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M. smegmatis MC2 155 MSMEG_5174 (-)

annotation: regulatory protein GntR, HTH
coordinates: 5274219 - 5274575
length: 118

GDWVSIDPDSDKPLFDQLRVQIIDGIRDGRLSPGTRLPTVRELATHVGLAVNTVARSYRELEAAGVLETR
GRFGTFVARADPADAAMAAAANSFAEAARSLGISRDDALRYIESALD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5174--100% (118)regulatory protein GntR, HTH
M. smegmatis MC2 155MSMEG_6371-2e-1050.00% (66) GntR-family protein regulator
M. smegmatis MC2 155MSMEG_4140-6e-1055.17% (58) GntR-family protein transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1183-1e-3961.02% (118) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_2135-2e-4876.72% (116) regulatory protein GntR, HTH
M. tuberculosis H37RvRv1152-1e-3961.02% (118) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0196c-5e-0953.70% (54) GntR family transcriptional regulator
M. marinum MMMAR_4301-2e-4061.86% (118) transcriptional regulatory protein
M. avium 104MAV_1290-4e-4366.95% (118) regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_3932-2e-0834.69% (98) PUTATIVE transcriptional regulator, GntR family
M. ulcerans Agy99MUL_0993-5e-3858.47% (118) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_4569-1e-4571.55% (116) regulatory protein GntR, HTH

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2135|M.gilvum_PYR-GCK          -----------MGDLGDWVKVDPHA-----ARPLFDQLRTQIIAGVRDGE
Mvan_4569|M.vanbaalenii_PYR-1       -----------MAELGDWVRVDPHA-----ARPLFDQLRTQIIAGIRDGE
MSMEG_5174|M.smegmatis_MC2_155      --------------MGDWVSIDPDS-----DKPLFDQLRVQIIDGIRDGR
MMAR_4301|M.marinum_M               ------------MELRDWLRVDVKA-----GKPLFDQLRTQVIDGVRAGA
MUL_0993|M.ulcerans_Agy99           ------------MELRDWLRVDVKA-----GKPLFDQLGTQVIDGVRAGA
Mb1183|M.bovis_AF2122/97            ------------MELRDWLRVDVKA-----GKPLFDQLRTQVIDGVRAGA
Rv1152|M.tuberculosis_H37Rv         ------------MELRDWLRVDVKA-----GKPLFDQLRTQVIDGVRAGA
MAV_1290|M.avium_104                ------------MELGDWLRVDMKA-----GKPLFDQLRTQVIEGVREGA
MAB_0196c|M.abscessus_ATCC_199      MSSWANSAKAESRPLSHDLHLDLRQSITPGTRGVRELLTSALRDAVRSGR
TH_3932|M.thermoresistible__bu      ----------MTRTATPMRSTTINR---FADRPLYRQLS-EVLEARLIER
                                                                   : :   *   :  .     

Mflv_2135|M.gilvum_PYR-GCK          LAPGTRLPTVRELAGQVNLAVNTVARAYRELEAAGILETRGRFGTFVAR-
Mvan_4569|M.vanbaalenii_PYR-1       LTPGTRLPTVRELAGQINLAVNTVARAYRELEAAGILETRGRFGTYVAR-
MSMEG_5174|M.smegmatis_MC2_155      LSPGTRLPTVRELATHVGLAVNTVARSYRELEAAGVLETRGRFGTFVAR-
MMAR_4301|M.marinum_M               LPPGTRLPTVRDLAGQLGVAANTVARAYRELESAAIVETRGRFGTFISR-
MUL_0993|M.ulcerans_Agy99           LPPGTRLPTVRDLVGQLGVAANTVARAYRELESVAIVETRGRCGTFISR-
Mb1183|M.bovis_AF2122/97            LPPGTRLPTVRDLAGQLGVAANTVARAYRELESAAIVETRGRFGTFISR-
Rv1152|M.tuberculosis_H37Rv         LPPGTRLPTVRDLAGQLGVAANTVARAYRELESAAIVETRGRFGTFISR-
MAV_1290|M.avium_104                LPPGTRLPTVRELAGQLGVAVNTVARAYRELESAAIIETRGRFGTFVAR-
MAB_0196c|M.abscessus_ATCC_199      LTVGSMLPPSRTLASDLGLARNTVAEAYAELVAEGWLESRQGSGTRVVNR
TH_3932|M.thermoresistible__bu      ARPGDRLPSEAELSGQFGVNRLTVRRALHELAQRGIIETVHGRGSFVAR-
                                       *  **.   *  ...:   ** .:  **   . :*:    *: : . 

