For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
KLQVTQLRLEAAGVISVTLRDPDGHRLPAWAAGAHLPITLPSGRVRQYSLCGALDDPFSYTVAVLLVADG RGGSREIHEQLRIGQILEVGEPKNNFELVEAPRYLFIAGGIGITPILAMMESLRAAGEEVPFRLVYGGRT RASMAFLDRLAGFGEVEVLPQDTHGIPDLATAFAASAPGTRVYCCGPAPMLDAVQSLAAEHPDVFLHTER FSAGVREPAEGAADDSAFEVELARTGVTVTVPEDTSVLDAVLAVAPETPYSCTAGFCGTCETKVLAGEVD HRDDLLTDEERQANTTMMICVSRALGNAKLTLDL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4371 | - | - | 100% (315) | vanillate O-demethylase oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_4152 | - | 4e-68 | 46.06% (317) | phenoxybenzoate dioxygenase beta subunit |
| M. smegmatis MC2 155 | MSMEG_3676 | - | 2e-57 | 41.72% (314) | phenoxybenzoate dioxygenase beta subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2798c | - | 2e-60 | 42.81% (306) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3426 | - | 4e-62 | 45.99% (324) | ferredoxin |
| M. tuberculosis H37Rv | Rv2776c | - | 2e-60 | 42.81% (306) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0088c | - | 8e-66 | 44.41% (322) | putative oxidoreductase |
| M. marinum M | MMAR_1933 | - | 2e-61 | 42.90% (317) | oxidoreductase |
| M. avium 104 | MAV_4119 | - | 1e-62 | 44.27% (314) | oxidoreductase |
| M. thermoresistible (build 8) | TH_3804 | - | 1e-64 | 45.78% (308) | PUTATIVE ferredoxin |
| M. ulcerans Agy99 | MUL_2159 | - | 8e-60 | 42.59% (317) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3180 | - | 7e-64 | 45.96% (322) | ferredoxin |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3426|M.gilvum_PYR-GCK ------------------------MGVLGRLRYDVTIGLADAALHGMFAT
Mvan_3180|M.vanbaalenii_PYR-1 MTRLFSQFRQT------------PPSPSGRLRHDVMLGIAETAIAGMFAA
TH_3804|M.thermoresistible__bu -MRMLARLRAT------------PPSSSGRIRHDLLLGVADATISSLWKV
MAB_0088c|M.abscessus_ATCC_199 ---MFDRFRHTGQPTSKRKRPSLPPTLYGTLPVSPTIALGTALFPVAVRA
MSMEG_4371|M.smegmatis_MC2_155 --------------------------------------------------
Mb2798c|M.bovis_AF2122/97 --------------------------------------------------
Rv2776c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1933|M.marinum_M -MAVSESSWTS-----------RPADLYGRSHRDRFA-TALWGVRTMFGG
MUL_2159|M.ulcerans_Agy99 -MAVSESSWTS-----------RPADLYGRSHRDRFA-TALWGVRTMFGG
MAV_4119|M.avium_104 -MTMAQAIWES-----------IPADLYGRRKRDRMY-TALYGVGALFGG
Mflv_3426|M.gilvum_PYR-GCK SAAMRRIRPPDG--VPETFPLTVTSRRVVARDQDVVELTLS---GDDLPR
Mvan_3180|M.vanbaalenii_PYR-1 SAAVRRVRMPAA--GPDTIPLTVTGRRVVAHDQDVVELTLA---GDRLPR
TH_3804|M.thermoresistible__bu SEVLRTPRLPAV--DAEPITLTVRDRRVVAHDQDVIALTLVAADGGQLPP
MAB_0088c|M.abscessus_ATCC_199 IGALLILKKPPENHVDRTLKLVVKDRWIEAKDQDVASLVLASPDGDRLPP
MSMEG_4371|M.smegmatis_MC2_155 ------------------MKLQVTQLRLEAAG--VISVTLRDPDGHRLPA
Mb2798c|M.bovis_AF2122/97 --------------MRRTNPAVVTKRELVAPD--VVALTLADPGGGLLPA
