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VVRPWIVWTTGLLAYIIAVLDRTTLGVSGLQAADRFSATPTVLSTFVVLQVVVYAGAQVPAGVLLDRFGS RVLIVCGAALMAGGQLVLAFSESLPAAIGARAIVGLGDAVTFISVLRLVPHWFKPSQVPLLTQLTGICGQ LGQVLSAVPFLALLTAAGWTPAYLSVGAFGLLVMALVLAVVKNTPHGRVVATETTSVRDIPGSVKTVWLR PGNRLGFFTHMGTQFSVTVFALMWGVPYLTVAQGLSTAAAGALLTVSVVTAISAGVAIGIFTGRHPHRRS RLVLWIIASNASIWTIVLALPGPAPTWLLVVLIVIISVGGPGSMVGFDFARTFNPSATLGTAQGMVNMGG FLASLIVMQAMGVVLSHAGSYSFESFRLAWTVQYAIWILATIGILITRHKTRRLMAAEQERMLLEGFEAH PPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4767 | - | - | 100% (423) | major facilitator superfamily protein permease |
| M. smegmatis MC2 155 | MSMEG_0705 | - | 4e-14 | 24.54% (432) | putative permease of the major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_2549 | - | 3e-12 | 19.39% (392) | major facilitator superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1766c | narK2 | 7e-09 | 22.86% (350) | nitrate/nitrite transporter NarK2 |
| M. gilvum PYR-GCK | Mflv_2530 | - | 1e-174 | 72.42% (417) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1737c | narK2 | 7e-09 | 22.86% (350) | nitrate/nitrite transporter NarK2 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3302 | - | 1e-11 | 25.52% (337) | major facilitator transporter |
| M. marinum M | MMAR_5094 | - | 6e-12 | 30.11% (186) | integral membrane transport protein |
| M. avium 104 | MAV_3846 | - | 1e-06 | 26.35% (296) | sugar transporter family protein |
| M. thermoresistible (build 8) | TH_0390 | - | 0.0 | 79.15% (422) | major facilitator superfamily protein permease |
| M. ulcerans Agy99 | MUL_4170 | - | 4e-12 | 30.11% (186) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_4127 | - | 0.0 | 75.90% (415) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1766c|M.bovis_AF2122/97 -----------------------------------------MRGQAANLV
Rv1737c|M.tuberculosis_H37Rv -----------------------------------------MRGQAANLV
MSMEG_4767|M.smegmatis_MC2_155 -----------------------------------------MVRPWIVWT
TH_0390|M.thermoresistible__bu -----------------------MNPGRRARTAAGDDDERLAVRPWIVWA
