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AVDRLLPTDEARELVDLARQIADKALDPIVDQHEKDETYPDGVFATLGEAGLLSLPYPEEWGGGGQPYEV YLQVLEELAARWAAVAVAVSVHSLSCHPLMSFGTDEQRQRWLPEMLGGSTIGAYSLSEPQAGSDAAALTC KAVAADGGYRINGAKAWITHGGIADFYNLFARTGEGSQGISCFLVPRDTEGLTFGKPEEKMGLHAVPTTA AHYENAFVEADRRIGAEGQGLQIAFSALDSGRLGIAAVAVGLAQAALDAAVDYSQERTTFGRKIIDHQGL AFLLADMAAAVDAARATYLDAARRRDAGLPYSRHASVAKLTATDAAMKVTTDAVQVFGGAGYTRDYRVER YMREAKITQIFEGTNQIQRLVISRHLARD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_1476 | - | - | 100% (380) | acyl-CoA dehydrogenase domain-containing protein |
M. vanbaalenii PYR-1 | Mvan_1719 | - | 2e-76 | 42.90% (373) | acyl-CoA dehydrogenase domain-containing protein |
M. vanbaalenii PYR-1 | Mvan_4089 | - | 8e-68 | 38.99% (377) | acyl-CoA dehydrogenase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3302c | fadE25 | 7e-77 | 42.63% (373) | acyl-CoA dehydrogenase FADE25 |
M. gilvum PYR-GCK | Mflv_4943 | - | 0.0 | 92.88% (379) | acyl-CoA dehydrogenase domain-containing protein |
M. tuberculosis H37Rv | Rv3274c | fadE25 | 7e-77 | 42.63% (373) | acyl-CoA dehydrogenase FADE25 |
M. leprae Br4923 | MLBr_00737 | fadE25 | 1e-75 | 42.09% (373) | putative acyl-CoA dehydrogenase |
M. abscessus ATCC 19977 | MAB_3618c | - | 2e-73 | 42.05% (371) | acyl-CoA dehydrogenase FadE |
M. marinum M | MMAR_1262 | fadE25 | 1e-76 | 42.63% (373) | acyl-CoA dehydrogenase FadE25 |
M. avium 104 | MAV_2668 | - | 0.0 | 88.33% (377) | acyl-CoA dehydrogenase |
M. smegmatis MC2 155 | MSMEG_0108 | - | 1e-177 | 81.43% (377) | acyl-CoA dehydrogenase |
M. thermoresistible (build 8) | TH_4603 | - | 1e-179 | 82.06% (379) | PUTATIVE acyl-CoA dehydrogenase domain protein |
M. ulcerans Agy99 | MUL_2626 | fadE25 | 3e-77 | 43.16% (373) | acyl-CoA dehydrogenase FadE25 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_1262|M.marinum_M MAGWAGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE MUL_2626|M.ulcerans_Agy99 MAGWAGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE Mb3302c|M.bovis_AF2122/97 MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE Rv3274c|M.tuberculosis_H37Rv MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE MAB_3618c|M.abscessus_ATCC_199 ---MAGNPSFDLFKLGEEHDELRAAIRGLAEKEIAPHAKDVDEKARFPQE Mvan_1476|M.vanbaalenii_PYR-1 -------MAVDRLLPTDEARELVDLARQIADKALDPIVDQHEKDETYPDG Mflv_4943|M.gilvum_PYR-GCK -------MPVDRLLPTDDARDLVELARQIADKVLDPIVDRHEKDETYPEG MAV_2668|M.avium_104 -------MTVDRLLPTPEARELVRLAADVADKVLDPIVDEHEKNETYPEG MSMEG_0108|M.smegmatis_MC2_155 -------MSVDRLLPSEEARDLIALTREVADKVLDPIVDEHERNETYPEG TH_4603|M.thermoresistible__bu -------MAVDRLLPSQEAAELIELTREIADKVLDPIVDRHEKDETYPEG .