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SLAFHWFLPTYGDSRNLVAGGHGTPMSGDRPATLRYLHQICSAAEDNGFEAVLTPTGLWCEDAWLTTAML VESTETLKFLVAFRPGLLSPTLAAQMAGTFQRHSQGRLLLNVVTGGEPHEQRAYGDFLDKEARYARTAEF LHVVRQLWTSPQPVTFAGEHIRVEGAQLNNPPDPIPAVFFGGSSASAGPVAAKHSDVYLTWGEPLTAVAK KLDWVRGLAVDAGRILQYGLRIHVISRDTSAAAWAEADRLLSAIDPADIERVQASLARSESEGQRRMREL HGGDSGKLLVGPNLWAGVGLVRGGAGTALVGSHAEVAERLAEYAKLGITHFILSGYPHLEEAYWFGEGVL PLLERMGLWRHPNRRSRPAATTPFAVASAH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4628 | - | - | 100% (381) | alkanesulfonate monoxygenase family protein |
| M. avium 104 | MAV_3426 | - | 4e-50 | 36.59% (369) | alkanesulfonate monooxygenase |
| M. avium 104 | MAV_0986 | - | 2e-10 | 25.86% (290) | hypothetical protein MAV_0986 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | 2e-12 | 26.42% (299) | hypothetical protein Mb0815c |
| M. gilvum PYR-GCK | Mflv_5136 | - | 1e-133 | 60.52% (385) | alkanesulfonate monooxygenase |
| M. tuberculosis H37Rv | Rv0791c | - | 2e-12 | 26.42% (299) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00348 | - | 1e-08 | 30.89% (123) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_2219 | - | 1e-122 | 59.67% (362) | putative alkanesulfonate monooxygenase |
| M. marinum M | MMAR_4200 | fgd2 | 1e-171 | 76.38% (381) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. smegmatis MC2 155 | MSMEG_2651 | - | 1e-131 | 61.75% (366) | alkanesulfonate monooxygenase family protein |
| M. thermoresistible (build 8) | TH_3352 | - | 1e-131 | 59.49% (390) | PUTATIVE Alkanesulfonate monooxygenase |
| M. ulcerans Agy99 | MUL_4507 | fgd2 | 1e-170 | 75.85% (381) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. vanbaalenii PYR-1 | Mvan_1200 | - | 1e-133 | 59.90% (389) | alkanesulfonate monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4200|M.marinum_M ----------------------------MALSFHWFLPTYGDSRGLVAGG
MUL_4507|M.ulcerans_Agy99 ----------------------------MALLFHWFLPTYGDSRGLVAGG
MAV_4628|M.avium_104 ----------------------------MSLAFHWFLPTYGDSRNLVAGG
MSMEG_2651|M.smegmatis_MC2_155 --------------------------------MHWFLPTYGDSRLIVGGG
TH_3352|M.thermoresistible__bu ----------------------------VTIKLHWFLPTYGDSRLIVGGG
Mflv_5136|M.gilvum_PYR-GCK --------------------------MTHAIKLHWFLPTYGDSRHIVGGG
Mvan_1200|M.vanbaalenii_PYR-1 MCTVAVLQIPLTQTADLPTPSGHHLVVTSAIKLHWFLPTYGDSRLIVGGG
MAB_2219|M.abscessus_ATCC_1997 ----------------------------MAAKFFWFLPTNGDSRSIVGAS
Mb0815c|M.bovis_AF2122/97 ---------------MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTA
Rv0791c|M.tuberculosis_H37Rv ---------------MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTA
MLBr_00348|M.leprae_Br4923 -----------------------------------MVERANAMKLGLQLG
: .
