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MTLRVGIIGVGWGAHVQVPGFRAAKGYEPVALCARTPERLERVADKLGIEETSTDWESFVTRDDLDVISV ATPTVLHRDMTLAALAAGKPVLCEKPLAGDLDAARDMVRAAAEANVPTACCFENRWNPDWLAVADRVRSG FLGTQYLARVSRSASYWHPSHPLQAHWMYDREQGGGYLAGMLVHDLDFLCSLLGRPVSVCAEVRTSDPVR ELPDGGTLHVTADDTAAVLMRMESGVTAVLSVSVMGAHADHYRLELFGSDGTIIGDGDLRSAAYSLGAAT DDGLRSLAVDEREPAHPDRLPRGLAGHASRAMALMLQDWLPAFDGAPSNVATFEDGLLSLAIIDAARRSA EGGGWEPVQA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1941 | - | - | 100% (360) | oxidoreductase family protein, NAD-binding Rossmann fold protein |
| M. avium 104 | MAV_2643 | - | 0.0 | 89.69% (359) | oxidoreductase family protein, NAD-binding Rossmann fold |
| M. avium 104 | MAV_2987 | - | 2e-13 | 28.40% (250) | NAD binding oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2613 | - | 3e-15 | 25.51% (294) | inositol 2-dehydrogenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2612 | - | 2e-17 | 28.10% (363) | putative oxidoreductase |
| M. marinum M | MMAR_2628 | - | 4e-13 | 27.17% (357) | hypothetical protein MMAR_2628 |
| M. smegmatis MC2 155 | MSMEG_3300 | - | 1e-25 | 29.75% (316) | oxidoreductase, Gfo/Idh/MocA family protein |
| M. thermoresistible (build 8) | TH_3104 | - | 9e-23 | 27.95% (347) | PUTATIVE oxidoreductase domain protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3968 | - | 9e-16 | 23.50% (349) | inositol 2-dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2613|M.gilvum_PYR-GCK ------MTSLGLIGL----GRIGAFHTETLINLPEVSRLVITDERPGVVG
Mvan_3968|M.vanbaalenii_PYR-1 ------MTTLGLIGL----GRIGAFHAETLTNLPEVSGLVVTDERPEVVS
MAV_1941|M.avium_104 -----MTLRVGIIGV----GWGAHVQVPGFRAAKGYEPVALCARTPERLE
TH_3104|M.thermoresistible__bu -------MRVLVIGT----GFGRQAMAPVYRGL-GFDVEVVSPRDESALH
MAB_2612|M.abscessus_ATCC_1997 ------MLKVGIIGA----GGVARAHARALNTLKSAELVGVLDIDARAAE
MSMEG_3300|M.smegmatis_MC2_155 ----MTPIGVGVIGASPNGGWAALAHVPALRALPEYDLRAVATSRPESAE
MMAR_2628|M.marinum_M MTGHGSPLRIGILGAAR---IAPQALVKPAQGNVEAVVAAVAARDGARAQ
: ::* . :
Mflv_2613|M.gilvum_PYR-GCK EVAAKYGATPVESVEKLLSS--GIDGVVVAAATPAHAELTLAAVERGLPT
Mvan_3968|M.vanbaalenii_PYR-1 QLATKYGATPANSVQELLAS--GVDGVIVAAATPAHAELTLAAVERGLPT
MAV_1941|M.avium_104 RVADKLGIEETSTDWESFVTRDDLDVISVATPTVLHRDMTLAALAAGKPV
TH_3104|M.thermoresistible__bu RALNAG-----------------VDLVSVHSPPFLHRQHVTAAVDRGYPV
MAB_2612|M.abscessus_ATCC_1997 SFTDAYGGTPVTDVDALLEL---ADAVVVASPNFTHRDHSLSALRAGRSV
MSMEG_3300|M.smegmatis_MC2_155 RAKVAWGVDAYHDPRRLVERR-DIDLVVVAVKVPDHYGLITDALTAGKAV
MMAR_2628|M.marinum_M AFAAKHGISRVHSSYEALIADPTLDAVYIPLPNGLHGRWTQAALTAGKHV
* : : * *: * .
Mflv_2613|M.gilvum_PYR-GCK FCEKPIASTAAESARVAEIIARSGVPVQVGYQRRFDTAFAAVKQAADSGS
Mvan_3968|M.vanbaalenii_PYR-1 FCEKPIAATAAESARVGEVITRSGVPVQVGYQRRFDAAFAAVKHAVDDGS
MAV_1941|M.avium_104 LCEKPLAGDLDAARDMVRAAAEANVPTACCFENRWNPDWLAVADRVRSGF
TH_3104|M.thermoresistible__bu LCDKPFGRNADEARAMRDHAARRAVPTFLNFELRHQPARAEFKKLADSGV
MAB_2612|M.abscessus_ATCC_1997 LCEKPLALSRVEAKEMVAAAGEIASPALVGFNYRHLPVVTELRRRLQHGD
MSMEG_3300|M.smegmatis_MC2_155 FSEWPLGVALEQAQILHAEAVVAGVPTVVGLQARFAPAIRRMRELVDAGY
MMAR_2628|M.marinum_M LCEKPFTANAAEADEIAQLAATTDRVVMEAFHYRYHPLTLRIEQILASGE
:.: *: : : . . * . . *
Mflv_2613|M.gilvum_PYR-GCK LGALHTVRSTTMDP--APPPMDYIRG--------SGGIFRDCAVHDFDVI
Mvan_3968|M.vanbaalenii_PYR-1 LGALHTVRSTTMDP--APPPMDYIKG--------SGGIFRDCAVHDFDVI
MAV_1941|M.avium_104 LGTQYLARVSRSAS--YWHPSHPLQAHWMYDREQGGGYLAGMLVHDLDFL
TH_3104|M.thermoresistible__bu IGTPRHLSWTFFGAGLRGRPHGWINE-----RDTGGGWIGANGAHLIDYT
MAB_2612|M.abscessus_ATCC_1997 FGTICAVELGFRKDSAYRRKNHTWRDSG--RSNGTSGALGDLGVHLLDLL
MSMEG_3300|M.smegmatis_MC2_155 VG--KVLSTNIVGSGMAWAPGAPAAQAYAFDARNGVTTLTVSTAHALDAL
MMAR_2628|M.marinum_M LGTLQRVETSMCFPLPKFSDIRYNYA-------LAGGATMDAGCYAVHMA
.* : ..
