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LAAKFFWFLPTNGDSRSIVGASHASTHHTVPEGYREPSLRYLGEVARAADRLGFEGVLTPTGTWCEDAWL TAAGLLDQTERLKFLVAFRPGLVPPTLAAQQAATLQRFSNGRLLLNVVSGGDDAEQRRFGDWLTHDERYE RTGEFLQIVRDIWRGSPVDFSGKHYTVTDARVSEPPSPLPELYFGGSSPAALPIAADHVDVYLTWGEPPA AAAAKIEAVRALAKERGRTLRFGIRLHTISRDTSEAAWAVANSLVGELTPDQIAKATALHSKSESEGQRR MTALHGGRLDKLEIYPNLWAGVGLVRGGAGTALVGSHEEVANLISEYHALGFDEFILSGYPHLEEAYWFA EGVLPLLKKRGALAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2219 | - | - | 100% (365) | putative alkanesulfonate monooxygenase |
| M. abscessus ATCC 19977 | MAB_1060 | - | 8e-34 | 32.04% (334) | putative alkanesulfonate monooxygenase |
| M. abscessus ATCC 19977 | MAB_4125 | - | 7e-14 | 26.55% (388) | putative nitrilotriacetate monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1886c | - | 2e-10 | 31.13% (212) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_5136 | - | 1e-115 | 57.26% (372) | alkanesulfonate monooxygenase |
| M. tuberculosis H37Rv | Rv1855c | - | 2e-10 | 31.13% (212) | oxidoreductase |
| M. leprae Br4923 | MLBr_00269 | - | 3e-08 | 27.13% (129) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. marinum M | MMAR_4200 | fgd2 | 1e-119 | 58.45% (361) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. avium 104 | MAV_4628 | - | 1e-122 | 59.67% (362) | alkanesulfonate monoxygenase family protein |
| M. smegmatis MC2 155 | MSMEG_3850 | - | 1e-174 | 79.73% (365) | alkanesulfonate monooxygenase family protein |
| M. thermoresistible (build 8) | TH_3352 | - | 1e-116 | 58.90% (365) | PUTATIVE Alkanesulfonate monooxygenase |
| M. ulcerans Agy99 | MUL_4507 | fgd2 | 1e-117 | 57.89% (361) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. vanbaalenii PYR-1 | Mvan_1200 | - | 1e-114 | 56.72% (372) | alkanesulfonate monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2219|M.abscessus_ATCC_1997 ----------------------------MAAKFFWFLPTNGDSRSIVGAS
MSMEG_3850|M.smegmatis_MC2_155 ---------------------------MTFAKFFWFLPTAGDSRGIVGSS
Mflv_5136|M.gilvum_PYR-GCK --------------------------MTHAIKLHWFLPTYGDSRHIVGGG
Mvan_1200|M.vanbaalenii_PYR-1 MCTVAVLQIPLTQTADLPTPSGHHLVVTSAIKLHWFLPTYGDSRLIVGGG
TH_3352|M.thermoresistible__bu ----------------------------VTIKLHWFLPTYGDSRLIVGGG
MMAR_4200|M.marinum_M ----------------------------MALSFHWFLPTYGDSRGLVAGG
MUL_4507|M.ulcerans_Agy99 ----------------------------MALLFHWFLPTYGDSRGLVAGG
MAV_4628|M.avium_104 ----------------------------MSLAFHWFLPTYGDSRNLVAGG
Mb1886c|M.bovis_AF2122/97 ----------------------------MTIRLGLQIPNFS-----YGTG
Rv1855c|M.tuberculosis_H37Rv ----------------------------MTIRLGLQIPNFS-----YGTG
MLBr_00269|M.leprae_Br4923 ---------------------------MAELRLGYKA-----------SA
: .