MMAR_4200|M.marinum_M HG------------LPMS---GNRPATLRYLNQIAAAAESNGFEAVLTPA
MUL_4507|M.ulcerans_Agy99 HG------------LPMS---GNRPATLRYLNQIAAAAESNGFEAVLTPA
MAV_4628|M.avium_104 HG------------TPMS---GDRPATLRYLHQICSAAEDNGFEAVLTPT
MSMEG_2651|M.smegmatis_MC2_155 HG------------TPLGAAGGDREASIDYLASIVRAAERFGFTGALIPT
TH_3352|M.thermoresistible__bu HG------------TPAGAAGGDRDASIDYLASIVRAAETFGFTGALIPT
Mflv_5136|M.gilvum_PYR-GCK HG------------TPAGSAHSDRDASIDYLASIVRAAETFGFTGALIPT
Mvan_1200|M.vanbaalenii_PYR-1 HG------------TPAGAARGDRDASIDYLASIVRAAETFGFTGALIPT
MAB_2219|M.abscessus_ATCC_1997 HAS-----------THHTVPEGYREPSLRYLGEVARAADRLGFEGVLTPT
Mb0815c|M.bovis_AF2122/97 EEYGFDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSR
Rv0791c|M.tuberculosis_H37Rv EEYGFDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSR
MLBr_00348|M.leprae_Br4923 ---------------------YWAAQPPGNAAELVAAAEGAGFDAVFTG-
.:: *
MMAR_4200|M.marinum_M GLWCEDAWLTTAMLVGTTETLKFLVALRP-GLVSPTLAAQMATTFQQQSG
MUL_4507|M.ulcerans_Agy99 GLWCEDAWLTTAMLVGTTKTLKFLVALRP-GLVSPTLAAQMATTFQQQSG
MAV_4628|M.avium_104 GLWCEDAWLTTAMLVESTETLKFLVAFRP-GLLSPTLAAQMAGTFQRHSQ
MSMEG_2651|M.smegmatis_MC2_155 GAWCEDAFVTAALLARETTSLAFLVAFRP-GLVSPTLSAQMAATFAKHAP
TH_3352|M.thermoresistible__bu GAWCEDAFITAALLARETTSLGFLVAFRP-GLVSPTLSAQMAATFARHAP
Mflv_5136|M.gilvum_PYR-GCK GAWCEDAFITAALLARETSTLGFLVAFRP-GLVSPTLSAQMAATFARHAP
Mvan_1200|M.vanbaalenii_PYR-1 GAWCEDAFITAALLARETTSLAFLVAFRP-GLVSPTLSAQMAATFARHAP
MAB_2219|M.abscessus_ATCC_1997 GTWCEDAWLTAAGLLDQTERLKFLVAFRP-GLVPPTLAAQQAATLQRFSN
Mb0815c|M.bovis_AF2122/97 SLPLLECWTALAALSRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQ
Rv0791c|M.tuberculosis_H37Rv SLPLLECWTALAALSRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQ
MLBr_00348|M.leprae_Br4923 EAWGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSG
:.: . * * : : .:. . *: * * *: :
MMAR_4200|M.marinum_M GRLLLNVVTGGEAHEQRAYGDFLDKQ-QRYRRTGEFLHVVRQLWASGQPV
MUL_4507|M.ulcerans_Agy99 GRLLVNVVTGGEAHEQRAYGDFLDKQ-QRYRRTGEFLHVVRQLWASGQPV
MAV_4628|M.avium_104 GRLLLNVVTGGEPHEQRAYGDFLDKE-ARYARTAEFLHVVRQLWTSPQPV
MSMEG_2651|M.smegmatis_MC2_155 GRILLNVVVGGEAHEQRAFGDHLDKE-ERYARCDEFLDVVRRLWAG-ETV
TH_3352|M.thermoresistible__bu GRILLNVVVGGESHEQRAFGDHLDKD-ERYRRADEFLEVVRRLWAG-ETV
Mflv_5136|M.gilvum_PYR-GCK GRLLLNVVVGGEAHEQRSFGDHLDKD-GRYARADEFLDVVRRLWDG-QTV
