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MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGKSLTVLGTVFVNLIKMMIAPVI FCTIVLGIGSVRKAAAVGKVGGLALAYFLTMSSVALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAA ESHGIAGFIQQIIPRSLPSALTEGNVLQVLLVALLVGFAVQGLGPAGESILRAVENLQKLVFKVLVMVLW LAPIGAFGAIANIVATTGFNAVTNLLLLMAGFYLTCVVFVFGVLGVLLRIVSGLSIFRLLRYLAREYLLI FATSSSEVVLPRLITKMKHLGVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHRLTWGEQIALL AFMIIASKGAAGVSGAGLATLAGGLQAHRPELLDGVGLIVGIDRFMSEARSLTNFSGNAVATILVASWTK TIDLSKADEVLRGRDPFDESTMVDPHDEEPPAATPHGGGVPTNPALCDFEQVSLGGLVGRPAGPQRADVD G
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2443 | dctA | - | 100% (491) | PROBABLE C4-DICARBOXYLATE-TRANSPORT TRANSMEMBRANE PROTEIN DCTA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2470 | dctA | 0.0 | 100.00% (491) | C4-dicarboxylate-transport transmembrane protein DctA |
| M. gilvum PYR-GCK | Mflv_1323 | - | 1e-169 | 69.25% (439) | sodium:dicarboxylate symporter |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1540 | - | 1e-169 | 70.14% (432) | sodium:dicarboxylate symporter |
| M. marinum M | MMAR_3814 | dctA | 1e-177 | 71.62% (451) | C4-dicarboxylate-transport transmembrane protein DctA |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5302 | - | 0.0 | 72.55% (459) | aerobic C4-dicarboxylate transport protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4696 | - | 1e-178 | 72.75% (444) | sodium:dicarboxylate symporter |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5302|M.smegmatis_MC2_155 --MSTTLDRQPEPAPPRR-RDRTHWLYIAVIVAVVAGVAVGLLAPEVGKS
Mvan_4696|M.vanbaalenii_PYR-1 --MTTRMDSPTPPEAPRRKRDRTHWLYIAVIVAVVAGVAVGILAPEVGKS
Mflv_1323|M.gilvum_PYR-GCK -MAATDDDAGTDTTKKTGKRDRTHWLYILVIVAVVAGIVVGLVAPETAAS
MAB_1540|M.abscessus_ATCC_1997 -MTATEPATSESTPPKK-HKDRTHWLYIAVVVAVALGVAVGMLWPGFGRS
Rv2443|M.tuberculosis_H37Rv MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGKS
Mb2470|M.bovis_AF2122/97 MTAPLDRAPVTDLPANNKGRDRTHWLYLAVIFAVIAGVIVGLTAPSTGKS
MMAR_3814|M.marinum_M MTTPLDQPPATDPRASKKRPDRTRWLYFAVIGAVILGVIAGLAVPSIGPH
. ***:***: *: ** *: .*: * .
MSMEG_5302|M.smegmatis_MC2_155 VGVLGTMFVNLIKMMIGPVIFCTIVLGIGSVRKAATVGKVGGLAFTYFLV
Mvan_4696|M.vanbaalenii_PYR-1 VGVLGTMFVALIKMMIAPVIFCTIVLGIGSVRKAATVGKVGGLAFLYFLV
Mflv_1323|M.gilvum_PYR-GCK LGVLGELFVKLIKMMTVPVIFCTVVLGIGKVRAAASVGKVGGLAIGYFLV
MAB_1540|M.abscessus_ATCC_1997 VGVLGEIFVSLIKMMISPVIFCTIVLGIGSVRKAASVGRVGGLAFVYFLA
Rv2443|M.tuberculosis_H37Rv LTVLGTVFVNLIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYFLT
Mb2470|M.bovis_AF2122/97 LTVLGTVFVNLIKMMIAPVIFCTIVLGIGSVRKAAAVGKVGGLALAYFLT
MMAR_3814|M.marinum_M VAVLGTTFVNLITMMVAPVIFCTIVLGIGSLNRAALLGKVGGLAFLYFLV
: *** ** **.** ******:*****.:. ** :*:*****: ***.
