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FTRSLKWITRGGWIADMPSRFPPAPHKDRIEAILAANHEQLGPQALAPEYDMPEAKFTPRDVSSPPFQGD LYAWLVMQRKPQTVVEFGSGFGVSGMYFGAGIESNGTGHLYSFEINDSWAAVAERSIAQLTQRFTLTRGA FEEHVTEVPGPIDIAFVDGIHTYDFVMQQWEILKPLMSPGGLVLFDDITYGQGMHEAWLEIGRSDDVVGA VEFRRNNRLGLAECR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4739 | - | - | 100% (226) | hypothetical protein MSMEG_4739 |
| M. smegmatis MC2 155 | MSMEG_5003 | - | 3e-13 | 32.12% (137) | O-methyltransferase, family protein 3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2983c | - | 2e-05 | 26.76% (142) | methyltransferase (methylase) |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2959c | - | 2e-05 | 26.76% (142) | methyltransferase (methylase) |
| M. leprae Br4923 | MLBr_00127 | - | 1e-05 | 26.43% (140) | hypothetical protein MLBr_00127 |
| M. abscessus ATCC 19977 | MAB_3463 | - | 1e-11 | 28.35% (127) | O-methyltransferase family protein |
| M. marinum M | MMAR_0313 | - | 1e-13 | 33.87% (124) | O-methyltransferase |
| M. avium 104 | MAV_3257 | - | 2e-61 | 55.25% (219) | hypothetical protein MAV_3257 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4809 | - | 4e-14 | 33.87% (124) | O-methyltransferase |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4739|M.smegmatis_MC2_155 MFTRSLKWITRGGWIADMPSRFPPAPHKDRIEAILAANHEQLGPQALAPE
MAV_3257|M.avium_104 ---MELKWVKRGGRIAGLPRRLPPAARKSGIESS-ARGTDKLGALPLAEA
MMAR_0313|M.marinum_M -----MGTTLQDAKVAAALDRMYAAAAN---EMTALRERRAEIERLWSGD
MUL_4809|M.ulcerans_Agy99 -----MGTTLQDAKVAAALDRMYAAAAN---EMTALRERRAEIERLWSGD
MAB_3463|M.abscessus_ATCC_1997 -----MTATLHEPKFAAIIDRLFRNAAN---DPIPT-DR----DTFHKKS
Mb2983c|M.bovis_AF2122/97 MGLVWRSRTSLVGQLIGLVRLVASFAAQ--LFYRPSDAVAEEYHKWYYGN
Rv2959c|M.tuberculosis_H37Rv MGLVWRSRTSLVGQLIGLVRLVASFAAQ--LFYRPSDAVAEEYHKWYYGN
MLBr_00127|M.leprae_Br4923 ---------------MERVRQMFSCVSG--MIYRPTDSIAEEYHKWYYGN
.
MSMEG_4739|M.smegmatis_MC2_155 YDMPEAKFTPRDVSSPPFQGDLYAWLVMQRKPQTVVEFGSGFGVSGMYFG
MAV_3257|M.avium_104 YGQPGAARKPKQVRAASWQGDLYAYLVRWRDPGIVVEFGSAFGVSGMYLS
MMAR_0313|M.marinum_M AQQRADAMSEFYIPVTPEAGRLMYALVRAIRPTTVVEFGMSFGISTIHLA
MUL_4809|M.ulcerans_Agy99 AQQRADAMSEFYIPVTPEAGRLMYALVRAIRPTTVVEFGMSFGISTIHLA
MAB_3463|M.abscessus_ATCC_1997 VEERIELFENIYVPVAPDAGRLLYSLVRAIKPRTIVEYGLSYGISTLHSA
Mb2983c|M.bovis_AF2122/97 LVWTKTTYMGINCWKSVSDMWNYQEILSELQPSLVIEFGTRYGGSAVYFA
Rv2959c|M.tuberculosis_H37Rv LVWTKTTYMGINCWKSVSDMWNYQEILSELQPSLVIEFGTRYGGSAVYFA
MLBr_00127|M.leprae_Br4923 FVWNTTTWMGIKCLKSVSDMWNYQEILIELEPSLVIEFGSRFGGSALFFA
. :: * ::*:* :* * :. .
