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ELRHLTYFLAVAEELNFARAAENLRIAPSPLSRAIRELEKELRAPLFDRGTRHVALTTAGVALVPKAQEI LSQVAALRQVTSHSARTRAELTMGVRAVPDTLRRTLIDDVFHAVDAEATVEIVARRTEDQYRALLRGEFD FGVTVGLPDDPRIDYLEMMTETYGIAVPDIEPYRSMEIVRPEDISALTMIRHDQEHVLDGFEPYYRSAAQ STSVTNDIVGEMHALVAAGRHCCFAVLNPDAPWTRLVSGDGVVIRKLTAQPYVTTCLTWLARRSGEDDLG AYIARATERFAEPLRL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4394 | - | - | 100% (297) | LysR family protein transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3840 | - | 2e-20 | 35.20% (196) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5712 | - | 1e-17 | 53.01% (83) | LysR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0121 | oxyS | 3e-14 | 29.66% (236) | oxidative stress response regulatory protein OXYS |
| M. gilvum PYR-GCK | Mflv_2332 | - | 2e-18 | 30.39% (204) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0117 | oxyS | 3e-14 | 29.66% (236) | oxidative stress response regulatory protein OXYS |
| M. leprae Br4923 | MLBr_02663 | oxyS | 8e-16 | 29.14% (302) | putative LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3208c | - | 7e-16 | 31.47% (197) | LysR family transcriptional regulator |
| M. marinum M | MMAR_2756 | oxyR | 8e-12 | 28.86% (201) | hydrogen peroxide-inducible genes activator, OxyR |
| M. avium 104 | MAV_5191 | - | 4e-14 | 33.14% (169) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_3504 | - | 9e-12 | 42.22% (90) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 6e-12 | 28.86% (201) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_4315 | - | 5e-19 | 30.88% (204) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0121|M.bovis_AF2122/97 ---------------MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSA
Rv0117|M.tuberculosis_H37Rv ---------------MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSA
MLBr_02663|M.leprae_Br4923 ---------------MLFRQLEYFVAVAQERHFARAAERCYVSQPALSSA
MAV_5191|M.avium_104 ---------------MLFRQLEYFVAVASERHFARAAEKCFVSQPALSAA
MMAR_2756|M.marinum_M MLATILIGMTDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MUL_2998|M.ulcerans_Agy99 -----MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
Mflv_2332|M.gilvum_PYR-GCK -------------MDIDFTRLRYFVAVADELHFKRAADKLRITPPPLSKQ
Mvan_4315|M.vanbaalenii_PYR-1 -------------MDIDFTRLRYFVAVADELHFKRAADKLMITPPPLSKQ
MAB_3208c|M.abscessus_ATCC_199 ---------------MELRQLEYFLAVAEHANFTRAAEALHVAQPWVSAQ
TH_3504|M.thermoresistible__bu ----------VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSA
MSMEG_4394|M.smegmatis_MC2_155 ---------------MELRHLTYFLAVAEELNFARAAENLRIAPSPLSRA
: * *:***. * ** :: :*
Mb0121|M.bovis_AF2122/97 IAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVDAV
Rv0117|M.tuberculosis_H37Rv IAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVDAV
MLBr_02663|M.leprae_Br4923 IAKLERELNVTLINRGHSFEGLTPEGERLVVWAKRILAEHDAFKAEVHAV
MAV_5191|M.avium_104 IAKLEKELNVTLINRGHSFEGLTPEGERLVVWARRILAEHDAFKAEVDAV
MMAR_2756|M.marinum_M LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MUL_2998|M.ulcerans_Agy99 LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
Mflv_2332|M.gilvum_PYR-GCK IKLLEKELGGPLFERGYHEVRLSPLGERLVGPAREILRQVEDFKAAATQG
Mvan_4315|M.vanbaalenii_PYR-1 IKLLEKELGGPLFERGYHDVRLTPLGQRLVGPAREILRQVEEFKAVATQA
MAB_3208c|M.abscessus_ATCC_199 VRRLERELGNELFDRSSRVLRLTEFGKALLPLAGAALRTVGEIRSAADAM
TH_3504|M.thermoresistible__bu VRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQT
MSMEG_4394|M.smegmatis_MC2_155 IRELEKELRAPLFDRGTRHVALTTAGVALVPKAQEILSQVAALR-QVTSH
: ** : *. *. *: * *: . : . .
