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NAAIRPVISAIAMLTVAAGVAVVALLGDDARSVAAPAPGAKPTIVLVHGAWADTSSWDGELTVLRGQGYD ARAIANPLRNLTTDAASVASFLHTVDGPVVLVGHSYGGAVITEAAAGNPDIKALVYVDAAAPDVGETNGS LSGADSVLKKLPDHQLFDQVAGPVGETDLYLRRDIFVNHFAKDLPQDQATELWATQRTAATAAFDTPATQ AAWKDIPSWYFISTGDEIITPTAEHAMAQRAHSAVTEFPGGSHLTLVSHPDAVTDVILAAARSVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6658 | - | - | 100% (276) | alpha/beta hydrolase fold |
| M. smegmatis MC2 155 | MSMEG_5107 | - | 5e-29 | 38.67% (225) | secreted protein |
| M. smegmatis MC2 155 | MSMEG_5763 | - | 4e-15 | 26.52% (230) | hypothetical protein MSMEG_5763 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3622c | - | 7e-06 | 27.54% (236) | putative hydrolase |
| M. gilvum PYR-GCK | Mflv_2476 | - | 9e-09 | 25.88% (255) | esterase EstC, putative |
| M. tuberculosis H37Rv | Rv3591c | - | 7e-06 | 27.54% (236) | hydrolase |
| M. leprae Br4923 | MLBr_01921 | - | 0.0001 | 31.48% (108) | hypothetical protein MLBr_01921 |
| M. abscessus ATCC 19977 | MAB_0768 | - | 1e-44 | 41.95% (236) | hypothetical protein MAB_0768 |
| M. marinum M | MMAR_1355 | lipV | 2e-06 | 28.33% (120) | lipase LipV |
| M. avium 104 | MAV_4984 | - | 3e-07 | 26.52% (132) | alpha/beta hydrolase fold-1 |
| M. thermoresistible (build 8) | TH_2893 | - | 3e-21 | 31.93% (238) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2524 | lipV | 2e-06 | 28.33% (120) | lipase LipV |
| M. vanbaalenii PYR-1 | Mvan_1601 | - | 2e-38 | 39.19% (273) | hypothetical protein Mvan_1601 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6658|M.smegmatis_MC2_155 MNAAIRPVISAIAMLTVAAGVAVVALLGDDARSVAAPAPGAKPTIVLVHG
MAB_0768|M.abscessus_ATCC_1997 --------------------------------------MSSKPTIVLVHG
Mvan_1601|M.vanbaalenii_PYR-1 MNRQIR-------SLVVAAAAAAAILATVAPGGSAHAQPAEVKNVVLVHG
TH_2893|M.thermoresistible__bu ----------------------------------------MAKPILLVHG
MMAR_1355|M.marinum_M ---------------------------MSTDLHVHRYGPEEPVRVLTIHG
MUL_2524|M.ulcerans_Agy99 ---------------------------MSTDLHVHRYGPEEPVRVLTIHG
Mb3622c|M.bovis_AF2122/97 --------------------------MPRMPANLLTHRGGRGEPLVLVHG
Rv3591c|M.tuberculosis_H37Rv --------------------------MPRMPANLLTHRGGRGEPLVLVHG
MLBr_01921|M.leprae_Br4923 -----------------------------MSTNLLTLRGGRGKPLILVHG
Mflv_2476|M.gilvum_PYR-GCK ------------------------------------------MRFILVHG
MAV_4984|M.avium_104 ----------------------MATVVSPDGTVIGYESVGAGPPLLLVHG
