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M. vanbaalenii PYR-1 Mvan_4696 (-)

annotation: sodium:dicarboxylate symporter
coordinates: 5035410 - 5036795
length: 461

TTRMDSPTPPEAPRRKRDRTHWLYIAVIVAVVAGVAVGILAPEVGKSVGVLGTMFVALIKMMIAPVIFCT
IVLGIGSVRKAATVGKVGGLAFLYFLVMSTFALAIGLVVGNLLHPGSGLQVSDTAAGKGAELADKAHEAG
GLLDFVQGIIPTTMFSSLTEGSVLQALFIALLVGFALQGLGTAGEPILRGIEHLQKLVFKVLVMILWLAP
IGAFGAIANVVGQTGWAAVGQLMALMLGFYLTCAIFVFGVLGALLRVVSGVSIFKLVRYLAREYLLIVST
SSSESALPRLIAKMEHLGVDRSTVGVVVPTGYSFNLDGTAIYLTMASLFIAGALGDPLSLGEQIGLLVFM
IVASKGAAGVTGAGLATLAGGLQAHRPDLLDGVGLIVGIDRFMSEARALTNFSGNAVATLLVGSWTRTID
RDKVNSVLAGDDPFDELTMLDSDHGSRAQEPAQEKIPAPV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_4696--100% (461)sodium:dicarboxylate symporter

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2470dctA1e-17872.75% (444) C4-dicarboxylate-transport transmembrane protein DctA
M. gilvum PYR-GCKMflv_1323-0.073.80% (439) sodium:dicarboxylate symporter
M. tuberculosis H37RvRv2443dctA1e-17872.75% (444) C4-dicarboxylate-transport transmembrane protein DctA
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1540-0.075.06% (449) sodium:dicarboxylate symporter
M. marinum MMMAR_3814dctA1e-17269.06% (446) C4-dicarboxylate-transport transmembrane protein DctA
M. avium 104-----
M. smegmatis MC2 155MSMEG_5302-0.085.19% (459) aerobic C4-dicarboxylate transport protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_4696|M.vanbaalenii_PYR-1       --MTTRMDSPTPPEAPRRKRDRTHWLYIAVIVAVVAGVAVGILAPEVGKS
MSMEG_5302|M.smegmatis_MC2_155      --MSTTLDRQPEPAPPRR-RDRTHWLYIAVIVAVVAGVAVGLLAPEVGKS
Mflv_1323|M.gilvum_PYR-GCK          -MAATDDDAGTDTTKKTGKRDRTHWLYILVIVAVVAGIVVGLVAPETAAS
MAB_1540|M.abscessus_ATCC_1997      -MTATEPATSESTPPKK-HKDRTHWLYIAVVVAVALGVAVGMLWPGFGRS
Mb2470|M.bovis_AF2122/97            MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGKS
Rv2443|M.tuberculosis_H37Rv         MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGKS
MMAR_3814|M.marinum_M               MTTPLDQPPATDPRASKKRPDRTRWLYFAVIGAVILGVIAGLAVPSIGPH
                                       .                ***:***: *: **  *: .*:  *  .  

Mvan_4696|M.vanbaalenii_PYR-1       VGVLGTMFVALIKMMIAPVIFCTIVLGIGSVRKAATVGKVGGLAFLYFLV
MSMEG_5302|M.smegmatis_MC2_155      VGVLGTMFVNLIKMMIGPVIFCTIVLGIGSVRKAATVGKVGGLAFTYFLV
Mflv_1323|M.gilvum_PYR-GCK          LGVLGELFVKLIKMMTVPVIFCTVVLGIGKVRAAASVGKVGGLAIGYFLV
MAB_1540|M.abscessus_ATCC_1997      VGVLGEIFVSLIKMMISPVIFCTIVLGIGSVRKAASVGRVGGLAFVYFLA
Mb2470|M.bovis_AF2122/97            LTVLGTVFVNLIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYFLT
Rv2443|M.tuberculosis_H37Rv         LTVLGTVFVNLIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYFLT
MMAR_3814|M.marinum_M               VAVLGTTFVNLITMMVAPVIFCTIVLGIGSLNRAALLGKVGGLAFLYFLV
                                    : ***  ** **.**  ******:*****.:. ** :*:*****: ***.

