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MTATLHEPKFAAIIDRLFRNAANDPIPTDRDTFHKKSVEERIELFENIYVPVAPDAGRLLYSLVRAIKPR TIVEYGLSYGISTLHSAAAVRDNGFGRIITTEMNTAKIAASRATFAEAGVSDLITILEGDARETLKTIDS PIDFLLLDGWPDLDLTILNIVEDKLAPGALVIADNVGFESSKPYLEYVRNPENGYVSVASPIGECMELST SCKK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3463 | - | - | 100% (214) | O-methyltransferase family protein |
| M. abscessus ATCC 19977 | MAB_4548 | - | 2e-12 | 30.71% (127) | O-methyltransferase |
| M. abscessus ATCC 19977 | MAB_1318c | - | 3e-12 | 30.38% (158) | catechol-o-methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1729c | - | 7e-10 | 27.22% (158) | catechol-o-methyltransferase |
| M. gilvum PYR-GCK | Mflv_3499 | - | 1e-10 | 29.56% (159) | catechol O-methyltransferase |
| M. tuberculosis H37Rv | Rv1703c | - | 7e-10 | 27.22% (158) | catechol-o-methyltransferase |
| M. leprae Br4923 | MLBr_02669 | - | 1e-06 | 30.53% (95) | hypothetical protein MLBr_02669 |
| M. marinum M | MMAR_0313 | - | 3e-57 | 46.79% (218) | O-methyltransferase |
| M. avium 104 | MAV_5200 | - | 4e-58 | 48.61% (216) | O-methyltransferase, family protein 3 |
| M. smegmatis MC2 155 | MSMEG_5003 | - | 5e-36 | 42.62% (183) | O-methyltransferase, family protein 3 |
| M. thermoresistible (build 8) | TH_1541 | - | 9e-10 | 29.56% (159) | Probable catechol-o-methyltransferase |
| M. ulcerans Agy99 | MUL_4809 | - | 2e-56 | 46.33% (218) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_3280 | - | 1e-09 | 27.74% (155) | catechol O-methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0313|M.marinum_M ---------MGTTLQDAKVAAALDRMYAAAANEMTALRERRAEIER---L
MUL_4809|M.ulcerans_Agy99 ---------MGTTLQDAKVAAALDRMYAAAANEMTALRERRAEIER---L
MAV_5200|M.avium_104 ---------MTTTLQDPRVASALDRMYSESKNQMSLLRQRRGTFDQ---P
MAB_3463|M.abscessus_ATCC_1997 ---------MTATLHEPKFAAIIDRLFRNAAN--DPIPTDRDTFHK---K
MLBr_02669|M.leprae_Br4923 ---------MTSYIIHTSIPHPEAGLLLTYWYG-----------------
MSMEG_5003|M.smegmatis_MC2_155 ---------MTTTLTSDPVSTVLHGLLRAEQDGDAAAFAEVGEFPLDAA-
Mb1729c|M.bovis_AF2122/97 --------------------------------------------------
Rv1703c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3499|M.gilvum_PYR-GCK MNALRRWARLALGMRSFVRTGQMGDGRESACADHVETHAAPGDIDA----
Mvan_3280|M.vanbaalenii_PYR-1 MNAIRRWARLALGMPSFVRTGQIGDGREAACAAYVEANAPRGDIDA----
TH_1541|M.thermoresistible__bu ---------MTMTQHRLTTTGQIGDGREAAAADYVERHARPGDIDD----
MMAR_0313|M.marinum_M WSGDAQQRADAMSEFYIPVTPEAGRLMYALVRAIRPTTVVEFGMSFGIST
MUL_4809|M.ulcerans_Agy99 WSGDAQQRADAMSEFYIPVTPEAGRLMYALVRAIRPTTVVEFGMSFGIST
MAV_5200|M.avium_104 MT--AQQRADAMIEFYIPVTPEAGRLLYSLVRATRPATVVEFGMSFGISA
MAB_3463|M.abscessus_ATCC_1997 SV---EERIELFENIYVPVAPDAGRLLYSLVRAIKPRTIVEYGLSYGIST
MLBr_02669|M.leprae_Br4923 -----------------------------LIRTN---TVVEFGTSFSSHA
MSMEG_5003|M.smegmatis_MC2_155 ----PAERAEVLKNVYMSVSQTGGELLYLLARATGARTVVEYGTSFGVST
Mb1729c|M.bovis_AF2122/97 -MLATIDKFAYEKSMLINVGDEKGTLLDAAVRRADPALALELGTYLGYGA
Rv1703c|M.tuberculosis_H37Rv -MLATIDKFAYEKSMLINVGDEKGTLLDAAVRRADPALALELGTYLGYGA
Mflv_3499|M.gilvum_PYR-GCK -ALSAIDGFAVREAVLVNVGVEKGALLDAAVRRADPALALELGTYCGYSA
