For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
KIVVGYDGSLSANSAIRTSSELFPAAEAVIVYLSTPPFGSRGLRARLRHSARNVDELIDLVDRESEGESA RLVDLGVTLARAAGWTAEPLVKRTWAGEGLGLAQVGEELQPDVMVVGARGIGASESKIGSVSDLVVHHAP RPVLVVSQHMLSAEHQAVVDGPVVVGVDGSAGADRAIKAAEQLFPTRTVVSAAVDDGDAEGVDATHHVKR FRGSGAGATADALVAFADEQRAAAIVVGSRGRSALKKVLLGSVAGATLQRTFRPVLVVPGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4362 | - | - | 100% (272) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3936 | - | 2e-12 | 27.24% (301) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3950 | - | 7e-10 | 24.43% (307) | universal stress protein family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2051c | - | 4e-10 | 25.00% (304) | hypothetical protein Mb2051c |
| M. gilvum PYR-GCK | Mflv_5002 | - | 3e-63 | 47.65% (277) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2026c | - | 5e-10 | 25.00% (304) | hypothetical protein Rv2026c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3843 | - | 1e-05 | 22.77% (303) | hypothetical protein MAB_3843 |
| M. marinum M | MMAR_0859 | - | 2e-69 | 50.55% (275) | universal stress protein UspA |
| M. avium 104 | MAV_2494 | - | 4e-10 | 30.94% (181) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 7e-11 | 28.48% (302) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_0611 | - | 5e-62 | 49.41% (253) | hypothetical protein MUL_0611 |
| M. vanbaalenii PYR-1 | Mvan_1372 | - | 3e-67 | 51.07% (280) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2051c|M.bovis_AF2122/97 ---------MSAATAKYGILVGVDGSAQSNAAVAWAAREAVMRQLPITLL
Rv2026c|M.tuberculosis_H37Rv ---------MSAATAKYGILVGVDGSAQSNAAVAWAAREAVMRQLPITLL
TH_2494|M.thermoresistible__bu ---------VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLV
MAV_2494|M.avium_104 ----------------------------------------------MRTI
MMAR_0859|M.marinum_M --------------MPVNAVVGYDGSPGASTAIEAGALLFPGARGWITYL
MUL_0611|M.ulcerans_Agy99 MAGLVARDLSRRCTVPVNAVVGYDGSPGASTAIEAGALLFPGARGWITYL
MSMEG_4362|M.smegmatis_MC2_155 ----------------MKIVVGYDGSLSANSAIRTSSELFPAAEAVIVYL
Mflv_5002|M.gilvum_PYR-GCK --------------MPANVMVGYDGSPAACAAINAGAALFPNAHAWIAHI
Mvan_1372|M.vanbaalenii_PYR-1 --------------MPTNLIVGYDGSPAANAAINAGAQLFPSAHAWIAHI
MAB_3843|M.abscessus_ATCC_1997 ----------------MTVVVGYLSGKGGKGALHLAVESARVLETSLTVT
:
Mb2051c|M.bovis_AF2122/97 HIVAPVVVG----WPVGQLYANMTEWQKDNAQQVIEQAREALTNSLGESK
Rv2026c|M.tuberculosis_H37Rv HIVAPVVVG----WPVGQLYANMTEWQKDNAQQVIEQAREALTNSLGESK
TH_2494|M.thermoresistible__bu HVMTATSIGAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEAR
MAV_2494|M.avium_104 RTAAAFSSG---------LYLRVVGFPGD-------CSFGIAPSSFPRSG
MMAR_0859|M.marinum_M WVPPFASEK--VRRRLRPMASNTNELVEMVEREGELEARRVVAMGATLAR
MUL_0611|M.ulcerans_Agy99 WVPPFASEK--VRRRLRPMASNTNELVEMVEREGELEARRVVAMGATLAR
MSMEG_4362|M.smegmatis_MC2_155 STPPFGSRG--LRARLRHSARNVDELIDLVDRESEGESARLVDLGVTLAR
Mflv_5002|M.gilvum_PYR-GCK WQPPFAGKR--LRRRLRAAARTADELAELIEREGAREADTIASAGVALAK
Mvan_1372|M.vanbaalenii_PYR-1 WTPPFTSKR--LRRRLRAAAESADDLAELIEREGAREADNIVGAGVALAK
MAB_3843|M.abscessus_ATCC_1997 TVVPKPWTT----LSKAKIDAEYAQWAQKLSDDSKSEATAYLEKIGAGID
. :
Mb2051c|M.bovis_AF2122/97 PP----------QVHTELVFSNVVPTLIDASQQAWLMVVGSQGMGALGRL
Rv2026c|M.tuberculosis_H37Rv PP----------QVHTELVFSNVVPTLIDASQQAWLMVVGSQGMGALGRL
TH_2494|M.thermoresistible__bu AAGPGPAGDDAVRVVTGVVRAAPVPTLVDASKQAKLVAVGSRGQGPLRRV
MAV_2494|M.avium_104 AS----------RISRAIHYSAPVPALLELSGAVRMLVLGSAGHGLLARG
MMAR_0859|M.marinum_M AAGWDAEP----VLKRTWGPEGLRMAEEADEVQADLVLVGTRGLG-GTQA
MUL_0611|M.ulcerans_Agy99 AAGWDAEP----VLKRTWGPEGLRMAEEADEVQADLVLVGTRGLG-GTQA
MSMEG_4362|M.smegmatis_MC2_155 AAGWTAEP----LVKRTWAGEGLGLAQVGEELQPDVMVVGARGIG-ASES
Mflv_5002|M.gilvum_PYR-GCK AAEWDAEP----VVKRTYGSDGMRLSQLAEQMHSDVLVLGDRGLD-ATDA
Mvan_1372|M.vanbaalenii_PYR-1 AAEWDAEP----VVKRTIGSDGLRLAQLAERLHTDVVVVGDRGLG-RTEA
MAB_3843|M.abscessus_ATCC_1997 VT----------FHNVAHRSVSGGLLEAVEASDADVLVVGSASEGRLGQV
. :: :* . .
Mb2051c|M.bovis_AF2122/97 LLGSISTALLHHARCPVAIIHSG--NGATPD-SDAPVLVG--IDGSPASE
Rv2026c|M.tuberculosis_H37Rv LLGSISTALLHHARCPVAIIHSG--NGATPD-SDAPVLVG--IDGSPASE
TH_2494|M.thermoresistible__bu LLGSVSSGLVHHAHCPVAVIREG--TPHTPDFAKRPVLVG--IDGSESAQ
MAV_2494|M.avium_104 LLGSVSSAVVRHANCPVAVVRD----EELPDPHSAPVLLG--TDGSPASE
MMAR_0859|M.marinum_M VLGSVADMVLHRCPRPVVVVPNPMLAAEYDALPKGPMVVG--WDGSAGSE
MUL_0611|M.ulcerans_Agy99 VLGSVADMVLHRCPRPVVVVPNPMLAAEYDALPKGPMVVG--WDGSAGSE
MSMEG_4362|M.smegmatis_MC2_155 KIGSVSDLVVHHAPRPVLVVSQHMLSAEHQAVVDGPVVVG--VDGSAGAD
Mflv_5002|M.gilvum_PYR-GCK VIGSVSDMAVHYSTVPVLVVPNPLLAEEFAALARGPIVVA--FDGSPGAD
Mvan_1372|M.vanbaalenii_PYR-1 VIGSVSDMVVHYSTVPVLVVPNPLLTEEYAALAHGPVVVG--YDGSAAAE
MAB_3843|M.abscessus_ATCC_1997 VLGSTGDRLLHSSPVPLAISPRGYRGSRAGTVSRVTCGYPGTEDAVDVVQ
:** . :: . *: : . *. :
Mb2051c|M.bovis_AF2122/97 AATALAFDEASRRRVDLVALHAWTDLGMFPVLGMDWREREKREAEVLAER
Rv2026c|M.tuberculosis_H37Rv AATALAFDEASRRRVDLVALHAWTDLGMFPVLGMDWREREKREAEVLAER
TH_2494|M.thermoresistible__bu RATAVAFEEASFRGVDLIALHAWSDADIADIPTLELSAVQQSAERVLSER
MAV_2494|M.avium_104 LATEIAFDEASRRGVDLVAIHAWSDTAVTEVFEIDWPIVEAEAERHLAES