Mvan_4696|M.vanbaalenii_PYR-1       MSTFALAIGLVVGNLLHPGSGLQVSDTAAGKGAELADKAHEAGGLLDFVQ
MSMEG_5302|M.smegmatis_MC2_155      MSTFALAIGLVVGNVLHPGTGMHLTESAAGKGAELAETAHEAGGLMDFVQ
Mflv_1323|M.gilvum_PYR-GCK          MSTIALAIGLVVGNLISPGTGLNVP-HDPGKGAELAGEAESAGGTMAFIS
MAB_1540|M.abscessus_ATCC_1997      MSTVALAIGLVVGNLLAPGTGLHLSGSNQGAGAKYVDQAHAAGGTWHFIK
Mb2470|M.bovis_AF2122/97            MSSVALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAAESHGIAGFIQ
Rv2443|M.tuberculosis_H37Rv         MSSVALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAAESHGIAGFIQ
MMAR_3814|M.marinum_M               MSTAALGIGLFVGNLIGTVRGLHLSVESMGSGVEVADAAPPSGWMHGLLD
                                    **: **.***.***:: .  .:::     * *.  .  *  :     ::.

Mvan_4696|M.vanbaalenii_PYR-1       GIIPTTMFSSLTEGSVLQALFIALLVGFALQGLGTAGEPILRGIEHLQKL
MSMEG_5302|M.smegmatis_MC2_155      GIIPETLFSALTAGSVLQALFVALLVGFALQAMGSAGEPVLRGIVHLQKL
Mflv_1323|M.gilvum_PYR-GCK          DIIPSTLFSAVTEGNVLQALFVALLVGFGIQGIGAHGESLLRGIEALQKL
MAB_1540|M.abscessus_ATCC_1997      SIVPETMFSALTSGSVLQTLFIALLVGFAVQALGGTGESIVRGVGMLQKL
Mb2470|M.bovis_AF2122/97            QIIPRSLPSALTEGNVLQVLLVALLVGFAVQGLGPAGESILRAVENLQKL
Rv2443|M.tuberculosis_H37Rv         QIIPRSLPSALTEGNVLQVLLVALLVGFAVQGLGPAGESILRAVENLQKL
MMAR_3814|M.marinum_M               QVIPTSLLSGLTNGNVLQALFVALLVGFAVQGMGAAGEPILRSVEYLQKL
                                     ::* :: *.:* *.***.*::******.:*.:*  **.::*.:  ****

Mvan_4696|M.vanbaalenii_PYR-1       VFKVLVMILWLAPIGAFGAIANVVGQTGWAAVGQLMALMLGFYLTCAIFV
MSMEG_5302|M.smegmatis_MC2_155      VFKVLAMILWLAPIGAFGAIANVVGQTGWTAVTQLLALMFGFYVTCFVFV
Mflv_1323|M.gilvum_PYR-GCK          VFRILIGVLWLAPIGAFGAIAEVVGDTGFDAVIQLGVLMAAFYITCVIFI
MAB_1540|M.abscessus_ATCC_1997      VFKVLIMVLWLAPIGAFGAIANVVGQTGWDAVKELGTLMLGFYVTCAIFI
Mb2470|M.bovis_AF2122/97            VFKVLVMVLWLAPIGAFGAIANIVATTGFNAVTNLLLLMAGFYLTCVVFV
Rv2443|M.tuberculosis_H37Rv         VFKVLVMVLWLAPIGAFGAIANIVATTGFNAVTNLLLLMAGFYLTCVVFV
MMAR_3814|M.marinum_M               VFKVLGMLLWLAPIGAFGWIASIIGATGWGAVANLLILLVGFYLTCAVFV
                                    **::*  :********** **.::. **: ** :*  *: .**:** :*:

Mvan_4696|M.vanbaalenii_PYR-1       FGVLGALLRVVSGVSIFKLVRYLAREYLLIVSTSSSESALPRLIAKMEHL
MSMEG_5302|M.smegmatis_MC2_155      FGVLGVLMRAVAGVSIFKLVRYLAREYLLIVSTSSSESALPRLIAKMEHL
Mflv_1323|M.gilvum_PYR-GCK          FGVLGALLWAVARVSIFKLARYLAREYLLIVATSSSESALPRLIAKMEHA
MAB_1540|M.abscessus_ATCC_1997      FGVLGTLLWAVSRVSIFRLVRYLAREYLLIVSTSSSESALPRLIAKMAHL
Mb2470|M.bovis_AF2122/97            FGVLGVLLRIVSGLSIFRLLRYLAREYLLIFATSSSEVVLPRLITKMKHL
Rv2443|M.tuberculosis_H37Rv         FGVLGVLLRIVSGLSIFRLLRYLAREYLLIFATSSSEVVLPRLITKMKHL
MMAR_3814|M.marinum_M               FGVLGVLLYVVSGVSIFRLVRYLAREYLLIFATSSSEAVLPRLVAKMKHL
                                    *****.*:  *: :***:* **********.:***** .****::** * 