* : : :: :*:* : * . :. :*: MMAR_1262|M.marinum_M ALDALNASGFNAVHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN MUL_2626|M.ulcerans_Agy99 ALDALNASGFNALHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN Mb3302c|M.bovis_AF2122/97 ALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVN Rv3274c|M.tuberculosis_H37Rv ALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVN MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN MAB_3618c|M.abscessus_ATCC_199 ALDALVASGFNAVHVPEEYDGQGADSVAACIVIEEVARVCASSSLIPAVN Mvan_1476|M.vanbaalenii_PYR-1 VFATLGEAGLLSLPYPEEWGGGGQPYEVYLQVLEELAARWAAVAVAVSVH Mflv_4943|M.gilvum_PYR-GCK VFATLGEAGLLSLPYPEEWGGGGQPYEVYLQVLEELAARWAAVAVAVSVH MAV_2668|M.avium_104 VFATLGETGLLTLPHPEQWGGGGQPYEVYLQVLEELAARWAAVAVAVSVH MSMEG_0108|M.smegmatis_MC2_155 VFAQLGAAGLLSLPQPEQWGGGGQPYEVYLQVLEEIAARWAAVAVAVSVH TH_4603|M.thermoresistible__bu VFEQLGAAGLLSLPQPEEWGGGGQPYEVYLQVLEEIAARWASVAVAVSVH .: * :*: :: **::.* * . *:**:* *: :: :*: MMAR_1262|M.marinum_M KLGTMGLILRGSDDLKKQVLPSLADGAAMASYALSEREAGSDAGAMRTRA MUL_2626|M.ulcerans_Agy99 KLGTMGLILRGSDELKKQVLPSLADGAAMASYALSEREAGSDAGAMRTRA Mb3302c|M.bovis_AF2122/97 KLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRA Rv3274c|M.tuberculosis_H37Rv KLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRA MLBr_00737|M.leprae_Br4923 KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA MAB_3618c|M.abscessus_ATCC_199 KLGTMGLILNGSDELKKQVLPAIASGEAMASYALSEREAGSDAASMRTRA Mvan_1476|M.vanbaalenii_PYR-1 SLSCHPLMSFGTDEQRQRWLPEMLGGSTIGAYSLSEPQAGSDAAALTCKA Mflv_4943|M.gilvum_PYR-GCK SLSCHPLMSFGSDEQRQRWLPDMLGGSTIGAYSLSEPQAGSDAAALTCRA MAV_2668|M.avium_104 VLSCHPLIAFGTDEQQQEWLPTMLGGHTIGAYSLSEPQAGSDAAALTCKA MSMEG_0108|M.smegmatis_MC2_155 SLSSHPLLAFGTDEQKQRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAA TH_4603|M.thermoresistible__bu SLSSHPLLVFGTEEQKKRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAA *. *: *::: ::. ** : :.:*:*** :*****.:: * MMAR_1262|M.marinum_M KADGDDWILNGTKCWITNGGKSSWYTVMAVTDPEKGANGISAFMVHKDDE MUL_2626|M.ulcerans_Agy99 KADGDDWILNGTKCWITNGGKSSWYTVMAVTDPENGANGISAFVVHKDDE Mb3302c|M.bovis_AF2122/97 KADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKDDE Rv3274c|M.tuberculosis_H37Rv KADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKDDE MLBr_00737|M.leprae_Br4923 KADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKDDE MAB_3618c|M.abscessus_ATCC_199 KADGDDWIINGSKCWITNGGKSSWYTVMAVTDPEKKANGISAFMVHKDDE Mvan_1476|M.vanbaalenii_PYR-1 VAADGGYRINGAKAWITHGGIADFYNLFARTG--EGSQGISCFLVPRDTE Mflv_4943|M.gilvum_PYR-GCK TAVDGGYRITGSKAWITHGGIADFYNLFARTG--EGSQGISCFLVPRDTE MAV_2668|M.avium_104 TATDGGYRVNGAKAWITHGGIADFYSLFARTG--EGGQGISCFLVDKDTE MSMEG_0108|M.smegmatis_MC2_155 RRDGDGFVLNGSKAWITHGGRADFYTLFARTG--EGSKGVSCFLVPGDLP TH_4603|M.thermoresistible__bu TPTDGGYVINGSKSWITHGGKADFYTLFARTG--EGSRGVSCFLVPADQP .. : :.* *.***:** : :*.::* *. . ..*:*.*:* * MMAR_1262|M.marinum_M GFVVGPKERKLGIKGSPTTELYFENCRVPGDRMIGEPGTGFKTALATLDH MUL_2626|M.ulcerans_Agy99 GFVVGPKERKLGIKGSPTTELYFENCRVPGDRMIGEPGTGFKTALATLDH Mb3302c|M.bovis_AF2122/97 GFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDH Rv3274c|M.tuberculosis_H37Rv GFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDH MLBr_00737|M.leprae_Br4923 GFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATLDH MAB_3618c|M.abscessus_ATCC_199 GFTVGPLEHKLGIKGSPTAELYFENCRIPGDRIIGEPGTGFKTALQTLDH Mvan_1476|M.vanbaalenii_PYR-1 GLTFGKPEEKMGLHAVPTTAAHYENAFVEADRRIGAEGQGLQIAFSALDS Mflv_4943|M.gilvum_PYR-GCK GLTFGKPEEKMGLHAVPTTAAHYDDANLDSDRRIGTEGQGLQIAFSALDS MAV_2668|M.avium_104 GLTFGKPEEKMGLHAIPTTTAHYDNALVSAQRRIGAEGQGLQIAFSALDS MSMEG_0108|M.smegmatis_MC2_155 GLSFGKPEEKMGLHAVPTTSAFYDNARIDADRLIGTEGQGLSIAFSALDS TH_4603|M.thermoresistible__bu GLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAFSALDS *: .