For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NLTVSGRRDVATGVIELVLRRDDGQALAVWAPGAHIDFIVGPGVVRQYSLCGSPADRAHYRIAVLREEAG RGGSVAIHADAHIGSSFEVAGPRNNFALEPADSYLFIAGGIGITPIIPMVSAAVASDADWRLLYGGRQRT SMAYAEELEQLGPRVSIRPQDVDGLLDLDAVLSRCVAGTLIYCCGPEPLLAAVEDRCERRQLMSSLRLER FQARQPVVGGVDTDFEVELGSTGQVLSVPADRSILDVLRDYGIDVMSSCEEGVCGSCEIPVCSGIPDHRD SILTDEEREAGDRMMVCVSRSRSARLCLDVKPGEPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4152 | - | - | 100% (317) | phenoxybenzoate dioxygenase beta subunit |
| M. smegmatis MC2 155 | MSMEG_4371 | - | 4e-68 | 46.06% (317) | vanillate O-demethylase oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_3676 | - | 3e-62 | 44.27% (314) | phenoxybenzoate dioxygenase beta subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2798c | - | 7e-55 | 41.61% (310) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3426 | - | 1e-56 | 43.08% (318) | ferredoxin |
| M. tuberculosis H37Rv | Rv2776c | - | 7e-55 | 41.61% (310) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2381 | - | 1e-69 | 44.05% (311) | oxidoreductase |
| M. marinum M | MMAR_1933 | - | 2e-56 | 42.67% (307) | oxidoreductase |
| M. avium 104 | MAV_3669 | - | 9e-55 | 41.21% (313) | oxidoreductase |
| M. thermoresistible (build 8) | TH_4289 | - | 2e-76 | 48.40% (312) | PUTATIVE ferredoxin |
| M. ulcerans Agy99 | MUL_2159 | - | 6e-55 | 42.02% (307) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3180 | - | 3e-60 | 45.13% (308) | ferredoxin |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4152|M.smegmatis_MC2_155 --------------------------------------------------
TH_4289|M.thermoresistible__bu --------------------------------------------------
MAB_2381|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2798c|M.bovis_AF2122/97 --------------------------------------------------
Rv2776c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1933|M.marinum_M ------MAVSESSWTSRPADLYGRSHRDRFA-TALWGVRTMFGGFARFSR
MUL_2159|M.ulcerans_Agy99 ------MAVSESSWTSRPADLYGRSHRDRFA-TALWGVRTMFGGFARFSR
MAV_3669|M.avium_104 MSIRRAASRAPSIWASRPADLYGRRDHDRFT-AVLWGVRAVFEGFASVSR
Mflv_3426|M.gilvum_PYR-GCK ------------------MGVLGRLRYDVTIGLADAALHGMFATSAAMRR
Mvan_3180|M.vanbaalenii_PYR-1 ------MTRLFSQFRQTPPSPSGRLRHDVMLGIAETAIAGMFAASAAVRR
MSMEG_4152|M.smegmatis_MC2_155 ------------MNLTVSGRRDVAT--GVIELVLRRDDGQALAVWAPGAH
TH_4289|M.thermoresistible__bu --------MNMDLELHVAQKRTIAD--QIVELTLTRPDGGTLPEWTPGAH
MAB_2381|M.abscessus_ATCC_1997 -----MNDTGATLKVAVRQLRWEAD--GVVSLQLSSACNEPLPAWEPGAH
Mb2798c|M.bovis_AF2122/97 --------MRRTNPAVVTKRELVAP--DVVALTLADPGGGLLPAWSPGGH
Rv2776c|M.tuberculosis_H37Rv --------MRRTNPAVVTKRELVAP--DVVALTLADPGGGLLPAWSPGGH
