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FASRLRKLIQSSATVAVVATAAAACGGGSATDQPVGEPVYGGSLAFYDPVEYNAWTPVNSIWSNSQVSNN LAERLIWQDPITGEYKPWLAESYQTSDDHLAYTFKLRSGVTFSDGTPLDAAVVKANFDQHGFGDESLGIT QDPFWTDYAGTDVVDDSTVVVRLSKPNAGFIQILSNYRASSILGKSTLEKDLNGQSDLRNWVGTGPFVVE SVEGTTGVTLKRRDDYDWAPEGSKHSGKAYLERIVFKTVPEAGTRVGALQSGEAQIARNIAPYDEETVAA GGGTLLAIPVQGETNDLTVRLDNPNSPLQDKQVRLALQAATDRQAINQAVLSPNYPIPSGALVKGTPLRG DSSRYLQHDLEKAKSLLDAAGWKPGPDGIRVKDGKRLSIHQRVAPYYQVSQSVLEVLQSQWREAGVEIKL TSPSLTEYEAQEQSATDWFLTQGQTSTAEPSVLRTSYGSNRQNVTEKSPPDAKLDELLVAQSYEFDPEKR KAAIQAIEDHIFSEGYSIPLYDETQVFGLGPTVQGFTTESTGRSWFYDTWLNG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_4101 | - | - | 100% (544) | ABC-type transporter, substrate binding protein |
M. smegmatis MC2 155 | MSMEG_2847 | - | 7e-82 | 36.81% (546) | extracellular solute-binding protein, family protein 5 |
M. smegmatis MC2 155 | MSMEG_4385 | - | 2e-47 | 28.91% (543) | ABC transporter oligopeptide binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1311c | oppA | 7e-17 | 25.17% (437) | periplasmic oligopeptide-binding lipoprotein OppA |
M. gilvum PYR-GCK | Mflv_2761 | - | 2e-30 | 25.05% (527) | extracellular solute-binding protein |
M. tuberculosis H37Rv | Rv1280c | oppA | 7e-17 | 25.17% (437) | periplasmic oligopeptide-binding lipoprotein OppA |
M. leprae Br4923 | MLBr_01121 | - | 6e-13 | 23.76% (463) | putative extracellular solute-binding dependent transport |
M. abscessus ATCC 19977 | MAB_0426 | - | 4e-10 | 28.48% (309) | peptide ABC transporter DppA |
M. marinum M | MMAR_4139 | oppA | 5e-12 | 23.56% (433) | periplasmic oligopeptide-binding lipoprotein OppA |
M. avium 104 | MAV_3421 | - | 1e-74 | 34.85% (528) | extracellular solute-binding protein, family protein 5 |
M. thermoresistible (build 8) | TH_4152 | - | 8e-26 | 24.95% (541) | PUTATIVE extracellular solute-binding protein, family 5 |
M. ulcerans Agy99 | MUL_4002 | oppA | 3e-11 | 23.27% (434) | periplasmic oligopeptide-binding lipoprotein OppA |