Mflv_2530|M.gilvum_PYR-GCK ------------MAHAQGRAPPWVGCFSRTLRQIRPMGRCLRVRPWIVWA
Mvan_4127|M.vanbaalenii_PYR-1 ------------------------------------------MRPWIVWA
MAB_3302|M.abscessus_ATCC_1997 ------------------------------MVTMVHVDEVGTARRWAMLA
MAV_3846|M.avium_104 MAGRRPQAPMTGNGTRPTPKYPGGMQAWGMQTDPVATPDVGAGTRWSIMV
MMAR_5094|M.marinum_M -------------------MRPFRGAVPDEVSGIRVSMNRGNVRPKLVLG
MUL_4170|M.ulcerans_Agy99 -------------------------------------MNRGNVRPKLVLG
Mb1766c|M.bovis_AF2122/97 LATWISVVNFWAWNLIGPLSTSYARDMSLSSAEASLLVATPILVGALGRI
Rv1737c|M.tuberculosis_H37Rv LATWISVVNFWAWNLIGPLSTSYARDMSLSSAEASLLVATPILVGALGRI
MSMEG_4767|M.smegmatis_MC2_155 TGLLAYIIAVLDRTTLGVSGLQAADRFSATPTVLSTFVVLQVVVYAGAQV
TH_0390|M.thermoresistible__bu TGLLAYIVAVLDRTTLGVSGLAAADRFNAAPAALSTFVVLQVIVYALAQV
Mflv_2530|M.gilvum_PYR-GCK TGVLAYMVAVFDRTTLGVSGLAAAERFTAGPTLLSMFVVLQVVVYAAAQV
Mvan_4127|M.vanbaalenii_PYR-1 TGLLAYIVAVLDRTTLGVSGLAAADRFGAGPSLLSTFVVLQVVVYAGAQV
MAB_3302|M.abscessus_ATCC_1997 IALGSTAGANVFINGVAFLIPALHAERGLDLANAGLLSAMPSFGMVLTLI
MAV_3846|M.avium_104 VSLLATASSFLFINGVAFLIPSLQGARGIRLDEAGLLASMPSWGMVVTLV
MMAR_5094|M.marinum_M VIVLGSFIASIDLTIVNVALPTLSRALQASNAELQWIVDSYAIAAAGLLL
MUL_4170|M.ulcerans_Agy99 VIVLGSFIASIDLTIVNVALPTLSRALQASNAELQWIVDSYAIAAAGLLL
. : : . :
Mb1766c|M.bovis_AF2122/97 VTGPLTDRFGGRAMLIAVTLASILPVLAVGVAATMGSYALLVFFGLFLGV
Rv1737c|M.tuberculosis_H37Rv VTGPLTDRFGGRAMLIAVTLASILPVLAVGVAATMGSYALLVFFGLFLGV
MSMEG_4767|M.smegmatis_MC2_155 PAGVLLDRFGSRVLIVCGAALMAGGQLVLAFSESLP-AAIGARAIVGLGD
TH_0390|M.thermoresistible__bu PAGLLLDRFGSKALIVAGAAVMATGQLILAFTESLT-LAILARAIVGLGD
Mflv_2530|M.gilvum_PYR-GCK PAGLLLDRYGSRALIVSGAALMASGQLVLAFTDSLP-VAVAGRAVVGLGD
Mvan_4127|M.vanbaalenii_PYR-1 PAGLLLDRYGSRALIASGAALMASGQLGLAFTESLP-AAIAARAVVGLGD
MAB_3302|M.abscessus_ATCC_1997 AWGALIDKFGERIALVSGLALT--AVAAFAAAESPSLTVTGAFLLLGGAA
MAV_3846|M.avium_104 AWGYVLDRVGERVVMTTGSALT--ALAAYAASSAHSMVLIAVYLFLGGMA
MMAR_5094|M.marinum_M AAGNLGDRYGRRGWLTIGLVIVG-ASSAVAASAGSAQAVIGARAVMGVGA