.: :**
MSMEG_6658|M.smegmatis_MC2_155 AWADTSSWDGELTVLRGQGY-DARAIAN-------PLRNLTTD--AASVA
MAB_0768|M.abscessus_ATCC_1997 FWGGAAHWGNVIVELHGRGFEDLHAVEN-------PLTSLADD--AARTR
Mvan_1601|M.vanbaalenii_PYR-1 AFADGSGWRGVYDELTARGY-RVTIVQN-------PLTSLADD--VAATK
TH_2893|M.thermoresistible__bu AFSGSWVWDQVVAELASCGVQARTVELSSRK----PDGTLARD--AHVVR
MMAR_1355|M.marinum_M VTEHGQSWEYLAGYLPEVSIAAPDLLGHGRSSWAAPWSIDANV--SALAA
MUL_2524|M.ulcerans_Agy99 VTEHGQSWEYLAGYLPEVNIAAPDLLGHGRSSWAAPWSIDANV--SALAA
Mb3622c|M.bovis_AF2122/97 LMGRGSTWARQLPWLTLLGAVYTYDAPWHRGRDVADPHPISTERFVADLG
Rv3591c|M.tuberculosis_H37Rv LMGRGSTWARQLPWLTLLGAVYTYDAPWHRGRDVADPHPISTERFVADLG
MLBr_01921|M.leprae_Br4923 LMGRGNTWSRQLPWLSQLGTVYTYDAPWHRGRNVVDPYPISTERFVTDLA
Mflv_2476|M.gilvum_PYR-GCK GFHAAWCWERTAAALRALGHDVTAVDLPGHGALADQESTLANR--RDAIV
MAV_4984|M.avium_104 STGTRARWRPVTPELA-RRYTVHAMDRRGRGLSTAEAEPYSLGREAEDVA
* * :
MSMEG_6658|M.smegmatis_MC2_155 SFLHTVDGPVVLVGHSYGGAVITEAAAGNPDIKA-LVYVDAAAPDVGETN
MAB_0768|M.abscessus_ATCC_1997 QMVQQIDGPVLLVGHSYGGAVITEAGD-LPNVAG-LVYVAAFAPDAGESP
Mvan_1601|M.vanbaalenii_PYR-1 RVLDQQDGPTLLVGHSYGGTVITEAGV-DPKVTG-LVYVSGLAPDAGETT
TH_2893|M.thermoresistible__bu DALKQFDQPAVLVGHSYGGAVITEASADNDHVAH-LIYVCAALPQAGESV
MMAR_1355|M.marinum_M LLKDQADGPVVVVGHSFGGAVALQLAAAHPDLVAALILLDPAIGLNGSRV
MUL_2524|M.ulcerans_Agy99 LLKDQADGPVVVVGHSFGGAVALQLAAAHPDLVAALILLDPAIGLDGSRV
Mb3622c|M.bovis_AF2122/97 DAVSALGAPTRMVGHSMGALHSWCLAAERPELVSALVVEDMAPDFRGRTT
Rv3591c|M.tuberculosis_H37Rv DAVSALGAPTRMVGHSMGALHSWCLAAERPELVSALVVEDMAPDFRGRTT
MLBr_01921|M.leprae_Br4923 DAVSTLGVPARLVGHSMGAMHSWCLAAERPDLVSALVVEDMAPDFRGCST
Mflv_2476|M.gilvum_PYR-GCK AAMQAGDEKCVLVGHSGGGFDATLAADARPDLVSHITYLAAALPREGRTY
MAV_4984|M.avium_104 AVAEAVGGDVYVVGHSYGALAVLDAAPITRAFRR-IVLYEPPIPSLGLDV
. :**** *. . . : *
MSMEG_6658|M.smegmatis_MC2_155 GSLSGA-------DSVLKKLPD--HQLFDQVAGPVGETDLYLRRDIFVNH
MAB_0768|M.abscessus_ATCC_1997 GQLT-------------EQLPP--AAAANLVPD--SDGYLWIKQDKFRES
Mvan_1601|M.vanbaalenii_PYR-1 SQQY-------------ADYPT--PPSFVIETG--PDGFGFINREKFKAG
TH_2893|M.thermoresistible__bu SDVLA------------RDPDP--QGDLAPALEVREDGTATMKRDAARQA
MMAR_1355|M.marinum_M REVVDA-------MVAFPDYTDPAEARMERAYGAWADVDPAVLDAELDEH
MUL_2524|M.ulcerans_Agy99 REVVDA-------MVAFPDYTDPAEARMERAYGAWADVDPAVLDAELDEH
Mb3622c|M.bovis_AF2122/97 GPWEP--------------WLRALPVEFDSAEQVFAEFGPVAGR-YFLDA
Rv3591c|M.tuberculosis_H37Rv GPWEP--------------WLRALPVEFDSAEQVFAEFGPVAGR-YFLDA
MLBr_01921|M.leprae_Br4923 GPWEP--------------WLRGIPVEFDSVEKVFDEFGPVAGQ-YFLDA
Mflv_2476|M.gilvum_PYR-GCK PEAMAMRDDDNGPVELGEDFDGDVGEMLGYLHFDDTGAMKFADFDGAWKY
MAV_4984|M.avium_104 GSPGG--------------WARITALSDPRDILEAFYRETLQLSESAIKD
MSMEG_6658|M.smegmatis_MC2_155 FAKDLPQDQATELWATQRTAATAAFD-TPATQA--AWKDIPSWYFISTGD
MAB_0768|M.abscessus_ATCC_1997 FAQDLPEDAALVMAVTQKAPLASTFG-DAITAP--AWRNKPSWYQVSTQD
Mvan_1601|M.vanbaalenii_PYR-1 FAADTSDEVAAFLRDSQVPINMAIFG-DTLTQA--AWRTKPSWAVVATQD
TH_2893|M.thermoresistible__bu LFNDATEEQFESVVDKLGPHAMGTLS-EPVTGL--GWQQHPATYVIALRD
MMAR_1355|M.marinum_M LITLPNGRYSWRISLPAMVCYWSELARDAALPP--PGIATTLVRAVRADP
MUL_2524|M.ulcerans_Agy99 LITLPNGRYSWRISLPAMVCYWSELARDAALPP--PGIATTLVRAVRADP
Mb3622c|M.bovis_AF2122/97 FDRTATG-WRLHGRTARWIEIAAEWGTRDYWAQ--WRAVRSPALLIEAGD
Rv3591c|M.tuberculosis_H37Rv FDRTATG-WRLHGRTARWIEIAAEWGTRDYWAQ--WRAVRSPALLIEAGD
MLBr_01921|M.leprae_Br4923 FDRTSTG-WQLHGHTSRWIEIAAEWGTRDYWEH--WLAVRSPVLLIEAGT
Mflv_2476|M.gilvum_PYR-GCK FYHDCDEETARWAFERLGPERFGDTTVTPVSVPNFWAADLPRSFIVCEQD
MAV_4984|M.avium_104 LANREFPYLAGSIRHTAGRELAQTRAYRLTERH--ANITTPVRMLLGTES
: . :
MSMEG_6658|M.smegmatis_MC2_155 EIITPTAEHAMAQRAHS-AVTEFPGGSHLTLVSHPDAVTDVILAAARSVR
MAB_0768|M.abscessus_ATCC_1997 RMINPENERRMAQRIKP-RKTIELDASHASLASQPVAIADLIAEAAGDIA
Mvan_1601|M.vanbaalenii_PYR-1 EAIDPRMLRQMAQRIGA-QITDVEG-SHVVFLTNPRAVADVIDRAAKESG
TH_2893|M.thermoresistible__bu QMFSVALQEEFASHVGT-VAKIDTG--HGPMATRPAELAEIIATAAR---
MMAR_1355|M.marinum_M QYVSDELIAALRERLGADFALREFECGHMVPQAKPTEVATLIREQLKTP-
MUL_2524|M.ulcerans_Agy99 QYVSDELIAALRERLGADFALREFECGHMVPQAKPTEVATLIREQLKTP-
Mb3622c|M.bovis_AF2122/97 GVTPPGQMRAMAERDYPTAYLRVPDAGHLVHDEAPQVYRRAVESFLAGLT
Rv3591c|M.tuberculosis_H37Rv GVTPPGQMRAMAERDYPTAYLRVPDAGHLVHDEAPQVYRRAVESFLAGLT
MLBr_01921|M.leprae_Br4923 SVTPHGQMLAMTKTACRTTYLYVPEAGHLIHDEATQVYRQAVVSFLAGCA
Mflv_2476|M.gilvum_PYR-GCK QAMPRWLADTVARRLGVDQLTIDAS--HSPFLSRPREFADLLVHATTTTP
MAV_4984|M.avium_104 PAYLRAATAVLAAKIPGATIVALHGQGHQAIDYDPDQFARAVLEFDSEEV
. * . :
MSMEG_6658|M.smegmatis_MC2_155 ----------
MAB_0768|M.abscessus_ATCC_1997 ----------
Mvan_1601|M.vanbaalenii_PYR-1 RA--------
TH_2893|M.thermoresistible__bu ----------
MMAR_1355|M.marinum_M ----------
MUL_2524|M.ulcerans_Agy99 ----------
Mb3622c|M.bovis_AF2122/97 P---------
Rv3591c|M.tuberculosis_H37Rv P---------
MLBr_01921|M.leprae_Br4923 GRD-------
Mflv_2476|M.gilvum_PYR-GCK VAPLRPL---
MAV_4984|M.avium_104 DSGGVGAVTA