Mvan_4696|M.vanbaalenii_PYR-1       GVDRSTVGVVVPTGYSFNLDGTAIYLTMASLFIAGALGDPLSLGEQIGLL
MSMEG_5302|M.smegmatis_MC2_155      GVDRSTVGVVVPTGYSFNLDGTAIYLTMASLFIAGALGDPLSVTEQIGLL
Mflv_1323|M.gilvum_PYR-GCK          GVKPATVGIVVPTGYSFNLDGTAIYLTMASLFIADALGDPLSIPEQLGLL
MAB_1540|M.abscessus_ATCC_1997      GVDKSTVGIVVPTGYSFNLDGTAIYLTMASLFVADAMGAPLSVGEQISLL
Mb2470|M.bovis_AF2122/97            GVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHRLTWGEQIALL
Rv2443|M.tuberculosis_H37Rv         GVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHRLTWGEQIALL
MMAR_3814|M.marinum_M               GVEPATVGVVVPVGYSFNLDGTALYLTMASLFIADALGRPLAWGEQISLL
                                    **. :***:***.**********:********:*.*:*  *:  **:.**

Mvan_4696|M.vanbaalenii_PYR-1       VFMIVASKGAAGVTGAGLATLAGGLQAHRPDLLDGVGLIVGIDRFMSEAR
MSMEG_5302|M.smegmatis_MC2_155      VFMIVASKGAAGVTGAGLATLAGGLQAHRPDLLDGVGLIVGIDRFMSEAR
Mflv_1323|M.gilvum_PYR-GCK          AFMIIASKGAAGVSGAGLATLAAGLQSHRPELLDGVGIIVGIDRFMSEAR
MAB_1540|M.abscessus_ATCC_1997      AFMMIASKGAAGVTGAGMATLAAGLQSHRPDLVDGVGMIVGIDRFMSEAR
Mb2470|M.bovis_AF2122/97            AFMIIASKGAAGVSGAGLATLAGGLQAHRPELLDGVGLIVGIDRFMSEAR
Rv2443|M.tuberculosis_H37Rv         AFMIIASKGAAGVSGAGLATLAGGLQAHRPELLDGVGLIVGIDRFMSEAR
MMAR_3814|M.marinum_M               VFMIFASKGAAGVSGAGLAALASGLQAYRPELLGGVALVAGTDTFMKEAR
                                    .**:.********:***:*:**.***::**:*:.**.::.* * **.***

Mvan_4696|M.vanbaalenii_PYR-1       ALTNFSGNAVATLLVGSWTRTIDRDKVNSVLAGDDPFDELTMLDSDHGSR
MSMEG_5302|M.smegmatis_MC2_155      AVTNFSGNAVATILVGSWTHTIDKDKVDAVLGGDDPFDELTMVD-DHQTA
Mflv_1323|M.gilvum_PYR-GCK          ALTNFSGNAVATVLVGSWTDSVDKNRLNEVLDGDRPFDEATMLDDDDAED
MAB_1540|M.abscessus_ATCC_1997      ALTNFSGNAVATLLIATWTKTMDRDRVKTVLSGADPFDETTMLDDHAGEA
Mb2470|M.bovis_AF2122/97            SLTNFSGNAVATILVASWTKTIDLSKADEVLRGRDPFDESTMVDPHDEEP
Rv2443|M.tuberculosis_H37Rv         SLTNFSGNAVATILVASWTKTIDLSKADEVLRGRDPFDESTMVDPHDEEP
MMAR_3814|M.marinum_M               SLTNFSGNAVATILVGWWTKTIDRAKVDAVLHGRDPFDEWTMID-RDDAP
                                    ::**********:*:. ** ::*  : . ** *  **** **:*      

Mvan_4696|M.vanbaalenii_PYR-1       AQEPAQEKIPAPV----------------------------
MSMEG_5302|M.smegmatis_MC2_155      APEKEPAATPA------------------------------
Mflv_1323|M.gilvum_PYR-GCK          RTTIDRTARSGAPTAG-------------------------
MAB_1540|M.abscessus_ATCC_1997      --VVDKVVS--------------------------------
Mb2470|M.bovis_AF2122/97            PAATPHGGGVPTNPALCDFEQVSLGGLVGRPAGPQRADVDG
Rv2443|M.tuberculosis_H37Rv         PAATPHGGGVPTNPALCDFEQVSLGGLVGRPAGPQRADVDG
MMAR_3814|M.marinum_M               PTGVAES----------------------------------