MUL_4170|M.ulcerans_Agy99 AAGNLGDRYGRRGWLTIGLVIVG-ASSAVAASAGSAQAVIGARAVMGVGA
* : *: * : : . : :
Mb1766c|M.bovis_AF2122/97 AGTIFAVGIPFANNWYQPARRGFSTGVFGMG-MVGTALSAFFTPRFVRWF
Rv1737c|M.tuberculosis_H37Rv AGTIFAVGIPFANNWYQPARRGFSTGVFGMG-MVGTALSAFFTPRFVRWF
MSMEG_4767|M.smegmatis_MC2_155 AVTFISV-LRLVPHWFKPSQVPLLTQLTGICGQLGQVLSAVPFLALLTAA
TH_0390|M.thermoresistible__bu AVTFISV-LRLVPHWFRPRQVPLVTQLTGICGQLGQVLSAVLFLALLTAR
Mflv_2530|M.gilvum_PYR-GCK AFTFISV-LRLVPHWFAPRQIPVVTQLTGIVGQLGQVLSAVPFLALLSAQ
Mvan_4127|M.vanbaalenii_PYR-1 AVTFISV-LRLVPHWFAPRQIPVVTQLTGICGQLGQVLSAIPFLALLSAS
MAB_3302|M.abscessus_ATCC_1997 AAACNSASGRVVVGWFPPHQRGTVMGIRQMAQPLGVAAGALVIPRIAEGH
MAV_3846|M.avium_104 AASCNTAGGRLVSAWFPPHQRGLAMGIRQTAQPLGIALGAMVIPELAE-H
MMAR_5094|M.marinum_M AIIFPTSLALVTNVFVDSTHRARAIGVWSAVTGIAVVIGPILGGWLIEHF
MUL_4170|M.ulcerans_Agy99 AIIFPTSLALVTNVFVDSTHRARAIGVWSAVTGIAVVIGPILGGWLIEHF
* : .. : . : : :. . ... :
Mb1766c|M.bovis_AF2122/97 GLFTTHAIVAAALASTAVVAMVVLRDAPYFRPNADPVLP-----------
Rv1737c|M.tuberculosis_H37Rv GLFTTHAIVAAALASTAVVAMVVLRDAPYFRPNADPVLP-----------
MSMEG_4767|M.smegmatis_MC2_155 GWTPAYLSVGAFGLLVMALVLAVVKNTPHGRVVATETTS-----------
TH_0390|M.thermoresistible__bu GWTPAYLSVVALGVLTIALTLALVQNTPDGRAAPATMGT-----------
Mflv_2530|M.gilvum_PYR-GCK GWSVAYASAAAGGVLLIVVVLLLVRDTPQGSAASPETMS-----------
Mvan_4127|M.vanbaalenii_PYR-1 GWSVAYASAAALGVLSIVLTLAIVRNTPDGSAATSETMS-----------
MAB_3302|M.abscessus_ATCC_1997 GVATALLFPAIVCAVSSAVCLVGIIDPPRPPRS-----------------
MAV_3846|M.avium_104 GPQAGLRFTALACVFGAVASVIGIVDPPRKPRA-----------------
MMAR_5094|M.marinum_M SVGSIFWVNVPIAVVAIVSVNIFVPTSRNPDRPPLDLPGLLVSTVGVTVL
MUL_4170|M.ulcerans_Agy99 SVGSVFWVNVPIAVVAIVSVNMFVPTSRNPDRPPLDLPGLLVSTVGVTVL
. . : .
Mb1766c|M.bovis_AF2122/97 ----RLKAAARLPVTWEMS-------FLYAIVFGGFVAFSNYLPTYITTI
Rv1737c|M.tuberculosis_H37Rv ----RLKAAARLPVTWEMS-------FLYAIVFGGFVAFSNYLPTYITTI
MSMEG_4767|M.smegmatis_MC2_155 ----VRDIPGSVKTVWLRPGNRLGFFTHMGTQFSVTVFALMWGVPYLTVA
TH_0390|M.thermoresistible__bu ----VREIAASLKTVWLRAGTRLGFFTHMGTQFSVTVFALMWGVPYLTVG