MAB_2219|M.abscessus_ATCC_1997 HASTHHTVPEGYREPSLRYLGEVARAADRLGFEGVLTPTGTWCEDAWLTA
MSMEG_3850|M.smegmatis_MC2_155 HASSQHSVPDNYRAPTRRYLAEVARAADRLGYEGVLTPTGTWCEDAWLTT
Mflv_5136|M.gilvum_PYR-GCK HG-TPAGSAHSDRDASIDYLASIVRAAETFGFTGALIPTGAWCEDAFITA
Mvan_1200|M.vanbaalenii_PYR-1 HG-TPAGAARGDRDASIDYLASIVRAAETFGFTGALIPTGAWCEDAFITA
TH_3352|M.thermoresistible__bu HG-TPAGAAGGDRDASIDYLASIVRAAETFGFTGALIPTGAWCEDAFITA
MMAR_4200|M.marinum_M HG-LPMS---GNRPATLRYLNQIAAAAESNGFEAVLTPAGLWCEDAWLTT
MUL_4507|M.ulcerans_Agy99 HG-LPMS---GNRPATLRYLNQIAAAAESNGFEAVLTPAGLWCEDAWLTT
MAV_4628|M.avium_104 HG-TPMS---GDRPATLRYLHQICSAAEDNGFEAVLTPTGLWCEDAWLTT
Mb1886c|M.bovis_AF2122/97 VEKLFPSVIAQAREAEAAGYDSLFVMDHFYQLPMLGTPD-QPMLEAYTAL
Rv1855c|M.tuberculosis_H37Rv VEKLFPSVIAQAREAEAAGYDSLFVMDHFYQLPMLGTPD-QPMLEAYTAL
MLBr_00269|M.leprae_Br4923 EQFAPRELVELGVAAEAHGMDSATVSDHFQPWR----HQGGHASFSLSWM
. . . :
MAB_2219|M.abscessus_ATCC_1997 AGLLDQTERLKFLVAFR-PGLVP-PTLAAQQAATLQRFSNGRLLLNVVSG
MSMEG_3850|M.smegmatis_MC2_155 SALLAETERLKFLVAFR-PGLMP-PTLAAQQAATLQRFSEGRVLLNIVTG
Mflv_5136|M.gilvum_PYR-GCK ALLARETSTLGFLVAFR-PGLVS-PTLSAQMAATFARHAPGRLLLNVVVG
Mvan_1200|M.vanbaalenii_PYR-1 ALLARETTSLAFLVAFR-PGLVS-PTLSAQMAATFARHAPGRILLNVVVG
TH_3352|M.thermoresistible__bu ALLARETTSLGFLVAFR-PGLVS-PTLSAQMAATFARHAPGRILLNVVVG
MMAR_4200|M.marinum_M AMLVGTTETLKFLVALR-PGLVS-PTLAAQMATTFQQQSGGRLLLNVVTG
MUL_4507|M.ulcerans_Agy99 AMLVGTTKTLKFLVALR-PGLVS-PTLAAQMATTFQQQSGGRLLVNVVTG
MAV_4628|M.avium_104 AMLVESTETLKFLVAFR-PGLLS-PTLAAQMAGTFQRHSQGRLLLNVVTG
Mb1886c|M.bovis_AF2122/97 GALATATERLQLGALVTGNTYRS-PTLLAKIITTLDVVSAGRAILGIGAG
Rv1855c|M.tuberculosis_H37Rv GALATATERLQLGALVTGNTYRS-PTLLAKIITTLDVVSAGRAILGIGAG
MLBr_00269|M.leprae_Br4923 TAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLYPNRVFLGVGTG
: * : : . . *:: .: *: .* ::.: *
MAB_2219|M.abscessus_ATCC_1997 GDDAEQR-RFG-DWLTHDERYERTGEFLQIVRDIWRGS---PVDFSGKHY
MSMEG_3850|M.smegmatis_MC2_155 GDNVEQR-RFG-DWLDHDERYARTGEFLHIVNRLWRQSGDESLDYEGTYY
Mflv_5136|M.gilvum_PYR-GCK GEAHEQR-SFG-DHLDKDGRYARADEFLDVVRRLWDG---QTVSLDGEHI
Mvan_1200|M.vanbaalenii_PYR-1 GEAHEQR-SFG-DYLDKEGRYARADEFLDVVRRLWDG---QTVTLDGEHI
TH_3352|M.thermoresistible__bu GESHEQR-AFG-DHLDKDERYRRADEFLEVVRRLWAG---ETVTLHGRHI
MMAR_4200|M.marinum_M GEAHEQR-AYG-DFLDKQQRYRRTGEFLHVVRQLWASG--QPVTFEGEHI
MUL_4507|M.ulcerans_Agy99 GEAHEQR-AYG-DFLDKQQRYRRTGEFLHVVRQLWASG--QPVTFEGEHI
MAV_4628|M.avium_104 GEPHEQR-AYG-DFLDKEARYARTAEFLHVVRQLWTSP--QPVTFAGEHI
Mb1886c|M.bovis_AF2122/97 WFELEHR-QLGFEFGTFSDRFNRLEEALQILEPMVKGE--RPTFFGDWYT
Rv1855c|M.tuberculosis_H37Rv WFELEHR-QLGFEFGTFSDRFNRLEEALQILEPMVKGE--RPTFFGDWYT
MLBr_00269|M.leprae_Br4923 EALNEVATGYQGAWPEFKERFARLRESVRLMRELWRGD---RVDFDGDYY
* . *: * * : ::. : . :
MAB_2219|M.abscessus_ATCC_1997 TVTDARVSEPPSPLPELYFGGSSPAALPIAADHVDVYLTWGEPPAAAAAK
MSMEG_3850|M.smegmatis_MC2_155 NVADARVSAPPDPLPQIYFGGSSPAAMPIAAEHVDVYLTWGEPPQDAAAK
Mflv_5136|M.gilvum_PYR-GCK RVENASLPTVPAPVPPLYFGGSSAAAGPVAARHADVYLTWGEPPAAVAEK
Mvan_1200|M.vanbaalenii_PYR-1 RVEGASLATLPDPAPPLYFGGSSAAAGPVAARHADVYLTWGEPPAAVADK
TH_3352|M.thermoresistible__bu RVEDAALPTLPDPVPPLYFGGSSTAAGPVAARHADVYLTWGEPPDAVREK
MMAR_4200|M.marinum_M HVHQAQLGRLPDPPPPVFFGGSSESAGAVAARYADTYLTWGEPLSAVGKK
MUL_4507|M.ulcerans_Agy99 HVHQAQLGRLPDPPPPVFFGGSSESAGAVAARYADTYLTWGEPLSAVGKK
MAV_4628|M.avium_104 RVEGAQLNNPPDPIPAVFFGGSSASAGPVAAKHSDVYLTWGEPLTAVAKK
Mb1886c|M.bovis_AF2122/97 TESAMAEPRYRDRIPILIGGGGEKKTFAIAARFAD-HLNIVAAVDELPRK
Rv1855c|M.tuberculosis_H37Rv TESAMAEPRYRDRIPILIGGGGEKKTFAIAARFAD-HLNIVAAVDELPRK
MLBr_00269|M.leprae_Br4923 QLKGASIYDVPEGGVPIYIAAGGPEVAKYAGRAGEGFVCTSGKGEELYTE
: ... . *. : .: :
MAB_2219|M.abscessus_ATCC_1997 IEAVRALAKERGRTLRFGIRLHTISRDTSEAAWAVANSLVGELTPDQIAK
MSMEG_3850|M.smegmatis_MC2_155 IARVRALAEERGRTVRFGIRLHTISRDTSAAAWAVAHDMVAGLDPEAIAK
Mflv_5136|M.gilvum_PYR-GCK VEWIRRAAAGQGRQLRFGIRLHVITRDTAGAAWAEADRLVGALDDETVRN
Mvan_1200|M.vanbaalenii_PYR-1 VDWIRRLAAKQGRQVRFGIRLHVITRDAADEAWSQADKLVSALDDETVRS
TH_3352|M.thermoresistible__bu IDWIRTLAAAEGRRVRFGIRLHTISRDTADEAWAQADKLIGALDEHTVRA
MMAR_4200|M.marinum_M IDWIRGLAADHGRALSYGLRIHVITRDTAEEAWRVADRLLAGIDPADIER
MUL_4507|M.ulcerans_Agy99 IDWIRGLAADHGRALSYGLRIHVITRDTAEEAWRVADRLLAGIDPADIER
MAV_4628|M.avium_104 LDWVRGLAVDAGRILQYGLRIHVISRDTSAAAWAEADRLLSAIDPADIER
Mb1886c|M.bovis_AF2122/97 MRALAARCDEAGR-----------DRSTLQTSLLLTVMIDETLSPDAIPA
Rv1855c|M.tuberculosis_H37Rv MRALAARCDEAGR-----------DRSTLQTSLLLTVMIDETLSPDAIPA
MLBr_00269|M.leprae_Br4923 KLIPAVLEGAAVAG-----------RDADDIDKMIEIKMSYDPDPEQALS
*.: :
MAB_2219|M.abscessus_ATCC_1997 ATALHSKSESEGQRRMTALHGGRLDK--------LEIYPNLWAGVGLVRG
MSMEG_3850|M.smegmatis_MC2_155 ATALHSKSESEGQRRMTALHGGRTDK--------LEIYPNLWAGVGLVRG