Mflv_2613|M.gilvum_PYR-GCK RWVTGQNVVEVYATG-SVQGDPLFTEYG-----DVDTAAIVVRFDGGALG
Mvan_3968|M.vanbaalenii_PYR-1 RWVTGQNVVDVYATG-SVQGDPRFAEYG-----DVDTAAVVVRFDGGALG
MAV_1941|M.avium_104 CSLLGRPVSVCAEVR-TSDPVRELPDGGTLHVTADDTAAVLMRMESGVTA
TH_3104|M.thermoresistible__bu RYLFGSEITGCGGVARIEDPHRPDPQGRPRRATAEDAYSAWFVTENGCTA
MAB_2612|M.abscessus_ATCC_1997 TYISGGRILVDECQARITTHVTNKSDEA---VEVDDHAEIYGRLSTGSIF
MSMEG_3300|M.smegmatis_MC2_155 SYVLG-DISSVTSTLGVGNDTITLDDGSTTTVTSPDQVAVTAQLESGAVA
MMAR_2628|M.marinum_M RTFGGGTPEVVSAQAKRRDSE------------VDRAMTAELRFPAGHSG
. * *
Mflv_2613|M.gilvum_PYR-GCK VVSAARYN-GRGYDCRLEVHGFDDTVVAG-------WDQGAPVRNADP--
Mvan_3968|M.vanbaalenii_PYR-1 VVSAARYN-GRGYDCRLEVHGFDDTVVAG-------WDQGAPVRNADPDF
MAV_1941|M.avium_104 VLSVSVMG-AHADHYRLELFGSDGTIIGDGDLRSAAYSLGAATDDGLRSL
TH_3104|M.thermoresistible__bu THDTAFAA-AVALPPRMVLTGSAGALELIG-------DSRLIVHRADADP
MAB_2612|M.abscessus_ATCC_1997 TLVASKAAPAADCGFSIRIVGTNAVFRYHTAD---PGRYLVSRGADTETV
MSMEG_3300|M.smegmatis_MC2_155 SVFYRGGL-SRAGNLRWEINGTHGDLLLTSPAPNGNIQATELVLAGANGS
MMAR_2628|M.marinum_M RIQCSMWS-SHLLNMSARVVGDRGELRVLN------PVVPQLFHRLTVQS
. : * .
Mflv_2613|M.gilvum_PYR-GCK --ANDFPTGQP--HHFFMDRFTEAFRTELSSFVDVVEGGPNLGATVADAV
Mvan_3968|M.vanbaalenii_PYR-1 SSPGAFPAGPP--HHFFMDRFTEAFRAELRAFVDVVEGGPIRGATVADAV
MAV_1941|M.avium_104 AVDEREPAHPDRLPRGLAGHASRAMALMLQDWLPAFDGAPSNVATFEDGL
TH_3104|M.thermoresistible__bu MTHEFPPAPPR-------SFYEPALTPWLEQVADALRTGRPATPSFDDGV
MAB_2612|M.abscessus_ATCC_1997 DLARTLLSDPDNEVHGWSDSFRSEIDHWSRLVAVGGGANRQALATFDDGL
MSMEG_3300|M.smegmatis_MC2_155 ATHLEPIHTHDAHPETGLSGPANTVANLYRAFAHDQLLGTAAAPTFGDAV
MMAR_2628|M.marinum_M AIGRRVERFPR----------RASYAYQLDAFTGAILRGEAVKTTPQDAV
.: *.:
Mflv_2613|M.gilvum_PYR-GCK EVAWIAEAATESLR-RGVPVTIDSVRKEAQQ-
Mvan_3968|M.vanbaalenii_PYR-1 EVAWIAEAATESLR-RGVPVTIESVRKETQQ-
MAV_1941|M.avium_104 LSLAIIDAARRSAE-GGGWEPVQA--------
TH_3104|M.thermoresistible__bu AVAEVMDRLRANVI-EQVMQ------------
MAB_2612|M.abscessus_ATCC_1997 AAQEVLESLLRGSKPQPERLPVEHTLPTPAEL
MSMEG_3300|M.smegmatis_MC2_155 ALHRLIAGIEHVNTESHRKY------------
MMAR_2628|M.marinum_M QNMTVIDAIYRAAGLPLRNPS-----------
: