For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTTLGVIGLGRIGAFHVDTLSSLDGVDGLVVADERPDAVAAVAAKHGAKPADSVEELLDSGVDGVVVAAA TPAHAELTLAAVHRGLPTFCEKPIAATAAESARVAEAIARSGVPVQVGYQRRFDAAFAAAKREVDSGSLG ALHTVRSTTMDPAPPSMDYIKGSGGIFRDCAVHDFDALRWITGQNAVEVYATGTVQGDPRFTEYGDVDTA AVVVRFDGGALGIVSAARYNARGYDCRLEVHGFDNSIVAGWDQGTPLQNMDPRNDFPTGPYHHFFMDRFT EAFRSELAGFVEVVKGNPIPGATVADAVEVAWMAEAATESLRRGAPVRIEEVRNR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4650 | - | - | 100% (335) | oxidoreductase YisS |
| M. smegmatis MC2 155 | MSMEG_6717 | - | 3e-25 | 28.61% (360) | oxidoreductase, Gfo/Idh/MocA family protein |
| M. smegmatis MC2 155 | MSMEG_4666 | - | 2e-21 | 28.57% (343) | myo-inositol 2-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2613 | - | 1e-158 | 80.48% (333) | inositol 2-dehydrogenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2612 | - | 2e-14 | 22.66% (353) | putative oxidoreductase |
| M. marinum M | MMAR_2628 | - | 6e-11 | 26.32% (323) | hypothetical protein MMAR_2628 |
| M. avium 104 | MAV_1941 | - | 5e-18 | 27.17% (265) | oxidoreductase family protein, NAD-binding Rossmann fold |
| M. thermoresistible (build 8) | TH_3104 | - | 1e-08 | 34.09% (88) | PUTATIVE oxidoreductase domain protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3968 | - | 1e-158 | 80.42% (337) | inositol 2-dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2613|M.gilvum_PYR-GCK ------MTSLGLIGLGRIG-AFHTETLINLPEVSRLVITDERPGVVGEVA
Mvan_3968|M.vanbaalenii_PYR-1 ------MTTLGLIGLGRIG-AFHAETLTNLPEVSGLVVTDERPEVVSQLA
MSMEG_4650|M.smegmatis_MC2_155 ------MTTLGVIGLGRIG-AFHVDTLSSLDGVDGLVVADERPDAVAAVA
MAV_1941|M.avium_104 -----MTLRVGIIGVGWGA-HVQVPGFRAAKGYEPVALCARTPERLERVA
TH_3104|M.thermoresistible__bu -------MRVLVIGTGFGR-QAMAPVYRGLG-FDVEVVSPRDESALHRAL
MAB_2612|M.abscessus_ATCC_1997 ------MLKVGIIGAGGVA-RAHARALNTLKSAELVGVLDIDARAAESFT
MMAR_2628|M.marinum_M MTGHGSPLRIGILGAARIAPQALVKPAQGNVEAVVAAVAARDGARAQAFA
: ::* . . :
Mflv_2613|M.gilvum_PYR-GCK AKYGATPVESVEKLLSS--GIDGVVVAAATPAHAELTLAAVERGLPTFCE
Mvan_3968|M.vanbaalenii_PYR-1 TKYGATPANSVQELLAS--GVDGVIVAAATPAHAELTLAAVERGLPTFCE
MSMEG_4650|M.smegmatis_MC2_155 AKHGAKPADSVEELLDS--GVDGVVVAAATPAHAELTLAAVHRGLPTFCE
MAV_1941|M.avium_104 DKLGIEETSTDWESFVTRDDLDVISVATPTVLHRDMTLAALAAGKPVLCE
TH_3104|M.thermoresistible__bu NAG-----------------VDLVSVHSPPFLHRQHVTAAVDRGYPVLCD
MAB_2612|M.abscessus_ATCC_1997 DAYGGTPVTDVDALLEL---ADAVVVASPNFTHRDHSLSALRAGRSVLCE
MMAR_2628|M.marinum_M AKHGISRVHSSYEALIADPTLDAVYIPLPNGLHGRWTQAALTAGKHVLCE
* : : . * :*: * .:*:
Mflv_2613|M.gilvum_PYR-GCK KPIASTAAESARVAEIIARSGVPVQVGYQRRFDTAFAAVKQAADSGSLGA
Mvan_3968|M.vanbaalenii_PYR-1 KPIAATAAESARVGEVITRSGVPVQVGYQRRFDAAFAAVKHAVDDGSLGA
MSMEG_4650|M.smegmatis_MC2_155 KPIAATAAESARVAEAIARSGVPVQVGYQRRFDAAFAAAKREVDSGSLGA
MAV_1941|M.avium_104 KPLAGDLDAARDMVRAAAEANVPTACCFENRWNPDWLAVADRVRSGFLGT
TH_3104|M.thermoresistible__bu KPFGRNADEARAMRDHAARRAVPTFLNFELRHQPARAEFKKLADSGVIGT
