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TTPLDQPPATDPRASKKRPDRTRWLYFAVIGAVILGVIAGLAVPSIGPHVAVLGTTFVNLITMMVAPVIF CTIVLGIGSLNRAALLGKVGGLAFLYFLVMSTAALGIGLFVGNLIGTVRGLHLSVESMGSGVEVADAAPP SGWMHGLLDQVIPTSLLSGLTNGNVLQALFVALLVGFAVQGMGAAGEPILRSVEYLQKLVFKVLGMLLWL APIGAFGWIASIIGATGWGAVANLLILLVGFYLTCAVFVFGVLGVLLYVVSGVSIFRLVRYLAREYLLIF ATSSSEAVLPRLVAKMKHLGVEPATVGVVVPVGYSFNLDGTALYLTMASLFIADALGRPLAWGEQISLLV FMIFASKGAAGVSGAGLAALASGLQAYRPELLGGVALVAGTDTFMKEARSLTNFSGNAVATILVGWWTKT IDRAKVDAVLHGRDPFDEWTMIDRDDAPPTGVAES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3814 | dctA | - | 100% (456) | C4-dicarboxylate-transport transmembrane protein DctA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2470 | dctA | 1e-177 | 71.62% (451) | C4-dicarboxylate-transport transmembrane protein DctA |
| M. gilvum PYR-GCK | Mflv_1323 | - | 1e-152 | 61.85% (443) | sodium:dicarboxylate symporter |
| M. tuberculosis H37Rv | Rv2443 | dctA | 1e-177 | 71.62% (451) | C4-dicarboxylate-transport transmembrane protein DctA |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1540 | - | 1e-159 | 63.47% (438) | sodium:dicarboxylate symporter |
| M. avium 104 | MAV_3974 | - | 0.0001 | 27.92% (265) | permease of the major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_5302 | - | 1e-167 | 67.79% (444) | aerobic C4-dicarboxylate transport protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4696 | - | 1e-172 | 69.06% (446) | sodium:dicarboxylate symporter |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5302|M.smegmatis_MC2_155 MSTTLDRQ--PEPAPPRR-RDRTHWLYIAVIVAVVAGVAVGLLAPEVGKS
Mvan_4696|M.vanbaalenii_PYR-1 MTTRMDSP--TPPEAPRRKRDRTHWLYIAVIVAVVAGVAVGILAPEVGKS
MAB_1540|M.abscessus_ATCC_1997 MTATEPAT--SESTPPKKHKDRTHWLYIAVVVAVALGVAVGMLWPGFGRS
Mflv_1323|M.gilvum_PYR-GCK MAATDDDAG-TDTTKKTGKRDRTHWLYILVIVAVVAGIVVGLVAPETAAS
Mb2470|M.bovis_AF2122/97 MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGKS
Rv2443|M.tuberculosis_H37Rv MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGKS
MMAR_3814|M.marinum_M MTTPLDQPPATDPRASKKRPDRTRWLYFAVIGAVILGVIAGLAVPSIGPH
MAV_3974|M.avium_104 -MVALGYG-VISPALPTFARSFGVSIKAVTFLVTVFSLSRLCFAPISGLL
. . : .. .. .: * .
MSMEG_5302|M.smegmatis_MC2_155 VGVLG--TMFVNLIKMMIGPVIFCTIVLGIGSVRKAATVGKVGGLAFTYF
Mvan_4696|M.vanbaalenii_PYR-1 VGVLG--TMFVALIKMMIAPVIFCTIVLGIGSVRKAATVGKVGGLAFLYF
MAB_1540|M.abscessus_ATCC_1997 VGVLG--EIFVSLIKMMISPVIFCTIVLGIGSVRKAASVGRVGGLAFVYF
Mflv_1323|M.gilvum_PYR-GCK LGVLG--ELFVKLIKMMTVPVIFCTVVLGIGKVRAAASVGKVGGLAIGYF
Mb2470|M.bovis_AF2122/97 LTVLG--TVFVNLIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYF
Rv2443|M.tuberculosis_H37Rv LTVLG--TVFVNLIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYF
MMAR_3814|M.marinum_M VAVLG--TTFVNLITMMVAPVIFCTIVLGIGSLNRAALLGKVGGLAFLYF
MAV_3974|M.avium_104 TERLGERRIYIGGLLIVAVSTAACAFSQAYWQLMLCRVFSGVG----STM
** :: : :: .. *:. . .: . .. ** :
MSMEG_5302|M.smegmatis_MC2_155 LVMSTFALAIGLVVGNVLHPGTGMHLTESAAGKGAELAETAHEAGGLMDF
Mvan_4696|M.vanbaalenii_PYR-1 LVMSTFALAIGLVVGNLLHPGSGLQVSDTAAGKGAELADKAHEAGGLLDF
MAB_1540|M.abscessus_ATCC_1997 LAMSTVALAIGLVVGNLLAPGTGLHLSGSNQGAGAKYVDQAHAAGGTWHF
Mflv_1323|M.gilvum_PYR-GCK LVMSTIALAIGLVVGNLISPGTGLNVP-HDPGKGAELAGEAESAGGTMAF
Mb2470|M.bovis_AF2122/97 LTMSSVALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAAESHGIAGF
Rv2443|M.tuberculosis_H37Rv LTMSSVALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAAESHGIAGF
MMAR_3814|M.marinum_M LVMSTAALGIGLFVGNLIGTVRGLHLSVESMGSGVEVADAAPPSGWMHGL
MAV_3974|M.avium_104 FYVSALGLMIHISPADARGRIAGLFTTSFMVG-----AVGGPAVGGLAAG
: :*: .* * : .: .: * . .
MSMEG_5302|M.smegmatis_MC2_155 VQGIIPETLFSALTAGSVLQALFVALLVGFALQAMGSAGEPVLRGIVHLQ
Mvan_4696|M.vanbaalenii_PYR-1 VQGIIPTTMFSSLTEGSVLQALFIALLVGFALQGLGTAGEPILRGIEHLQ
MAB_1540|M.abscessus_ATCC_1997 IKSIVPETMFSALTSGSVLQTLFIALLVGFAVQALGGTGESIVRGVGMLQ
Mflv_1323|M.gilvum_PYR-GCK ISDIIPSTLFSAVTEGNVLQALFVALLVGFGIQGIGAHGESLLRGIEALQ
Mb2470|M.bovis_AF2122/97 IQQIIPRSLPSALTEGNVLQVLLVALLVGFAVQGLGPAGESILRAVENLQ
Rv2443|M.tuberculosis_H37Rv IQQIIPRSLPSALTEGNVLQVLLVALLVGFAVQGLGPAGESILRAVENLQ
MMAR_3814|M.marinum_M LDQVIPTSLLSGLTNGNVLQALFVALLVGFAVQGMGAAGEPILRSVEYLQ
MAV_3974|M.avium_104 WGLTAPFVVYGVAMLG-----VALVLFLGLRNSALAAPPPPTRSTVTMRE
* : . * : :.*::*: ..:. . : :
MSMEG_5302|M.smegmatis_MC2_155 KLVFKVLAMILWLAPIGAFGAIANVVGQTGWTAVTQLLALMFGFYVTCFV
Mvan_4696|M.vanbaalenii_PYR-1 KLVFKVLVMILWLAPIGAFGAIANVVGQTGWAAVGQLMALMLGFYLTCAI
MAB_1540|M.abscessus_ATCC_1997 KLVFKVLIMVLWLAPIGAFGAIANVVGQTGWDAVKELGTLMLGFYVTCAI
Mflv_1323|M.gilvum_PYR-GCK KLVFRILIGVLWLAPIGAFGAIAEVVGDTGFDAVIQLGVLMAAFYITCVI
Mb2470|M.bovis_AF2122/97 KLVFKVLVMVLWLAPIGAFGAIANIVATTGFNAVTNLLLLMAGFYLTCVV
Rv2443|M.tuberculosis_H37Rv KLVFKVLVMVLWLAPIGAFGAIANIVATTGFNAVTNLLLLMAGFYLTCVV
MMAR_3814|M.marinum_M KLVFKVLGMLLWLAPIGAFGWIASIIGATGWGAVANLLILLVGFYLTCAV
MAV_3974|M.avium_104 ALRVRAYQSALLSN------------FATGWSAFGLRMALVPLFVSDVMG
* .: * **: *. *: *
MSMEG_5302|M.smegmatis_MC2_155 FVFGVLGVLMRAVAGVSIFKLVR------YLAREYLLIVSTSSS--ESAL
Mvan_4696|M.vanbaalenii_PYR-1 FVFGVLGALLRVVSGVSIFKLVR------YLAREYLLIVSTSSS--ESAL
MAB_1540|M.abscessus_ATCC_1997 FIFGVLGTLLWAVSRVSIFRLVR------YLAREYLLIVSTSSS--ESAL
Mflv_1323|M.gilvum_PYR-GCK FIFGVLGALLWAVARVSIFKLAR------YLAREYLLIVATSSS--ESAL
Mb2470|M.bovis_AF2122/97 FVFGVLGVLLRIVSGLSIFRLLR------YLAREYLLIFATSSS--EVVL
Rv2443|M.tuberculosis_H37Rv FVFGVLGVLLRIVSGLSIFRLLR------YLAREYLLIFATSSS--EVVL
MMAR_3814|M.marinum_M FVFGVLGVLLYVVSGVSIFRLVR------YLAREYLLIFATSSS--EAVL
MAV_3974|M.avium_104 RGIGTIGVVLAAFAGGNALAVVPSGYLSDRMGRRTLLIVGLVTSGAATVW
:*.:*.:: .: . : : :.*. ***.. :* .
