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MATIDGNTLEGISATTPWTLHHRASGAKRSNVVRFLAPLLAAIVTSAGCGALPTEVTETPAAAEVEVLPE VTVQRFEYAADSEQNWADLYLPAGPQQVDSIPLVVLIHGGAWQSKLGADVFDGLARELADHGMAVYNIEY RRVGSGGGWPTTFHDVATALDYVTEVDKRFPQLTVDDELVVGHSAGAQLAVWAGTRHKLRDDEVGSHPSF RPTRVVSLAGPLDMVYAAEHGDHHIVRVLGGRPTEVPDRYTSVDPIQNIDPEVPVLALHGTRDTVVSPEN SRRYVAAVKQQGGRAAVKMLTGENHTSIVSLRSPSHDEVLRAITTTSQTDLDDLLTE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5171 | - | - | 100% (337) | hypothetical protein MSMEG_5171 |
| M. smegmatis MC2 155 | MSMEG_0289 | - | 1e-08 | 27.80% (313) | alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_0302 | - | 2e-07 | 23.96% (217) | peptidase, S9A/B/C families |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2510c | lipQ | 6e-07 | 24.00% (225) | carboxylesterase LipQ |
| M. gilvum PYR-GCK | Mflv_0440 | - | 2e-08 | 27.00% (200) | alpha/beta hydrolase domain-containing protein |
| M. tuberculosis H37Rv | Rv2485c | lipQ | 6e-07 | 24.00% (225) | carboxylesterase LipQ |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3447c | - | 5e-22 | 35.81% (229) | putative lipase/esterase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4953 | - | 6e-07 | 25.81% (217) | alpha/beta hydrolase fold |
| M. thermoresistible (build 8) | TH_2755 | - | 7e-08 | 27.31% (227) | PUTATIVE Alpha/beta hydrolase fold-3 domain protein |
| M. ulcerans Agy99 | MUL_3766 | lipQ | 8e-05 | 24.88% (205) | carboxylesterase LipQ |
| M. vanbaalenii PYR-1 | Mvan_0227 | - | 6e-08 | 27.65% (217) | alpha/beta hydrolase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0440|M.gilvum_PYR-GCK --MTERPDTRYPGPTLTTRLEWLLNAGPSDYMLALSVASASLPVIGKHLE
Mvan_0227|M.vanbaalenii_PYR-1 --MTERPDIRYPGPTLTTRLQWLLNAGPSDFMLAMSVASASLPVIGKHLE
TH_2755|M.thermoresistible__bu --MTVRPDG---GSSAWLCARRLLRAGPADHLLALSAASGSLPIVGRHLE
MAV_4953|M.avium_104 -----------MAPGMTPYLKWLLRARPADYALAVSLAGASLPVVGRHLE
Mb2510c|M.bovis_AF2122/97 MHIASVTSRCSRAGAEALRQGAQLAADARDTCRAGALLLRGSPCAIGWVA
Rv2485c|M.tuberculosis_H37Rv MHIASVTSRCSRAGAEALRQGAQLAADARDTCRAGALLLRGSPCAIGWVA
MUL_3766|M.ulcerans_Agy99 MCMASVTSRCSRAGAEALRQGAQLAADARDAVRSGALLLRGSPFALGWVA
MAB_3447c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5171|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0440|M.gilvum_PYR-GCK PLGALTAAGVWGARHAPDFVGALAKSLVAPNDVGKKEKQQQERDSTNAIT
Mvan_0227|M.vanbaalenii_PYR-1 PLGALTAAGIWGTRHAPDFVGALAKSLITPNDAERK---KQERDCTNAVT
TH_2755|M.thermoresistible__bu PLGSAAAMSLWGFRHLPDFVGATVKSWLAPGSAELR---RRQREMTNEVS
MAV_4953|M.avium_104 PLAGLTAMGMWGARHAPEVISAATRDMFAPGGGDAR---RRDRESTQQVS
Mb2510c|M.bovis_AF2122/97 GWLSAEFPARVVTGHALSRISPRSIGRFGTSWAAQR-ADQILHAALVDAF
Rv2485c|M.tuberculosis_H37Rv GWLSAEFPARVVTGHALSRISPRSIGRFGTSWAAQR-ADQILHAALVDAF
MUL_3766|M.ulcerans_Agy99 GWVSAEFPPHVLTGHALSRVSPPAIGRYGTAWAAQR-ADLTLTAALEESF
MAB_3447c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5171|M.smegmatis_MC2_155 --------MATIDGNTLEGISATTPWTLHHRASGAK------RSNVVRFL
Mflv_0440|M.gilvum_PYR-GCK QAALRGLVSQK--------------DLEIEWPAAERTPPVWKMREHRRHV
Mvan_0227|M.vanbaalenii_PYR-1 EAALRDVVGPK--------------DLEIEWPAAERTPPVWRMREHRRHV
TH_2755|M.thermoresistible__bu RQALRGLLPADPAAPGASEVSSGSAGSALDWPAPDRVPPLWRMLQHRRHL
MAV_4953|M.avium_104 LAALRGLVSAA--------------ELESQWPVAQRTPPIWDGVRRHRHL
Mb2510c|M.bovis_AF2122/97 GPDFRDLVWHPTGE-----------QSEAARRSGLLNLPHIPGPHRRYAA
Rv2485c|M.tuberculosis_H37Rv GPDFRDLVWHPTGE-----------QSEAARRSGLLNLPHIPGPHRRYAA
MUL_3766|M.ulcerans_Agy99 GSQFRDLVSHPSGD-----------GSACATRGGLLPS----GPRRRYAA
MAB_3447c|M.abscessus_ATCC_199 ---------------------------------------MNLIQEGEAMP
MSMEG_5171|M.smegmatis_MC2_155 APLLAAIVTSAGCG---------------ALPTEVTETPAAAEVEVLPEV
.
