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M. tuberculosis H37Rv Rv2959c (-)

annotation: POSSIBLE METHYLTRANSFERASE (METHYLASE)
coordinates: 3312101 - 3312838
length: 245

GLVWRSRTSLVGQLIGLVRLVASFAAQLFYRPSDAVAEEYHKWYYGNLVWTKTTYMGINCWKSVSDMWNY
QEILSELQPSLVIEFGTRYGGSAVYFANIMRQIGQPFKVLTVDNSHKALDPRARREPDVLFVESSSTDPA
IAEQIQRLKNEYPGKIFAILDSDHSMNHVLAEMKLLRPLLSAGDYLVVEDSNINGHPVLPGFGPGPYEAI
EAYEDEFPNDYKHDAERENKFGWTSAPNGFLIRN*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2959c--100% (245)POSSIBLE METHYLTRANSFERASE (METHYLASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2983c-1e-145100.00% (245) methyltransferase (methylase)
M. gilvum PYR-GCK-----
M. leprae Br4923MLBr_00127-1e-10076.11% (226) hypothetical protein MLBr_00127
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_4739-3e-0526.76% (142) hypothetical protein MSMEG_4739
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv2959c|M.tuberculosis_H37Rv        MGLVWRSRTSLVGQLIGLVRLVASFAAQLFYRPSDAVAEEYHKWY-----
Mb2983c|M.bovis_AF2122/97           MGLVWRSRTSLVGQLIGLVRLVASFAAQLFYRPSDAVAEEYHKWY-----
MLBr_00127|M.leprae_Br4923          ---------------MERVRQMFSCVSGMIYRPTDSIAEEYHKWY-----
MSMEG_4739|M.smegmatis_MC2_155      ---MFTRSLKWITRGGWIADMPSRFPPAPHKDRIEAILAANHEQLGPQAL
                                                      .       .       :::    *:       

Rv2959c|M.tuberculosis_H37Rv        YGNLVWTKTTYMGINCWKSVSDMWNYQEILSELQPSLVIEFGTRYGGSAV
Mb2983c|M.bovis_AF2122/97           YGNLVWTKTTYMGINCWKSVSDMWNYQEILSELQPSLVIEFGTRYGGSAV
MLBr_00127|M.leprae_Br4923          YGNFVWNTTTWMGIKCLKSVSDMWNYQEILIELEPSLVIEFGSRFGGSAL
MSMEG_4739|M.smegmatis_MC2_155      APEYDMPEAKFTPRDVSSPPFQGDLYAWLVMQRKPQTVVEFGSGFGVSGM
                                      :     :.:   .  ..  :   *  :: : :*. *:***: :* *.:

Rv2959c|M.tuberculosis_H37Rv        YFANIMRQIG-QPFKVLTVDNSHKALDPRARREPDVLFVESSSTDPAIAE
Mb2983c|M.bovis_AF2122/97           YFANIMRQIG-QPFKVLTVDNSHKALDPRARREPDVLFVESSSTDPAIAE
MLBr_00127|M.leprae_Br4923          FFANVMMHIG-QPFKVLSVDISHKDLDPAAR-QPDILFIESPSTAPAIAE
MSMEG_4739|M.smegmatis_MC2_155      YFGAGIESNGTGHLYSFEINDSWAAVAERSIAQLTQRFTLTRG---AFEE
                                    :*.  :   *   :  : :: *   :   :  :    *  : .   *: *

Rv2959c|M.tuberculosis_H37Rv        QIQRLKNEYPGKIFAILDSDHSMNHVLAEMKLLRPLLSAGDYLVVEDSNI
Mb2983c|M.bovis_AF2122/97           QIQRLKNEYPGKIFAILDSDHSMNHVLAEMKLLRPLLSAGDYLVVEDSNI
MLBr_00127|M.leprae_Br4923          QIRRLKNEYPGKIFAILDSDHSMKQVLAEMKLLQPLLTAGDYLVVEDSNL
MSMEG_4739|M.smegmatis_MC2_155      HVTEVPGPID---IAFVDGIHTYDFVMQQWEILKPLMSPGGLVLFDD---
                                    :: .: .      :*::*. *: . *: : ::*:**::.*. ::.:*   

Rv2959c|M.tuberculosis_H37Rv        NGHPVLPGFGPGPYEAIEAYEDEFPNDYKHDAERENKFGWTSAPNGFLIR
Mb2983c|M.bovis_AF2122/97           NGHPVLPGFGPGPYEAIEAYEDEFPNDYKHDAERENKFGWTSAPNGFLIR
MLBr_00127|M.leprae_Br4923          NGHPVLPRFGAGPYEAIEAYEREFPGDYEHDVAREKKFGFTFATNGFLIR
MSMEG_4739|M.smegmatis_MC2_155      ------ITYGQGMHEAWLEIGRSDDVVGAVEFRRNNRLGLAECR------
                                            :* * :**      .       :  *::::* : .       

Rv2959c|M.tuberculosis_H37Rv        N
Mb2983c|M.bovis_AF2122/97           N
MLBr_00127|M.leprae_Br4923          K
MSMEG_4739|M.smegmatis_MC2_155      -