Mflv_2530|M.gilvum_PYR-GCK ----VRQTLASVKTVWLRPGTRLGFFTHMGTQFSITVFALMWGLPYLTVA
Mvan_4127|M.vanbaalenii_PYR-1 ----VRETLTSVKTVWLRPGTRLGFFTHMGTQFSITVFALMWGLPYLTEA
MAB_3302|M.abscessus_ATCC_1997 -----EAPEEHLANPYRGSRVLWLIHGVSVLLVVPQVVVWTFTLVWLVTD
MAV_3846|M.avium_104 -----SASDQELASPYRGSLTLWRIHAVAGLMMMPQTVTVTFMLVWLIRN
MMAR_5094|M.marinum_M TYTLIEAPNIGWASARTAAGFALAVVLLAVFLWLERRTWHPILDLSIFAN
MUL_4170|M.ulcerans_Agy99 TYTLIETPNIGWASARTAAGFALAVVLLAVFLWLERRTWHPILDLSIFAN
. :
Mb1766c|M.bovis_AF2122/97 YGFSTVDAGARTAGFALAA---------------------------VLAR
Rv1737c|M.tuberculosis_H37Rv YGFSTVDAGARTAGFALAA---------------------------VLAR
MSMEG_4767|M.smegmatis_MC2_155 QGLSTAAAGALLTVSVVTA---------------------------ISAG
TH_0390|M.thermoresistible__bu QGLSTQMAGAMLTLSVAVA---------------------------IVAG
Mflv_2530|M.gilvum_PYR-GCK QGLSPGVAGALLSLSVVTG---------------------------IGSG
Mvan_4127|M.vanbaalenii_PYR-1 QGLSAGVAGALLSLSVVSA---------------------------IGCG
MAB_3302|M.abscessus_ATCC_1997 RGWSIGAASVMVTVAQLVG---------------------------ALGR
MAV_3846|M.avium_104 LHWSVAAAGALVTLSQLLG---------------------------ALGR
MMAR_5094|M.marinum_M RRFSGGTAAVTTAYLVMCGFIFVATQYLQFVAAYRAFDTGVRLVPLAFSY
MUL_4170|M.ulcerans_Agy99 RRFSGGTAAVTTAYLVMCGFIFVATQYLQFVAAYRAFDTGVRLVPLAFSY
* *.. : .
Mb1766c|M.bovis_AF2122/97 PVGGWLSDRIAPR----HVVLASLAG-TALLAFAAALQPPPEVWSAATFI
Rv1737c|M.tuberculosis_H37Rv PVGGWLSDRIAPR----HVVLASLAG-TALLAFAAALQPPPEVWSAATFI
MSMEG_4767|M.smegmatis_MC2_155 VAIGIFTGRHPHRR--SRLVLWIIASNASIWTIVLALPGPAPTWLLVVLI
TH_0390|M.thermoresistible__bu VLIGIFTGRHPHRR--SRLVLAIIASNAAAWTAVLALPDRAPLWLLITLI
Mflv_2530|M.gilvum_PYR-GCK VLIGVVTGRYPHRR--SWIVLGIIASNALMWTIVLALSGPAPLWVLVVLV
Mvan_4127|M.vanbaalenii_PYR-1 VLIGILTGRYPHRR--SRMVLAIITSNAVVWTVVLALPGPAPLWLLIVLI
MAB_3302|M.abscessus_ATCC_1997 VAAGMWSDRWGSRMRPIRAIAAAASATMALLAVTNQLDWSVSVVVMLVAS
MAV_3846|M.avium_104 VAVGRWSDRLGSRMRPVRYIAAAAVLVLLLLAWADYLNSRWQAGLMVAIS
MMAR_5094|M.marinum_M AGLSVIAPRIVERVGTTAVVTSGLVMVAVSVACAGGFDAGTPYWLIAAVM
MUL_4170|M.ulcerans_Agy99 AGLSVIAPRIVERVGTTAVVTSGLVMVAVSVACAGGFDAGTPYWLIAAVM
. : * * : : . : .