MAB_2612|M.abscessus_ATCC_1997 KPLALSRVEAKEMVAAAGEIASPALVGFNYRHLPVVTELRRRLQHGDFGT
MMAR_2628|M.marinum_M KPFTANAAEADEIAQLAATTDRVVMEAFHYRYHPLTLRIEQILASGELGT
**: : : . :. * . * :*:
Mflv_2613|M.gilvum_PYR-GCK LHTVRST-------TMDPAPPPMDYIRG-SGGIFRDCAVHDFDVIRWVTG
Mvan_3968|M.vanbaalenii_PYR-1 LHTVRST-------TMDPAPPPMDYIKG-SGGIFRDCAVHDFDVIRWVTG
MSMEG_4650|M.smegmatis_MC2_155 LHTVRST-------TMDPAPPSMDYIKG-SGGIFRDCAVHDFDALRWITG
MAV_1941|M.avium_104 QYLARVSRSASYWHPSHPLQAHWMYDREQGGGYLAGMLVHDLDFLCSLLG
TH_3104|M.thermoresistible__bu PRHLSWTFFG---AGLRGRPHGWINERDTGGGWIGANGAHLIDYTRYLFG
MAB_2612|M.abscessus_ATCC_1997 ICAVELGFRKDSAYRRKNHTWRDSGRSNGTSGALGDLGVHLLDLLTYISG
MMAR_2628|M.marinum_M LQRVETS-----MCFPLPKFSDIRYNYALAGGATMDAGCYAVHMARTFGG
.* : .. . *
Mflv_2613|M.gilvum_PYR-GCK QNVVEVYATGSVQGDPLFTEYG------DVDTAAIVVRFDGGALGVVSAA
Mvan_3968|M.vanbaalenii_PYR-1 QNVVDVYATGSVQGDPRFAEYG------DVDTAAVVVRFDGGALGVVSAA
MSMEG_4650|M.smegmatis_MC2_155 QNAVEVYATGTVQGDPRFTEYG------DVDTAAVVVRFDGGALGIVSAA
MAV_1941|M.avium_104 RPVSVCAEVRTSDPVRELPDGGTLH-VTADDTAAVLMRMESGVTAVLSVS
TH_3104|M.thermoresistible__bu SEITGCGGVARIEDPHRPDPQGRPRRATAEDAYSAWFVTENGCTATHDTA
MAB_2612|M.abscessus_ATCC_1997 GRILVDECQARITTHVTNKSDE---AVEVDDHAEIYGRLSTGSIFTLVAS
MMAR_2628|M.marinum_M GTPEVVSAQAKRRDSE------------VDRAMTAELRFPAGHSGRIQCS
* :
Mflv_2613|M.gilvum_PYR-GCK RYN-GRGYDCRLEVHGFDDTVVAGWDQG---APVRNADP-----ANDFPT
Mvan_3968|M.vanbaalenii_PYR-1 RYN-GRGYDCRLEVHGFDDTVVAGWDQG---APVRNADPDFSS-PGAFPA
MSMEG_4650|M.smegmatis_MC2_155 RYN-ARGYDCRLEVHGFDNSIVAGWDQG---TPLQNMDP-----RNDFPT
MAV_1941|M.avium_104 VMG-AHADHYRLELFGSDGTIIGDGDLR---SAAYSLGAATDDGLRSLAV
TH_3104|M.thermoresistible__bu FAA-AVALPPRMVLTGSAGALELIGDSR---LIVHRADADP--MTHEFPP
MAB_2612|M.abscessus_ATCC_1997 KAAPAADCGFSIRIVGTNAVFRYHTADPGRYLVSRGADTETVDLARTLLS
MMAR_2628|M.marinum_M MWS-SHLLNMSARVVGDRGELRVLNPVVP--QLFHRLTVQS-----AIGR
. : * . :
Mflv_2613|M.gilvum_PYR-GCK GQPH--HFFMDRFTEAFR--------TELSSFVDVVEGG-PNLGATVADA
Mvan_3968|M.vanbaalenii_PYR-1 GPPH--HFFMDRFTEAFR--------AELRAFVDVVEGG-PIRGATVADA
MSMEG_4650|M.smegmatis_MC2_155 GPYH--HFFMDRFTEAFR--------SELAGFVEVVKGN-PIPGATVADA
MAV_1941|M.avium_104 DERE--PAHPDRLPRGLAGHASRAMALMLQDWLPAFDGA-PSNVATFEDG
TH_3104|M.thermoresistible__bu APPR--SFYEPALTPWLE------------QVADALRTG-RPATPSFDDG
MAB_2612|M.abscessus_ATCC_1997 DPDNEVHGWSDSFRSEID---------HWSRLVAVGGGANRQALATFDDG
MMAR_2628|M.marinum_M RVER----FPRRASYAYQ----------LDAFTGAILRG-EAVKTTPQDA
. . .: *.
Mflv_2613|M.gilvum_PYR-GCK VEVAWIAEAATESLR-RGVPVTIDSVRKEAQQ-
Mvan_3968|M.vanbaalenii_PYR-1 VEVAWIAEAATESLR-RGVPVTIESVRKETQQ-
MSMEG_4650|M.smegmatis_MC2_155 VEVAWMAEAATESLR-RGAPVRIEEVRNR----
MAV_1941|M.avium_104 LLSLAIIDAARRSAE-GGGWEPVQA--------
TH_3104|M.thermoresistible__bu VAVAEVMDRLRANVI-EQVMQ------------
MAB_2612|M.abscessus_ATCC_1997 LAAQEVLESLLRGSKPQPERLPVEHTLPTPAEL
MMAR_2628|M.marinum_M VQNMTVIDAIYRAAG-LPLRNPS----------
: : :