC2_155 AKTHLDTDVGISAAAFGFGAGIFFISYAFLEVPSNLVMYRVGPRRWIARI
MAB_0365c|M.abscessus_ATCC_199 ALLFLTEDLHLSTHDQQVAATAVVIGEIFGALIGGPLSNKIGRKRSMVLV
* : .: : : . : *
Mb1699c|M.bovis_AF2122/97 VLAWGVCSAATALVTSAHTLYLARFALGVAEGGFFPGVIAYLTVWFPCAQ
Rv1672c|M.tuberculosis_H37Rv VLAWGVCSAATALVTSAHTLYLARFALGVAEGGFFPGVIAYLTVWFPCAQ
MMAR_0596|M.marinum_M AVSWGIVVVATGFAPNATTLLVLRFLLGVAEAGLFPGVIYYLSRWFPRDY
Mflv_0241|M.gilvum_PYR-GCK ATAFSAVSALTAYSTSPEMLIGTRALLGMAGATLAPATLALIRGLFPDSR
Mvan_0664|M.vanbaalenii_PYR-1 ATAFAVISAVTAYSTSPQMLILTRALLGMAGATLTPATLALIRGLFPDQR
MUL_0838|M.ulcerans_Agy99 LVIFGLVSIPAAFAATPLMLILARSVMAVGAAMILPATVSLLRVAFPDRA
MAV_1387|M.avium_104 LAVFTVASVWCGLAGSAAMLIAARVVQGVGAGVMTPQTLSTITRIFPAER
TH_3965|M.thermoresistible__bu LAIFTAASLWCGLAGTIGMLIAARVLQGLGAALLTPQTLSMITRIFPADR
MSMEG_5347|M.smegmatis_MC2_155 ALTWGALSALMMFVQGDMSFYVMRFLLGAAEAGLYPALMYMVTLWFAQSY
MAB_0365c|M.abscessus_ATCC_199 AATFGIFSLLSALAVDLNTLAAARFLLGLTVGVSVVVVPVFVAESSPTKI
: : * . . : .
Mb1699c|M.bovis_AF2122/97 -RARAVATFLLAIPVANTVGLPLSGLIVGHVH-MAGLPGWRAMFVIEALP
Rv1672c|M.tuberculosis_H37Rv -RARAVATFLLAIPVANTVGLPLSGLIVGHVH-MAGLPGWRAMFVIEALP
MMAR_0596|M.marinum_M -RARVVALFMMASPIAAALGTPLAAWLIHLGNGVFGLAGWQFMMIAVGVP
Mflv_0241|M.gilvum_PYR-GCK ERSIAVGIWASAFSAGAALGPVVGGVLLEHFW-------WGSVFLINIPV
Mvan_0664|M.vanbaalenii_PYR-1 ERSIAVGIWASAFSAGAALGPVVGGVLLEHFW-------WGSVFLINIPV
MUL_0838|M.ulcerans_Agy99 ERMRAVGIWSAVSAVGAAIGPLMGGLLVEYFW-------WGAIFLINVPL
MAV_1387|M.avium_104 -RGVAVSVWSATAGAASLAGPLAGGVLVDGLG-------WQWIFFVNVPI
TH_3965|M.thermoresistible__bu -RGVPMGVWGATAGVATLIGPLAGGVLVDGLG-------WQWIFIVNVPI
MSMEG_5347|M.smegmatis_MC2_155 -RATVVGFIYLAPTIALVVGGPMGGALMELDS-AMGLHGWQWMFLIEGLV
MAB_0365c|M.abscessus_ATCC_199 -RGSMLVLYQLACVTGIIAGYLIAWALSSTGS-------WRLMLGLAAVP
* : . . * . : * ::
Mb1699c|M.bovis_AF2122/97 ALLLAPLLRRLLPD---NPQRASWLTPEERAELSARLTEDTPAPTG----
Rv1672c|M.tuberculosis_H37Rv ALLLAPLLRRLLPD---NPQRASWLTPEERAELSARLTEDTPAPTG----
