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MPTAIEVPASEMVRLANKPPWYRSLFVQLLVAIVAGVVIGWLWPGLGADLRPLADGFIKLIKMLIAPIIF CTVVLGIAHVGDLKSVGRIGVKALIYFEAVTTFALLFGLLVGNLAKPGAGFHIDAGTLATGADAIAKKTN NGELPHTVEFLLGIIPSSIVSAFAENALLQVLFFAVLFGLALAKFGESGPPVVLEFIDHLSHIFFTIIGW IMRLAPVGALGAMAYIVGQYGIGSLSSYGKLIAACYAAALLFIGVLAVIARLFAGVNLWRFVVYIKDELF LALGTASTEVVLPRIMTKLNHAGCSKTTTGLVIPTGYSFNLDGATLYLSICVLFLAQALGVNLTLGEQIT AVLVLMLTSKGMAGVPGSSFLALSATVAAIGHGAIPVAAVALLLGADRIMDSMRVSVNLLGNCVATLVVA QWEGQLDKDRMCKVLAGQQVVNEPEGESAAAHP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2938 | - | - | 100% (453) | sodium:dicarboxylate symporter |
| M. abscessus ATCC 19977 | MAB_1540 | - | 1e-86 | 38.91% (442) | sodium:dicarboxylate symporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2470 | dctA | 1e-82 | 39.30% (430) | C4-dicarboxylate-transport transmembrane protein DctA |
| M. gilvum PYR-GCK | Mflv_1323 | - | 6e-80 | 39.57% (422) | sodium:dicarboxylate symporter |
| M. tuberculosis H37Rv | Rv2443 | dctA | 1e-82 | 39.30% (430) | C4-dicarboxylate-transport transmembrane protein DctA |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3814 | dctA | 1e-75 | 35.28% (445) | C4-dicarboxylate-transport transmembrane protein DctA |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_4501 | - | 0.0 | 85.88% (425) | sodium:dicarboxylate symporter |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4696 | - | 1e-88 | 40.18% (443) | sodium:dicarboxylate symporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1323|M.gilvum_PYR-GCK MAATDDDAG--TDTTKKTGKRDRTHWLYILVIVAVVAGIVVGLVAPETAA
Mvan_4696|M.vanbaalenii_PYR-1 -MTTRMDSP--TPPEAPRRKRDRTHWLYIAVIVAVVAGVAVGILAPEVGK
Mb2470|M.bovis_AF2122/97 -MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGK
Rv2443|M.tuberculosis_H37Rv -MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGK
MMAR_3814|M.marinum_M -MTTPLDQPPATDPRASKKRPDRTRWLYFAVIGAVILGVIAGLAVPSIGP
MAB_2938|M.abscessus_ATCC_1997 -MPTAIEVP-ASEMVRLANKPPWYRSLFVQLLVAIVAGVVIGWLWPGLGA
MSMEG_4501|M.smegmatis_MC2_155 -------------MAASATRSPWYSSLFIQLLVAIVAGIVVGWLWPDVGG
*:. :: *:: *: * * .
Mflv_1323|M.gilvum_PYR-GCK SLGVLGELFVKLIKMMTVPVIFCTVVLGIGKVRAAASVGKVGGLAIGYFL
Mvan_4696|M.vanbaalenii_PYR-1 SVGVLGTMFVALIKMMIAPVIFCTIVLGIGSVRKAATVGKVGGLAFLYFL
Mb2470|M.bovis_AF2122/97 SLTVLGTVFVNLIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYFL
Rv2443|M.tuberculosis_H37Rv SLTVLGTVFVNLIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYFL
MMAR_3814|M.marinum_M HVAVLGTTFVNLITMMVAPVIFCTIVLGIGSLNRAALLGKVGGLAFLYFL
MAB_2938|M.abscessus_ATCC_1997 DLRPLADGFIKLIKMLIAPIIFCTVVLGIAHVGDLKSVGRIGVKALIYFE
MSMEG_4501|M.smegmatis_MC2_155 SLKPLADGFIKLIKMLIAPIIFCTVVLGIAHVGDLKSVGRIGVKALIYFE
: *. *: **.*: .*:****:****. : :*::* *: **
Mflv_1323|M.gilvum_PYR-GCK VMSTIALAIGLVVGNLISPGTGLNVP-HDPGKGAELAGEAESAG---GTM
Mvan_4696|M.vanbaalenii_PYR-1 VMSTFALAIGLVVGNLLHPGSGLQVSDTAAGKGAELADKAHEAG---GLL
Mb2470|M.bovis_AF2122/97 TMSSVALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAAESH---GIA
Rv2443|M.tuberculosis_H37Rv TMSSVALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAAESH---GIA
MMAR_3814|M.marinum_M VMSTAALGIGLFVGNLIGTVRGLHLSVESMGSGVEVADAAPPSG---WMH
MAB_2938|M.abscessus_ATCC_1997 AVTTFALLFGLLVGNLAKPGAGFHIDAGTLATGADAIAKKTNNGELPHTV
MSMEG_4501|M.smegmatis_MC2_155 AITTFALLFGLVVGNVVKPGAGFNIDAQTLATGAEAVAAKTGDGELPHTV
.::: ** :**.***: . .::: ..*.
