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MSIHLHWYLPTNGDSREIVGAGDDSHLAVGPTASGMRPPTIDYLGEIARTAERLGFEAVLTPTGTRWEDA WITTAALSQTTTRLKFLVAFRPGFISPTLAAHQAATFQRISGGRLLLNIVAGGDPVEQARYGDHLDHDAR YRRTGEFLEVVRGVSTAPAGSAYDFDGEYYRITGARIDFGDWDPPQIFFGGASEAAEDVAAQHVDTYLAW GETPTQIAERLERMRTKAAAHGRTLRFGIRLHVISRDTSADAWTQAERLLSTISPERIASAQQVLARTES VGQQRMTALHDGGTSNLEISPNLWAGYGLVRGGAGTALVGSHTEVADRISEYHALGIDHFILSGQPHIEE AYWFAEGAGAILRDRGLL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4539 | - | - | 100% (368) | alkanesulfonate monooxygenase |
| M. smegmatis MC2 155 | MSMEG_3850 | - | e-118 | 59.28% (361) | alkanesulfonate monooxygenase family protein |
| M. smegmatis MC2 155 | MSMEG_2651 | - | e-105 | 53.64% (371) | alkanesulfonate monooxygenase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0965c | - | 1e-12 | 29.23% (195) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_5136 | - | 1e-107 | 53.21% (374) | alkanesulfonate monooxygenase |
| M. tuberculosis H37Rv | Rv0940c | - | 1e-12 | 29.23% (195) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 5e-07 | 32.35% (136) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_2219 | - | 1e-122 | 60.61% (363) | putative alkanesulfonate monooxygenase |
| M. marinum M | MMAR_4200 | fgd2 | 1e-110 | 56.13% (367) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. avium 104 | MAV_4628 | - | 1e-112 | 56.95% (367) | alkanesulfonate monoxygenase family protein |
| M. thermoresistible (build 8) | TH_3352 | - | 1e-106 | 53.87% (375) | PUTATIVE Alkanesulfonate monooxygenase |
| M. ulcerans Agy99 | MUL_4507 | fgd2 | 1e-109 | 55.86% (367) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. vanbaalenii PYR-1 | Mvan_1200 | - | 1e-107 | 53.48% (374) | alkanesulfonate monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0965c|M.bovis_AF2122/97 ----------------------------MRFSYAEAMTDFTFYIPLAKAA
Rv0940c|M.tuberculosis_H37Rv ----------------------------MRFSYAEAMTDFTFYIPLAKAA
MSMEG_4539|M.smegmatis_MC2_155 ----------------------------MSIHLHWYLPTNGDSREIVGAG
MAB_2219|M.abscessus_ATCC_1997 ----------------------------MAAKFFWFLPTNGDSRSIVGAS
MMAR_4200|M.marinum_M ----------------------------MALSFHWFLPTYGDSRGLVAGG
MUL_4507|M.ulcerans_Agy99 ----------------------------MALLFHWFLPTYGDSRGLVAGG
MAV_4628|M.avium_104 ----------------------------MSLAFHWFLPTYGDSRNLVAGG
Mflv_5136|M.gilvum_PYR-GCK --------------------------MTHAIKLHWFLPTYGDSRHIVGGG
Mvan_1200|M.vanbaalenii_PYR-1 MCTVAVLQIPLTQTADLPTPSGHHLVVTSAIKLHWFLPTYGDSRLIVGGG
TH_3352|M.thermoresistible__bu ----------------------------VTIKLHWFLPTYGDSRLIVGGG
MLBr_00348|M.leprae_Br4923 ---------------------------------------------MVERA
:. .