MMAR_0596|M.marinum_M AIVLGFACWYYLVD---RPGDAAWLEPDERQWLVDTLAEEQRQVAGDF--
Mflv_0241|M.gilvum_PYR-GCK MVILLVGGLVLLPEH-RDPDPGPWDLPSVALSMVGMLGIVYAIKEGFTGL
Mvan_0664|M.vanbaalenii_PYR-1 MVILLVGGVLLLPEH-RNPDPGPWDLPSVALSMVGMLAVVYAVKEGFAGL
MUL_0838|M.ulcerans_Agy99 ALLVLLLVWRLVPES-RSQARLVLDGLSVSLSIVAVLTSVLAIKQATH--
MAV_1387|M.avium_104 GVLGLVLAYWLVPVL-PTQSHR-FDLVGVGLSGVGMLLIVFGLQQGQA--
TH_3965|M.thermoresistible__bu GIAGLVLGARLMPRL-PRQDQG-FDVLGMVLSAVGLFLIVFALQEAQT--
MSMEG_5347|M.smegmatis_MC2_155 TMLVGVLVWFKLPQ---SPTEAKWLTPDEARILSERAAGAHHETVTHLRG
MAB_0365c|M.abscessus_ATCC_199 AALVLIALLKLPDTARWYMMRGDRARAREVLSMVDRDVDIDHELDEIA--
Mb1699c|M.bovis_AF2122/97 -------------RSSGAGWDLVLFAVVYGG------LYFALYALQFFLP
Rv1672c|M.tuberculosis_H37Rv -------------RSSGAGWDLVLFAVVYGG------LYFALYALQFFLP
MMAR_0596|M.marinum_M ---------HFPLRRALTSPRIWALALVYFG------IAYGLYALTFFLP
Mflv_0241|M.gilvum_PYR-GCK VHGLGAEVVIAAAVGVAALTLFVRRQLRLP----HPLIDVRLFANPRFSG
Mvan_0664|M.vanbaalenii_PYR-1 AHGVGPDVAVAGLVGAAALTMFVRRQLRLP----APLIDVRLFANPRFSG
MUL_0838|M.ulcerans_Agy99 -HGIDPAAVGYVVIASVGLWWFIRRQISRQRRGIEPLLNVHLFTRAPFTS
MAV_1387|M.avium_104 -AHWQPWIWALIVAGVGFVTVFVFWQSVNVR---EPLIPLVIFSDRDFSL
TH_3965|M.thermoresistible__bu -HRWAPWIWGTLAGGAGVMAMFVIWQSANRR---HPLVPLQIFADRNFML
MSMEG_5347|M.smegmatis_MC2_155 -----------NLGKAFGRPFVIVVALIYFFN------QITNVGIVFNIP
MAB_0365c|M.abscessus_ATCC_199 ------EALRAEGGGSVRARLREMVTAPYRR------ATFFVVGLGFFIQ
Mb1699c|M.bovis_AF2122/97 QLVA----SLAHGTATLTAATLAALPYGVAALAMLAWSHRSIDRSGAQAG
Rv1672c|M.tuberculosis_H37Rv QLVA----SLAHGTATLTAATLAALPYGVAALAMLAWSHRSIDRSGAQAG
MMAR_0596|M.marinum_M SIISGFKKSFGIDFSIVQVGLIAAIPYTCAAVAMYLWS-RHADATGEQVW
Mflv_0241|M.gilvum_PYR-GCK VVGANLFSVLGLSGLVFFLSQYFQLVHGYGPLKAGLAELPAAVTATVFGV
Mvan_0664|M.vanbaalenii_PYR-1 VVAANLLSVLGLSGLVFFLSQYFQLVHGYGPLKAGLAELPAAVTATVFGV
MUL_0838|M.ulcerans_Agy99 AVLAVLLAVFSIVGLDLVFAQYLQNFLGFTPIKAALLLTPMAAATVVGSL