M. vanbaalenii PYR-1 | Mvan_3773 | - | 3e-27 | 23.83% (470) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2761|M.gilvum_PYR-GCK -----------------------------MARTAVGAAVLAVCALVLSLT Mvan_3773|M.vanbaalenii_PYR-1 ----------------------------------MRTVVLATCVFLAALT TH_4152|M.thermoresistible__bu -------------------------------------VSNLVAVLLIAAT MMAR_4139|M.marinum_M MLTNADR---HDGVQPGPGARSRRPTRPWAR-RRIRCAGAALLTVTLLLA MUL_4002|M.ulcerans_Agy99 -----------------------------------------MLTVTLLLA Mb1311c|M.bovis_AF2122/97 MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLT Rv1280c|M.tuberculosis_H37Rv MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLT MLBr_01121|M.leprae_Br4923 -------------------------------MIMLSRIVAALLVVGLILT MSMEG_4101|M.smegmatis_MC2_155 -----------------------------MFASRLRKLIQSSATVAVVAT MAV_3421|M.avium_104 -------------------------------MAKVASRTATLGAMLCVLA MAB_0426|M.abscessus_ATCC_1997 ----------------------------------MRLRRLAIVLLVGIVA . : Mflv_2761|M.gilvum_PYR-GCK GCNTG-ERVDLGDGAGGALIAAIAGEPDQLDPHKTT----AYFSFEVLEN Mvan_3773|M.vanbaalenii_PYR-1 GCSPG-DRVDLGAGAADALIAAIAGEPDQLDPHKTT----SYFSFEVLEN TH_4152|M.thermoresistible__bu GCAPG-QRVDLGD-LSGNLIAAIAGEPDQLDPHKTS----AYFSFQVLEN MMAR_4139|M.marinum_M GCSAS-TQLPAATSGS--TAVGSSSDINPQDPATLEDGGDLRLSLTDFPP MUL_4002|M.ulcerans_Agy99 GCSAS-TQLPAATSGS--TAVGSSSDINPQDPATLEDGGDLRLSLTDFPP Mb1311c|M.bovis_AF2122/97 GCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPP Rv1280c|M.tuberculosis_H37Rv GCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPP MLBr_01121|M.leprae_Br4923 GCSAS-NRLVPSAASN--AALGKTSDINPQDPATLKDGGNLRLALTDFPA MSMEG_4101|M.smegmatis_MC2_155 AAAACGGGSATDQPVGEPVYGGSLAFYDPVEYNAWTPVNSIWSNSQVSNN MAV_3421|M.avium_104 AGCSGHRHTASTGPTGPPVRGGTLTYSDVQFVTDTMAAN--YSANNLMFQ MAB_0426|M.abscessus_ATCC_1997 VLPAGCGDLVTPAPPGYFSMYITEPEHTLVPGNTTE-----NQGGRILRS . Mflv_2761|M.gilvum_PYR-GCK VFDTLVE----PDQDLQMKPALAESWEVSPD------------------- Mvan_3773|M.vanbaalenii_PYR-1 VFDTLVE----PDGNLQMQPALARAWEVSPD------------------- TH_4152|M.thermoresistible__bu VFDTLVE----PDEDLRMRPALAESWQVSAD------------------- MMAR_4139|M.marinum_M NFNILHIDGNSAEVAAMVKATLPRAFIIGPDGSTTVDHDYFTSVELTKTN MUL_4002|M.ulcerans_Agy99 NFNILHIDGNSAEVAAMVKATLPRAFIIGPDGSTTVDHDYFTSVELTKTN Mb1311c|M.bovis_AF2122/97 NFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTA Rv1280c|M.tuberculosis_H37Rv NFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTA MLBr_01121|M.leprae_Br4923 NFNILHIDGNNAEVTSMMKATMPRAFIIGTDGSTTVDTNYFTSIKLTSTS