Mb0965c|M.bovis_AF2122/97 EAAGYSSMT-----IPDSIAYPFESDSKYPYTPDGNREFMDGKPFIETFV
Rv0940c|M.tuberculosis_H37Rv EAAGYSSMT-----IPDSIAYPFESDSKYPYTPDGNREFMDGKPFIETFV
MSMEG_4539|M.smegmatis_MC2_155 DDSHLAVGPTASGMRPPTIDYLGEIARTAERLGFEAVLTPTGTRWEDAWI
MAB_2219|M.abscessus_ATCC_1997 HASTHHTVP--EGYREPSLRYLGEVARAADRLGFEGVLTPTGTWCEDAWL
MMAR_4200|M.marinum_M HGLPMS------GNRPATLRYLNQIAAAAESNGFEAVLTPAGLWCEDAWL
MUL_4507|M.ulcerans_Agy99 HGLPMS------GNRPATLRYLNQIAAAAESNGFEAVLTPAGLWCEDAWL
MAV_4628|M.avium_104 HGTPMS------GDRPATLRYLHQICSAAEDNGFEAVLTPTGLWCEDAWL
Mflv_5136|M.gilvum_PYR-GCK HGTPAGSAH---SDRDASIDYLASIVRAAETFGFTGALIPTGAWCEDAFI
Mvan_1200|M.vanbaalenii_PYR-1 HGTPAGAAR---GDRDASIDYLASIVRAAETFGFTGALIPTGAWCEDAFI
TH_3352|M.thermoresistible__bu HGTPAGAAG---GDRDASIDYLASIVRAAETFGFTGALIPTGAWCEDAFI
MLBr_00348|M.leprae_Br4923 NAMKLGLQLG--YWAAQPPGNAAELVAAAEGAGFDAVFTG-EAWGSDAYT
. . . :::
Mb0965c|M.bovis_AF2122/97 LTAALGAVTTRLRFNFFVLKLPIRPPALVAKQAGSLAALIGNRVGLGVGT
Rv0940c|M.tuberculosis_H37Rv LTAALGAVTTRLRFNFFVLKLPIRPPALVAKQAGSLAALIGNRVGLGVGT
MSMEG_4539|M.smegmatis_MC2_155 TTAALSQTTTRLKF-LVAFRPGFISPTLAAHQAATFQRISGGRLLLNIVA
MAB_2219|M.abscessus_ATCC_1997 TAAGLLDQTERLKF-LVAFRPGLVPPTLAAQQAATLQRFSNGRLLLNVVS
MMAR_4200|M.marinum_M TTAMLVGTTETLKF-LVALRPGLVSPTLAAQMATTFQQQSGGRLLLNVVT
MUL_4507|M.ulcerans_Agy99 TTAMLVGTTKTLKF-LVALRPGLVSPTLAAQMATTFQQQSGGRLLVNVVT
MAV_4628|M.avium_104 TTAMLVESTETLKF-LVAFRPGLLSPTLAAQMAGTFQRHSQGRLLLNVVT
Mflv_5136|M.gilvum_PYR-GCK TAALLARETSTLGF-LVAFRPGLVSPTLSAQMAATFARHAPGRLLLNVVV
Mvan_1200|M.vanbaalenii_PYR-1 TAALLARETTSLAF-LVAFRPGLVSPTLSAQMAATFARHAPGRILLNVVV
TH_3352|M.thermoresistible__bu TAALLARETTSLGF-LVAFRPGLVSPTLSAQMAATFARHAPGRILLNVVV
MLBr_00348|M.leprae_Br4923 PLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGLGV
* * : : ..: .*: * * :: .* :.:
Mb0965c|M.bovis_AF2122/97 SPWPEDYELMGVPFAK--RGKRIDECIEIVRGLTTG---DYFEFHGEFYD
Rv0940c|M.tuberculosis_H37Rv SPWPEDYELMGVPFAK--RGKRIDECIEIVRGLTTG---DYFEFHGEFYD
MSMEG_4539|M.smegmatis_MC2_155 GGDPVEQARYGDHLDHDARYRRTGEFLEVVRGVSTAPAGSAYDFDGEYYR
MAB_2219|M.abscessus_ATCC_1997 GGDDAEQRRFGDWLTHDERYERTGEFLQIVRDIWR---GSPVDFSGKHYT
MMAR_4200|M.marinum_M GGEAHEQRAYGDFLDKQQRYRRTGEFLHVVRQLWASG--QPVTFEGEHIH
MUL_4507|M.ulcerans_Agy99 GGEAHEQRAYGDFLDKQQRYRRTGEFLHVVRQLWASG--QPVTFEGEHIH
MAV_4628|M.avium_104 GGEPHEQRAYGDFLDKEARYARTAEFLHVVRQLWTSP--QPVTFAGEHIR
Mflv_5136|M.gilvum_PYR-GCK GGEAHEQRSFGDHLDKDGRYARADEFLDVVRRLWDG---QTVSLDGEHIR
Mvan_1200|M.vanbaalenii_PYR-1 GGEAHEQRSFGDYLDKEGRYARADEFLDVVRRLWDG---QTVTLDGEHIR
TH_3352|M.thermoresistible__bu GGESHEQRAFGDHLDKDERYRRADEFLEVVRRLWAG---ETVTLHGRHIR
MLBr_00348|M.leprae_Br4923 SGPQVVEGWYGQPFPKP--LSRTREYIDIVRQVWAR--EAPVVSDGQHYP
. * : : * * :.:** : *..
