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TFAKFFWFLPTAGDSRGIVGSSHASSQHSVPDNYRAPTRRYLAEVARAADRLGYEGVLTPTGTWCEDAWL TTSALLAETERLKFLVAFRPGLMPPTLAAQQAATLQRFSEGRVLLNIVTGGDNVEQRRFGDWLDHDERYA RTGEFLHIVNRLWRQSGDESLDYEGTYYNVADARVSAPPDPLPQIYFGGSSPAAMPIAAEHVDVYLTWGE PPQDAAAKIARVRALAEERGRTVRFGIRLHTISRDTSAAAWAVAHDMVAGLDPEAIAKATALHSKSESEG QRRMTALHGGRTDKLEIYPNLWAGVGLVRGGAGTALVGSHEEVANLIYEYHSLGFDEFILSGYPHLEESY WFAEGVLPILRRKGVAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3850 | - | - | 100% (368) | alkanesulfonate monooxygenase family protein |
| M. smegmatis MC2 155 | MSMEG_4539 | - | e-118 | 59.28% (361) | alkanesulfonate monooxygenase |
| M. smegmatis MC2 155 | MSMEG_2651 | - | e-117 | 58.31% (367) | alkanesulfonate monooxygenase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0965c | - | 1e-11 | 32.04% (181) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_5136 | - | 1e-110 | 54.32% (370) | alkanesulfonate monooxygenase |
| M. tuberculosis H37Rv | Rv0940c | - | 1e-11 | 32.04% (181) | oxidoreductase |
| M. leprae Br4923 | MLBr_00269 | - | 9e-07 | 31.00% (100) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2219 | - | 1e-174 | 79.73% (365) | putative alkanesulfonate monooxygenase |
| M. marinum M | MMAR_4200 | fgd2 | 1e-117 | 57.38% (359) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. avium 104 | MAV_4628 | - | 1e-120 | 57.89% (361) | alkanesulfonate monoxygenase family protein |
| M. thermoresistible (build 8) | TH_3352 | - | 1e-112 | 56.22% (370) | PUTATIVE Alkanesulfonate monooxygenase |
| M. ulcerans Agy99 | MUL_4507 | fgd2 | 1e-116 | 56.82% (359) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. vanbaalenii PYR-1 | Mvan_1200 | - | 1e-110 | 55.14% (370) | alkanesulfonate monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0965c|M.bovis_AF2122/97 -------------------------------MRFSYAEAMTDFTFYIPLA
Rv0940c|M.tuberculosis_H37Rv -------------------------------MRFSYAEAMTDFTFYIPLA
MSMEG_3850|M.smegmatis_MC2_155 ---------------------------MTFAKFFWFLPTAGDSRGIVGSS
MAB_2219|M.abscessus_ATCC_1997 ----------------------------MAAKFFWFLPTNGDSRSIVGAS
Mflv_5136|M.gilvum_PYR-GCK --------------------------MTHAIKLHWFLPTYGDSRHIVGGG
Mvan_1200|M.vanbaalenii_PYR-1 MCTVAVLQIPLTQTADLPTPSGHHLVVTSAIKLHWFLPTYGDSRLIVGGG
TH_3352|M.thermoresistible__bu ----------------------------VTIKLHWFLPTYGDSRLIVGGG
MMAR_4200|M.marinum_M ----------------------------MALSFHWFLPTYGDSRGLVAGG
MUL_4507|M.ulcerans_Agy99 ----------------------------MALLFHWFLPTYGDSRGLVAGG
MAV_4628|M.avium_104 ----------------------------MSLAFHWFLPTYGDSRNLVAGG
MLBr_00269|M.leprae_Br4923 ------------------------------------------MAELRLGY