Rv2776c|M.tuberculosis_H37Rv --------------MRRTNPAVVTKRELVAPD--VVALTLADPGGGLLPA
MMAR_1933|M.marinum_M FARFSRWNPSRVTPVGRTHRARVVERELVAPD--VVALTLADPDGGLLPS
MUL_2159|M.ulcerans_Agy99 FARFSRWNPSRVTPVGRTHRARVVERELVAPD--VVALTLADPDGGLLPS
MAV_4119|M.avium_104 LASASRWTPARVVPVRRTTTAVVTQREELAPD--VVAFTLADPHGGLLPS
* * . * ..* * **
Mflv_3426|M.gilvum_PYR-GCK WHPGAHLDLHLPSGRIRQYSLCGEPTA-GHYRVAVRRIPDGGGGSVEVHD
Mvan_3180|M.vanbaalenii_PYR-1 WFPGAHLDVHLPSGRVRQYSLCGDPDS-AEYRIAVRRIPDGGGGSVEVHD
TH_3804|M.thermoresistible__bu WRPGAHIDVTLPSGRVRQYSLCGDPAVRDRYRIAVRRIPDGGGGSVEVHD
MAB_0088c|M.abscessus_ATCC_199 WHPGAHLDLLLPSGRMRQYSLCGDVSDPYHYRIAVRRIPGGGGGSIEVHD
MSMEG_4371|M.smegmatis_MC2_155 WAAGAHLPITLPSGRVRQYSLCGALDDPFSYTVAVLLVADGRGGSREIHE
Mb2798c|M.bovis_AF2122/97 WSPGGHIDVQLPSGRRRQYSLCGVPGRRTDYRIAIRRIADGGGGSIEMHE
Rv2776c|M.tuberculosis_H37Rv WSPGGHIDVQLPSGRRRQYSLCGVPGRRTDYRIAIRRIADGGGGSIEMHE
MMAR_1933|M.marinum_M WSPGGHIDVQLPSGRRRQYSLCGPPGRRTDYRIAVRRIADGGGGSIEMHA
MUL_2159|M.ulcerans_Agy99 WSPGGHIDVQLPSRRRRQYSLCGPPGRRTDYRIAVRRIADGGGGSIEMHA
MAV_4119|M.avium_104 WTPGAHIDVRLPSGRRRQYSLCGPPGRRTDYRIAVRRIEDGGGGSIEMHD
* .*.*: : *** * ******* * :*: : .* *** *:*
Mflv_3426|M.gilvum_PYR-GCK ALPVGSTVRTHGPRNAFPLAVPGYGSPARRFRFIAGGIGITPILPMLALA
Mvan_3180|M.vanbaalenii_PYR-1 ALEIGSTVHTHGPRNAFPLTVPGYGSPARRFRFIAGGIGITPILPMLGLA
TH_3804|M.thermoresistible__bu ALHLGARVTTHGPRNAFPLSVPGYGSPARRLRFIAGGIGITPILPMLAEA
MAB_0088c|M.abscessus_ATCC_199 ALQIGATVSILGPRNAFPLAMTQPGP--RKLHFVAGGIGITPILSMIAFA
MSMEG_4371|M.smegmatis_MC2_155 QLRIGQILEVGEPKNNFELVEA------PRYLFIAGGIGITPILAMMESL
Mb2798c|M.bovis_AF2122/97 AFDVGDTCEFEGPRNAFHLGLAE-----RDVLFVIGGIGVTPILPMIRAA
Rv2776c|M.tuberculosis_H37Rv AFDVGDTCEFEGPRNAFHLGLAE-----RDVLFVIGGIGVTPILPMIRAA
MMAR_1933|M.marinum_M AYQPGDILVFEGPRNAFYLGAAE-----HDMLFVIGGIGVTPILPMVALA
MUL_2159|M.ulcerans_Agy99 AYQPGDILVFEGPRNAFYLGAAE-----HDMLFVIGGIGVTPILPMVALA
MAV_4119|M.avium_104 TFRVGDALEFEGPRNAFYLVTDE-----RDVLFVIGGIGVTPILPMIQTA
* *:* * * *: ****:****.*:
Mflv_3426|M.gilvum_PYR-GCK RSLG--VDWSMVYTGRSADALPFVDEVAAFGS-PVEIRTDDRRG-LPTAA
Mvan_3180|M.vanbaalenii_PYR-1 RRLG--VDWSMVYTGRSVDSLPFVDEVTAFGA-AVDIRTDDRHG-LPAAA
TH_3804|M.thermoresistible__bu QAFG--VPWSMIYAGRSRDSLPFLEELTRYGD-RVRVRTDDVAG-LPTAA
MAB_0088c|M.abscessus_ATCC_199 EQLG--KPWTMVYTGRHRDSLPFLNELKRFGD-RVIIRTDDQSG-LPTAD
MSMEG_4371|M.smegmatis_MC2_155 RAAGEEVPFRLVYGGRTRASMAFLDRLAGFG--EVEVLPQDTHG-IPDLA
Mb2798c|M.bovis_AF2122/97 EQRG--IDWRAIYAGRGREYMPFLDEVVAVAPGRVTVWADDEHGRFASVD
Rv2776c|M.tuberculosis_H37Rv EQRG--IDWRAIYAGRGREYMPFLDEVVAVAPGRVTVWADDEHGRFASVD
MMAR_1933|M.marinum_M HQRG--VNWRAMYAGRSREYMPLLDELVAMAPERVSVWADDEHGRFAQVE
MUL_2159|M.ulcerans_Agy99 HQRG--VNWRAVYAGRSREYMPLLDELVAMAPEGVSVWADDEHGRFAQVE
MAV_4119|M.avium_104 QQHG--INWRAVYAGRSRDYMPLLDEVVAVAPERVSVWADDERGRIPTAA
. * : :* ** :.:::.: . * : .:* * :.