MMAR_1933|M.marinum_M WNPSRVTPVGRTHRARVVERELVAP--DVVALTLADPDGGLLPSWSPGGH
MUL_2159|M.ulcerans_Agy99 WNPSRVTPVGRTHRARVVERELVAP--DVVALTLADPDGGLLPSWSPGGH
MAV_3669|M.avium_104 WHPARVKPVQRKLTAVVTKREFAAP--DVVALTLADPDGGLLPSWTPGAH
Mflv_3426|M.gilvum_PYR-GCK IRPP--DGVPETFPLTVTSRRVVARDQDVVELTLS---GDDLPRWHPGAH
Mvan_3180|M.vanbaalenii_PYR-1 VRMP--AAGPDTIPLTVTGRRVVAHDQDVVELTLA---GDRLPRWFPGAH
* . * :: * * . *. * **.*
MSMEG_4152|M.smegmatis_MC2_155 IDFIVGPGVVRQYSLCGSPADRAHYRIAVLREEAGRGGSVAIHADAHIGS
TH_4289|M.thermoresistible__bu IDLRLG-DLVRQYSLTGLEARPDRWVVSVLREPAGRGGSQYVHDVLAEGA
MAB_2381|M.abscessus_ATCC_1997 VDLVLPTGIERQYSLCGPVDDRSVYQVGVRRERTSRGGSEYVHAFLRPGQ
Mb2798c|M.bovis_AF2122/97 IDVQLPSGRRRQYSLCGVPGRRTDYRIAIRRIADGGGGSIEMHEAFDVGD
Rv2776c|M.tuberculosis_H37Rv IDVQLPSGRRRQYSLCGVPGRRTDYRIAIRRIADGGGGSIEMHEAFDVGD
MMAR_1933|M.marinum_M IDVQLPSGRRRQYSLCGPPGRRTDYRIAVRRIADGGGGSIEMHAAYQPGD
MUL_2159|M.ulcerans_Agy99 IDVQLPSRRRRQYSLCGPPGRRTDYRIAVRRIADGGGGSIEMHAAYQPGD
MAV_3669|M.avium_104 IDVLLPSGRRRQYSLCGPPGHRGEYRIAVRRIADGGGGSIEMHEAFGVGD
Mflv_3426|M.gilvum_PYR-GCK LDLHLPSGRIRQYSLCGEP-TAGHYRVAVRRIPDGGGGSVEVHDALPVGS
Mvan_3180|M.vanbaalenii_PYR-1 LDVHLPSGRVRQYSLCGDP-DSAEYRIAVRRIPDGGGGSVEVHDALEIGS
:*. : ***** * : :.: * . *** :* *
MSMEG_4152|M.smegmatis_MC2_155 SFEVAGPRNNFALEP------ADSYLFIAGGIGITPIIPMVSAAVASDAD
TH_4289|M.thermoresistible__bu SIGASLPRNHFPLRSD-----ADNILFIAGGIGITPMLPMISQLEQQART
MAB_2381|M.abscessus_ATCC_1997 QLRIKGPRNNFGLHR------ADGYLFIAAGIGITPILPMIRQAQDWGAD
Mb2798c|M.bovis_AF2122/97 TCEFEGPRNAFHL-----GLAERDVLFVIGGIGVTPILPMIRAAEQRGID
Rv2776c|M.tuberculosis_H37Rv TCEFEGPRNAFHL-----GLAERDVLFVIGGIGVTPILPMIRAAEQRGID
MMAR_1933|M.marinum_M ILVFEGPRNAFYL-----GAAEHDMLFVIGGIGVTPILPMVALAHQRGVN
MUL_2159|M.ulcerans_Agy99 ILVFEGPRNAFYL-----GAAEHDMLFVIGGIGVTPILPMVALAHQRGVN
MAV_3669|M.avium_104 TVEFEGPRNAFYL-----GTAEHDVLFVIGGIGVTPILPMIRVAAGRGID
Mflv_3426|M.gilvum_PYR-GCK TVRTHGPRNAFPLAVPGYGSPARRFRFIAGGIGITPILPMLALARSLGVD
Mvan_3180|M.vanbaalenii_PYR-1 TVHTHGPRNAFPLTVPGYGSPARRFRFIAGGIGITPILPMLGLARRLGVD
*** * * *: .***:**::**:
MSMEG_4152|M.smegmatis_MC2_155 WRLLYGGRQRTSMAYAEELEQLG-PRVSIRPQDVDG-LLDLDAVLSRCVA
TH_4289|M.thermoresistible__bu WNLIYCGRSRTSMAYLDELAKFG-DRVVVRPDDEYG-VPDLAGLIRPTAP
MAB_2381|M.abscessus_ATCC_1997 WTLYYGGHTAASMAFLEELRQYG-PRVHLYPADEVG-RIPLRELTTDVRP
Mb2798c|M.bovis_AF2122/97 WRAIYAGRGREYMPFLDEVVAVAPGRVTVWADDEHGRFASVDELLAGAGP
Rv2776c|M.tuberculosis_H37Rv WRAIYAGRGREYMPFLDEVVAVAPGRVTVWADDEHGRFASVDELLAGAGP
MMAR_1933|M.marinum_M WRAMYAGRSREYMPLLDELVAMAPERVSVWADDEHGRFAQVEDLVAGAGP
MUL_2159|M.ulcerans_Agy99 WRAVYAGRSREYMPLLDELVAMAPEGVSVWADDEHGRFAQVEDLVAGAGL