MSMEG_5302|M.smegmatis_MC2_155 MSTFALAIGLVVGNVLHPGTGMHLTESAAGKGAELAETAHEAGGLMDFVQ
Mvan_4696|M.vanbaalenii_PYR-1 MSTFALAIGLVVGNLLHPGSGLQVSDTAAGKGAELADKAHEAGGLLDFVQ
Mflv_1323|M.gilvum_PYR-GCK MSTIALAIGLVVGNLISPGTGLNVP-HDPGKGAELAGEAESAGGTMAFIS
MAB_1540|M.abscessus_ATCC_1997 MSTVALAIGLVVGNLLAPGTGLHLSGSNQGAGAKYVDQAHAAGGTWHFIK
Rv2443|M.tuberculosis_H37Rv MSSVALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAAESHGIAGFIQ
Mb2470|M.bovis_AF2122/97 MSSVALGIGLIVGNLLSPGRDLHLRPGAVGSGAALAGQAAESHGIAGFIQ
MMAR_3814|M.marinum_M MSTAALGIGLFVGNLIGTVRGLHLSVESMGSGVEVADAAPPSGWMHGLLD
**: **.***.***:: . .::: * *. . * : ::.
MSMEG_5302|M.smegmatis_MC2_155 GIIPETLFSALTAGSVLQALFVALLVGFALQAMGSAGEPVLRGIVHLQKL
Mvan_4696|M.vanbaalenii_PYR-1 GIIPTTMFSSLTEGSVLQALFIALLVGFALQGLGTAGEPILRGIEHLQKL
Mflv_1323|M.gilvum_PYR-GCK DIIPSTLFSAVTEGNVLQALFVALLVGFGIQGIGAHGESLLRGIEALQKL
MAB_1540|M.abscessus_ATCC_1997 SIVPETMFSALTSGSVLQTLFIALLVGFAVQALGGTGESIVRGVGMLQKL
Rv2443|M.tuberculosis_H37Rv QIIPRSLPSALTEGNVLQVLLVALLVGFAVQGLGPAGESILRAVENLQKL
Mb2470|M.bovis_AF2122/97 QIIPRSLPSALTEGNVLQVLLVALLVGFAVQGLGPAGESILRAVENLQKL
MMAR_3814|M.marinum_M QVIPTSLLSGLTNGNVLQALFVALLVGFAVQGMGAAGEPILRSVEYLQKL
::* :: *.:* *.***.*::******.:*.:* **.::*.: ****
MSMEG_5302|M.smegmatis_MC2_155 VFKVLAMILWLAPIGAFGAIANVVGQTGWTAVTQLLALMFGFYVTCFVFV
Mvan_4696|M.vanbaalenii_PYR-1 VFKVLVMILWLAPIGAFGAIANVVGQTGWAAVGQLMALMLGFYLTCAIFV
Mflv_1323|M.gilvum_PYR-GCK VFRILIGVLWLAPIGAFGAIAEVVGDTGFDAVIQLGVLMAAFYITCVIFI
MAB_1540|M.abscessus_ATCC_1997 VFKVLIMVLWLAPIGAFGAIANVVGQTGWDAVKELGTLMLGFYVTCAIFI
Rv2443|M.tuberculosis_H37Rv VFKVLVMVLWLAPIGAFGAIANIVATTGFNAVTNLLLLMAGFYLTCVVFV
Mb2470|M.bovis_AF2122/97 VFKVLVMVLWLAPIGAFGAIANIVATTGFNAVTNLLLLMAGFYLTCVVFV
MMAR_3814|M.marinum_M VFKVLGMLLWLAPIGAFGWIASIIGATGWGAVANLLILLVGFYLTCAVFV
**::* :********** **.::. **: ** :* *: .**:** :*:
MSMEG_5302|M.smegmatis_MC2_155 FGVLGVLMRAVAGVSIFKLVRYLAREYLLIVSTSSSESALPRLIAKMEHL
Mvan_4696|M.vanbaalenii_PYR-1 FGVLGALLRVVSGVSIFKLVRYLAREYLLIVSTSSSESALPRLIAKMEHL
Mflv_1323|M.gilvum_PYR-GCK FGVLGALLWAVARVSIFKLARYLAREYLLIVATSSSESALPRLIAKMEHA
MAB_1540|M.abscessus_ATCC_1997 FGVLGTLLWAVSRVSIFRLVRYLAREYLLIVSTSSSESALPRLIAKMAHL
Rv2443|M.tuberculosis_H37Rv FGVLGVLLRIVSGLSIFRLLRYLAREYLLIFATSSSEVVLPRLITKMKHL
Mb2470|M.bovis_AF2122/97 FGVLGVLLRIVSGLSIFRLLRYLAREYLLIFATSSSEVVLPRLITKMKHL
MMAR_3814|M.marinum_M FGVLGVLLYVVSGVSIFRLVRYLAREYLLIFATSSSEAVLPRLVAKMKHL