MAV_1387|M.avium_104 CNIGVAIISFAATAMMLPLTFYAQAVCGLSPTRSALLIAPMAIANGVFAP
TH_3965|M.thermoresistible__bu ANVGVATIGFVVTAMVLPAMFFAQAVCGLSPTGSALLIAPMAVASGVLAP
MSMEG_5347|M.smegmatis_MC2_155 AIVEDLDISGSFVIGLLSGSAGIGATIGVLVVPRLFAWYQREAAAVGILA
MAB_0365c|M.abscessus_ATCC_199 ITGINAVVYYGPRIFEAMGMSGYFAKLGLPALVQVAALLAVFISMSSIDR
Mb1699c|M.bovis_AF2122/97 HITLPTTAAGS---------------AALGAALSPMSPIVTLSWLTIAVA
Rv1672c|M.tuberculosis_H37Rv HITLPTTAAGS---------------AALGAALSPMSPIVTLSWLTIAVA
MMAR_0596|M.marinum_M HVAVPMLLGG----------------LAIPVALHLHTPVLVMVAVAITAM
Mflv_0241|M.gilvum_PYR-GCK LAGVAVRYFSHRSVLTTGLALVGTAMAALMASLLIFRPLTPYLPLGISLF
Mvan_0664|M.vanbaalenii_PYR-1 LAGVAVRYVSHRAVLATGLALVGVAMAAMTTSLLVFTPVAPYLPLGVALF
MUL_0838|M.ulcerans_Agy99 SAHLIVGRCGTRVAISAGLGLT----ASALLPLLTPGHNGQLLVFVGSLA
MAV_1387|M.avium_104 FVGKIVDRYHPRPVLGFGFSLLA---IALTWLTFEMSPATPIWRLVLPFF
TH_3965|M.thermoresistible__bu MAGRIVDRSHPTPVVGFGFSVVA---VGLTWLAVEMAPTTPIWRLVLPFV
MSMEG_5347|M.smegmatis_MC2_155 AATLVT----------------------SVLFMLSTSAFARIILIAISMI
MAB_0365c|M.abscessus_ATCC_199 MGRRPILMIGIGIMIVADALLVGVFAVGGSSFGGLLTFLGFLGIVLIAVG
. .
Mb1699c|M.bovis_AF2122/97 GILAAMPAFWSRCTAALAG----PRVAVAIATVNAVASLASFAGPYATGH
Rv1672c|M.tuberculosis_H37Rv GILAAMPAFWSRCTAALAG----PRVAVAIATVNAVASLASFAGPYATGH
MMAR_0596|M.marinum_M GVFAAIPSFWALPSNFLTG----TAAAGAIGLINSVGNLGGFAAPYLTGA
Mflv_0241|M.gilvum_PYR-GCK VVGVGLGLAFTVASDVILASVPKERAGAAAAVSETAYELGMALGIAVLGS
Mvan_0664|M.vanbaalenii_PYR-1 VVGVGLGLAFTVASDVILASVPRERAGAAAAVSETAYELGMALGIAMLGS
MUL_0838|M.ulcerans_Agy99 VVGFALDVVLVSANDAIISAVSEDYVGQAAGVEEVAYDLGGGLGIAVLGS
MAV_1387|M.avium_104 AMGVGMAFVWSPLTATATRNLSAQLAGAGSAVYNSVRQLGAVLGSAGMAA
TH_3965|M.thermoresistible__bu AVGVGMAFIWSPLATTATRQLPLHLSGAGSGVYNTTRQIGSVLGSAGMAA
MSMEG_5347|M.smegmatis_MC2_155 FVFGTLPLFWSIAMARMSG----LVAAASLAFINTIGLIGGFVGPYLFGL
MAB_0365c|M.abscessus_ATCC_199 FTFGFGSLVWVYAGESFPAR---LRSYGASAMLTSDLVANAVVSMYFLTL
. . .