Mb0965c|M.bovis_AF2122/97 IPKT------------KMTPAPTQPIPILVGGHADAALRRAAR-ADGWMH
Rv0940c|M.tuberculosis_H37Rv IPKT------------KMTPAPTQPIPILVGGHADAALRRAAR-ADGWMH
MSMEG_4539|M.smegmatis_MC2_155 ITGA------------RIDFGDWDPPQIFFGGASEAAEDVAAQHVDTYLA
MAB_2219|M.abscessus_ATCC_1997 VTDA------------RVSEPPSPLPELYFGGSSPAALPIAADHVDVYLT
MMAR_4200|M.marinum_M VHQA------------QLGRLPDPPPPVFFGGSSESAGAVAARYADTYLT
MUL_4507|M.ulcerans_Agy99 VHQA------------QLGRLPDPPPPVFFGGSSESAGAVAARYADTYLT
MAV_4628|M.avium_104 VEGA------------QLNNPPDPIPAVFFGGSSASAGPVAAKHSDVYLT
Mflv_5136|M.gilvum_PYR-GCK VENA------------SLPTVPAPVPPLYFGGSSAAAGPVAARHADVYLT
Mvan_1200|M.vanbaalenii_PYR-1 VEGA------------SLATLPDPAPPLYFGGSSAAAGPVAARHADVYLT
TH_3352|M.thermoresistible__bu VEDA------------ALPTLPDPVPPLYFGGSSTAAGPVAARHADVYLT
MLBr_00348|M.leprae_Br4923 LPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLP
: : : : .*. . ** * ::
Mb0965c|M.bovis_AF2122/97 GGGDPDELDRLIARVKR-LREEAGKTSPFEIHVISLDGFTVDG-------
Rv0940c|M.tuberculosis_H37Rv GGGDPDELDRLIARVKR-LREEAGKTSPFEIHVISLDGFTVDG-------
MSMEG_4539|M.smegmatis_MC2_155 WGETPTQIAERLERMRT-KAAAHGRTLRFGIRLHVISRDTSADAWTQAER
MAB_2219|M.abscessus_ATCC_1997 WGEPPAAAAAKIEAVRA-LAKERGRTLRFGIRLHTISRDTSEAAWAVANS
MMAR_4200|M.marinum_M WGEPLSAVGKKIDWIRG-LAADHGRALSYGLRIHVITRDTAEEAWRVADR
MUL_4507|M.ulcerans_Agy99 WGEPLSAVGKKIDWIRG-LAADHGRALSYGLRIHVITRDTAEEAWRVADR
MAV_4628|M.avium_104 WGEPLTAVAKKLDWVRG-LAVDAGRILQYGLRIHVISRDTSAAAWAEADR
Mflv_5136|M.gilvum_PYR-GCK WGEPPAAVAEKVEWIRR-AAAGQGRQLRFGIRLHVITRDTAGAAWAEADR
Mvan_1200|M.vanbaalenii_PYR-1 WGEPPAAVADKVDWIRR-LAAKQGRQVRFGIRLHVITRDAADEAWSQADK
TH_3352|M.thermoresistible__bu WGEPPDAVREKIDWIRT-LAAAEGRRVRFGIRLHTISRDTADEAWAQADK
MLBr_00348|M.leprae_Br4923 IFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDRAAAFA
: .: :.: .