Mflv_2135|M.gilvum_PYR-GCK          ---------------------ADPADVAMATAANTYVSAARALGVEKDEA
Mvan_4569|M.vanbaalenii_PYR-1       ---------------------SDPADAAMATAAHTYVATARALGVGKGEA
MSMEG_5174|M.smegmatis_MC2_155      ---------------------ADPADAAMAAAANSFAEAARSLGISRDDA
MMAR_4301|M.marinum_M               ---------------------FDPTDAAMAAAAKEYVEVARALGLTKSDA
MUL_0993|M.ulcerans_Agy99           ---------------------FDPTDAAMAAAAKEYVEVARALGLTKSDA
Mb1183|M.bovis_AF2122/97            ---------------------FDPTDAAMAAAAKEYVGVARALGLTKSDA
Rv1152|M.tuberculosis_H37Rv         ---------------------FDPTDAAMAAAAKEYVGVARALGLTKSDA
MAV_1290|M.avium_104                ---------------------YDPTDAAMAAAAREYVRVARGLGLDKADA
MAB_0196c|M.abscessus_ATCC_199      GKDQLPPRPRGAGTPPPHNLMPGSGDVTAFPRADWLASARRALNHAPHEA
TH_3932|M.thermoresistible__bu      ---------------------QPVRYRLSATRDASFTRGMRELGHPVRIE
                                                                  .     .   * *.      

Mflv_2135|M.gilvum_PYR-GCK          LRY----------------------IESAFG-------------------
Mvan_4569|M.vanbaalenii_PYR-1       LRY----------------------VETAFG-------------------
MSMEG_5174|M.smegmatis_MC2_155      LRY----------------------IESALD-------------------
MMAR_4301|M.marinum_M               IRY----------------------LTAVPDD------------------
MUL_0993|M.ulcerans_Agy99           IRY----------------------LTAVPDD------------------
Mb1183|M.bovis_AF2122/97            MRY----------------------LTHVPDD------------------
Rv1152|M.tuberculosis_H37Rv         MRY----------------------LTHVPDD------------------
MAV_1290|M.avium_104                VRY----------------------IESVPDE------------------
MAB_0196c|M.abscessus_ATCC_199      LRVGDPRGRHELRSAVAEYVSRVRGVRTTPDSILICAGTRHAVEILTRMY
TH_3932|M.thermoresistible__bu      VLG------------------AETTRCRRLRTELHTAGEVLTTTTLRHVD
                                    :                                                 

Mflv_2135|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4569|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5174|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_4301|M.marinum_M               --------------------------------------------------
MUL_0993|M.ulcerans_Agy99           --------------------------------------------------
Mb1183|M.bovis_AF2122/97            --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1290|M.avium_104                --------------------------------------------------
MAB_0196c|M.abscessus_ATCC_199      GLARPIAVEAYGLFIFRDCIEATGGSSTPIGFDGEGAVVSDLENLDTSAA
TH_3932|M.thermoresistible__bu      GQPWSVSVTSIALDRFPGIAQQWSGSTSLFDFLWQTFGVRMRRAYRSFSA
                                                                                      

Mflv_2135|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4569|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5174|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_4301|M.marinum_M               --------------------------------------------------
MUL_0993|M.ulcerans_Agy99           --------------------------------------------------
Mb1183|M.bovis_AF2122/97            --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1290|M.avium_104                --------------------------------------------------
MAB_0196c|M.abscessus_ATCC_199      LITPAHHFPHGLPLHPARRTAVVDWARRTDSYVLEDDYDGEFRYDRQPVG
TH_3932|M.thermoresistible__bu      VLADLAEAQHLG--------------LRTGAPVLEMRGLNVDQHGAPVAV
                                                                                      

Mflv_2135|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4569|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5174|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_4301|M.marinum_M               --------------------------------------------------
MUL_0993|M.ulcerans_Agy99           --------------------------------------------------
Mb1183|M.bovis_AF2122/97            --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1290|M.avium_104                --------------------------------------------------
MAB_0196c|M.abscessus_ATCC_199      ALQSLDPDRVVYLGSASKSLAPALRLGWMVLPPEQMDAAVAATGGAQWYV
TH_3932|M.thermoresistible__bu      VRHRFRGDRVELTVDLA---------------------------------
                                                                                      

Mflv_2135|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4569|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5174|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_4301|M.marinum_M               --------------------------------------------------
MUL_0993|M.ulcerans_Agy99           --------------------------------------------------
Mb1183|M.bovis_AF2122/97            --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1290|M.avium_104                --------------------------------------------------
MAB_0196c|M.abscessus_ATCC_199      GAISQLTMADFIAGGHYDRHIRRMRGRYRRRRDLLVQRLAGYNVGVRGLS
TH_3932|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_2135|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4569|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5174|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_4301|M.marinum_M               --------------------------------------------------
MUL_0993|M.ulcerans_Agy99           --------------------------------------------------
Mb1183|M.bovis_AF2122/97            --------------------------------------------------
Rv1152|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_1290|M.avium_104                --------------------------------------------------
MAB_0196c|M.abscessus_ATCC_199      AGLHLLLTLPEGTESDVLYRAGEAGVALAGLARLRHPLAGPHIPNPDGVV
TH_3932|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_2135|M.gilvum_PYR-GCK          ---------------------------
Mvan_4569|M.vanbaalenii_PYR-1       ---------------------------
MSMEG_5174|M.smegmatis_MC2_155      ---------------------------
MMAR_4301|M.marinum_M               ---------------------------
MUL_0993|M.ulcerans_Agy99           ---------------------------
Mb1183|M.bovis_AF2122/97            ---------------------------
Rv1152|M.tuberculosis_H37Rv         ---------------------------
MAV_1290|M.avium_104                ---------------------------
MAB_0196c|M.abscessus_ATCC_199      VSFGTPADHGFGPAVDALCRVLAATGL
TH_3932|M.thermoresistible__bu      ---------------------------