Mvan_1200|M.vanbaalenii_PYR-1 GRILLNVVVGGEAHEQRSFGDYLDKE-GRYARADEFLDVVRRLWDG-QTV
MAB_2219|M.abscessus_ATCC_1997 GRLLLNVVSGGDDAEQRRFGDWLTHD-ERYERTGEFLQIVRDIWRG-SPV
Mb0815c|M.bovis_AF2122/97 GRLDLGLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTE-PNP
Rv0791c|M.tuberculosis_H37Rv GRLDLGLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTE-PNP
MLBr_00348|M.leprae_Br4923 GRHILGLGVSGPQVVEGWYGQPFPKP---LSRTREYIDIVRQVWAREAPV
** :.: . . :* : * :.::: :*
MMAR_4200|M.marinum_M TFEGEHIHVHQAQLGRLPD------------PPPPVFFGGSSESAGAVAA
MUL_4507|M.ulcerans_Agy99 TFEGEHIHVHQAQLGRLPD------------PPPPVFFGGSSESAGAVAA
MAV_4628|M.avium_104 TFAGEHIRVEGAQLNNPPD------------PIPAVFFGGSSASAGPVAA
MSMEG_2651|M.smegmatis_MC2_155 THRGKYIDVEEASLAAPPN------------PVPPLYFGGSSAAAGPVAA
TH_3352|M.thermoresistible__bu TLHGRHIRVEDAALPTLPD------------PVPPLYFGGSSTAAGPVAA
Mflv_5136|M.gilvum_PYR-GCK SLDGEHIRVENASLPTVPA------------PVPPLYFGGSSAAAGPVAA
Mvan_1200|M.vanbaalenii_PYR-1 TLDGEHIRVEGASLATLPD------------PAPPLYFGGSSAAAGPVAA
MAB_2219|M.abscessus_ATCC_1997 DFSGKHYTVTDARVSEPPS------------PLPELYFGGSSPAALPIAA
Mb0815c|M.bovis_AF2122/97 TYAGRFYTLDGATCDPPPVQ----------RPHPPLWIGGEGDRVQRIAA
Rv0791c|M.tuberculosis_H37Rv TYAGRFYTLDGATCDPPPVQ----------RPHPPLWIGGEGDRVQRIAA
MLBr_00348|M.leprae_Br4923 VSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAA
*.. : : . : :*... :**
MMAR_4200|M.marinum_M RYADTYLTWGEPLSAVGKKIDWIRGLAADHGRALSYGLRIHVITRDTAEE
MUL_4507|M.ulcerans_Agy99 RYADTYLTWGEPLSAVGKKIDWIRGLAADHGRALSYGLRIHVITRDTAEE
MAV_4628|M.avium_104 KHSDVYLTWGEPLTAVAKKLDWVRGLAVDAGRILQYGLRIHVISRDTSAA
MSMEG_2651|M.smegmatis_MC2_155 RHSDVYLTWGEPPEAVREKIEWIRKLGEEQGRKLRFGIRLHTISRDTSEE
TH_3352|M.thermoresistible__bu RHADVYLTWGEPPDAVREKIDWIRTLAAAEGRRVRFGIRLHTISRDTADE
Mflv_5136|M.gilvum_PYR-GCK RHADVYLTWGEPPAAVAEKVEWIRRAAAGQGRQLRFGIRLHVITRDTAGA
Mvan_1200|M.vanbaalenii_PYR-1 RHADVYLTWGEPPAAVADKVDWIRRLAAKQGRQVRFGIRLHVITRDAADE
MAB_2219|M.abscessus_ATCC_1997 DHVDVYLTWGEPPAAAAAKIEAVRALAKERGRTLRFGIRLHTISRDTSEA
Mb0815c|M.bovis_AF2122/97 KHAQGLNVRWWSPQQVTQRRGFLTQASEAAGR-------------DPDTL
Rv0791c|M.tuberculosis_H37Rv KHAQGLNVRWWSPQQVTQRRGFLTQASEAAGR-------------DPDTL
MLBr_00348|M.leprae_Br4923 EICDGWLPIFFSPRMADMYNEWLDEGFARTGAR-----------RSREDF
: . . : * .
