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PANVMVGYDGSPAACAAINAGAALFPNAHAWIAHIWQPPFAGKRLRRRLRAAARTADELAELIEREGARE ADTIASAGVALAKAAEWDAEPVVKRTYGSDGMRLSQLAEQMHSDVLVLGDRGLDATDAVIGSVSDMAVHY STVPVLVVPNPLLAEEFAALARGPIVVAFDGSPGADAAAEKARTLFPDREVVLAGVRDEDDDPAARQWPD DVEVLATSEPNWLGRPRDRATADALIDFADRRDAAVLVVGSRGRSAVREVLLGSVAVAAVNRSHRPVMVV HS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5002 | - | - | 100% (283) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4992 | - | 1e-15 | 27.45% (306) | UspA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_4382 | - | 1e-13 | 27.63% (304) | UspA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2019 | - | 2e-10 | 26.95% (308) | hypothetical protein Mb2019 |
| M. tuberculosis H37Rv | Rv1996 | - | 2e-10 | 26.95% (308) | hypothetical protein Rv1996 |
| M. leprae Br4923 | MLBr_01390 | - | 2e-05 | 39.66% (58) | hypothetical protein MLBr_01390 |
| M. abscessus ATCC 19977 | MAB_3843 | - | 1e-08 | 28.00% (200) | hypothetical protein MAB_3843 |
| M. marinum M | MMAR_0859 | - | 3e-73 | 49.47% (283) | universal stress protein UspA |
| M. avium 104 | MAV_2507 | - | 5e-11 | 26.38% (307) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_4362 | - | 3e-63 | 47.65% (277) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_4471 | - | 5e-13 | 28.28% (297) | PUTATIVE putative universal stress protein family protein |
| M. ulcerans Agy99 | MUL_0611 | - | 1e-65 | 48.09% (262) | hypothetical protein MUL_0611 |
| M. vanbaalenii PYR-1 | Mvan_1372 | - | 1e-118 | 74.56% (283) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5002|M.gilvum_PYR-GCK --------------MPANVMVGYDGSPAACAAINAGA--ALFPNAHAWIA
Mvan_1372|M.vanbaalenii_PYR-1 --------------MPTNLIVGYDGSPAANAAINAGA--QLFPSAHAWIA
MMAR_0859|M.marinum_M --------------MPVNAVVGYDGSPGASTAIEAGA--LLFPGARGWIT
MUL_0611|M.ulcerans_Agy99 MAGLVARDLSRRCTVPVNAVVGYDGSPGASTAIEAGA--LLFPGARGWIT
MSMEG_4362|M.smegmatis_MC2_155 ----------------MKIVVGYDGSLSANSAIRTSS--ELFPAAEAVIV
Mb2019|M.bovis_AF2122/97 ---------MSAQQTNLGIVVGVDGSPCSHTAVEWAARDAQMRNVALRVV
Rv1996|M.tuberculosis_H37Rv ---------MSAQQTNLGIVVGVDGSPCSHTAVEWAARDAQMRNVALRVV
MAV_2507|M.avium_104 ---------MAASSKRCGVLVGVDGSPASNFAVCWAARDAAMRNVPLTLV
TH_4471|M.thermoresistible__bu ---------MAIPAIQDSIVAGVDGSPSSAAAVEWAARNAALRDRPLVLV
MLBr_01390|M.leprae_Br4923 ------------MGAYQTVVVGTDGSDSSLRAVDRAG-KIAGSDAKLIIA
MAB_3843|M.abscessus_ATCC_1997 ----------------MTVVVGYLSGKGGKGALHLAVESARVLETSLTVT
:.* .. . *: . :.