Mvan_3280|M.vanbaalenii_PYR-1 -ALSAIDTFAYRKAMLVNIGDEKGALLDAAVRRADPALVLELGTYCGYSA
TH_1541|M.thermoresistible__bu -VLDIIDEYAYRKSFLVNIGDEKGLLLDAAVRRADPELALELGTYCGYGA
* :* * . :
MMAR_0313|M.marinum_M IHLAAAVR--DNGSGRVVTTELNASKIAAAKQTFADTGLADVITVAEG--
MUL_4809|M.ulcerans_Agy99 IHLAAAVR--DNGSGRVVTTELNASKIAAAKQTFADTELADVITVAEG--
MAV_5200|M.avium_104 VHLAAAVR--DNGSGRVVTTELSDTKIAAAKKTFAETGLDDVITILHG--
MAB_3463|M.abscessus_ATCC_1997 LHSAAAVR--DNGFGRIITTEMNTAKIAASRATFAEAGVSDLITILEG--
MLBr_02669|M.leprae_Br4923 IHLAAVIRPHNDSGDWSVPAELSATKSAGAKQMFNTNGLNYLITVLKE--
MSMEG_5003|M.smegmatis_MC2_155 IYLASAVR--DNGGGTVITTELQPGKAAAAQRSFDTAGLGDLIDLRIG--
Mb1729c|M.bovis_AF2122/97 LRIARAAP-----EARVYSVELAEANASNARRIWAHAGVDDRVVCVVGTI
Rv1703c|M.tuberculosis_H37Rv LRIARAAP-----EARVYSVELAEANASNARRIWAHAGVDDRVVCVVGTI
Mflv_3499|M.gilvum_PYR-GCK LRIARAAP-----SARVLSVEFSAANAEVARRIWTHAGVADRVTCVVGTL
Mvan_3280|M.vanbaalenii_PYR-1 LRIARAAP-----SARVLSVEFSAANADVARRIWAHAGVGDRVTCVVGTL
TH_1541|M.thermoresistible__bu LRIARAAP-----AARVISVELAEANAQVARRIWAHAGVSDRISCVVGTI
: * . ..*: : :: : : :
MMAR_0313|M.marinum_M -DALATLTTVP-------GPVQFVLLDGWKDLYLPVVRLLEP--VLPAGA
MUL_4809|M.ulcerans_Agy99 -DALATLTTVP-------GPVQFVLLDGWKDLYLPVVRLLEP--VLPAGA
MAV_5200|M.avium_104 -DALTTLADLP-------GPVDFVLLDGWKDLYLPVLELLEP--RLSPGV
MAB_3463|M.abscessus_ATCC_1997 -DARETLKTID-------SPIDFLLLDGWPDLDLTILNIVED--KLAPGA
MLBr_02669|M.leprae_Br4923 -RYASNLVKIH-------RSVEFV--------------------------
MSMEG_5003|M.smegmatis_MC2_155 -DARDTLVHVP-------RPVDLVLLDGWPDLALPVLKVLEP--HLRAGT
Mb1729c|M.bovis_AF2122/97 GDGGRTLDALT-EHGFATGTLDFVFLDHDKKAYLPDLQSILDRGWLHPGS
Rv1703c|M.tuberculosis_H37Rv GDGGRTLDALT-EHGFATGTLDFVFLDHDKKAYLPDLQSILDRGWLHPGS
Mflv_3499|M.gilvum_PYR-GCK GDGGRTLDSLAGEHGVGPGSVDLLFIDHDNSAYLSDLLSIEQRGWLHRGS
Mvan_3280|M.vanbaalenii_PYR-1 GDGGRTLDTLAREHGVTTGSVDLLFIDHDKKAYLSDLRSVEQRGWLHRGS
TH_1541|M.thermoresistible__bu DDGGRTLEALNREHKVSAAALGLVFLDHNKERYLPDLRTIMDQGWLRPGA
.* : .: ::
MMAR_0313|M.marinum_M LILADNTESAGSRPYLDYIRDPANG----YVSFNFPARSSDSMEISCRTA
MUL_4809|M.ulcerans_Agy99 LILADNTESAGSRPYLDYIRDPANG----YVSFNFPARSSDSMEISCRTA
MAV_5200|M.avium_104 LVVADNTSAADTQPYLDRVRNPDNG----YVSFNFQVRDSDSMEISCRTS
MAB_3463|M.abscessus_ATCC_1997 LVIADNVGFESSKPYLEYVRNPENG----YVSVASPIGECMELSTSCKK-
MLBr_02669|M.leprae_Br4923 --------------------------------------------------
MSMEG_5003|M.smegmatis_MC2_155 LILVDDVNLDFGGRDLHGALLDHLATCGHYRTLTLPIGDGIEACVRLSDG
Mb1729c|M.bovis_AF2122/97 IVVADNVRVPGAPKYRAYMRRQQGMSWNTIEHKTHLEYQTLVPDLVLESE
Rv1703c|M.tuberculosis_H37Rv IVVADNVRVPGAPKYRAYMRRQQGMSWNTIEHKTHLEYQTLVPDLVLESE
Mflv_3499|M.gilvum_PYR-GCK LVVADNVRIPGAPEYRRYMREHEGTRWHTVEHKTHVEYQSLLPDLVLESE
Mvan_3280|M.vanbaalenii_PYR-1 IVVADNVRVPGAPDYRRHMREQQGTRWNTVEHKTHVEYQSLLPDLVLESE
TH_1541|M.thermoresistible__bu VVVADNVRLPGSPRYRAYMREQQGITWRTTEHKTHGEYGIELPDLVLESV
MMAR_0313|M.marinum_M D----
MUL_4809|M.ulcerans_Agy99 D----
MAV_5200|M.avium_104 G----
MAB_3463|M.abscessus_ATCC_1997 -----
MLBr_02669|M.leprae_Br4923 -----
MSMEG_5003|M.smegmatis_MC2_155 AKG--
Mb1729c|M.bovis_AF2122/97 YLG--
Rv1703c|M.tuberculosis_H37Rv YLG--
Mflv_3499|M.gilvum_PYR-GCK YLVGS
Mvan_3280|M.vanbaalenii_PYR-1 YLGS-
TH_1541|M.thermoresistible__bu YLGG-