Mb0965c|M.bovis_AF2122/97 -VKRLEDKGVTDVIVGFRVPYTMG--------------------------
Rv0940c|M.tuberculosis_H37Rv -VKRLEDKGVTDVIVGFRVPYTMG--------------------------
MSMEG_4539|M.smegmatis_MC2_155 LLSTISPERIASAQQVLARTESVGQQRMTALHDGGTSN--------LEIS
MAB_2219|M.abscessus_ATCC_1997 LVGELTPDQIAKATALHSKSESEGQRRMTALHGGRLDK--------LEIY
MMAR_4200|M.marinum_M LLAGIDPADIERMQANLARSESEGQRRMAELHGGALDQ--------LEIA
MUL_4507|M.ulcerans_Agy99 LLAGIDPADIERMQANLARSESEGQRRMAELHGGVLDQ--------LEIA
MAV_4628|M.avium_104 LLSAIDPADIERVQASLARSESEGQRRMRELHGGDSGK--------LLVG
Mflv_5136|M.gilvum_PYR-GCK LVGALDDETVRNAQEGLGRSQSEGQRRMSALHQAHRANGSWHDARTLEVA
Mvan_1200|M.vanbaalenii_PYR-1 LVSALDDETVRSAQAGLGRSQSEGQRRMLALHEAHRADGSWHDARSLEIA
TH_3352|M.thermoresistible__bu LIGALDEHTVRAAQAGLRRSESEGQRRMLALHQANRADGSWRSARSLEVA
MLBr_00348|M.leprae_Br4923 GIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFR-----SNQ
: : : :
Mb0965c|M.bovis_AF2122/97 -------------PDTEPLQTKIRNLEMFAENVIAKV-------------
Rv0940c|M.tuberculosis_H37Rv -------------PDTEPLQTKIRNLEMFAENVIAKV-------------
MSMEG_4539|M.smegmatis_MC2_155 PNLWAGYGLVRGGAGTALVGSHTEVADRISEYHALGIDHFILSGQPHIEE
MAB_2219|M.abscessus_ATCC_1997 PNLWAGVGLVRGGAGTALVGSHEEVANLISEYHALGFDEFILSGYPHLEE
MMAR_4200|M.marinum_M PNLWAGVGLVRGGAGTALVGSHQEVAERIIEYARLGISHFILSGYPHLEE
MUL_4507|M.ulcerans_Agy99 PNLWAGVGLVRGGAGTALVGSHQEVAERIIEYARLGISHFILSGYPHLEE
MAV_4628|M.avium_104 PNLWAGVGLVRGGAGTALVGSHAEVAERLAEYAKLGITHFILSGYPHLEE
Mflv_5136|M.gilvum_PYR-GCK PNLWTGVGLVRGGAGTALVGSHSEVADRIAEYAEVGIDEFIFSGYPHLEE
Mvan_1200|M.vanbaalenii_PYR-1 PNLWAGVGLVRGGAGTALVGSHTEVADRIAEYAEAGIDEFVFSGYPHLEE
TH_3352|M.thermoresistible__bu PNLWAGVGLVRGGAGTALVGSHAEVADRIAEYAAAGIEEFIFSGYPHLEE
MLBr_00348|M.leprae_Br4923 KDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVS-------
.* : . : .
Mb0965c|M.bovis_AF2122/97 ------------------------------------------
Rv0940c|M.tuberculosis_H37Rv ------------------------------------------
MSMEG_4539|M.smegmatis_MC2_155 AYWFAEGAGAILRDRGLL------------------------
MAB_2219|M.abscessus_ATCC_1997 AYWFAEGVLPLLKKRGALAA----------------------
MMAR_4200|M.marinum_M AYWFGEGVLPILERKRLWHRPHGSSPHSAALPVAHSSVN---
MUL_4507|M.ulcerans_Agy99 AYWFGEGVLPILERKRLWHRPHGSSPHSAALPVAHSSVN---
MAV_4628|M.avium_104 AYWFGEGVLPLLERMGLWRHPNRRSRPAATTPFAVASAH---
Mflv_5136|M.gilvum_PYR-GCK LYWLGEGVVPLLRERGLFE-AGPKQAASASIPFVGGTGRGRI
Mvan_1200|M.vanbaalenii_PYR-1 LFWFGEGVVPILRDRGLFT-ADVKGAAASSIPFVGAAR----
TH_3352|M.thermoresistible__bu LFWFGEGVVPILRSRNLFDGAGDRSPVPAAIPFVGAAR----
MLBr_00348|M.leprae_Br4923 ----ASSVEQVRDLAGLF------------------------