Mb0121|M.bovis_AF2122/97 RSGITGTLRLGTVPTAS-TTASLVLSAFCSAHPLAKVQVCSRLAATELYR
Rv0117|M.tuberculosis_H37Rv RSGITGTLRLGTVPTAS-TTASLVLSAFCSAHPLAKVQVCSRLAATELYR
MLBr_02663|M.leprae_Br4923 RSGITGTLRLGTVPTAS-TTASLVLSAFCSEHPLIKVQICSRLPVTELHR
MAV_5191|M.avium_104 RSGVTGTLRLGTVPTAS-TTASLLLSAFCSAHPLVKVQILSRLSAGELYR
MMAR_2756|M.marinum_M ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVIEDQTERLLT-
MUL_2998|M.ulcerans_Agy99 ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVIEDQTERLLT-
Mflv_2332|M.gilvum_PYR-GCK VRGLA-PLRVSATAYAPSDLLGELEAVLAGLPGPTEFSVPG--SAAEVTA
Mvan_4315|M.vanbaalenii_PYR-1 VRGLA-PVRVSATAYAPSDLLGELEAAIASLPVPTEFSVPG--SAAEVTA
MAB_3208c|M.abscessus_ATCC_199 AGVLCGQLAIGTVPHPS-PLLAEALAAYRRAHPAVTVTLTEARSDQLAT-
TH_3504|M.thermoresistible__bu EAAAQAHYVIGHTPALSGAEAYALIEPAVTAYPSTSFTLRQLYPDALTD-
MSMEG_4394|M.smegmatis_MC2_155 SARTRAELTMGVRAVPDTLRRTLIDDVFHAVDAEATVEIVARRTEDQYR-
.. . . : .
Mb0121|M.bovis_AF2122/97 RLREFELDAVIVHPETQDS-DDVDLVPLYEEQYVLLSPADMLPPGTSTLV
Rv0117|M.tuberculosis_H37Rv RLREFELDAVIVHPETQDS-DDVDLVPLYEEQYVLLSPADMLPPGTSTLV
MLBr_02663|M.leprae_Br4923 RLGDFELDAVIVHSAPDDT-HAVDLVPLYHEHYVLVSPADMLPPGASVLA
MAV_5191|M.avium_104 RLREFELDAAIAHTAPDDI-PDVNLVPVYRERYVLLAPADLLASGAATMT
MMAR_2756|M.marinum_M ALREGSLDTALIA-LPADY-GGLTEIPIYEEDFVLALPPGHPMADRHGVP
MUL_2998|M.ulcerans_Agy99 ALREGSLDTALIA-LPADY-GGLTEIPIYEEDFVLALPPGHPMADRHGVP
Mflv_2332|M.gilvum_PYR-GCK KLIAGQSELGLIHLPATDKRLRHRVVASYQGGVAVRFDDPLAAKDLVSIE
Mvan_4315|M.vanbaalenii_PYR-1 KLIAGQAELGLIHLPANDKRLRYKVVASYQGGIAVRFDDPLAAKDLVSIE
MAB_3208c|M.abscessus_ATCC_199 AVVERRLDMAVMAWLAQPP-SQLRERILAKENIVAVVHRDDPLAGRESVA
TH_3504|M.thermoresistible__bu AVFDGTVQLGLRRGVVPTP--ELATAVIGYHRVRVAFVDSHPLAARESVD
MSMEG_4394|M.smegmatis_MC2_155 ALLRGEFDFGVTVGLPDDP--RIDYLEMMTETYGIAVPDIEPYRSMEIVR
: : : :
Mb0121|M.bovis_AF2122/97 WRDAAQLPLALLTA-DMRDR-QVIDAAFADHAVSAIPQVETDSVASLFAQ
Rv0117|M.tuberculosis_H37Rv WRDAAQLPLALLTA-DMRDR-QVIDAAFADHAVSAIPQVETDSVASLFAQ
MLBr_02663|M.leprae_Br4923 WPEASQLPLALLTP-DMRDR-QLIDRAFAGHAITATPQVETDSVASLFAQ
MAV_5191|M.avium_104 WVQAAQLPLALLTP-DMRDR-QIIDRAFADHGITLHPQVETDSVASLFAQ