MSMEG_4101|M.smegmatis_MC2_155 LAERLIWQ---DPITGEYKPWLAESYQTSDD------------------- MAV_3421|M.avium_104 LLDRVVY---VDPKTDAVRGWLAKTFSRNQN------------------- MAB_0426|M.abscessus_ATCC_1997 LFTALVEFN--NETAAVEYTGVAESITSHDN------------------- : :..: : Mflv_2761|M.gilvum_PYR-GCK QLTWTFRLRPGVTFHDGTPLAAEDVVFSYRRIID-----EQLANSD---- Mvan_3773|M.vanbaalenii_PYR-1 QLTWTFHLRPGVTFHDGTPLTADDVVFSYRRIID-----EQLANSD---- TH_4152|M.thermoresistible__bu QRVWTFRLRPGVTFHDGSPLTADDVVFSYRRIID-----EHLTNVD---- MMAR_4139|M.marinum_M PQVITYTINPKAFWSDGTPITWRDIASQIHATSGADNRFEIASSGG---- MUL_4002|M.ulcerans_Agy99 PQVITYTINPKAFWSDGTPVTWRDIASQIHATSGADNRFEIASSGG---- Mb1311c|M.bovis_AF2122/97 PQVVTYTINPEAVWSDGTPITWRDIASQIHAISGADKAFEIASSSG---- Rv1280c|M.tuberculosis_H37Rv PQVVTYTINPEAVWSDGTPITWRDIASQIHAISGADKAFEIASSSG---- MLBr_01121|M.leprae_Br4923 PQVVTYTINPKAVWSDGTPITWRDIDRQIHANSGKNKAFEIAGTNG---- MSMEG_4101|M.smegmatis_MC2_155 HLAYTFKLRSGVTFSDGTPLDAAVVKANFDQHGFGDESLGITQDP----- MAV_3421|M.avium_104 ATRYTFTIRDGVSFSDHTPLTAEVVKANFDQLGKGDPAKKMPAFAD---- MAB_0426|M.abscessus_ATCC_1997 -VNWTIKLKPGWTFHNGEPVTAQSYVDAWNYTALSTNAQGSSSFLANVDG * :. : : *: Mflv_2761|M.gilvum_PYR-GCK --------------KFSSVQAVEAPDPSTVVIRVDRPTPNMLTNLGG--- Mvan_3773|M.vanbaalenii_PYR-1 --------------KFSSVAAVDAPDPNTVVIRVDRPTPNMLTNLGG--- TH_4152|M.thermoresistible__bu --------------RLSAVTEVTAVDPLTVRITVARPTPNLLTNLGG--- MMAR_4139|M.marinum_M --------------SDRVASVTPGVDDRQAIVTFAKPYAEWRGMFAGNGM MUL_4002|M.ulcerans_Agy99 --------------SDRVASVIPGVDDRQAMVTFAKPYAEWRGMFAGNGM Mb1311c|M.bovis_AF2122/97 --------------AERVASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGM Rv1280c|M.tuberculosis_H37Rv --------------AERVASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGM MLBr_01121|M.leprae_Br4923 --------------CERVASIRPGANDRQAIVTFAQPYAEWRGMFAGNGM MSMEG_4101|M.smegmatis_MC2_155 --------------FWTDYAGTDVVDDSTVVVRLSKPNAGFIQILSNYRA MAV_3421|M.avium_104 --------------FVGYDHSEVSGN--VVTVFLDRPNTNFYKVLSYSR- MAB_0426|M.abscessus_ATCC_1997 FDDLQGDPAHKIAPRATQMRGLHVVDDVTFTVRLNTPFAIYPMTLGY--- : : . * . :. Mflv_2761|M.gilvum_PYR-GCK -FKGMAIVSRANVESGRIATHPVGTGPFSFLGQ-KSGDSISLRANPDYWA Mvan_3773|M.vanbaalenii_PYR-1 -FKGMAIVSRANVESGRIATQPVGTGPFRFLGQ-KSGDSISLAANPNYWD TH_4152|M.thermoresistible__bu -FKGMAIVQRANVETGRIATHPVGTGPFEFRGA-RSGDSITLVANDDHWA MMAR_4139|M.marinum_M LLPSSMTATPEAFNKGQLAGPGPSAGPFIVTSLDRSAQRIVLTRNPKWWG MUL_4002|M.ulcerans_Agy99 LLPSSMTATPEAFNKGQLTGPGPSAGPFIVTSLDRSAQRIVLIRNPKWWG Mb1311c|M.bovis_AF2122/97 LLPASMTATPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWG Rv1280c|M.tuberculosis_H37Rv LLPASMTATPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWG MLBr_01121|M.leprae_Br4923 LLPATMTATPEAFNKGQLDRPGPSAGPFIVSSLDRTTQRIVLTHNPKWWG MSMEG_4101|M.smegmatis_MC2_155 SSILGKSTLEKDLNGQSDLRNWVGTGPFVVESVEGTTGVTLKRRDDYDWA MAV_3421|M.avium_104 AGIRAPATLALDYQRQAKVENVIGSGPFVYQSQIPDQQVVLTRRPDYAWP MAB_0426|M.abscessus_ATCC_1997 -TAFLPLPKAFFRDPVKFGVHPIGNGPFKADGDWVRGVGFTLSRYDQYAG : . *** . Mflv_2761|M.gilvum_PYR-GCK -------GPPGVAGVTFRFIPEPSTALSALQAGEVDWTDSVPPQRVSQLR Mvan_3773|M.vanbaalenii_PYR-1 -------GPPGVSGVTYRFISEPSTALSALQAGEIDWTDSVPPQRVTQLR TH_4152|M.thermoresistible__bu -------GPPRLNGVTFRFISEPATALSALQAGEIDWTDAIPTQRVTQLR MMAR_4139|M.marinum_M -------KKPRLDSITY-LVLDDAARIPALQNFTIDATGIGSLDQLTIAE MUL_4002|M.ulcerans_Agy99 -------KKPRLHSITY-LVLDDAARIPALQNFTIDATGIGSLDQLTIAE Mb1311c|M.bovis_AF2122/97 -------ARPRLDSITY-LVLDDAARLPALQNNTIDATGVGTLDQLTIAA Rv1280c|M.tuberculosis_H37Rv -------ARPRLDSITY-LVLDDAARLPALQNNTIDATGVGTLDQLTIAA MLBr_01121|M.leprae_Br4923 -------TPPRLDSITY-LVLDDAARLPALQNNTIDATGVGTLDQLTTAQ MSMEG_4101|M.smegmatis_MC2_155 PEGSKHSGKAYLERIVFKTVPEAGTRVGALQSGEAQIARNIAPYDEETVA MAV_3421|M.avium_104 PSSWPNQGPAYVDKVVFRVIGEPGLRAGAVQSHQVDVARGIQPTDEPALK MAB_0426|M.abscessus_ATCC_1997 ------EKKAKAKGLIWRVYTEGLTAYTDMQAGALDIQLDLPDAAYENAK . : : : :* : Mflv_2761|M.gilvum_PYR-GCK DDESLQLTVTPSNDYWYLALN-QAR-APWNDVRVRQAIAYAIDRDAIVQA Mvan_3773|M.vanbaalenii_PYR-1 DDESLELAVTPSNDYWYLALN-EAR-EPWNDVRVRQAVAYAVDRDAIVQA TH_4152|M.thermoresistible__bu NDDSLTLAVTPSNDYWYLALN-HAR-APWHDLRVRRAIAFGIDREAIVTA MMAR_4139|M.marinum_M RTKGISIRRAPAPSWSHFTLN-GAPGAVLADPALRLAVCKGIDRRTIAKV MUL_4002|M.ulcerans_Agy99 RTKGISIRRAPAPSWSHFTLN-GAPGAVLADPALRLAVCKGIDRRTIAKV Mb1311c|M.bovis_AF2122/97 RTKGISIRRAPGPSWYHFTLN-GAPGSILADKALRLAIAKGIDRYTIARV Rv1280c|M.tuberculosis_H37Rv RTKGISIRRAPGPSWYHFTLN-GAPGSILADKALRLAIAKGIDRYTIARV MLBr_01121|M.leprae_Br4923 RTNGISIRRTPAPRWSHFTFN-GAVGSILADQGLRLAVSKGIDRRTIAKV MSMEG_4101|M.smegmatis_MC2_155 