Mb0965c|M.bovis_AF2122/97 KAAEAAGYSSMTIPDSIAYPFESDSKYPYTPDGNREFMDGKPFIETFVLT
Rv0940c|M.tuberculosis_H37Rv KAAEAAGYSSMTIPDSIAYPFESDSKYPYTPDGNREFMDGKPFIETFVLT
MSMEG_3850|M.smegmatis_MC2_155 HASSQHSVPDNYRAPTRRYLAEVARAADRLGYEGVLTPTGTWCEDAWLTT
MAB_2219|M.abscessus_ATCC_1997 HASTHHTVPEGYREPSLRYLGEVARAADRLGFEGVLTPTGTWCEDAWLTA
Mflv_5136|M.gilvum_PYR-GCK HG-TPAGSAHSDRDASIDYLASIVRAAETFGFTGALIPTGAWCEDAFITA
Mvan_1200|M.vanbaalenii_PYR-1 HG-TPAGAARGDRDASIDYLASIVRAAETFGFTGALIPTGAWCEDAFITA
TH_3352|M.thermoresistible__bu HG-TPAGAAGGDRDASIDYLASIVRAAETFGFTGALIPTGAWCEDAFITA
MMAR_4200|M.marinum_M HG-LPMS---GNRPATLRYLNQIAAAAESNGFEAVLTPAGLWCEDAWLTT
MUL_4507|M.ulcerans_Agy99 HG-LPMS---GNRPATLRYLNQIAAAAESNGFEAVLTPAGLWCEDAWLTT
MAV_4628|M.avium_104 HG-TPMS---GDRPATLRYLHQICSAAEDNGFEAVLTPTGLWCEDAWLTT
MLBr_00269|M.leprae_Br4923 KASAEQFAPRELVELGVAAEAHGMDSATVSDHFQPWRHQGGHASFSLSWM
:. * :
Mb0965c|M.bovis_AF2122/97 AALGAVTTRLRFNFFVLKLPIRP-PALVAKQAGSLAALIGNRVGLGVGTS
Rv0940c|M.tuberculosis_H37Rv AALGAVTTRLRFNFFVLKLPIRP-PALVAKQAGSLAALIGNRVGLGVGTS
MSMEG_3850|M.smegmatis_MC2_155 SALLAETERLKF-LVAFRPGLMP-PTLAAQQAATLQRFSEGRVLLNIVTG
MAB_2219|M.abscessus_ATCC_1997 AGLLDQTERLKF-LVAFRPGLVP-PTLAAQQAATLQRFSNGRLLLNVVSG
Mflv_5136|M.gilvum_PYR-GCK ALLARETSTLGF-LVAFRPGLVS-PTLSAQMAATFARHAPGRLLLNVVVG
Mvan_1200|M.vanbaalenii_PYR-1 ALLARETTSLAF-LVAFRPGLVS-PTLSAQMAATFARHAPGRILLNVVVG
TH_3352|M.thermoresistible__bu ALLARETTSLGF-LVAFRPGLVS-PTLSAQMAATFARHAPGRILLNVVVG
MMAR_4200|M.marinum_M AMLVGTTETLKF-LVALRPGLVS-PTLAAQMATTFQQQSGGRLLLNVVTG
MUL_4507|M.ulcerans_Agy99 AMLVGTTKTLKF-LVALRPGLVS-PTLAAQMATTFQQQSGGRLLVNVVTG
MAV_4628|M.avium_104 AMLVESTETLKF-LVAFRPGLLS-PTLAAQMAGTFQRHSQGRLLLNVVTG
MLBr_00269|M.leprae_Br4923 TAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLYPNRVFLGVGTG
: : * : : .: : *:: .: :: .*: :.: .
Mb0965c|M.bovis_AF2122/97 PWPEDYEL--MGVPFAK--RGKRIDECIEIVRGLTTG---DYFEFHGEFY
Rv0940c|M.tuberculosis_H37Rv PWPEDYEL--MGVPFAK--RGKRIDECIEIVRGLTTG---DYFEFHGEFY
MSMEG_3850|M.smegmatis_MC2_155 GDNVEQRR--FGDWLDHDERYARTGEFLHIVNRLWRQSGDESLDYEGTYY
MAB_2219|M.abscessus_ATCC_1997 GDDAEQRR--FGDWLTHDERYERTGEFLQIVRDIWRGS---PVDFSGKHY
Mflv_5136|M.gilvum_PYR-GCK GEAHEQRS--FGDHLDKDGRYARADEFLDVVRRLWDG---QTVSLDGEHI
Mvan_1200|M.vanbaalenii_PYR-1 GEAHEQRS--FGDYLDKEGRYARADEFLDVVRRLWDG---QTVTLDGEHI
TH_3352|M.thermoresistible__bu GESHEQRA--FGDHLDKDERYRRADEFLEVVRRLWAG---ETVTLHGRHI
MMAR_4200|M.marinum_M GEAHEQRA--YGDFLDKQQRYRRTGEFLHVVRQLWASG--QPVTFEGEHI
MUL_4507|M.ulcerans_Agy99 GEAHEQRA--YGDFLDKQQRYRRTGEFLHVVRQLWASG--QPVTFEGEHI
MAV_4628|M.avium_104 GEPHEQRA--YGDFLDKEARYARTAEFLHVVRQLWTSP--QPVTFAGEHI
MLBr_00269|M.leprae_Br4923 EALNEVATGYQGAWPEFKERFARLRESVRLMRELWRG---DRVDFDGDYY
: * * * * : ::. : . * .
