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M. vanbaalenii PYR-1 Mvan_1476 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 1566972 - 1568114
length: 380

AVDRLLPTDEARELVDLARQIADKALDPIVDQHEKDETYPDGVFATLGEAGLLSLPYPEEWGGGGQPYEV
YLQVLEELAARWAAVAVAVSVHSLSCHPLMSFGTDEQRQRWLPEMLGGSTIGAYSLSEPQAGSDAAALTC
KAVAADGGYRINGAKAWITHGGIADFYNLFARTGEGSQGISCFLVPRDTEGLTFGKPEEKMGLHAVPTTA
AHYENAFVEADRRIGAEGQGLQIAFSALDSGRLGIAAVAVGLAQAALDAAVDYSQERTTFGRKIIDHQGL
AFLLADMAAAVDAARATYLDAARRRDAGLPYSRHASVAKLTATDAAMKVTTDAVQVFGGAGYTRDYRVER
YMREAKITQIFEGTNQIQRLVISRHLARD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_1476--100% (380)acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1Mvan_1719-2e-7642.90% (373) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1Mvan_4089-8e-6838.99% (377) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3302cfadE257e-7742.63% (373) acyl-CoA dehydrogenase FADE25
M. gilvum PYR-GCKMflv_4943-0.092.88% (379) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv3274cfadE257e-7742.63% (373) acyl-CoA dehydrogenase FADE25
M. leprae Br4923MLBr_00737fadE251e-7542.09% (373) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_3618c-2e-7342.05% (371) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_1262fadE251e-7642.63% (373) acyl-CoA dehydrogenase FadE25
M. avium 104MAV_2668-0.088.33% (377) acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_0108-1e-17781.43% (377) acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_4603-1e-17982.06% (379) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99MUL_2626fadE253e-7743.16% (373) acyl-CoA dehydrogenase FadE25

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1262|M.marinum_M               MAGWAGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE
MUL_2626|M.ulcerans_Agy99           MAGWAGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE
Mb3302c|M.bovis_AF2122/97           MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE
Rv3274c|M.tuberculosis_H37Rv        MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
MAB_3618c|M.abscessus_ATCC_199      ---MAGNPSFDLFKLGEEHDELRAAIRGLAEKEIAPHAKDVDEKARFPQE
Mvan_1476|M.vanbaalenii_PYR-1       -------MAVDRLLPTDEARELVDLARQIADKALDPIVDQHEKDETYPDG
Mflv_4943|M.gilvum_PYR-GCK          -------MPVDRLLPTDDARDLVELARQIADKVLDPIVDRHEKDETYPEG
MAV_2668|M.avium_104                -------MTVDRLLPTPEARELVRLAADVADKVLDPIVDEHEKNETYPEG
MSMEG_0108|M.smegmatis_MC2_155      -------MSVDRLLPSEEARDLIALTREVADKVLDPIVDEHERNETYPEG
TH_4603|M.thermoresistible__bu      -------MAVDRLLPSQEAAELIELTREIADKVLDPIVDRHEKDETYPEG
                                             .* :    :  ::      :*:* : * .   :.   :*: 

MMAR_1262|M.marinum_M               ALDALNASGFNAVHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
MUL_2626|M.ulcerans_Agy99           ALDALNASGFNALHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
Mb3302c|M.bovis_AF2122/97           ALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVN
Rv3274c|M.tuberculosis_H37Rv        ALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVN
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
MAB_3618c|M.abscessus_ATCC_199      ALDALVASGFNAVHVPEEYDGQGADSVAACIVIEEVARVCASSSLIPAVN
Mvan_1476|M.vanbaalenii_PYR-1       VFATLGEAGLLSLPYPEEWGGGGQPYEVYLQVLEELAARWAAVAVAVSVH
Mflv_4943|M.gilvum_PYR-GCK          VFATLGEAGLLSLPYPEEWGGGGQPYEVYLQVLEELAARWAAVAVAVSVH
MAV_2668|M.avium_104                VFATLGETGLLTLPHPEQWGGGGQPYEVYLQVLEELAARWAAVAVAVSVH
MSMEG_0108|M.smegmatis_MC2_155      VFAQLGAAGLLSLPQPEQWGGGGQPYEVYLQVLEEIAARWAAVAVAVSVH
TH_4603|M.thermoresistible__bu      VFEQLGAAGLLSLPQPEEWGGGGQPYEVYLQVLEEIAARWASVAVAVSVH
                                    .:  *  :*: ::  **::.* *    .   *:**:*   *: ::  :*:

MMAR_1262|M.marinum_M               KLGTMGLILRGSDDLKKQVLPSLADGAAMASYALSEREAGSDAGAMRTRA
MUL_2626|M.ulcerans_Agy99           KLGTMGLILRGSDELKKQVLPSLADGAAMASYALSEREAGSDAGAMRTRA
Mb3302c|M.bovis_AF2122/97           KLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRA
Rv3274c|M.tuberculosis_H37Rv        KLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRA
MLBr_00737|M.leprae_Br4923          KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
MAB_3618c|M.abscessus_ATCC_199      KLGTMGLILNGSDELKKQVLPAIASGEAMASYALSEREAGSDAASMRTRA
Mvan_1476|M.vanbaalenii_PYR-1       SLSCHPLMSFGTDEQRQRWLPEMLGGSTIGAYSLSEPQAGSDAAALTCKA
Mflv_4943|M.gilvum_PYR-GCK          SLSCHPLMSFGSDEQRQRWLPDMLGGSTIGAYSLSEPQAGSDAAALTCRA
MAV_2668|M.avium_104                VLSCHPLIAFGTDEQQQEWLPTMLGGHTIGAYSLSEPQAGSDAAALTCKA
MSMEG_0108|M.smegmatis_MC2_155      SLSSHPLLAFGTDEQKQRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAA
TH_4603|M.thermoresistible__bu      SLSSHPLLVFGTEEQKKRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAA
                                     *.   *:  *::: ::. ** :     :.:*:*** :*****.::   *

MMAR_1262|M.marinum_M               KADGDDWILNGTKCWITNGGKSSWYTVMAVTDPEKGANGISAFMVHKDDE
MUL_2626|M.ulcerans_Agy99           KADGDDWILNGTKCWITNGGKSSWYTVMAVTDPENGANGISAFVVHKDDE
Mb3302c|M.bovis_AF2122/97           KADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKDDE
Rv3274c|M.tuberculosis_H37Rv        KADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKDDE
MLBr_00737|M.leprae_Br4923          KADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKDDE
MAB_3618c|M.abscessus_ATCC_199      KADGDDWIINGSKCWITNGGKSSWYTVMAVTDPEKKANGISAFMVHKDDE
Mvan_1476|M.vanbaalenii_PYR-1       VAADGGYRINGAKAWITHGGIADFYNLFARTG--EGSQGISCFLVPRDTE
Mflv_4943|M.gilvum_PYR-GCK          TAVDGGYRITGSKAWITHGGIADFYNLFARTG--EGSQGISCFLVPRDTE
MAV_2668|M.avium_104                TATDGGYRVNGAKAWITHGGIADFYSLFARTG--EGGQGISCFLVDKDTE
MSMEG_0108|M.smegmatis_MC2_155      RRDGDGFVLNGSKAWITHGGRADFYTLFARTG--EGSKGVSCFLVPGDLP
TH_4603|M.thermoresistible__bu      TPTDGGYVINGSKSWITHGGKADFYTLFARTG--EGSRGVSCFLVPADQP
                                       .. : :.* *.***:** : :*.::* *.  . ..*:*.*:*  *  

MMAR_1262|M.marinum_M               GFVVGPKERKLGIKGSPTTELYFENCRVPGDRMIGEPGTGFKTALATLDH
MUL_2626|M.ulcerans_Agy99           GFVVGPKERKLGIKGSPTTELYFENCRVPGDRMIGEPGTGFKTALATLDH
Mb3302c|M.bovis_AF2122/97           GFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDH
Rv3274c|M.tuberculosis_H37Rv        GFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDH
MLBr_00737|M.leprae_Br4923          GFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATLDH
MAB_3618c|M.abscessus_ATCC_199      GFTVGPLEHKLGIKGSPTAELYFENCRIPGDRIIGEPGTGFKTALQTLDH
Mvan_1476|M.vanbaalenii_PYR-1       GLTFGKPEEKMGLHAVPTTAAHYENAFVEADRRIGAEGQGLQIAFSALDS
Mflv_4943|M.gilvum_PYR-GCK          GLTFGKPEEKMGLHAVPTTAAHYDDANLDSDRRIGTEGQGLQIAFSALDS
MAV_2668|M.avium_104                GLTFGKPEEKMGLHAIPTTTAHYDNALVSAQRRIGAEGQGLQIAFSALDS
MSMEG_0108|M.smegmatis_MC2_155      GLSFGKPEEKMGLHAVPTTSAFYDNARIDADRLIGTEGQGLSIAFSALDS
TH_4603|M.thermoresistible__bu      GLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAFSALDS
                                    *: .*  *.*:*::. **:  .::.. : .:* **  * *:. *: :** 