Mb1766c|M.bovis_AF2122/97 TLAVCL-GVGTGGVFAWVARRAPAASVGSVTGIVAAAGGLGGYFPPLVMG
Rv1737c|M.tuberculosis_H37Rv TLAVCL-GVGTGGVFAWVARRAPAASVGSVTGIVAAAGGLGGYFPPLVMG
MSMEG_4767|M.smegmatis_MC2_155 VIISVG-GPGSMVGFDFARTFNPSATLGTAQGMVNMGGFLASLIVMQAMG
TH_0390|M.thermoresistible__bu VVISVG-GPGSMVGFDFARTFNPSATLGTAQGMVNMGGFLASLLVMQAMG
Mflv_2530|M.gilvum_PYR-GCK AVISVG-GPGSMVGFDFARTFNTGATLGTAQGMVNMGGFLASLLLMQAMG
Mvan_4127|M.vanbaalenii_PYR-1 VVISVG-GPGSMVGFDFARTFNPRATLGTAQGMVNMGGFIASLLLMQAMG
MAB_3302|M.abscessus_ATCC_1997 VITVSDNGLAYTSIAEIAG----PFWSGRALGAQNTGQLLAAAVAPPIFG
MAV_3846|M.avium_104 VIAVLDNGLEATAITEFAG----PYWSGRALGIQNTTQRMMAAAGPPLFG
MMAR_5094|M.marinum_M AALGSGLGLTMAPASEAIMGSLSPTAAGVGSAVTGVARQLGACLGVAIVG
MUL_4170|M.ulcerans_Agy99 AALGSGLGLTMAPASEAIMGSLSPTAAGVGSAVTGVARQLGACLGVAIVG
. * * . : . .*
Mb1766c|M.bovis_AF2122/97 ATYDPVD----NDYTVGLLLLVATALVACT---YTALHAREPVSEEASR-
Rv1737c|M.tuberculosis_H37Rv ATYDPVD----NDYTVGLLLLVATALVACT---YTALHAREPVSEEASR-
MSMEG_4767|M.smegmatis_MC2_155 VVLSHAGSYSFESFRLAWTVQYAIWILATIGILITRHKTRRLMAAEQERM
TH_0390|M.thermoresistible__bu QILDAAGGYSFDSFRLAWTVQYVVWVVAAVGILITRKKARRQMALEQERM
Mflv_2530|M.gilvum_PYR-GCK MVMDASGGLTFESFRTAWTLQYAVWTLAVLGVLITRRKARRQLAE-DDRF
Mvan_4127|M.vanbaalenii_PYR-1 MVMQAMGGISFESFRSAWMVQYVVWALAVVGILITRRKARRLLRDGNDRI
MAB_3302|M.abscessus_ATCC_1997 AIAAAAGFSAAFAVCALFPLAAVGLVPVKLERPAP---------------
MAV_3846|M.avium_104 ALISAAKYPPAWLLCALFPLAAMPLVPTRLLPPGLETRARRQSVRRLRWW
MMAR_5094|M.marinum_M SVFASVYLRSMSSNAALHGLDPAARAAMRQSMAAAKQVLDQLPVGEAPAI
MUL_4170|M.ulcerans_Agy99 SVFASVYLRSMSSNAALHGLDPAARAAMRQSMAAAKQVLDQLPVGEAPAI
:
Mb1766c|M.bovis_AF2122/97 --------------------------------------------------
Rv1737c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_4767|M.smegmatis_MC2_155 LLEGFEAHPPR---------------------------------------
TH_0390|M.thermoresistible__bu LLESFEPGPRRHTGPDRTNRPHG---------------------------
Mflv_2530|M.gilvum_PYR-GCK LLEDIQT-------------------------------------------
Mvan_4127|M.vanbaalenii_PYR-1 LLEGVNP-------------------------------------------
MAB_3302|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3846|M.avium_104 RAVRSHALPDIVRRPGQPG-------------------------------
MMAR_5094|M.marinum_M RHAVESAFLESFGVGCLACAVFAAVGAVVVAFLLPARGEVRDDVAVSVAA
MUL_4170|M.ulcerans_Agy99 RHAVESAFLESFGVGCLACAVFAAVGAVVVAFLLPARGEVRDDVAVSVAA
Mb1766c|M.bovis_AF2122/97 ----------
Rv1737c|M.tuberculosis_H37Rv ----------
MSMEG_4767|M.smegmatis_MC2_155 ----------
TH_0390|M.thermoresistible__bu ----------
Mflv_2530|M.gilvum_PYR-GCK ----------
Mvan_4127|M.vanbaalenii_PYR-1 ----------
MAB_3302|M.abscessus_ATCC_1997 ----------
MAV_3846|M.avium_104 ----------
MMAR_5094|M.marinum_M SAIGPAEGGK
MUL_4170|M.ulcerans_Agy99 SAIGPAEGGK