AGGGTLLAIPVQGETNDLTVRLDNPNSPLQDKQVRLALQAATDRQAINQA MAV_3421|M.avium_104 QGGLQVIPVAAPAETANLVGF-RINNQVVDDVRVRRALQLGIDRRAVVDT MAB_0426|M.abscessus_ATCC_1997 AEFGSAYLERPRPDITSLGFP--MYDPRYRDVRVRQAISMAIDREAITQV : * :* *: . ** :: . Mflv_2761|M.gilvum_PYR-GCK TSYGTAAANQLAIPEGNPWFTPYDRYREDGEEGLETARDLLRQANAT--- Mvan_3773|M.vanbaalenii_PYR-1 TSYGTAAVNQLAIPQGNPWFTPYDRYRDDGEQGLETARTLLREAGAQ--- TH_4152|M.thermoresistible__bu TGYGTATANQLAIPPGDFWYTHYDRYRYD----LDRARALLDEARAAGVD MMAR_4139|M.marinum_M ALYG--LTNDPAPLNNHVFVAGQEGYQDNS--SPYDPEQAKRELDALGWK MUL_4002|M.ulcerans_Agy99 ALYG--LTNDPAPLNNHVFVAGQEGYQDNS--SPYDPEQAKRELDALGWK Mb1311c|M.bovis_AF2122/97 AQYG--LTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQAKRELDALGWR Rv1280c|M.tuberculosis_H37Rv AQYG--LTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQAKRELDALGWR MLBr_01121|M.leprae_Br4923 VQYG--LANNPEPLNNHVYVDGQEGYQDNSGVVGYDPEQAQHELDALGWK MSMEG_4101|M.smegmatis_MC2_155 VLSPNYPIPSGALVKGTPLRGDSSRYLQHD---LEKAKSLLDAAGWKPGP MAV_3421|M.avium_104 VLSDSYRAADSVLGHDDPLFADVSADIGYQ---PQRAAGLLDAAGWKPGG MAB_0426|M.abscessus_ATCC_1997 IFSG-TRTPATSYGSAVVYGYRKGACGKLCELHVDEANKLLDEAHFDRNK . Mflv_2761|M.gilvum_PYR-GCK -PGDLD---------MLVTTEYPETVTAAQIVADNLAP-LGITVNIRTVD Mvan_3773|M.vanbaalenii_PYR-1 -PRELD---------MLVTTEYPETVTAAQIIADNLAP-LGISVKIRTVD TH_4152|M.thermoresistible__bu PPRRLD---------MLVTGDYPQTVTAAQIIADNVAP-LGITVDIRTVD MMAR_4139|M.marinum_M LNGKFREKDGHQLVVRLLFYEAQSSRQFAQVAQYSLAQ-IGVKLELQSRS MUL_4002|M.ulcerans_Agy99 LNGKFREKDGHQLVVRLLFYEAQSSRQFAQVAQYSLAQ-IGVKLELQSRS Mb1311c|M.bovis_AF2122/97 RSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQ-IGVKLELQAKS Rv1280c|M.tuberculosis_H37Rv RSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQ-IGVKLELQAKS MLBr_01121|M.leprae_Br4923 LNGQFREKDGRQLVIRYLFYDAQGSREFAQLAQHSLAQ-IGVKLELQAKA MSMEG_4101|M.smegmatis_MC2_155 DGIRVKDGK-RLSIHQRVAPYYQVSQSVLEVLQSQWRE-AGVEIKLTSPS MAV_3421|M.avium_104 DGVREKDGK-KLVLTLAASNQSVVFRPAFEFIEQQWRE-LGVVLQNRAGD MAB_0426|M.abscessus_ATCC_1997 ------------PIELWYSSSSTGALSWVQAIGNQLQSNLKVPYLLKSLP : : : Mflv_2761|M.gilvum_PYR-GCK FATWLDE-QNSGNFDMLMMGWLGNID-----PDDFYYAQHHTDGTSNAQK Mvan_3773|M.vanbaalenii_PYR-1 FATWLDE-QNSGNFDMLMMGWLGNID-----PDDFYYAQHHTDGTSNAQK TH_4152|M.thermoresistible__bu