Mflv_5002|M.gilvum_PYR-GCK HIWQPPFAGKRLRRRLRAAARTADELAELIEREGAREADTIASAGVALAK
Mvan_1372|M.vanbaalenii_PYR-1 HIWTPPFTSKRLRRRLRAAAESADDLAELIEREGAREADNIVGAGVALAK
MMAR_0859|M.marinum_M YLWVPPFASEKVRRRLRPMASNTNELVEMVEREGELEARRVVAMGATLAR
MUL_0611|M.ulcerans_Agy99 YLWVPPFASEKVRRRLRPMASNTNELVEMVEREGELEARRVVAMGATLAR
MSMEG_4362|M.smegmatis_MC2_155 YLSTPPFGSRGLRARLRHSARNVDELIDLVDRESEGESARLVDLGVTLAR
Mb2019|M.bovis_AF2122/97 QVVPPVITAPEGWAFEYSRFQEAQKREIVEHSYLVAQAHQIVEQAHKVAL
Rv1996|M.tuberculosis_H37Rv QVVPPVITAPEGWAFEYSRFQEAQKREIVEHSYLVAQAHQIVEQAHKVAL
MAV_2507|M.avium_104 HMVNAATV----WPQVP---MAAEAVAWQED-----DGRRVLQEAVKIAE
TH_4471|M.thermoresistible__bu HVVPSPMVTTAPWPQLP---LPDDAFRVMQE-----EGERLLAQARAAAE
MLBr_01390|M.leprae_Br4923 SAYLPQHDNARAFDILKDESYKVTG-----------TAPIYEILHDAKER
MAB_3843|M.abscessus_ATCC_1997 TVVPKPWTTLSKAKIDAEYAQWAQKLS---------DDSKSEATAYLEKI
Mflv_5002|M.gilvum_PYR-GCK AAEWDAEPVVKRTYGSDGMRLSQLAEQ-MHSDVLVLGDRGLDATD-AVIG
Mvan_1372|M.vanbaalenii_PYR-1 AAEWDAEPVVKRTIGSDGLRLAQLAER-LHTDVVVVGDRGLGRTE-AVIG
MMAR_0859|M.marinum_M AAGWDAEPVLKRTWGPEGLRMAEEADE-VQADLVLVGTRGLGGTQ-AVLG
MUL_0611|M.ulcerans_Agy99 AAGWDAEPVLKRTWGPEGLRMAEEADE-VQADLVLVGTRGLGGTQ-AVLG
MSMEG_4362|M.smegmatis_MC2_155 AAGWTAEPLVKRTWAGEGLGLAQVGEE-LQPDVMVVGARGIGASE-SKIG
Mb2019|M.bovis_AF2122/97 EASSSGRAAQITGEVLHGQIVPTLANISRQVAMVVLGYRGQGAVAGALLG
Rv1996|M.tuberculosis_H37Rv EASSSGRAAQITGEVLHGQIVPTLANISRQVAMVVLGYRGQGAVAGALLG
MAV_2507|M.avium_104 DATRNGRNLAITTELWHAPPAPTLAQLSEEAELVVVGSTGRGAIGRLLLG
TH_4471|M.thermoresistible__bu QAGAG----EVRTAVLQAGIVGTLTELSRDADRIVVGSRGQTALGRMLLG
MLBr_01390|M.leprae_Br4923 AHAAGAKNVEERPVVGAPVDALVNLAEKTNADLLVVGNVGLSTIAGRLLG
MAB_3843|M.abscessus_ATCC_1997 GAGIDVTFHNVAHRSVSGGLLEAVEAS--DADVLVVGSASEGRLGQVVLG
. :::* . :*
Mflv_5002|M.gilvum_PYR-GCK SVSDMAVHYSTVPVLVVPNPLLAEEFAALARGPIVVAFDGSPGADAAAEK
Mvan_1372|M.vanbaalenii_PYR-1 SVSDMVVHYSTVPVLVVPNPLLTEEYAALAHGPVVVGYDGSAAAEAATDT
MMAR_0859|M.marinum_M SVADMVLHRCPRPVVVVPNPMLAAEYDALPKGPMVVGWDGSAGSETALAA
MUL_0611|M.ulcerans_Agy99 SVADMVLHRCPRPVVVVPNPMLAAEYDALPKGPMVVGWDGSAGSETALAA
MSMEG_4362|M.smegmatis_MC2_155 SVSDLVVHHAPRPVLVVSQHMLSAEHQAVVDGPVVVGVDGSAGADRAIKA
Mb2019|M.bovis_AF2122/97 SVSSSLVRHAHGPVAVIPEEPRP-ARPPH--APVVVGIDGSPTSGLAAEI
Rv1996|M.tuberculosis_H37Rv SVSSSLVRHAHGPVAVIPEEPRP-ARPPH--APVVVGIDGSPTSGLAAEI
MAV_2507|M.avium_104 SVSSGLVRRARCPVAVIHDEDPMMPYPQR--APVLVGIDGSPASELATAI
TH_4471|M.thermoresistible__bu SVSTGLVHQAECPVVIVRDGD---QPPGD--APVLVGIDGSPASELATEV
MLBr_01390|M.leprae_Br4923 SVPANVSRRAKIDVLIVHTTH-----------------------------
MAB_3843|M.abscessus_ATCC_1997 STGDRLLHSSPVPLAISPRGYRGSRAGTVS--RVTCGYPGTEDAVDVVQQ
*. : . : :
Mflv_5002|M.gilvum_PYR-GCK ARTLFPDREVVLAGVRDEDDD-------------PAARQWPDDVEVLATS
Mvan_1372|M.vanbaalenii_PYR-1 ARRLFPDRKVILAAVRDDDRD-------------VVAGPATEGLEMLTVD
MMAR_0859|M.marinum_M ARRLCPDREVVLVFVGDGS-----------------VPPPAAGVGELRQL