Mb0965c|M.bovis_AF2122/97 DIPKTKMTPAPTQPIPILVGGHADAALRRAAR-ADGWMHG-GGDPDELDR
Rv0940c|M.tuberculosis_H37Rv DIPKTKMTPAPTQPIPILVGGHADAALRRAAR-ADGWMHG-GGDPDELDR
MSMEG_3850|M.smegmatis_MC2_155 NVADARVSAPPDPLPQIYFGGSSPAAMPIAAEHVDVYLTW-GEPPQDAAA
MAB_2219|M.abscessus_ATCC_1997 TVTDARVSEPPSPLPELYFGGSSPAALPIAADHVDVYLTW-GEPPAAAAA
Mflv_5136|M.gilvum_PYR-GCK RVENASLPTVPAPVPPLYFGGSSAAAGPVAARHADVYLTW-GEPPAAVAE
Mvan_1200|M.vanbaalenii_PYR-1 RVEGASLATLPDPAPPLYFGGSSAAAGPVAARHADVYLTW-GEPPAAVAD
TH_3352|M.thermoresistible__bu RVEDAALPTLPDPVPPLYFGGSSTAAGPVAARHADVYLTW-GEPPDAVRE
MMAR_4200|M.marinum_M HVHQAQLGRLPDPPPPVFFGGSSESAGAVAARYADTYLTW-GEPLSAVGK
MUL_4507|M.ulcerans_Agy99 HVHQAQLGRLPDPPPPVFFGGSSESAGAVAARYADTYLTW-GEPLSAVGK
MAV_4628|M.avium_104 RVEGAQLNNPPDPIPAVFFGGSSASAGPVAAKHSDVYLTW-GEPLTAVAK
MLBr_00269|M.leprae_Br4923 QLKGASIYDVPEGGVPIYIAAGGPEVAKYAGRAGEGFVCTSGKGEELYTE
: : : * : ... . . *. : :: *
Mb0965c|M.bovis_AF2122/97 LIARVKRLREEAGKTSPFEIHVISLDGFTVDG--------VKRLEDKGVT
Rv0940c|M.tuberculosis_H37Rv LIARVKRLREEAGKTSPFEIHVISLDGFTVDG--------VKRLEDKGVT
MSMEG_3850|M.smegmatis_MC2_155 KIARVRALAEERGRTVRFGIRLHTISRDTSAAAWAVAHDMVAGLDPEAIA
MAB_2219|M.abscessus_ATCC_1997 KIEAVRALAKERGRTLRFGIRLHTISRDTSEAAWAVANSLVGELTPDQIA
Mflv_5136|M.gilvum_PYR-GCK KVEWIRRAAAGQGRQLRFGIRLHVITRDTAGAAWAEADRLVGALDDETVR
Mvan_1200|M.vanbaalenii_PYR-1 KVDWIRRLAAKQGRQVRFGIRLHVITRDAADEAWSQADKLVSALDDETVR
TH_3352|M.thermoresistible__bu KIDWIRTLAAAEGRRVRFGIRLHTISRDTADEAWAQADKLIGALDEHTVR
MMAR_4200|M.marinum_M KIDWIRGLAADHGRALSYGLRIHVITRDTAEEAWRVADRLLAGIDPADIE
MUL_4507|M.ulcerans_Agy99 KIDWIRGLAADHGRALSYGLRIHVITRDTAEEAWRVADRLLAGIDPADIE
MAV_4628|M.avium_104 KLDWVRGLAVDAGRILQYGLRIHVISRDTSAAAWAEADRLLSAIDPADIE
MLBr_00269|M.leprae_Br4923 KLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQALSNIRFWAPLSLA
: . : : : :
Mb0965c|M.bovis_AF2122/97 DVIVGFRVPYTMG-------------------------------------
Rv0940c|M.tuberculosis_H37Rv DVIVGFRVPYTMG-------------------------------------
MSMEG_3850|M.smegmatis_MC2_155 KATALHSKSESEGQRRMTALHGGRTDK--------LEIYPNLWAGVGLVR
MAB_2219|M.abscessus_ATCC_1997 KATALHSKSESEGQRRMTALHGGRLDK--------LEIYPNLWAGVGLVR
