For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NIVLVHGAFVDGSTWRVVYDLLVDEGHRVVVVQTPNLSLSGDVEATRRVLDSLVGSVVLVGHSCGGAVIT EAGNHDSVSALVYIAAFVPDEGESVESLGGHPGVQGSPIVPFSGGFLLQDRAKFHSSFGADLPTADAAFL ADSQIPWSTEAMTSPVTDPAWRRRPCWYLIATEDRMIPLAAQRVMAQRAGAATVEVAASHAVYMSQPRAV AALIGQAVHV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5107 | - | - | 100% (221) | secreted protein |
| M. smegmatis MC2 155 | MSMEG_6658 | - | 4e-29 | 38.67% (225) | alpha/beta hydrolase fold |
| M. smegmatis MC2 155 | MSMEG_1797 | - | 4e-09 | 24.89% (233) | salicylate esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2476 | - | 4e-10 | 28.17% (252) | esterase EstC, putative |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0768 | - | 1e-37 | 42.92% (219) | hypothetical protein MAB_0768 |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_1840 | - | 7e-05 | 27.13% (247) | hydrolase, alpha/beta fold family protein, putative |
| M. thermoresistible (build 8) | TH_2893 | - | 1e-19 | 31.11% (225) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1601 | - | 6e-48 | 46.33% (218) | hypothetical protein Mvan_1601 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2893|M.thermoresistible__bu ---------------------------------MAKPILLVHGAFSGSWV
MAB_0768|M.abscessus_ATCC_1997 ---------------------------MSSKP----TIVLVHGFWGGAAH
Mvan_1601|M.vanbaalenii_PYR-1 MNRQIRSLVVAAAAAAAILATVAPGGSAHAQPAEVKNVVLVHGAFADGSG
MSMEG_5107|M.smegmatis_MC2_155 -----------------------------------MNIVLVHGAFVDGST
Mflv_2476|M.gilvum_PYR-GCK -----------------------------------MRFILVHGGFHAAWC
MAV_1840|M.avium_104 ----------------MASIAVGDVEIDYVDAGSGPVVVFVHGAYVTGLL
.::*** : .
TH_2893|M.thermoresistible__bu WDQVVAELASCGVQARTVELSSR-------KPDGTLARDAHVVRDALKQF
MAB_0768|M.abscessus_ATCC_1997 WGNVIVELHGRGFEDLHAVEN----------PLTSLADDAARTRQMVQQI
Mvan_1601|M.vanbaalenii_PYR-1 WRGVYDELTARGYR-VTIVQN----------PLTSLADDVAATKRVLDQQ
MSMEG_5107|M.smegmatis_MC2_155 WRVVYDLLVDEGHR-VVVVQT----------PNLSLSGDVEATRRVLDSL
Mflv_2476|M.gilvum_PYR-GCK WERTAAALRALGHDVTAVDLPGHGAL---ADQESTLANRRDAIVAAMQAG
MAV_1840|M.avium_104 WQDVVDRLSDSHRCIAPTLPFGAQAAPVGAHVDLSVAASGRLIAGLLDAL
* . * ::: :.
TH_2893|M.thermoresistible__bu DQ-PAVLVGHSYGG-----AVITEASADNDHVAHLIYVCA-----ALPQA
MAB_0768|M.abscessus_ATCC_1997 DG-PVLLVGHSYGG-----AVITEAG-DLPNVAGLVYVAA-----FAPDA
Mvan_1601|M.vanbaalenii_PYR-1 DG-PTLLVGHSYGG-----TVITEAG-VDPKVTGLVYVSG-----LAPDA
MSMEG_5107|M.smegmatis_MC2_155 VG-SVVLVGHSCGG-----AVITEAG-NHDSVSALVYIAA-----FVPDE
Mflv_2476|M.gilvum_PYR-GCK DE-KCVLVGHSGGG----FDATLAADARPDLVSHITYLAA-----ALPRE
MAV_1840|M.avium_104 DLSDVTLVANDTGGGIVL-AALGNASLKWDRVSKLVFTNCDSFEHFPPKS
**.:. ** . *. *: : : *
TH_2893|M.thermoresistible__bu GESVSDVLARDPDPQGDLAPALEVR--------------EDGTATMKRDA
MAB_0768|M.abscessus_ATCC_1997 GESPGQLTEQLPPAAA---ANLVPD--------------SDGYLWIKQDK
Mvan_1601|M.vanbaalenii_PYR-1 GETTSQQYADYPTPPS---FVIETG--------------PDGFGFINREK
MSMEG_5107|M.smegmatis_MC2_155 GES-VESLGGHPGVQG---SPIVPF--------------SGGFLLQDRAK
Mflv_2476|M.gilvum_PYR-GCK GRTYPEAMAMRDDDNGPVELGEDFDGDVGEMLGYLHFDDTGAMKFADFDG
MAV_1840|M.avium_104 FAPIVRLCALSQSLGAIALKGLTTAPG------LKVFTSAVTLNGVDAAR
. . .
TH_2893|M.thermoresistible__bu ARQALFNDATEEQFESVVDKLGP-HAMGTLSEPVTGLGWQQH--PATYVI
MAB_0768|M.abscessus_ATCC_1997 FRESFAQDLPEDAALVMAVTQKA-PLASTFGDAITAPAWRNK--PSWYQV
Mvan_1601|M.vanbaalenii_PYR-1 FKAGFAADTSDEVAAFLRDSQVP-INMAIFGDTLTQAAWRTK--PSWAVV
MSMEG_5107|M.smegmatis_MC2_155 FHSSFGADLPTADAAFLADSQIP-WSTEAMTSPVTDPAWRRR--PCWYLI
Mflv_2476|M.gilvum_PYR-GCK AWKYFYHDCDEETARWAFERLGPERFGDTTVTPVSVPNFWAADLPRSFIV
MAV_1840|M.avium_104 RRAVFGGFLTSPAVRREAARFTADLKPSHTLAAVDALKRWDR--PVLMAW
: . .: *
TH_2893|M.thermoresistible__bu ALRDQMFSVALQEEFASHVG--TVAKIDTG-HGPMATRPAELAEIIATAA
MAB_0768|M.abscessus_ATCC_1997 STQDRMINPENERRMAQRIKPRKTIELDAS-HASLASQPVAIADLIAEAA
Mvan_1601|M.vanbaalenii_PYR-1 ATQDEAIDPRMLRQMAQRIG-AQITDVEGS-HVVFLTNPRAVADVIDRAA
MSMEG_5107|M.smegmatis_MC2_155 ATEDRMIPLAAQRVMAQRAG-AATVEVAAS-HAVYMSQPRAVAALIGQAV
Mflv_2476|M.gilvum_PYR-GCK CEQDQAMPRWLADTVARRLG-VDQLTIDAS-HSPFLSRPREFADLLVHAT
MAV_1840|M.avium_104 GTSDKMFPLSHAERLAETFPNAVVRAIDNSSTYVMLDRPDETAQAIRAFV
*. : .* : . .* * : .
TH_2893|M.thermoresistible__bu R----------
MAB_0768|M.abscessus_ATCC_1997 GDIA-------
Mvan_1601|M.vanbaalenii_PYR-1 KESGRA-----
MSMEG_5107|M.smegmatis_MC2_155 HV---------
Mflv_2476|M.gilvum_PYR-GCK TTTPVAPLRPL
MAV_1840|M.avium_104 DPMKDVTR---