MMAR_0859|M.marinum_M TALAAARRLCPDREVVLVFVGDGS------------VPPPAAGVGELRQL
MUL_0611|M.ulcerans_Agy99 TALAAARRLCPDREVVLVFVGDGS------------APPPAAGVGELRQL
MSMEG_4362|M.smegmatis_MC2_155 RAIKAAEQLFPTRTVVSAAVDDG----------------DAEGVDAT--H
Mflv_5002|M.gilvum_PYR-GCK AAAEKARTLFPDREVVLAGVRDEDDD--------PAARQWPDDVEVLATS
Mvan_1372|M.vanbaalenii_PYR-1 AATDTARRLFPDRKVILAAVRDDDRD--------VVAGPATEGLEMLTVD
MAB_3843|M.abscessus_ATCC_1997 QAVRLTQRLHAPLRVVTFAVRGRTMLTAGVGPEAEDAVLASWVTQSEEAL
* : . * :
Mb2051c|M.bovis_AF2122/97 LAGWQEQYPDVRVHRSLVCDKPARWLLE--HSEQAQLVVVGSHGRGGFSG
Rv2026c|M.tuberculosis_H37Rv LAGWQEQYPDVRVHRSLVCDKPARWLLE--HSEQAQLVVVGSHGRGGFSG
TH_2494|M.thermoresistible__bu LAGFRERYPDVSVHRRIVGSEPARHLVE--ASEDAQLVVVGSRGRGGFTG
MAV_2494|M.avium_104 LAGWQERYPDVTVHRLVARDRAAQHIIS--SSETAQLVVVGSHGRGGLAR
MMAR_0859|M.marinum_M SVERGRGFHARAVSEALVAAG---------QDNGAALLVVGSRGHSGARE
MUL_0611|M.ulcerans_Agy99 SVERGRGFHARAVSEALVAAG---------QDNGAALLVVGSRGHSGARE
MSMEG_4362|M.smegmatis_MC2_155 HVKRFRGSGAGATADALVAFA---------DEQRAAAIVVGSRGRSALKK
Mflv_5002|M.gilvum_PYR-GCK EPNWLGRPRDRATADALIDFA---------DRRDAAVLVVGSRGRSAVRE
Mvan_1372|M.vanbaalenii_PYR-1 ETNWFGRARDRAIADELIAVG---------DRSDAAVLVVGSRGRSPARE
MAB_3843|M.abscessus_ATCC_1997 SELRQAGIVTADVELKVVTGDTWDDALDNAEWNDGELLVLGSRPHSAVAR
: . :*:**: :.
Mb2051c|M.bovis_AF2122/97 MLLGSVSSAVAHSVRIPVI----------VVRPS----------------
Rv2026c|M.tuberculosis_H37Rv MLLGSVSSAVAHSVRIPVI----------VVRPS----------------
TH_2494|M.thermoresistible__bu MLLGSVSRAVVNAVTTPVI----------VAR------------------
MAV_2494|M.avium_104 LLLGSVSNAVLHSVRVPVI----------VARPPA---------------
MMAR_0859|M.marinum_M TLLGSVAMGTVHHSHRPVL----------VVPSGWQVPADS---------
MUL_0611|M.ulcerans_Agy99 TLRARDIAWQRRNGHRAPLPSAGPGGAERVAGSRRLLSADGALGPRSARW
MSMEG_4362|M.smegmatis_MC2_155 VLLGSVAGATLQRTFRPVL----------VVPGG----------------
Mflv_5002|M.gilvum_PYR-GCK VLLGSVAVAAVNRSHRPVM----------VVHS-----------------
Mvan_1372|M.vanbaalenii_PYR-1 VLLGSVAVATVHRSHRPVL----------VVHS-----------------
MAB_3843|M.abscessus_ATCC_1997 VFLGSRATKIVRHSPVPVV----------VMPG-----------------
: . . . : *
Mb2051c|M.bovis_AF2122/97 ----------
Rv2026c|M.tuberculosis_H37Rv ----------
TH_2494|M.thermoresistible__bu ----------
MAV_2494|M.avium_104 ----------
MMAR_0859|M.marinum_M ----------
MUL_0611|M.ulcerans_Agy99 VTSGSDPAGV
MSMEG_4362|M.smegmatis_MC2_155 ----------
Mflv_5002|M.gilvum_PYR-GCK ----------
Mvan_1372|M.vanbaalenii_PYR-1 ----------
MAB_3843|M.abscessus_ATCC_1997 ----------