MAV_3669|M.avium_104 WRAIYTGRSREYMPLLDEVVSVDPQRVTVWADDEHGRFPTAAELLAAAGP
Mflv_3426|M.gilvum_PYR-GCK WSMVYTGRSADALPFVDEVAAFG-SPVEIRTDDRRG-LPTAAELLGDCPA
Mvan_3180|M.vanbaalenii_PYR-1 WSMVYTGRSVDSLPFVDEVTAFG-AAVDIRTDDRHG-LPAAAELLGDCAD
* * *: :. :*: * : . * * :
MSMEG_4152|M.smegmatis_MC2_155 GTLIYCCGPEPLLAAVEDRCERRQLMSSLRLERFQARQPVVGGVDTDFEV
TH_4289|M.thermoresistible__bu DTVVYSCGPEGMLSTLETVCADPAHSRTLVLERFVPKEYDTEG-DTAFEV
MAB_2381|M.abscessus_ATCC_1997 GLQIYACGPTELISDLTAAVS-HWPADTLHVERFKPIPCAPAE-DKPVDV
Mb2798c|M.bovis_AF2122/97 TTAVYVCGPPGMLEAVRVARNQHADAP-LHYERFSPPPVVDGV---PFEL
Rv2776c|M.tuberculosis_H37Rv TTAVYVCGPPGMLEAVRVARNQHADAP-LHYERFSPPPVVDGV---PFEL
MMAR_1933|M.marinum_M KTAVYVCGPPPMLEAVRAARAEYPCAP-LHYERFSPPPVVDGV---PFEL
MUL_2159|M.ulcerans_Agy99 KTAVYVCGPPPMLEAVRAARAEYPCAP-LHYERFSPPPVVDGV---PFEL
MAV_3669|M.avium_104 ATAVYVCGPSAMLEAVWIARNEHAGAP-LHYERFSPAPVVDGV---PFEL
Mflv_3426|M.gilvum_PYR-GCK DTSVYACGPAPMLTAVRDALVGRDDVE-LHFERFAAPPVVDGR---PFR-
Mvan_3180|M.vanbaalenii_PYR-1 GTAVYACGPAPMLTAVRAALVGRDDVE-LHFERFAAPPVTDGR---PFQA
:* *** :: : * *** . .
MSMEG_4152|M.smegmatis_MC2_155 ELGSTGQVLSVPADRSILDVLRDYGIDVMSSCEEGVCGSCEIPVCSGIPD
TH_4289|M.thermoresistible__bu EFAQSGVTVTVPADRSILEVAEEAGIDILSSCSEGTCGTCESPVLEGIPE
MAB_2381|M.abscessus_ATCC_1997 TCAASRQTIAVPPGQSILAAVEQAGIQVSASCRAGVCGSCETAVLEGVPD
Mb2798c|M.bovis_AF2122/97 ELARSRRVLRVPANRSALDVMLDWDPTTAYSCQQGFCGTCKVRVLAGQVD
Rv2776c|M.tuberculosis_H37Rv ELARSRRVLRVPANRSALDVMLDWDPTTAYSCQQGFCGTCKVRVLAGQVD
MMAR_1933|M.marinum_M ELARTGEVLSIPANRTALDVMLDRDPTTAYSCQQGFCGTCKVKVLAGQVD
MUL_2159|M.ulcerans_Agy99 ELARTGEVLSIPANRTALDVMLDRDPTTAYSCQQGFCGTCKVKVLAGQVD
MAV_3669|M.avium_104 ELARSRQVLAVPANRTALDVMLDRDATTPYSCRQGFCGTCRVKVLAGQVD
Mflv_3426|M.gilvum_PYR-GCK -VAAAGVTVDVGVDETLLAALGRAGVTTPYSCRQGFCGTCRTRVLSGEVD
Mvan_3180|M.vanbaalenii_PYR-1 TVASTGQQVDVGADETLLAALRRAGVDASYSCQQGFCGTCRTRVLAGSVE
. : : : ..: * . . ** * **:*. * * :
MSMEG_4152|M.smegmatis_MC2_155 HRDSILTDEEREAGDRMMVCVSRSRSAR-LCLDVKPGEPR
TH_4289|M.thermoresistible__bu HRDSVLTKEERASNATMMPCVSRCRTPR-LVLDL------
MAB_2381|M.abscessus_ATCC_1997 HRDDILSEEDRAAGDRMYICVSRALTPR-LVLDL------
Mb2798c|M.bovis_AF2122/97 RRGRIIEGDN-----EMLVCVSRAVSGR-VVIDA------
Rv2776c|M.tuberculosis_H37Rv RRGRIIEGDN-----EMLVCVSRAVSGR-VVIDA------
MMAR_1933|M.marinum_M HRGRAAQGDD-----EMLVCVSRGHSAR-VVIDA------
MUL_2159|M.ulcerans_Agy99 HRGRAAQGDD-----EMLVCVSRGHSAR-VVIDA------
MAV_3669|M.avium_104 HRGRTDPGQD-----GMLVCVSRADGGR-LVIDA------
Mflv_3426|M.gilvum_PYR-GCK HRDTLLTDAERAA-GLMLPCVSRAAEGTVLALDL------
Mvan_3180|M.vanbaalenii_PYR-1 HRDTLLTGPERAA-GLMLTCVSRAGDGSGLTLDL------
:*. : * **** : :*