FATWLDE-QNNGTFDMLMMGWLGNID-----PDDYYYAQHHTDGASNAQR MMAR_4139|M.marinum_M GSGFFSNYVNVGAFDIALFGWVGDAF-----PLSSLTQIYMSDGESNFGK MUL_4002|M.ulcerans_Agy99 GSGFFSNYVNVGAFDIALFGWVGDAF-----PLSSLTQIYMSDGESNFGK Mb1311c|M.bovis_AF2122/97 GSGFFSDYVNVGAFDIAQFGWVGDAF-----PLSSLTQIYASDGESNFGK Rv1280c|M.tuberculosis_H37Rv GSGFFSDYVNVGAFDIAQFGWVGDAF-----PLSSLTQIYASDGESNFGK MLBr_01121|M.leprae_Br4923 GSGFFTNYVNVGAFDIVQFGWVGDAF-----PLSALTQIYQSDGESNFGK MSMEG_4101|M.smegmatis_MC2_155 LTEYEAQ-EQSATDWFLTQGQTSTAE-----PSVLRTSYGSNRQNVTEKS MAV_3421|M.avium_104 TTFFNASSSQSS------TPLFGTRI-----QYNIGLGLLFGRPKSNLTF MAB_0426|M.abscessus_ATCC_1997 WSQFLPLQDGKGMTGPFRSGWVMDYPSIYNFLESLYGTVALPPNGSNYVF : : . . Mflv_2761|M.gilvum_PYR-GCK FSNPEVDRLLDAGRVETDEQTRKAGYARAATLIADEVSYIYLYNPSVIQA Mvan_3773|M.vanbaalenii_PYR-1 FSDPEVDRLLDASRVETDEAARKEQYAGAATLIADKVSYIYLYNPSVIQA TH_4152|M.thermoresistible__bu FSDPEVDRLLDAARAEPDRDRRKALYDRAATLIADRVSYLFLYNPAVVQA MMAR_4139|M.marinum_M IGSPQIDAAIERTLQELDPAKALALANEVDKLIWAEGFSLPLTQSPGTIA MUL_4002|M.ulcerans_Agy99 IGSPQIDAAIERTLQELDPAKALALANQVDKLIWAEGFSLPLTQSPGTIA Mb1311c|M.bovis_AF2122/97 IGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQSPGTVA Rv1280c|M.tuberculosis_H37Rv IGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQSPGTVA MLBr_01121|M.leprae_Br4923 ISSPAVDAAIERTLAELDPAKARALANEVDKLLWAEGFSLPLTQSPGDVA MSMEG_4101|M.smegmatis_MC2_155 PPDAKLDELLVAQSYEFDPEKRKAAIQAIEDHIFSEGYSIPLYDETQVFG MAV_3421|M.avium_104 AQNDALLALSEEELRQTDPTRLKDVVAREQRRIIDDQLALVLWDEVQVHA MAB_0426|M.abscessus_ATCC_1997 YSNPAFDELLRQGNNEPTVELATKAYQKAEDLLFKDLPAAPLFYEVNQAV . . : : * Mflv_2761|M.gilvum_PYR-GCK WNPALSGYEARRDGAVRFRSASLDSDGNV----- Mvan_3773|M.vanbaalenii_PYR-1 WNPALSGYEARRDGAVRFRSATFGADGGA----- TH_4152|M.thermoresistible__bu WSPDLSGYRARRDAAVRFRDASLNRDGLNRDGPP MMAR_4139|M.marinum_M VRSTLANFGARGLADLDYTAIGFMRS-------- MUL_4002|M.ulcerans_Agy99 VRSTLANFGARGLADLDYTAIGFMRS-------- Mb1311c|M.bovis_AF2122/97 VRSTLANFGATGLADLDYTAIGFMRR-------- Rv1280c|M.tuberculosis_H37Rv VRSTLANFGATGLADLDYTAIGFMRR-------- MLBr_01121|M.leprae_Br4923 VRSTLANFGAAGFGDLNYTAIGFMQN-------- MSMEG_4101|M.smegmatis_MC2_155 LGPTVQGFTTESTGRSWFYDTWLNG--------- MAV_3421|M.avium_104 AAPNVH-VEFTRYTEPLLQSAWKA---------- MAB_0426|M.abscessus_ATCC_1997 HSKRVRNVKIGIQDCIEYADVEVVQ--------- :