MMAR_4200|M.marinum_M AWRVADRLLAGIDPADIERMQANLARSESEGQRRMAELHGG--------A
MUL_4507|M.ulcerans_Agy99 AWRVADRLLAGIDPADIERMQANLARSESEGQRRMAELHGG--------V
MAV_4628|M.avium_104 AWAEADRLLSAIDPADIERVQASLARSESEGQRRMRELHGG--------D
MSMEG_2651|M.smegmatis_MC2_155 AWAQADKLVAALDEETVRKAQEGLARSQSEGQRRMLALHEANRLNGTWSD
TH_3352|M.thermoresistible__bu AWAQADKLIGALDEHTVRAAQAGLRRSESEGQRRMLALHQANRADGSWRS
Mflv_5136|M.gilvum_PYR-GCK AWAEADRLVGALDDETVRNAQEGLGRSQSEGQRRMSALHQAHRANGSWHD
Mvan_1200|M.vanbaalenii_PYR-1 AWSQADKLVSALDDETVRSAQAGLGRSQSEGQRRMLALHEAHRADGSWHD
MAB_2219|M.abscessus_ATCC_1997 AWAVANSLVGELTPDQIAKATALHSKSESEGQRRMTALHGG--------R
Mb0815c|M.bovis_AF2122/97 RLSVTLLLAPTQSGEEEVRIREEFASIPEPG-------------------
Rv0791c|M.tuberculosis_H37Rv RLSVTLLLAPTQSGEEEVRIREEFASIPEPG-------------------
MLBr_00348|M.leprae_Br4923 EICASAQIVVTEDRAAAFAGIKPFLALYMGGMG---------------AE
: : *
MMAR_4200|M.marinum_M LDQLEIAPNLWAGVGLVRGGAGTALVGSHQEVAERIIEYARLGISHFILS
MUL_4507|M.ulcerans_Agy99 LDQLEIAPNLWAGVGLVRGGAGTALVGSHQEVAERIIEYARLGISHFILS
MAV_4628|M.avium_104 SGKLLVGPNLWAGVGLVRGGAGTALVGSHAEVAERLAEYAKLGITHFILS
MSMEG_2651|M.smegmatis_MC2_155 ARSLEIAPNLWAGVGLVRGGAGTALVGSHTEVADRIAEYAEIGIDEFIFS
TH_3352|M.thermoresistible__bu ARSLEVAPNLWAGVGLVRGGAGTALVGSHAEVADRIAEYAAAGIEEFIFS
Mflv_5136|M.gilvum_PYR-GCK ARTLEVAPNLWTGVGLVRGGAGTALVGSHSEVADRIAEYAEVGIDEFIFS
Mvan_1200|M.vanbaalenii_PYR-1 ARSLEIAPNLWAGVGLVRGGAGTALVGSHTEVADRIAEYAEAGIDEFVFS
MAB_2219|M.abscessus_ATCC_1997 LDKLEIYPNLWAGVGLVRGGAGTALVGSHEEVANLISEYHALGFDEFILS
Mb0815c|M.bovis_AF2122/97 -----------------------LIVGTPDRCVERIREYQDRGVGHFLFT
Rv0791c|M.tuberculosis_H37Rv -----------------------LIVGTPDRCVERIREYQDRGVGHFLFT
MLBr_00348|M.leprae_Br4923 GTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPN-ELVDSTMIVG
: .. . : ::.
MMAR_4200|M.marinum_M G--YPHLEEAYWFGEGVLPILERKRLWHRPHGSSPHSAALPVAHSSVN--
MUL_4507|M.ulcerans_Agy99 G--YPHLEEAYWFGEGVLPILERKRLWHRPHGSSPHSAALPVAHSSVN--
MAV_4628|M.avium_104 G--YPHLEEAYWFGEGVLPLLERMGLWRHPNRRSRPAATTPFAVASAH--
MSMEG_2651|M.smegmatis_MC2_155 G--YPHLEELFWFGEGVVPILRKRGLFD-AGALDCAPASIPFVGAAR---
TH_3352|M.thermoresistible__bu G--YPHLEELFWFGEGVVPILRSRNLFDGAGDRSPVPAAIPFVGAAR---
Mflv_5136|M.gilvum_PYR-GCK G--YPHLEELYWLGEGVVPLLRERGLFE-AGPKQAASASIPFVGGTGRGR
Mvan_1200|M.vanbaalenii_PYR-1 G--YPHLEELFWFGEGVVPILRDRGLFT-ADVKGAAASSIPFVGAAR---
MAB_2219|M.abscessus_ATCC_1997 G--YPHLEEAYWFAEGVLPLLKKRGALAA---------------------
Mb0815c|M.bovis_AF2122/97 IPHVVKSDYLHIIGSDIIPRVKTEVTIP----------------------
Rv0791c|M.tuberculosis_H37Rv IPHVVKSDYLHIIGSDIIPRVKTEVTIP----------------------
MLBr_00348|M.leprae_Br4923 DVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF-------------
: . .: :
MMAR_4200|M.marinum_M -
MUL_4507|M.ulcerans_Agy99 -
MAV_4628|M.avium_104 -
MSMEG_2651|M.smegmatis_MC2_155 -
TH_3352|M.thermoresistible__bu -
Mflv_5136|M.gilvum_PYR-GCK I
Mvan_1200|M.vanbaalenii_PYR-1 -
MAB_2219|M.abscessus_ATCC_1997 -
Mb0815c|M.bovis_AF2122/97 -
Rv0791c|M.tuberculosis_H37Rv -
MLBr_00348|M.leprae_Br4923 -