* *.*:*::. **: .::.. : .:* ** * *:. *: :** MMAR_1262|M.marinum_M TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGKSISDFQAVQFMLADMAMK MUL_2626|M.ulcerans_Agy99 TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGKSISDFQAVQFMLADMAMK Mb3302c|M.bovis_AF2122/97 TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMK Rv3274c|M.tuberculosis_H37Rv TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMK MLBr_00737|M.leprae_Br4923 TRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMK MAB_3618c|M.abscessus_ATCC_199 TRPTIGAQALGIAQGALDQAIAYTKDRKQFGKSISDFQGVQFMLADMAMK Mvan_1476|M.vanbaalenii_PYR-1 GRLGIAAVAVGLAQAALDAAVDYSQERTTFGRKIIDHQGLAFLLADMAAA Mflv_4943|M.gilvum_PYR-GCK GRLGIAAVAVGLAQAALDEAVAYSQERTTFGRKIIDHQGLAFLLADMAAA MAV_2668|M.avium_104 GRLGIAAVAVGLAQAALDEAVSYAQQRTTFGRKIIDHQGLAFLLADMAAA MSMEG_0108|M.smegmatis_MC2_155 GRLGIAAVAVGIAQAALDEAVRYAHERTTFGRKIIDHQGLGFLLADMAAA TH_4603|M.thermoresistible__bu GRLGIAAVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADMAAA * *.* * *:**.*** *: *:::*. **..* .*.: *:***** MMAR_1262|M.marinum_M VESARLMVYSAAARAERGESNLGFISAASKCLASDVAMEVTTDAVQLFGG MUL_2626|M.ulcerans_Agy99 VESARLMVYSAAARAERGESNLGFISAASKCLASDVAMEVTTDAVQLFGG Mb3302c|M.bovis_AF2122/97 VEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLFGG Rv3274c|M.tuberculosis_H37Rv VEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLFGG MLBr_00737|M.leprae_Br4923 VEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLFGG MAB_3618c|M.abscessus_ATCC_199 VEAARLMVYTAAARAERGEKNLGFISSASKCFASDVAMEVTTDAVQLFGG Mvan_1476|M.vanbaalenii_PYR-1 VDAARATYLDAARRRDAGLP-YSRHASVAKLTATDAAMKVTTDAVQVFGG Mflv_4943|M.gilvum_PYR-GCK VDSARATYLDAARRRDAGLP-YSRHASVAKLVATDAAMKVTTDAVQVLGG MAV_2668|M.avium_104 VDSARATYLDAARRRDAGLP-YSRNASVAKLIATDAAMKVTTDAVQVFGG MSMEG_0108|M.smegmatis_MC2_155 VVSARATYLDAARRRDAGLP-YSSQASVAKLVATDAAMKVTTDAVQVLGG TH_4603|M.thermoresistible__bu VATARATYLDAARRRDQGRP-YSQQASIAKLTATDAAMKVTTDAVQVFGG * :** ** * : * . :: :* *:* **:*******::** MMAR_1262|M.marinum_M AGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR- MUL_2626|M.ulcerans_Agy99 AGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR- Mb3302c|M.bovis_AF2122/97 AGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR- Rv3274c|M.tuberculosis_H37Rv AGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR- MLBr_00737|M.leprae_Br4923 AGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR- MAB_3618c|M.abscessus_ATCC_199 AGYTTDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLTS Mvan_1476|M.vanbaalenii_PYR-1 AGYTRDYRVERYMREAKITQIFEGTNQIQRLVISRHLARD Mflv_4943|M.gilvum_PYR-GCK AGYTRDYRVERYMREAKITQIFEGTNQIQRLVISRHLTRG MAV_2668|M.avium_104 YGYTRDYRVERYMREAKITQIFEGTNQIQRLVIGRSLVGS MSMEG_0108|M.smegmatis_MC2_155 VGYTRDFRVERYMREAKITQIFEGTNQIQRLVISRGLGT- TH_4603|M.thermoresistible__bu VGYTRDYRVERYMREAKIMQIFEGTNQIQRLVIARGLTR- *** *: *** **:*** **:********:*:.* *