*****.*: *: :***:* **********.:***** .****::** *
MSMEG_5302|M.smegmatis_MC2_155 GVDRSTVGVVVPTGYSFNLDGTAIYLTMASLFIAGALGDPLSVTEQIGLL
Mvan_4696|M.vanbaalenii_PYR-1 GVDRSTVGVVVPTGYSFNLDGTAIYLTMASLFIAGALGDPLSLGEQIGLL
Mflv_1323|M.gilvum_PYR-GCK GVKPATVGIVVPTGYSFNLDGTAIYLTMASLFIADALGDPLSIPEQLGLL
MAB_1540|M.abscessus_ATCC_1997 GVDKSTVGIVVPTGYSFNLDGTAIYLTMASLFVADAMGAPLSVGEQISLL
Rv2443|M.tuberculosis_H37Rv GVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHRLTWGEQIALL
Mb2470|M.bovis_AF2122/97 GVQSSTVGVVVPTGYSFNLDGTAIYLTMASLFIADAMGHRLTWGEQIALL
MMAR_3814|M.marinum_M GVEPATVGVVVPVGYSFNLDGTALYLTMASLFIADALGRPLAWGEQISLL
**. :***:***.**********:********:*.*:* *: **:.**
MSMEG_5302|M.smegmatis_MC2_155 VFMIVASKGAAGVTGAGLATLAGGLQAHRPDLLDGVGLIVGIDRFMSEAR
Mvan_4696|M.vanbaalenii_PYR-1 VFMIVASKGAAGVTGAGLATLAGGLQAHRPDLLDGVGLIVGIDRFMSEAR
Mflv_1323|M.gilvum_PYR-GCK AFMIIASKGAAGVSGAGLATLAAGLQSHRPELLDGVGIIVGIDRFMSEAR
MAB_1540|M.abscessus_ATCC_1997 AFMMIASKGAAGVTGAGMATLAAGLQSHRPDLVDGVGMIVGIDRFMSEAR
Rv2443|M.tuberculosis_H37Rv AFMIIASKGAAGVSGAGLATLAGGLQAHRPELLDGVGLIVGIDRFMSEAR
Mb2470|M.bovis_AF2122/97 AFMIIASKGAAGVSGAGLATLAGGLQAHRPELLDGVGLIVGIDRFMSEAR
MMAR_3814|M.marinum_M VFMIFASKGAAGVSGAGLAALASGLQAYRPELLGGVALVAGTDTFMKEAR
.**:.********:***:*:**.***::**:*:.**.::.* * **.***
MSMEG_5302|M.smegmatis_MC2_155 AVTNFSGNAVATILVGSWTHTIDKDKVDAVLGGDDPFDELTMVD-DHQTA
Mvan_4696|M.vanbaalenii_PYR-1 ALTNFSGNAVATLLVGSWTRTIDRDKVNSVLAGDDPFDELTMLDSDHGSR
Mflv_1323|M.gilvum_PYR-GCK ALTNFSGNAVATVLVGSWTDSVDKNRLNEVLDGDRPFDEATMLDDDDAED
MAB_1540|M.abscessus_ATCC_1997 ALTNFSGNAVATLLIATWTKTMDRDRVKTVLSGADPFDETTMLDDHAGEA
Rv2443|M.tuberculosis_H37Rv SLTNFSGNAVATILVASWTKTIDLSKADEVLRGRDPFDESTMVDPHDEEP
Mb2470|M.bovis_AF2122/97 SLTNFSGNAVATILVASWTKTIDLSKADEVLRGRDPFDESTMVDPHDEEP
MMAR_3814|M.marinum_M SLTNFSGNAVATILVGWWTKTIDRAKVDAVLHGRDPFDEWTMID-RDDAP
::**********:*:. ** ::* : . ** * **** **:*
MSMEG_5302|M.smegmatis_MC2_155 APEKEPAATPA------------------------------
Mvan_4696|M.vanbaalenii_PYR-1 AQEPAQEKIPAPV----------------------------
Mflv_1323|M.gilvum_PYR-GCK RTTIDRTARSGAPTAG-------------------------
MAB_1540|M.abscessus_ATCC_1997 --VVDKVVS--------------------------------
Rv2443|M.tuberculosis_H37Rv PAATPHGGGVPTNPALCDFEQVSLGGLVGRPAGPQRADVDG
Mb2470|M.bovis_AF2122/97 PAATPHGGGVPTNPALCDFEQVSLGGLVGRPAGPQRADVDG
MMAR_3814|M.marinum_M PTGVAES----------------------------------