Mb1699c|M.bovis_AF2122/97 LKDATGTYHLALL---TVAAVLAAAAACSLLLRHAGRTVCANDSEIMLHP
Rv1672c|M.tuberculosis_H37Rv LKDATGTYHLALL---TVAAVLAAAAACSLLLRHAGRTVCANDSEIMLHP
MMAR_0596|M.marinum_M LEQVTGTDKAGMW---AVGAMMLMSAFVVVLLRAVPGSPTAAE-----RP
Mflv_0241|M.gilvum_PYR-GCK ILTAVYRTVTIPA-GVPADAAAQARDSLPKAIDAARGLPDAAQS-ALLES
Mvan_0664|M.vanbaalenii_PYR-1 IVTAVYRTVVIAP-EIPSAAADLARDSLPGAIHAAHSLPADQQS-TLLDA
MUL_0838|M.ulcerans_Agy99 VLTATYTAAFDPISGLIDSQLATAQESIRTANDLADATSAPALASQIRIE
MAV_1387|M.avium_104 FMTWRIGAEMPGQ-----PGGGGEDSAGPVLPEFLRGPFAAAMSQSVLLP
TH_3965|M.thermoresistible__bu FLTGRLSAELPFG-----ATAVPAGEQTRVLPEFLHAPYAAAMAQSMLLP
MSMEG_5347|M.smegmatis_MC2_155 AETATHNPSAGFY--IVIVSSVIGVALAPVLAHAIRREDSTA--------
MAB_0365c|M.abscessus_ATCC_199 LTALGGVVAFGVFG----VLATAALVFVHVLAPETKGRNLEEIRHFWESG
Mb1699c|M.bovis_AF2122/97 SPATPFV-------------------------------------------
Rv1672c|M.tuberculosis_H37Rv SPATPFV-------------------------------------------
MMAR_0596|M.marinum_M N-------------------------------------------------
Mflv_0241|M.gilvum_PYR-GCK AKESFTLGLSVSAGVGAALLLTSA----------VAVWWLLR--SPGPAE
Mvan_0664|M.vanbaalenii_PYR-1 ARASFTHGLASASAAGAVLLLTAA----------VAVWWLLRPGSPGAAE
MUL_0838|M.ulcerans_Agy99 AHTAFLAGFHTTIVVAIAILAAAA----------VAAGALLS--------
MAV_1387|M.avium_104 AFIALFGIVAALFLVGFRPWAHRDGGTDAFGPDDYGGDYHDDYDDDDAYV
TH_3965|M.thermoresistible__bu AFVALFGVLAAIFLAGIVLSTPQP---------DADAQYLDEHDD---YL
MSMEG_5347|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0365c|M.abscessus_ATCC_199 GTWPET--------------------------------------------
Mb1699c|M.bovis_AF2122/97 --------------------------------------------------
Rv1672c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0596|M.marinum_M --------------------------------------------------
Mflv_0241|M.gilvum_PYR-GCK VGVLPD---------------PGVHHDARGDGGVDTAGGAELGNRHS---
Mvan_0664|M.vanbaalenii_PYR-1 VGVLAD---------------PGVHRDPGRDARVDAPGGAELGDRNS---
MUL_0838|M.ulcerans_Agy99 TKTLPE---------------PAGQDAPDPSA------------------
MAV_1387|M.avium_104 ELILVREPEPEAQQRAGQPRRPQPTPAPPADVRRRDPVESRRSVLDERPA
TH_3965|M.thermoresistible__bu VIELAR-----------------PDPNPRTDIAVTAVIPALRPTLRP---
MSMEG_5347|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0365c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1699c|M.bovis_AF2122/97 --------------------------------------------------
Rv1672c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0596|M.marinum_M --------------------------------------------------
Mflv_0241|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0664|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0838|M.ulcerans_Agy99 --------------------------------------------------
MAV_1387|M.avium_104 QVQPIGFAHNGSHVDGGKRLRQVAVRRAPKPGPPADRFTRPPRRHHPGPA
TH_3965|M.thermoresistible__bu -----------------------TLR--PSLGPPGGPVVQP---------
MSMEG_5347|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0365c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1699c|M.bovis_AF2122/97 ---------------------------------
Rv1672c|M.tuberculosis_H37Rv ---------------------------------
MMAR_0596|M.marinum_M ---------------------------------
Mflv_0241|M.gilvum_PYR-GCK ---------------------------------
Mvan_0664|M.vanbaalenii_PYR-1 ---------------------------------
MUL_0838|M.ulcerans_Agy99 ---------------------------------
MAV_1387|M.avium_104 GHHLGEGESLRGQHHRPDPDDDPTGYGRHSSGN
TH_3965|M.thermoresistible__bu ----NNTAALR----------------------
MSMEG_5347|M.smegmatis_MC2_155 ---------------------------------
MAB_0365c|M.abscessus_ATCC_199 ---------------------------------