MMAR_2756|M.marinum_M VAALSELPLLLLDE-GHCLRDQALDVCQNAGVRAELADTRAASLATAVQC
MUL_2998|M.ulcerans_Agy99 VAALSELPLLLLDE-GHCLRDQALDVCQNAGVRAEHADTRADSLATAVQC
Mflv_2332|M.gilvum_PYR-GCK ELRDREVAIDFARP-NPVVL-AGLTRRLNRKGVHHIVRTTNQRGGEVEMA
Mvan_4315|M.vanbaalenii_PYR-1 ELRDREVAIDVARP-NPVVL-AGLTRGLNRKGVHRIVRTTNQRGGEVEMA
MAB_3208c|M.abscessus_ATCC_199 LAELRDRALISHPQ-GCEIR-TALDQACLATGFTPRVVFETSSADMMRHL
TH_3504|M.thermoresistible__bu ITELAREQVALWAPPGTSYYSDFLMGACRRAGFEPDYVVSRVQGAATVAA
MSMEG_4394|M.smegmatis_MC2_155 PEDISALTMIRHDQ---EHVLDGFEPYYRSAAQSTSVTNDIVGEMHALVA
: :
Mb0121|M.bovis_AF2122/97 VATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNALG
Rv0117|M.tuberculosis_H37Rv VATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNALG
MLBr_02663|M.leprae_Br4923 VATGNWACIVPHTWLWTTPIG----AEIRAVEMVDPVLKADVALATNSAG
MAV_5191|M.avium_104 ASAGSWASIVPHTWLWASPLG----PGIRAVELVDPVLTADVVLAIKSHG
MMAR_2756|M.marinum_M VNGGLGVTLIPQSAVSVEAAR----SRVGLAHFAAPTPGRRIGLVYRASS
MUL_2998|M.ulcerans_Agy99 VNGGLGVTLIPQSAVSVEAAR----SRVGLTHFAAPTPGRRIGLVYRASS
Mflv_2332|M.gilvum_PYR-GCK TQVFNRHLVAVVSYAPESFIG-----KIFSPPEFKLIPVDESTWAPAEIA
Mvan_4315|M.vanbaalenii_PYR-1 TQVFNRHLVAVVSYAPDSFIG-----KIFSPPEFKLIPLDESTWAPAEIA
MAB_3208c|M.abscessus_ATCC_199 VVRDLGVAVTPR--LPREQLG-----RLRQIDLSDRAMSGRLSLLWRGKG
TH_3504|M.thermoresistible__bu PLTTGGIAFVTAAAGPTMNGR------VQVVDLTPPLLVP-VQALWQRHT
MSMEG_4394|M.smegmatis_MC2_155 AGRHCCFAVLNPDAPWTRLVSG--DGVVIRKLTAQPYVTTCLTWLARRSG
. :
Mb0121|M.bovis_AF2122/97 PGSPVARALITCAQALALNEFFDTQLRGITRRR
Rv0117|M.tuberculosis_H37Rv PGSPVARALITCAQALALNEFFDTQLRGITRRR
MLBr_02663|M.leprae_Br4923 PGSPVARALVASAKQLALNEFFEAQLAGITRRR
MAV_5191|M.avium_104 PGSPIARALAASAGRLQLNDFFDAQLLGVTRRR
MMAR_2756|M.marinum_M GRDEAYRQLAAIMGESISNEQQVRLVN------
MUL_2998|M.ulcerans_Agy99 GRDEAYRQLAAIMGESISNEQQVRLVN------
Mflv_2332|M.gilvum_PYR-GCK LAWVPERVQGRLAEVELMVEQIADRLGPVHRGA
Mvan_4315|M.vanbaalenii_PYR-1 LAWVPERVQARLTEVELMVEQIADRLGPVHRGA
MAB_3208c|M.abscessus_ATCC_199 ATLEAVAFAACIDELCRKDANLVS---------
TH_3504|M.thermoresistible__bu LSAIRDRILEGLG--------------------
MSMEG_4394|M.smegmatis_MC2_155 EDDLGAYIARATERFAEPLRL------------