Mflv_0440|M.gilvum_PYR-GCK HRTSVRYGPR-PTQLLDVWRR-DDVPAD-APVMIFVPGGAWVHGGRMLQG
Mvan_0227|M.vanbaalenii_PYR-1 HRTSVRYGPR-PTQLLDVWRR-DDLPAEPAPVLIFVPGGAWVHGSRMLQG
TH_2755|M.thermoresistible__bu YRGAVRYGDH-TENVLDVWRR-KDLPAQPAPVLIFVPGGAWVHGSRMLQG
MAV_4953|M.avium_104 YRRAVHYGHH-PAQVLDVWRR-KDLPAQPAPVLIFVPGGAWVHGKSMGQG
Mb2510c|M.bovis_AF2122/97 QTSDIPYGPGGRENLLDIWRRPDLAPGRRAPVLIQVPGGAWTINGKRPQA
Rv2485c|M.tuberculosis_H37Rv QTSDIPYGPGGRENLLDIWRRPDLAPGRRAPVLIQVPGGAWTINGKRPQA
MUL_3766|M.ulcerans_Agy99 QTSDISYGPGGREHLLDVWRRPDLAPGGRAPVLIQVPGGAWSVNGKRPQA
MAB_3447c|M.abscessus_ATCC_199 QHRRLTYGDH-PSQYVDILEP----DEPAAALVHVIHGGFWREALSAELT
MSMEG_5171|M.smegmatis_MC2_155 TVQRFEYAADSEQNWADLYLPAGPQQVDSIPLVVLIHGGAWQSKLGADVF
. *. : *: .:: : ** *
Mflv_0440|M.gilvum_PYR-GCK YALMHHLAEMGWVCLSVEYR-VAPHNPWPAHINDVKTAIAWARANVDKF-
Mvan_0227|M.vanbaalenii_PYR-1 YALMSHLAERGWVCLSIDYR-VAPHNPWPAHVADVKTAIAWARANVDKF-
TH_2755|M.thermoresistible__bu YALLSHLAEQGWVCLSIDYR-VAPQHPWPAHLTDVKTAIAWARANVDKF-
MAV_4953|M.avium_104 SALMSRLAEQGWVCLAIDYR-VAPHHRWPRHIVDVKTAIAWARANVDKF-
Mb2510c|M.bovis_AF2122/97 YPLMSRMVELGWICVSINYS-KSPRCTWPAHIVDVKRAIAWVRENIADY-
Rv2485c|M.tuberculosis_H37Rv YPLMSRMVELGWICVSINYS-KSPRCTWPAHIVDVKRAIAWVRENIADY-
MUL_3766|M.ulcerans_Agy99 YTLMSRMVELGWICVSINYS-KSPRCKFPAHVVDVKRAIAWVRENIAAY-
MAB_3447c|M.abscessus_ATCC_199 APIARDLCTDGFLVANIEYRRVGGGGGWPETFEDVKAAIAAVRQAEPDL-
MSMEG_5171|M.smegmatis_MC2_155 DGLARELADHGMAVYNIEYRRVGSGGGWPTTFHDVATALDYVTEVDKRFP
: : * ::* . :* . ** *: .
Mflv_0440|M.gilvum_PYR-GCK GGNRDFVAIAGTSAGGHLAALAGLTANDPEMQGELPEGSDTSVDAVVGIY
Mvan_0227|M.vanbaalenii_PYR-1 GGDRNFVAISGASAGGHLAALAGLTANDPEMQDELPEGSDTSVDAVVGIY
TH_2755|M.thermoresistible__bu GGDRDFVAVAGCSAGGHLAALAGLTENDPDMQTELPEGSDTSVDAVVGVY
MAV_4953|M.avium_104 GGDRNFVAIAGCSAGGHLSALAGLTPDDPQYRGMLPEGADTSVDAVVGIY
Mb2510c|M.bovis_AF2122/97 GGDPDFITITGGSAGAHLAALAALSANDPALQPGF-ESADTAVQAAAPYY
Rv2485c|M.tuberculosis_H37Rv GGDPDFITITGGSAGAHLAALAALSANDPALQPGF-ESADTAVQAAAPYY
MUL_3766|M.ulcerans_Agy99 GGNPDFIALTGGSAGAHLASLAALTPCDPAFQPGF-EHADTTVQAVAPYY
MAB_3447c|M.abscessus_ATCC_199 VRS----LAVGHSAGGHLSLLA-LAAGLADFAVALAPVSDVDRALRENLG
MSMEG_5171|M.smegmatis_MC2_155 QLTVDDELVVGHSAGAQLAVWAGTRHKLR--DDEVGSHPSFRPTRVVSLA
* ***.:*: * . ..