MMAR_1262|M.marinum_M               TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGKSISDFQAVQFMLADMAMK
MUL_2626|M.ulcerans_Agy99           TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGKSISDFQAVQFMLADMAMK
Mb3302c|M.bovis_AF2122/97           TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMK
Rv3274c|M.tuberculosis_H37Rv        TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMK
MLBr_00737|M.leprae_Br4923          TRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMK
MAB_3618c|M.abscessus_ATCC_199      TRPTIGAQALGIAQGALDQAIAYTKDRKQFGKSISDFQGVQFMLADMAMK
Mvan_1476|M.vanbaalenii_PYR-1       GRLGIAAVAVGLAQAALDAAVDYSQERTTFGRKIIDHQGLAFLLADMAAA
Mflv_4943|M.gilvum_PYR-GCK          GRLGIAAVAVGLAQAALDEAVAYSQERTTFGRKIIDHQGLAFLLADMAAA
MAV_2668|M.avium_104                GRLGIAAVAVGLAQAALDEAVSYAQQRTTFGRKIIDHQGLAFLLADMAAA
MSMEG_0108|M.smegmatis_MC2_155      GRLGIAAVAVGIAQAALDEAVRYAHERTTFGRKIIDHQGLGFLLADMAAA
TH_4603|M.thermoresistible__bu      GRLGIAAVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADMAAA
                                     *  *.* * *:**.*** *: *:::*. **..*  .*.: *:*****  

MMAR_1262|M.marinum_M               VESARLMVYSAAARAERGESNLGFISAASKCLASDVAMEVTTDAVQLFGG
MUL_2626|M.ulcerans_Agy99           VESARLMVYSAAARAERGESNLGFISAASKCLASDVAMEVTTDAVQLFGG
Mb3302c|M.bovis_AF2122/97           VEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLFGG
Rv3274c|M.tuberculosis_H37Rv        VEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLFGG
MLBr_00737|M.leprae_Br4923          VEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLFGG
MAB_3618c|M.abscessus_ATCC_199      VEAARLMVYTAAARAERGEKNLGFISSASKCFASDVAMEVTTDAVQLFGG
Mvan_1476|M.vanbaalenii_PYR-1       VDAARATYLDAARRRDAGLP-YSRHASVAKLTATDAAMKVTTDAVQVFGG
Mflv_4943|M.gilvum_PYR-GCK          VDSARATYLDAARRRDAGLP-YSRHASVAKLVATDAAMKVTTDAVQVLGG
MAV_2668|M.avium_104                VDSARATYLDAARRRDAGLP-YSRNASVAKLIATDAAMKVTTDAVQVFGG
MSMEG_0108|M.smegmatis_MC2_155      VVSARATYLDAARRRDAGLP-YSSQASVAKLVATDAAMKVTTDAVQVLGG
TH_4603|M.thermoresistible__bu      VATARATYLDAARRRDQGRP-YSQQASIAKLTATDAAMKVTTDAVQVFGG
                                    * :**     ** * : *    .  :: :*  *:* **:*******::**

MMAR_1262|M.marinum_M               AGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR-
MUL_2626|M.ulcerans_Agy99           AGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR-
Mb3302c|M.bovis_AF2122/97           AGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-
Rv3274c|M.tuberculosis_H37Rv        AGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-
MLBr_00737|M.leprae_Br4923          AGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-
MAB_3618c|M.abscessus_ATCC_199      AGYTTDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLTS
Mvan_1476|M.vanbaalenii_PYR-1       AGYTRDYRVERYMREAKITQIFEGTNQIQRLVISRHLARD
Mflv_4943|M.gilvum_PYR-GCK          AGYTRDYRVERYMREAKITQIFEGTNQIQRLVISRHLTRG
MAV_2668|M.avium_104                YGYTRDYRVERYMREAKITQIFEGTNQIQRLVIGRSLVGS
MSMEG_0108|M.smegmatis_MC2_155      VGYTRDFRVERYMREAKITQIFEGTNQIQRLVISRGLGT-
TH_4603|M.thermoresistible__bu      VGYTRDYRVERYMREAKIMQIFEGTNQIQRLVIARGLTR-
                                     *** *: *** **:*** **:********:*:.* *