MSMEG_5302|M.smegmatis_MC2_155 PRLIAKMEHLGVDRSTVGVVVPTGYSFNLDGTAIYLTMASLFIAGALGDP
Mvan_4696|M.vanbaalenii_PYR-1 PRLIAKMEHLGVDRSTVGVVVPTGYSFNLDGTAIYLTMASLFIAGALGDP
MAB_1540|M.abscessus_ATCC_1997 PRLIAKMAHLGVDKSTVGIVVPTGYSFNLDGTAIYLTMASLFVADAMGAP
Mflv_1323|M.gilvum_PYR-GCK PRLIAKMEHAGVKPATVGIVVPTGYSFNLDGTAIYLTMASLFIADALGDP
Mb2470|M.bovis_AF2122/97 PRLITKMKHLGVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHR
Rv2443|M.tuberculosis_H37Rv PRLITKMKHLGVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHR
MMAR_3814|M.marinum_M PRLVAKMKHLGVEPATVGVVVPVGYSFNLDGTALYLTMASLFIADALGRP
MAV_3974|M.avium_104 LGFVASLPVFLVAAGVVGVVT-----------GIYMSPLQAAVADILGNE
:::.: * ..**:*. .:*:: . :*. :*
MSMEG_5302|M.smegmatis_MC2_155 LSVTEQIGLLVFMIVASKGAAGVTGAGLATLAGGLQAHRPDLLDGVGLIV
Mvan_4696|M.vanbaalenii_PYR-1 LSLGEQIGLLVFMIVASKGAAGVTGAGLATLAGGLQAHRPDLLDGVGLIV
MAB_1540|M.abscessus_ATCC_1997 LSVGEQISLLAFMMIASKGAAGVTGAGMATLAAGLQSHRPDLVDGVGMIV
Mflv_1323|M.gilvum_PYR-GCK LSIPEQLGLLAFMIIASKGAAGVSGAGLATLAAGLQSHRPELLDGVGIIV
Mb2470|M.bovis_AF2122/97 LTWGEQIALLAFMIIASKGAAGVSGAGLATLAGGLQAHRPELLDGVGLIV
Rv2443|M.tuberculosis_H37Rv LTWGEQIALLAFMIIASKGAAGVSGAGLATLAGGLQAHRPELLDGVGLIV
MMAR_3814|M.marinum_M LAWGEQISLLVFMIFASKGAAGVSGAGLAALASGLQAYRPELLGGVALVA
MAV_3974|M.avium_104 ARAGLPVATVQMMSDLG-AIVGSMAVGWAAEQIGYGWG--FFISGVVLLI
:. : :* . . .* ..* *: * ::.** ::
MSMEG_5302|M.smegmatis_MC2_155 GIDRFMSEARAVTNFSGNAVATILVGSWTHTIDKDKVDAVLGGDDPFDEL
Mvan_4696|M.vanbaalenii_PYR-1 GIDRFMSEARALTNFSGNAVATLLVGSWTRTIDRDKVNSVLAGDDPFDEL
MAB_1540|M.abscessus_ATCC_1997 GIDRFMSEARALTNFSGNAVATLLIATWTKTMDRDRVKTVLSGADPFDET
Mflv_1323|M.gilvum_PYR-GCK GIDRFMSEARALTNFSGNAVATVLVGSWTDSVDKNRLNEVLDGDRPFDEA
Mb2470|M.bovis_AF2122/97 GIDRFMSEARSLTNFSGNAVATILVASWTKTIDLSKADEVLRGRDPFDES
Rv2443|M.tuberculosis_H37Rv GIDRFMSEARSLTNFSGNAVATILVASWTKTIDLSKADEVLRGRDPFDES
MMAR_3814|M.marinum_M GTDTFMKEARSLTNFSGNAVATILVGWWTKTIDRAKVDAVLHGRDPFDEW
MAV_3974|M.avium_104 AAVGWVMAPETRT--ATELEADLMAASRTSSRCEQQL-------------
. :: ..: * : : * :: . * : :
MSMEG_5302|M.smegmatis_MC2_155 TMVD-DHQTAAPEKEP---------------------AATPA--------
Mvan_4696|M.vanbaalenii_PYR-1 TMLDSDHGSRAQEPAQ---------------------EKIPAPV------
MAB_1540|M.abscessus_ATCC_1997 TMLDDHAGEAVVDKVV---------------------S------------
Mflv_1323|M.gilvum_PYR-GCK TMLDDDDAEDRTTIDR---------------------TARSGAPTAG---
Mb2470|M.bovis_AF2122/97 TMVDPHDEEPPAATPHGGGVPTNPALCDFEQVSLGGLVGRPAGPQRADVD
Rv2443|M.tuberculosis_H37Rv TMVDPHDEEPPAATPHGGGVPTNPALCDFEQVSLGGLVGRPAGPQRADVD
MMAR_3814|M.marinum_M TMIDRDDAPPTGVAES----------------------------------
MAV_3974|M.avium_104 --------------------------------------------------
MSMEG_5302|M.smegmatis_MC2_155 -
Mvan_4696|M.vanbaalenii_PYR-1 -
MAB_1540|M.abscessus_ATCC_1997 -
Mflv_1323|M.gilvum_PYR-GCK -
Mb2470|M.bovis_AF2122/97 G
Rv2443|M.tuberculosis_H37Rv G
MMAR_3814|M.marinum_M -
MAV_3974|M.avium_104 -