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AASATRSPWYSSLFIQLLVAIVAGIVVGWLWPDVGGSLKPLADGFIKLIKMLIAPIIFCTVVLGIAHVGD LKSVGRIGVKALIYFEAITTFALLFGLVVGNVVKPGAGFNIDAQTLATGAEAVAAKTGDGELPHTVEFLL NIIPSSVVSAFAENALLQVLFFAVLFGLGLAKFGEHGPPVVLEFIDHLSHIFFTVIGWIMRLAPLGAFGA MAYIIGQYGIGSLGSYAKLIAACYVAAALFIVILAVVTKVFAGVNLWKFFLYIKDEMFLALGTASTEVVL PRVMAKLTNAGCSRTTTGLVVPTGYSFNLDGATLYLSICVLFLAQALGVDLSLGEQIMAVLVLMLTSKGM AGVPGSSFLALSATVAAIGHGAIPVAAVALLLGADRIMDSMRVSVNLLGNCVATLVVAAWEGQLDRERMR KVLAGEDVPPLDELAEADGSGRGTPVGAQAGSRD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_4501 | - | - | 100% (455) | sodium:dicarboxylate symporter |
M. smegmatis MC2 155 | MSMEG_5302 | - | 2e-87 | 41.04% (441) | aerobic C4-dicarboxylate transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2470 | dctA | 2e-79 | 37.05% (448) | C4-dicarboxylate-transport transmembrane protein DctA |
M. gilvum PYR-GCK | Mflv_1323 | - | 3e-83 | 40.32% (434) | sodium:dicarboxylate symporter |
M. tuberculosis H37Rv | Rv2443 | dctA | 2e-79 | 37.05% (448) | C4-dicarboxylate-transport transmembrane protein DctA |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2938 | - | 0.0 | 85.88% (425) | sodium:dicarboxylate symporter |
M. marinum M | MMAR_3814 | dctA | 1e-75 | 36.18% (434) | C4-dicarboxylate-transport transmembrane protein DctA |
M. avium 104 | - | - | - | - | - |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_4696 | - | 1e-91 | 42.40% (434) | sodium:dicarboxylate symporter |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1323|M.gilvum_PYR-GCK MAATDDDAG--TDTTKKTGKRDRTHWLYILVIVAVVAGIVVGLVAPETAA Mvan_4696|M.vanbaalenii_PYR-1 -MTTRMDSP--TPPEAPRRKRDRTHWLYIAVIVAVVAGVAVGILAPEVGK Mb2470|M.bovis_AF2122/97 -MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGK Rv2443|M.tuberculosis_H37Rv -MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGK MMAR_3814|M.marinum_M -MTTPLDQPPATDPRASKKRPDRTRWLYFAVIGAVILGVIAGLAVPSIGP MSMEG_4501|M.smegmatis_MC2_155 -------------MAASATRSPWYSSLFIQLLVAIVAGIVVGWLWPDVGG MAB_2938|M.abscessus_ATCC_1997 -MPTAIEVP-ASEMVRLANKPPWYRSLFVQLLVAIVAGVVIGWLWPGLGA *:. :: *:: *: * * . Mflv_1323|M.gilvum_PYR-GCK SLGVLGELFVKLIKMMTVPVIFCTVVLGIGKVRAAASVGKVGGLAIGYFL Mvan_4696|M.vanbaalenii_PYR-1 SVGVLGTMFVALIKMMIAPVIFCTIVLGIGSVRKAATVGKVGGLAFLYFL Mb2470|M.bovis_AF2122/97 SLTVLGTVFVNLIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYFL Rv2443|M.tuberculosis_H37Rv SLTVLGTVFVNLIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYFL MMAR_3814|M.marinum_M HVAVLGTTFVNLITMMVAPVIFCTIVLGIGSLNRAALLGKVGGLAFLYFL MSMEG_4501|M.smegmatis_MC2_155 SLKPLADGFIKLIKMLIAPIIFCTVVLGIAHVGDLKSVGRIGVKALIYFE MAB_2938|M.abscessus_ATCC_1997 DLRPLADGFIKLIKMLIAPIIFCTVVLGIAHVGDLKSVGRIGVKALIYFE : *. *: **.