Mflv_5136|M.gilvum_PYR-GCK NAQEGLGRSQSEGQRRMSALHQAHRANGSWHDARTLEVAPNLWTGVGLVR
Mvan_1200|M.vanbaalenii_PYR-1 SAQAGLGRSQSEGQRRMLALHEAHRADGSWHDARSLEIAPNLWAGVGLVR
TH_3352|M.thermoresistible__bu AAQAGLRRSESEGQRRMLALHQANRADGSWRSARSLEVAPNLWAGVGLVR
MMAR_4200|M.marinum_M RMQANLARSESEGQRRMAELHGGALDQ--------LEIAPNLWAGVGLVR
MUL_4507|M.ulcerans_Agy99 RMQANLARSESEGQRRMAELHGGVLDQ--------LEIAPNLWAGVGLVR
MAV_4628|M.avium_104 RVQASLARSESEGQRRMRELHGGDSGK--------LLVGPNLWAGVGLVR
MLBr_00269|M.leprae_Br4923 AEQKHSIDDPIEMEKVADALPIEQVAK-----------------------
Mb0965c|M.bovis_AF2122/97 --PDTEPLQTKIRNLEMFAENVIAKV------------------------
Rv0940c|M.tuberculosis_H37Rv --PDTEPLQTKIRNLEMFAENVIAKV------------------------
MSMEG_3850|M.smegmatis_MC2_155 GGAGTALVGSHEEVANLIYEYHSLGFDEFILSG--YPHLEESYWFAEGVL
MAB_2219|M.abscessus_ATCC_1997 GGAGTALVGSHEEVANLISEYHALGFDEFILSG--YPHLEEAYWFAEGVL
Mflv_5136|M.gilvum_PYR-GCK GGAGTALVGSHSEVADRIAEYAEVGIDEFIFSG--YPHLEELYWLGEGVV
Mvan_1200|M.vanbaalenii_PYR-1 GGAGTALVGSHTEVADRIAEYAEAGIDEFVFSG--YPHLEELFWFGEGVV
TH_3352|M.thermoresistible__bu GGAGTALVGSHAEVADRIAEYAAAGIEEFIFSG--YPHLEELFWFGEGVV
MMAR_4200|M.marinum_M GGAGTALVGSHQEVAERIIEYARLGISHFILSG--YPHLEEAYWFGEGVL
MUL_4507|M.ulcerans_Agy99 GGAGTALVGSHQEVAERIIEYARLGISHFILSG--YPHLEEAYWFGEGVL
MAV_4628|M.avium_104 GGAGTALVGSHAEVAERLAEYAKLGITHFILSG--YPHLEEAYWFGEGVL
MLBr_00269|M.leprae_Br4923 ---RWIVVSDPDEAVARVGQYVTWGLNHLVFHAPGHNQRRFLELFEKDLA
: . . : .
Mb0965c|M.bovis_AF2122/97 ---------------------------------
Rv0940c|M.tuberculosis_H37Rv ---------------------------------
MSMEG_3850|M.smegmatis_MC2_155 PILRRKGVAA-----------------------
MAB_2219|M.abscessus_ATCC_1997 PLLKKRGALAA----------------------
Mflv_5136|M.gilvum_PYR-GCK PLLRERGLFE-AGPKQAASASIPFVGGTGRGRI
Mvan_1200|M.vanbaalenii_PYR-1 PILRDRGLFT-ADVKGAAASSIPFVGAAR----
TH_3352|M.thermoresistible__bu PILRSRNLFDGAGDRSPVPAAIPFVGAAR----
MMAR_4200|M.marinum_M PILERKRLWHRPHGSSPHSAALPVAHSSVN---
MUL_4507|M.ulcerans_Agy99 PILERKRLWHRPHGSSPHSAALPVAHSSVN---
MAV_4628|M.avium_104 PLLERMGLWRHPNRRSRPAATTPFAVASAH---
MLBr_00269|M.leprae_Br4923 PRLRRLG--------------------------