Mflv_5136|M.gilvum_PYR-GCK AQEGLGRSQSEGQRRMSALHQAHRANGSWHDARTLEVAPNLWTGVGLVRG
Mvan_1200|M.vanbaalenii_PYR-1 AQAGLGRSQSEGQRRMLALHEAHRADGSWHDARSLEIAPNLWAGVGLVRG
TH_3352|M.thermoresistible__bu AQAGLRRSESEGQRRMLALHQANRADGSWRSARSLEVAPNLWAGVGLVRG
MMAR_4200|M.marinum_M MQANLARSESEGQRRMAELHGGALDQ--------LEIAPNLWAGVGLVRG
MUL_4507|M.ulcerans_Agy99 MQANLARSESEGQRRMAELHGGVLDQ--------LEIAPNLWAGVGLVRG
MAV_4628|M.avium_104 VQASLARSESEGQRRMRELHGGDSGK--------LLVGPNLWAGVGLVRG
Mb1886c|M.bovis_AF2122/97 EMS-----------------------------------------------
Rv1855c|M.tuberculosis_H37Rv EMS-----------------------------------------------
MLBr_00269|M.leprae_Br4923 NIRFWAPLSLAAEQKHSIDDPIEMEK--------------VADALPIEQV
MAB_2219|M.abscessus_ATCC_1997 GAGTALVGSHEEVANLI-SEYHALGFDEFILSG--YPHLEEAYWFAEGVL
MSMEG_3850|M.smegmatis_MC2_155 GAGTALVGSHEEVANLI-YEYHSLGFDEFILSG--YPHLEESYWFAEGVL
Mflv_5136|M.gilvum_PYR-GCK GAGTALVGSHSEVADRI-AEYAEVGIDEFIFSG--YPHLEELYWLGEGVV
Mvan_1200|M.vanbaalenii_PYR-1 GAGTALVGSHTEVADRI-AEYAEAGIDEFVFSG--YPHLEELFWFGEGVV
TH_3352|M.thermoresistible__bu GAGTALVGSHAEVADRI-AEYAAAGIEEFIFSG--YPHLEELFWFGEGVV
MMAR_4200|M.marinum_M GAGTALVGSHQEVAERI-IEYARLGISHFILSG--YPHLEEAYWFGEGVL
MUL_4507|M.ulcerans_Agy99 GAGTALVGSHQEVAERI-IEYARLGISHFILSG--YPHLEEAYWFGEGVL
MAV_4628|M.avium_104 GAGTALVGSHAEVAERL-AEYAKLGITHFILSG--YPHLEEAYWFGEGVL
Mb1886c|M.bovis_AF2122/97 --GRVVVGSPAQIADQIQAKVLDAGVDGLIINL--APHGYLPGVITTAAE
Rv1855c|M.tuberculosis_H37Rv --GRVVVGSPAQIADQIQAKVLDAGVDGLIINL--APHGYLPGVITTAAE
MLBr_00269|M.leprae_Br4923 AKRWIVVSDPDEAVARV-GQYVTWGLNHLVFHAPGHNQRRFLELFEKDLA
:*.. : . : : *. ::: : :
MAB_2219|M.abscessus_ATCC_1997 PLLKKRGALAA----------------------
MSMEG_3850|M.smegmatis_MC2_155 PILRRKGVAA-----------------------
Mflv_5136|M.gilvum_PYR-GCK PLLRERGLFE-AGPKQAASASIPFVGGTGRGRI
Mvan_1200|M.vanbaalenii_PYR-1 PILRDRGLFT-ADVKGAAASSIPFVGAAR----
TH_3352|M.thermoresistible__bu PILRSRNLFDGAGDRSPVPAAIPFVGAAR----
MMAR_4200|M.marinum_M PILERKRLWHRPHGSSPHSAALPVAHSSVN---
MUL_4507|M.ulcerans_Agy99 PILERKRLWHRPHGSSPHSAALPVAHSSVN---
MAV_4628|M.avium_104 PLLERMGLWRHPNRRSRPAATTPFAVASAH---
Mb1886c|M.bovis_AF2122/97 ALRPLLGV-------------------------
Rv1855c|M.tuberculosis_H37Rv ALRPLLGV-------------------------
MLBr_00269|M.leprae_Br4923 PRLRRLG--------------------------
.