Mflv_3426|M.gilvum_PYR-GCK ELLGDCPADTSVYACGPAPMLTAVRDALVGRDDVELHFERFAAPP-----
Mvan_3180|M.vanbaalenii_PYR-1 ELLGDCADGTAVYACGPAPMLTAVRAALVGRDDVELHFERFAAPP-----
TH_3804|M.thermoresistible__bu ELLGACPDGTAVYACGPPAMLTAIRAELAGRRNVELHFERFAAPP-----
MAB_0088c|M.abscessus_ATCC_199 DLLPGVGENDAVYCCGPAPMLAVLQRRLLEMPSVELHFERFAAAP-----
MSMEG_4371|M.smegmatis_MC2_155 TAFAASAPGTRVYCCGPAPMLDAVQSLAAEHPDVFLHTERFSAGVREPAE
Mb2798c|M.bovis_AF2122/97 ELLAGAGPTTAVYVCGPPGMLEAVRVARNQHADAPLHYERFSPPP-----
Rv2776c|M.tuberculosis_H37Rv ELLAGAGPTTAVYVCGPPGMLEAVRVARNQHADAPLHYERFSPPP-----
MMAR_1933|M.marinum_M DLVAGAGPKTAVYVCGPPPMLEAVRAARAEYPCAPLHYERFSPPP-----
MUL_2159|M.ulcerans_Agy99 DLVAGAGLKTAVYVCGPPPMLEAVRAARAEYPCAPLHYERFSPPP-----
MAV_4119|M.avium_104 DLLAEAGPATAVYVCGPTAMLEAVRTARDEHADAPLHYERFGPPP-----
. ** ***. ** .:: . ** ***..
Mflv_3426|M.gilvum_PYR-GCK -VVDGRPFR--VAAAGVTVDVGVDETLLAALGRAGVTTPYSCRQGFCGTC
Mvan_3180|M.vanbaalenii_PYR-1 -VTDGRPFQATVASTGQQVDVGADETLLAALRRAGVDASYSCQQGFCGTC
TH_3804|M.thermoresistible__bu -VVDGRPFSVRIASTGAEVPVGADETLLAALGRAGVQAPYSCQQGFCGTC
MAB_0088c|M.abscessus_ATCC_199 -VVDGHPFEVQLGPGGPVLDVPADRTALDVIKKRLPHVAYSCQQGFCGTC
MSMEG_4371|M.smegmatis_MC2_155 GAADDSAFEVELARTGVTVTVPEDTSVLDAVLAVAPETPYSCTAGFCGTC
Mb2798c|M.bovis_AF2122/97 -VVDGVPFELELARSRRVLRVPANRSALDVMLDWDPTTAYSCQQGFCGTC
Rv2776c|M.tuberculosis_H37Rv -VVDGVPFELELARSRRVLRVPANRSALDVMLDWDPTTAYSCQQGFCGTC
MMAR_1933|M.marinum_M -VVDGVPFELELARTGEVLSIPANRTALDVMLDRDPTTAYSCQQGFCGTC
MUL_2159|M.ulcerans_Agy99 -VVDGVPFELELARTGEVLSIPANRTALDVMLDRDPTTAYSCQQGFCGTC
MAV_4119|M.avium_104 -VVDGVPFELELARSRRVLTVPGNRSALDVMLDRDPATPYSCQQGFCGTC
..*. .* :. : : : : * .: ..*** ******
Mflv_3426|M.gilvum_PYR-GCK RTRVLSGEVDHRDTLLTDAERAA-GLMLPCVSRAAEGTVLALDL---
Mvan_3180|M.vanbaalenii_PYR-1 RTRVLAGSVEHRDTLLTGPERAA-GLMLTCVSRAGDGSGLTLDL---
TH_3804|M.thermoresistible__bu RTRVLDGTVEHRDRLLTEPERAA-GLMLTCVSRAPAGERLTLDL---
MAB_0088c|M.abscessus_ATCC_199 KVNVLAGTVDHRDQILTESQRDE-GQILTCVSRG-EG-RLVLDLPAE
MSMEG_4371|M.smegmatis_MC2_155 ETKVLAGEVDHRDDLLTDEERQANTTMMICVSRALGNAKLTLDL---
Mb2798c|M.bovis_AF2122/97 KVRVLAGQVDRRGRIIEGD-----NEMLVCVSRAVSG-RVVIDA---
Rv2776c|M.tuberculosis_H37Rv KVRVLAGQVDRRGRIIEGD-----NEMLVCVSRAVSG-RVVIDA---
MMAR_1933|M.marinum_M KVKVLAGQVDHRGRAAQGD-----DEMLVCVSRGHSA-RVVIDA---
MUL_2159|M.ulcerans_Agy99 KVKVLAGQVDHRGRAAQGD-----DEMLVCVSRGHSA-RVVIDA---
MAV_4119|M.avium_104 KVKVLAGQVDRRGRTVEGD-----DEMLVCVSRAKND-RLVIDA---
...** * *::*. :: ****. :.:*