MSMEG_4739|M.smegmatis_MC2_155 AGIESNGTGHLYSFEINDSWAAVAERSIAQ--LTQRFTLTRGAFEEHVTE
MAV_3257|M.avium_104 SELRR---GWLYSFEINPSWADIAERNIKS--VTDRCTLTRGAFEDHVDD
MMAR_0313|M.marinum_M AAVRDNGSGRVVTTELNASKIAAAKQTFADTGLADVITVAEGDALATLTT
MUL_4809|M.ulcerans_Agy99 AAVRDNGSGRVVTTELNASKIAAAKQTFADTELADVITVAEGDALATLTT
MAB_3463|M.abscessus_ATCC_1997 AAVRDNGFGRIITTEMNTAKIAASRATFAEAGVSDLITILEGDARETLKT
Mb2983c|M.bovis_AF2122/97 NIMRQIGQPFKVLTVDNSHKALDPRARREPDVLFVESSSTDPAIAEQIQR
Rv2959c|M.tuberculosis_H37Rv NIMRQIGQPFKVLTVDNSHKALDPRARREPDVLFVESSSTDPAIAEQIQR
MLBr_00127|M.leprae_Br4923 NVMMHIGQPFKVLSVDISHKDLDPAAR-QPDILFIESPSTAPAIAEQIRR
: . : . :
MSMEG_4739|M.smegmatis_MC2_155 VPGPID---IAFVDGIHTYDFVMQQWEILKPLMSPGGLVLFDDITYGQG-
MAV_3257|M.avium_104 IPAPID---MALVDGIHSYDFVARQWQLLKPRMAPGGWVLFDDIDFNPG-
MMAR_0313|M.marinum_M VPGPVQ---FVLLDGWK--DLYLPVVRLLEPVLPAGALILADNTESAG--
MUL_4809|M.ulcerans_Agy99 VPGPVQ---FVLLDGWK--DLYLPVVRLLEPVLPAGALILADNTESAG--
MAB_3463|M.abscessus_ATCC_1997 IDSPID---FLLLDGWP--DLDLTILNIVEDKLAPGALVIADNVGFES--
Mb2983c|M.bovis_AF2122/97 LKNEYPGKIFAILDSDHSMNHVLAEMKLLRPLLSAGDYLVVEDSNINGHP
Rv2959c|M.tuberculosis_H37Rv LKNEYPGKIFAILDSDHSMNHVLAEMKLLRPLLSAGDYLVVEDSNINGHP
MLBr_00127|M.leprae_Br4923 LKNEYPGKIFAILDSDHSMKQVLAEMKLLQPLLTAGDYLVVEDSNLNGHP
: : ::*. . .::. :..* :: ::
MSMEG_4739|M.smegmatis_MC2_155 -----MHEAWLEIGRSDD---VVGAVEFRRNNRLGLAECR-------
MAV_3257|M.avium_104 -----MGKAWQDICAEPH---VVGAVEVSK--RLGLIELAP------
MMAR_0313|M.marinum_M ------SRPYLDYIRDPANGYVSFNFPARSSDSMEISCRTAD-----
MUL_4809|M.ulcerans_Agy99 ------SRPYLDYIRDPANGYVSFNFPARSSDSMEISCRTAD-----
MAB_3463|M.abscessus_ATCC_1997 ------SKPYLEYVRNPENGYVSVASPIGECMELSTSCKK-------
Mb2983c|M.bovis_AF2122/97 VLPGFGPGPYEAIEAYEDEFPNDYKHDAERENKFGWTSAPNGFLIRN
Rv2959c|M.tuberculosis_H37Rv VLPGFGPGPYEAIEAYEDEFPNDYKHDAERENKFGWTSAPNGFLIRN
MLBr_00127|M.leprae_Br4923 VLPRFGAGPYEAIEAYEREFPGDYEHDVAREKKFGFTFATNGFLIRK
.: :