Mflv_1323|M.gilvum_PYR-GCK AFISDIIPSTLFSAVTEGNVLQALFVALLVGFGIQGIGAHG-ESLLRGIE
Mvan_4696|M.vanbaalenii_PYR-1 DFVQGIIPTTMFSSLTEGSVLQALFIALLVGFALQGLGTAG-EPILRGIE
Mb2470|M.bovis_AF2122/97 GFIQQIIPRSLPSALTEGNVLQVLLVALLVGFAVQGLGPAG-ESILRAVE
Rv2443|M.tuberculosis_H37Rv GFIQQIIPRSLPSALTEGNVLQVLLVALLVGFAVQGLGPAG-ESILRAVE
MMAR_3814|M.marinum_M GLLDQVIPTSLLSGLTNGNVLQALFVALLVGFAVQGMGAAG-EPILRSVE
MAB_2938|M.abscessus_ATCC_1997 EFLLGIIPSSIVSAFAENALLQVLFFAVLFGLALAKFGESGPPVVLEFID
MSMEG_4501|M.smegmatis_MC2_155 EFLLNIIPSSVVSAFAENALLQVLFFAVLFGLGLAKFGEHGPPVVLEFID
:: :** :: *..::. :**.*:.*:*.*:.: :* * :*. ::
Mflv_1323|M.gilvum_PYR-GCK ALQKLVFRILIGVLWLAPIGAFGAIAEVVGDTGFDAVIQLGVLMAAFYIT
Mvan_4696|M.vanbaalenii_PYR-1 HLQKLVFKVLVMILWLAPIGAFGAIANVVGQTGWAAVGQLMALMLGFYLT
Mb2470|M.bovis_AF2122/97 NLQKLVFKVLVMVLWLAPIGAFGAIANIVATTGFNAVTNLLLLMAGFYLT
Rv2443|M.tuberculosis_H37Rv NLQKLVFKVLVMVLWLAPIGAFGAIANIVATTGFNAVTNLLLLMAGFYLT
MMAR_3814|M.marinum_M YLQKLVFKVLGMLLWLAPIGAFGWIASIIGATGWGAVANLLILLVGFYLT
MAB_2938|M.abscessus_ATCC_1997 HLSHIFFTIIGWIMRLAPVGALGAMAYIVGQYGIGSLSSYGKLIAACYAA
MSMEG_4501|M.smegmatis_MC2_155 HLSHIFFTVIGWIMRLAPLGAFGAMAYIIGQYGIGSLGSYAKLIAACYVA
*.::.* :: :: ***:**:* :* ::. * :: . *: . * :
Mflv_1323|M.gilvum_PYR-GCK CVIFIFGVLGALLWAVARVSIFKLARYLAREYLLIVATSSSESALPRLIA
Mvan_4696|M.vanbaalenii_PYR-1 CAIFVFGVLGALLRVVSGVSIFKLVRYLAREYLLIVSTSSSESALPRLIA
Mb2470|M.bovis_AF2122/97 CVVFVFGVLGVLLRIVSGLSIFRLLRYLAREYLLIFATSSSEVVLPRLIT
Rv2443|M.tuberculosis_H37Rv CVVFVFGVLGVLLRIVSGLSIFRLLRYLAREYLLIFATSSSEVVLPRLIT
MMAR_3814|M.marinum_M CAVFVFGVLGVLLYVVSGVSIFRLVRYLAREYLLIFATSSSEAVLPRLVA
MAB_2938|M.abscessus_ATCC_1997 ALLFIG-VLAVIARLFAGVNLWRFVVYIKDELFLALGTASTEVVLPRIMT
MSMEG_4501|M.smegmatis_MC2_155 AALFIV-ILAVVTKVFAGVNLWKFFLYIKDEMFLALGTASTEVVLPRVMA
. :*: :*..: .: :.:::: *: * :* ..*:*:* .***:::
Mflv_1323|M.gilvum_PYR-GCK KMEHAGVKPATVGIVVPTGYSFNLDGTAIYLTMASLFIADALGDPLSIPE
Mvan_4696|M.vanbaalenii_PYR-1 KMEHLGVDRSTVGVVVPTGYSFNLDGTAIYLTMASLFIAGALGDPLSLGE
Mb2470|M.bovis_AF2122/97 KMKHLGVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHRLTWGE
Rv2443|M.tuberculosis_H37Rv KMKHLGVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHRLTWGE
MMAR_3814|M.marinum_M KMKHLGVEPATVGVVVPVGYSFNLDGTALYLTMASLFIADALGRPLAWGE
MAB_2938|M.abscessus_ATCC_1997 KLNHAGCSKTTTGLVIPTGYSFNLDGATLYLSICVLFLAQALGVNLTLGE
MSMEG_4501|M.smegmatis_MC2_155 KLTNAGCSRTTTGLVVPTGYSFNLDGATLYLSICVLFLAQALGVDLSLGE
*: : * . :*.*:*:*.********:::**::. **:* *:* *: *
Mflv_1323|M.gilvum_PYR-GCK QLGLLAFMIIASKGAAGVSGAGLATLAA--GLQSHRPELLDGVGIIVGID
Mvan_4696|M.vanbaalenii_PYR-1 QIGLLVFMIVASKGAAGVTGAGLATLAG--GLQAHRPDLLDGVGLIVGID
Mb2470|M.bovis_AF2122/97 QIALLAFMIIASKGAAGVSGAGLATLAG--GLQAHRPELLDGVGLIVGID
Rv2443|M.tuberculosis_H37Rv QIALLAFMIIASKGAAGVSGAGLATLAG--GLQAHRPELLDGVGLIVGID
MMAR_3814|M.marinum_M QISLLVFMIFASKGAAGVSGAGLAALAS--GLQAYRPELLGGVALVAGTD
MAB_2938|M.abscessus_ATCC_1997 QITAVLVLMLTSKGMAGVPGSSFLALSATVAAIGHGAIPVAAVALLLGAD
MSMEG_4501|M.smegmatis_MC2_155 QIMAVLVLMLTSKGMAGVPGSSFLALSATVAAIGHGAIPVAAVALLLGAD
*: : .::.:*** ***.*:.: :*:. . .: . : .*.:: * *
Mflv_1323|M.gilvum_PYR-GCK RFMSEARALTNFSGNAVATVLVGSWTDSVDKNRLNEVLDGDRPFDEATML
Mvan_4696|M.vanbaalenii_PYR-1 RFMSEARALTNFSGNAVATLLVGSWTRTIDRDKVNSVLAGDDPFDELTML
Mb2470|M.bovis_AF2122/97 RFMSEARSLTNFSGNAVATILVASWTKTIDLSKADEVLRGRDPFDESTMV
Rv2443|M.tuberculosis_H37Rv RFMSEARSLTNFSGNAVATILVASWTKTIDLSKADEVLRGRDPFDESTMV
MMAR_3814|M.marinum_M TFMKEARSLTNFSGNAVATILVGWWTKTIDRAKVDAVLHGRDPFDEWTMI
MAB_2938|M.abscessus_ATCC_1997 RIMDSMRVSVNLLGNCVATLVVAQWEGQLDKDRMCKVLAGQQVV------
MSMEG_4501|M.smegmatis_MC2_155 RIMDSMRVSVNLLGNCVATLVVAAWEGQLDRERMRKVLAGEDVPPLDELA
:*.. * .*: **.***::*. * :* : ** *
Mflv_1323|M.gilvum_PYR-GCK DDDDAEDRTTIDRTARSGAPTAG-------------------------
Mvan_4696|M.vanbaalenii_PYR-1 DSDHGS-RAQEPAQEKIPAPV---------------------------
Mb2470|M.bovis_AF2122/97 DPHDEEPPAATPHGGGVPTNPALCDFEQVSLGGLVGRPAGPQRADVDG
Rv2443|M.tuberculosis_H37Rv DPHDEEPPAATPHGGGVPTNPALCDFEQVSLGGLVGRPAGPQRADVDG
MMAR_3814|M.marinum_M D-RDDAPPTGVAES----------------------------------
MAB_2938|M.abscessus_ATCC_1997 -------NEPEGESAAAHP-----------------------------
MSMEG_4501|M.smegmatis_MC2_155 EADGSGRGTPVGAQAGSRD-----------------------------