Mflv_0440|M.gilvum_PYR-GCK GRYDWEDKSTVERVRFMDFLERVVVKRKFDKHPDVFRKASPMARIHSEAP
Mvan_0227|M.vanbaalenii_PYR-1 GRYDWEDKSTVERVRFMDFLERVVVRRKFDRHPELFRKASPMARVHPEAP
TH_2755|M.thermoresistible__bu GRYDWVDRSTAERVRFLDFLERVVVRKRLDRHPEVFHRASPMHRVHGDAP
MAV_4953|M.avium_104 GRYDWEDRSTPERVRFVDFLERVVVRKSIARHPEVFRDASPIARVHRNAP
Mb2510c|M.bovis_AF2122/97 GVYDLTN-AENMHEMMMPFLEHFVMRSRYVDNPGLFKAASPISYVHSEAP
Rv2485c|M.tuberculosis_H37Rv GVYDLTN-AENMHEMMMPFLEHFVMRSRYVDNPGLFKAASPISYVHSEAP
MUL_3766|M.ulcerans_Agy99 GVYDFTD-FDNMHELMLPFLEHFVMKSRYADDPEPFTAASPISYVHREAP
MAB_3447c|M.abscessus_ATCC_199 G------------GAAAEFLG------VAGSSPREVRTASPIGNLG-HRR
MSMEG_5171|M.smegmatis_MC2_155 GPLDMVYAAEHGDHHIVRVLG-----GRPTEVPDRYTSVDPIQNIDPEVP
* .* * ..*: : .
Mflv_0440|M.gilvum_PYR-GCK PFLVIHGTGDSVIPVAQAQSFVERLRNVSRSVVGYVELPGAGHGFDMTDG
Mvan_0227|M.vanbaalenii_PYR-1 PFLVVHGTGDSVIPVAQAQSFVERLRGVSRSVVGYVELPGAGHGFDMTDG
TH_2755|M.thermoresistible__bu PFLLVHGSADTVIPVRQARDFADRLRSVSRSAVSYLELPGAGHGFDLLDG
MAV_4953|M.avium_104 PFLVIHGSKDSVIPVEQARSFVERLRAVSHSTVGYLELPGAGHGYDLIDG
Mb2510c|M.bovis_AF2122/97 PFFVLHGEKDPMVPSAQSRAFSAALRDAGAATVSYAELPNAHHAFDLAAT
Rv2485c|M.tuberculosis_H37Rv PFFVLHGEKDPMVPSAQSRAFSAALRDAGAATVSYAELPNAHHAFDLAAT
MUL_3766|M.ulcerans_Agy99 PFFVLHGERDELVPSGQARAFCAALRGAGADTVAYAELANAHHAFDITPT
MAB_3447c|M.abscessus_ATCC_199 QHVLIHGLRDVNVPVEHSQHYVSAAR-ASGTPVDYFEFANLDH-FDLIDP
MSMEG_5171|M.smegmatis_MC2_155 -VLALHGTRDTVVSPENSRRYVAAVKQQGGRAAVKMLTGENHTSIVSLRS
. :** * :. ::: : : . .
Mflv_0440|M.gilvum_PYR-GCK ARTGAAATAIGLFLNHIHRNRSLVGAKEVI-------
Mvan_0227|M.vanbaalenii_PYR-1 ARTGAASTAIGLFLNHIHRNRTLIGAKEVI-------
TH_2755|M.thermoresistible__bu ARTGSAATAVGLFLDHVQRNRSRVRGRAVG-------
MAV_4953|M.avium_104 ERAGAAAHVCSLFLDQVHRSKTRIGAKEVI-------
Mb2510c|M.bovis_AF2122/97 VRSRMVAEAVSDFLGVIYGRRMGARKGSLALSSPPAS
Rv2485c|M.tuberculosis_H37Rv VRSRMVAEAVSDFLGVIYGRRMGARKGSLALSSPPAS
MUL_3766|M.ulcerans_Agy99 VRSRLAASAVSDFLGVVYGRWTSSVLGSLAFSANSAS
MAB_3447c|M.abscessus_ATCC_199 SSSAWRVAKQWIRYQLI--------------------
MSMEG_5171|M.smegmatis_MC2_155 PSHDEVLRAITTTSQTDLDDLLTE-------------