MUL_0611|M.ulcerans_Agy99 ARRLCPDREVVLVFVGDGS-----------------APPPAAGVGELRQL
MSMEG_4362|M.smegmatis_MC2_155 AEQLFPTRTVVSAAVDDG---------------------DAEGVDAT--H
Mb2019|M.bovis_AF2122/97 AFDEASRRGVDLVALHAWSDMGPLDFPRLNWAPIEWRNLEDEQEKMLARR
Rv1996|M.tuberculosis_H37Rv AFDEASRRGVDLVALHAWSDMGPLDFPRLNWAPIEWRNLEDEQEKMLARR
MAV_2507|M.avium_104 AFDEALRRGVDLNAVHAWSDTQVFGLP-----GMDWPAVRSQAERSLAER
TH_4471|M.thermoresistible__bu AFEEASVRQVELVALHGWRDTSLFHYP-----GLDTESLQTQAEAVLAER
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
MAB_3843|M.abscessus_ATCC_1997 AVRLTQRLHAPLRVVTFAVRG----------RTMLTAGVGPEAEDAVLAS
Mflv_5002|M.gilvum_PYR-GCK EPNWLGRPRDRATADALIDFADR------------------RDAAVLVVG
Mvan_1372|M.vanbaalenii_PYR-1 ETNWFGRARDRAIADELIAVGDR------------------SDAAVLVVG
MMAR_0859|M.marinum_M SVERGRGFHARAVSEALVAAGQD------------------NGAALLVVG
MUL_0611|M.ulcerans_Agy99 SVERGRGFHARAVSEALVAAGQD------------------NGAALLVVG
MSMEG_4362|M.smegmatis_MC2_155 HVKRFRGSGAGATADALVAFADE------------------QRAAAIVVG
Mb2019|M.bovis_AF2122/97 LSGWQDRYPDVVVHKVVVCDRPAPRLLE-----------LAQTAQLVVVG
Rv1996|M.tuberculosis_H37Rv LSGWQDRYPDVVVHKVVVCDRPAPRLLE-----------LAQTAQLVVVG
MAV_2507|M.avium_104 LAGWQERYPDVTVHRMVVCDRPARQLIE-----------QSESAQLTVVG
TH_4471|M.thermoresistible__bu LAGWQERYPDVTVRRVVVAEHPARALVQ-----------RAEEAQLVVVG
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
MAB_3843|M.abscessus_ATCC_1997 WVTQSEEALSELRQAGIVTADVELKVVTGDTWDDALDNAEWNDGELLVLG
Mflv_5002|M.gilvum_PYR-GCK SRGRSAVREVLLGSVAVAAVNRSHRPVM----------VVHS--------
Mvan_1372|M.vanbaalenii_PYR-1 SRGRSPAREVLLGSVAVATVHRSHRPVL----------VVHS--------
MMAR_0859|M.marinum_M SRGHSGARETLLGSVAMGTVHHSHRPVL----------VVPSGWQVPADS
MUL_0611|M.ulcerans_Agy99 SRGHSGARETLRARDIAWQRRNGHRAPLPSAGPGGAERVAGSRRLLSADG
MSMEG_4362|M.smegmatis_MC2_155 SRGRSALKKVLLGSVAGATLQRTFRPVL----------VVPGG-------
Mb2019|M.bovis_AF2122/97 SHGRGGFPGMHLGSVSRAVVNSGQAPVI----------VARIPQDPAVPA
Rv1996|M.tuberculosis_H37Rv SHGRGGFPGMHLGSVSRAVVNSGQAPVI----------VARIPQDPAVPA
MAV_2507|M.avium_104 SHGRGGLAGTLLGSVSNAVVHSVRMPVI----------VARPS-------
TH_4471|M.thermoresistible__bu SRGRSGLTGKLLGSVSTGVVHSVRVPVM----------VARPR-------
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
MAB_3843|M.abscessus_ATCC_1997 SRPHSAVARVFLGSRATKIVRHSPVPVV----------VMPG--------
Mflv_5002|M.gilvum_PYR-GCK -------------------
Mvan_1372|M.vanbaalenii_PYR-1 -------------------
MMAR_0859|M.marinum_M -------------------
MUL_0611|M.ulcerans_Agy99 ALGPRSARWVTSGSDPAGV
MSMEG_4362|M.smegmatis_MC2_155 -------------------
Mb2019|M.bovis_AF2122/97 -------------------
Rv1996|M.tuberculosis_H37Rv -------------------
MAV_2507|M.avium_104 -------------------
TH_4471|M.thermoresistible__bu -------------------
MLBr_01390|M.leprae_Br4923 -------------------
MAB_3843|M.abscessus_ATCC_1997 -------------------