*: .*:****:****. : :*::* *: ** Mflv_1323|M.gilvum_PYR-GCK VMSTIALAIGLVVGNLISPGTGLNVP-HDPGKGAELAGEAESAG---GTM Mvan_4696|M.vanbaalenii_PYR-1 VMSTFALAIGLVVGNLLHPGSGLQVSDTAAGKGAELADKAHEAG---GLL Mb2470|M.bovis_AF2122/97 TMSSVALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAAESH---GIA Rv2443|M.tuberculosis_H37Rv TMSSVALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAAESH---GIA MMAR_3814|M.marinum_M VMSTAALGIGLFVGNLIGTVRGLHLSVESMGSGVEVADAAPPSG---WMH MSMEG_4501|M.smegmatis_MC2_155 AITTFALLFGLVVGNVVKPGAGFNIDAQTLATGAEAVAAKTGDGELPHTV MAB_2938|M.abscessus_ATCC_1997 AVTTFALLFGLLVGNLAKPGAGFHIDAGTLATGADAIAKKTNNGELPHTV .::: ** :**.***: . .::: ..*. Mflv_1323|M.gilvum_PYR-GCK AFISDIIPSTLFSAVTEGNVLQALFVALLVGFGIQGIGAHG-ESLLRGIE Mvan_4696|M.vanbaalenii_PYR-1 DFVQGIIPTTMFSSLTEGSVLQALFIALLVGFALQGLGTAG-EPILRGIE Mb2470|M.bovis_AF2122/97 GFIQQIIPRSLPSALTEGNVLQVLLVALLVGFAVQGLGPAG-ESILRAVE Rv2443|M.tuberculosis_H37Rv GFIQQIIPRSLPSALTEGNVLQVLLVALLVGFAVQGLGPAG-ESILRAVE MMAR_3814|M.marinum_M GLLDQVIPTSLLSGLTNGNVLQALFVALLVGFAVQGMGAAG-EPILRSVE MSMEG_4501|M.smegmatis_MC2_155 EFLLNIIPSSVVSAFAENALLQVLFFAVLFGLGLAKFGEHGPPVVLEFID MAB_2938|M.abscessus_ATCC_1997 EFLLGIIPSSIVSAFAENALLQVLFFAVLFGLALAKFGESGPPVVLEFID :: :** :: *..::. :**.*:.*:*.*:.: :* * :*. :: Mflv_1323|M.gilvum_PYR-GCK ALQKLVFRILIGVLWLAPIGAFGAIAEVVGDTGFDAVIQLGVLMAAFYIT Mvan_4696|M.vanbaalenii_PYR-1 HLQKLVFKVLVMILWLAPIGAFGAIANVVGQTGWAAVGQLMALMLGFYLT Mb2470|M.bovis_AF2122/97 NLQKLVFKVLVMVLWLAPIGAFGAIANIVATTGFNAVTNLLLLMAGFYLT Rv2443|M.tuberculosis_H37Rv NLQKLVFKVLVMVLWLAPIGAFGAIANIVATTGFNAVTNLLLLMAGFYLT MMAR_3814|M.marinum_M YLQKLVFKVLGMLLWLAPIGAFGWIASIIGATGWGAVANLLILLVGFYLT MSMEG_4501|M.smegmatis_MC2_155 HLSHIFFTVIGWIMRLAPLGAFGAMAYIIGQYGIGSLGSYAKLIAACYVA MAB_2938|M.abscessus_ATCC_1997 HLSHIFFTIIGWIMRLAPVGALGAMAYIVGQYGIGSLSSYGKLIAACYAA *.::.* :: :: ***:**:* :* ::. * :: . *: . * : Mflv_1323|M.gilvum_PYR-GCK CVIFIFGVLGALLWAVARVSIFKLARYLAREYLLIVATSSSESALPRLIA Mvan_4696|M.vanbaalenii_PYR-1 CAIFVFGVLGALLRVVSGVSIFKLVRYLAREYLLIVSTSSSESALPRLIA Mb2470|M.bovis_AF2122/97 CVVFVFGVLGVLLRIVSGLSIFRLLRYLAREYLLIFATSSSEVVLPRLIT Rv2443|M.tuberculosis_H37Rv CVVFVFGVLGVLLRIVSGLSIFRLLRYLAREYLLIFATSSSEVVLPRLIT MMAR_3814|M.marinum_M CAVFVFGVLGVLLYVVSGVSIFRLVRYLAREYLLIFATSSSEAVLPRLVA MSMEG_4501|M.smegmatis_MC2_155 AALFIV-ILAVVTKVFAGVNLWKFFLYIKDEMFLALGTASTEVVLPRVMA MAB_2938|M.abscessus_ATCC_1997 ALLFIG-VLAVIARLFAGVNLWRFVVYIKDELFLALGTASTEVVLPRIMT . :*: :*..: .: :.:::: *: * :* ..*:*:* .***::: Mflv_1323|M.gilvum_PYR-GCK KMEHAGVKPATVGIVVPTGYSFNLDGTAIYLTMASLFIADALGDPLSIPE Mvan_4696|M.vanbaalenii_PYR-1 KMEHLGVDRSTVGVVVPTGYSFNLDGTAIYLTMASLFIAGALGDPLSLGE Mb2470|M.bovis_AF2122/97 KMKHLGVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHRLTWGE Rv2443|M.tuberculosis_H37Rv KMKHLGVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHRLTWGE MMAR_3814|M.marinum_M KMKHLGVEPATVGVVVPVGYSFNLDGTALYLTMASLFIADALGRPLAWGE MSMEG_4501|M.smegmatis_MC2_155 KLTNAGCSRTTTGLVVPTGYSFNLDGATLYLSICVLFLAQALGVDLSLGE MAB_2938|M.abscessus_ATCC_1997 KLNHAGCSKTTTGLVIPTGYSFNLDGATLYLSICVLFLAQALGVNLTLGE *: : * . :*.*:*:*.********:::**::. **:* *:* *: * Mflv_1323|M.gilvum_PYR-GCK QLGLLAFMIIASKGAAGVSGAGLATLAA--GLQSHRPELLDGVGIIVGID Mvan_4696|M.vanbaalenii_PYR-1 QIGLLVFMIVASKGAAGVTGAGLATLAG--GLQAHRPDLLDGVGLIVGID Mb2470|M.bovis_AF2122/97 QIALLAFMIIASKGAAGVSGAGLATLAG--GLQAHRPELLDGVGLIVGID Rv2443|M.tuberculosis_H37Rv QIALLAFMIIASKGAAGVSGAGLATLAG--GLQAHRPELLDGVGLIVGID MMAR_3814|M.marinum_M QISLLVFMIFASKGAAGVSGAGLAALAS--GLQAYRPELLGGVALVAGTD MSMEG_4501|M.smegmatis_MC2_155 QIMAVLVLMLTSKGMAGVPGSSFLALSATVAAIGHGAIPVAAVALLLGAD MAB_2938|M.abscessus_ATCC_1997 QITAVLVLMLTSKGMAGVPGSSFLALSATVAAIGHGAIPVAAVALLLGAD *: : .::.:*** ***.*:.: :*:. . .: . : .*.:: * * Mflv_1323|M.gilvum_PYR-GCK RFMSEARALTNFSGNAVATVLVGSWTDSVDKNRLNEVLDGDRPFDEATML Mvan_4696|M.vanbaalenii_PYR-1 RFMSEARALTNFSGNAVATLLVGSWTRTIDRDKVNSVLAGDDPFDELTML Mb2470|M.bovis_AF2122/97 RFMSEARSLTNFSGNAVATILVASWTKTIDLSKADEVLRGRDPFDESTMV Rv2443|M.tuberculosis_H37Rv RFMSEARSLTNFSGNAVATILVASWTKTIDLSKADEVLRGRDPFDESTMV MMAR_3814|M.marinum_M TFMKEARSLTNFSGNAVATILVGWWTKTIDRAKVDAVLHGRDPFDEWTMI MSMEG_4501|M.smegmatis_MC2_155 RIMDSMRVSVNLLGNCVATLVVAAWEGQLDRERMRKVLAGEDVPPLDELA MAB_2938|M.abscessus_ATCC_1997 RIMDSMRVSVNLLGNCVATLVVAQWEGQLDKDRMCKVLAGQQVV------ :*.. * .*: **.***::*. * :* : ** * Mflv_1323|M.gilvum_PYR-GCK DDDDAEDRTTIDRTARSGAPTAG------------------------- Mvan_4696|M.vanbaalenii_PYR-1 DSDHGS-RAQEPAQEKIPAPV--------------------------- Mb2470|M.bovis_AF2122/97 DPHDEEPPAATPHGGGVPTNPALCDFEQVSLGGLVGRPAGPQRADVDG Rv2443|M.tuberculosis_H37Rv DPHDEEPPAATPHGGGVPTNPALCDFEQVSLGGLVGRPAGPQRADVDG MMAR_3814|M.marinum_M D-RDDAPPTGVAES---------------------------------- MSMEG_4501|M.smegmatis_MC2_155 EADGSGRGTPVGAQAGSRD----------------------------- MAB_2938|M.abscessus_ATCC_1997 -------NEPEGESAAAHP-----------------------------