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RRLHKMIAGTLAVAVLAACSGQQQSASSGPSGQPQPGGTLTFSDVQFVTDALSTNYTTANLLFQVVDRLV YLDPKTGEVYGWLAEEFSRNDDATRYTFTIRDDVTFSDGTPLTAEVVKANFDQLGKGDPAKKIPPFSDFV GYDHSEVNGNTITVFLDQPNSNFYRVVANGRAGIRGEKTLALDFDGQAKIENVVGSGPFVYQSHVPDQEV VLTKRPDYAWPPVNSPNQGAAYLDKLVVRVIGEPGLRAGAVQSGQVDLARGIQPTDEPALAQGGFQVIPV AAPILTANIVGFRINNELVSDQRVRRALQLGIDRQAVVDTVLSPSYRAADSVLGHDDPLFTDESADLGYD PRRAAALLDEAGWKVGGDGIREKDGKKLNLTLAASNQSVVFRPAFEFIESGWRELGVALQNRAGDTTLFN AANADGSTPLLGTRTSYNNGLGMLFGRANGNLTFATNDELIALSAEELRATDPAHAKDIAARIQKKVIDD QLALILWDEVQVHAAAPNVHVEFTNYTEPLFQSAWKN*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_2847 | - | - | 100% (528) | extracellular solute-binding protein, family protein 5 |
M. smegmatis MC2 155 | MSMEG_4101 | - | 7e-82 | 36.81% (546) | ABC-type transporter, substrate binding protein |
M. smegmatis MC2 155 | MSMEG_4385 | - | 1e-37 | 26.59% (549) | ABC transporter oligopeptide binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1311c | oppA | 7e-09 | 23.21% (293) | periplasmic oligopeptide-binding lipoprotein OppA |
M. gilvum PYR-GCK | Mflv_0119 | - | 3e-16 | 27.79% (349) | extracellular solute-binding protein |
M. tuberculosis H37Rv | Rv1280c | oppA | 7e-09 | 23.21% (293) | periplasmic oligopeptide-binding lipoprotein OppA |
M. leprae Br4923 | MLBr_01121 | - | 3e-12 | 23.73% (413) | putative extracellular solute-binding dependent transport |
M. abscessus ATCC 19977 | MAB_0426 | - | 2e-05 | 24.92% (305) | peptide ABC transporter DppA |
M. marinum M | MMAR_4139 | oppA | 2e-08 | 23.28% (421) | periplasmic oligopeptide-binding lipoprotein OppA |
M. avium 104 | MAV_3421 | - | 0.0 | 75.10% (518) | extracellular solute-binding protein, family protein 5 |
M. thermoresistible (build 8) | TH_2965 | - | 2e-21 | 26.82% (384) | PUTATIVE extracellular solute-binding protein, family 5 |
M. ulcerans Agy99 | MUL_4002 | oppA | 2e-07 | 22.41% (424) | periplasmic oligopeptide-binding lipoprotein OppA |
M. vanbaalenii PYR-1 | Mvan_3773 | - | 3e-14 | 23.58% (369) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb1311c|M.bovis_AF2122/97 MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLT Rv1280c|M.tuberculosis_H37Rv MADRGQRRGCAPGIASALRASFQGKSRPWTQTRYWAFALLTPLVVAMVLT MMAR_4139|M.marinum_M MLTNADR---HDGVQPGPGARSRRPTRPWAR-RRIRCAGAALLTVTLLLA MUL_4002|M.ulcerans_Agy99 -----------------------------------------MLTVTLLLA MLBr_01121|M.leprae_Br4923 -------------------------------MIMLSRIVAALLVVGLILT MSMEG_2847|M.smegmatis_MC2_155 ------------------------------MRRLHKMIA--GTLAVAVLA MAV_3421|M.avium_104 ------------------------------MAKVASRTATLGAMLCVLAA Mflv_0119|M.gilvum_PYR-GCK ------------------------------MCSDRHMNFRVATVLASVLV TH_2965|M.thermoresistible__bu ------------------------------------MRIWALPVAAAALL Mvan_3773|M.vanbaalenii_PYR-1 ----------------------------------MRTVVLATCVFLAALT MAB_0426|M.abscessus_ATCC_1997 ----------------------------------MRLRRLAIVLLVGIVA Mb1311c|M.bovis_AF2122/97 GCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPP Rv1280c|M.tuberculosis_H37Rv GCSASGTQLELAPTADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPP MMAR_4139|M.marinum_M GCSAS-TQLPAATSGS--TAVGSSSDINPQDPATLEDGGDLRLSLTDFPP MUL_4002|M.ulcerans_Agy99 GCSAS-TQLPAATSGS--TAVGSSSDINPQDPATLEDGGDLRLSLTDFPP MLBr_01121|M.leprae_Br4923 GCSAS-NRLVPSAASN--AALGKTSDINPQDPATLKDGGNLRLALTDFPA MSMEG_2847|M.smegmatis_MC2_155 ACSGQQQSASSGPSGQ--PQPGGTLTFSDVQFVTDALSTNYTTANLLFQV MAV_3421|M.avium_104 GCSGHRHTASTGPTGP--PVRGGTLTYSDVQFVTDTMAANYSANNLMFQL Mflv_0119|M.gilvum_PYR-GCK AVTACSSSSPAEPRDQ--IVLAEGYELGGFNPVNGYAESGVSP--IYDGL TH_2965|M.thermoresistible__bu LIAGCTAAP--EHEGQ--IVLAEAQELGGYNPVSGYGEAGVSP--LYEAL Mvan_3773|M.vanbaalenii_PYR-1 GCSPGDRVDLGAGAAD----ALIAAIAGEPDQLDPHKTTSYFSFEVLENV MAB_0426|M.abscessus_ATCC_1997 VLPAGCGDLVTPAPPG----YFSMYITEPEHTLVPGNTTENQGGRILRSL . . Mb1311c|M.bovis_AF2122/97 NFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTA Rv1280c|M.tuberculosis_H37Rv NFNILHIDGNNAEVAAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTA MMAR_4139|M.marinum_M NFNILHIDGNSAEVAAMVKATLPRAFIIGPDGSTTVDHDYFTSVELTKTN MUL_4002|M.ulcerans_Agy99 NFNILHIDGNSAEVAAMVKATLPRAFIIGPDGSTTVDHDYFTSVELTKTN MLBr_01121|M.leprae_Br4923 NFNILHIDGNNAEVTSMMKATMPRAFIIGTDGSTTVDTNYFTSIKLTSTS MSMEG_2847|M.smegmatis_MC2_155 VDRLVYLDPKTGEVYGWLAEEFS-----------------------RNDD MAV_3421|M.avium_104 LDRVVYVDPKTDAVRGWLAKTFS-----------------------RNQN Mflv_0119|M.gilvum_PYR-GCK YRPSATTDAVIPELVPALAAQEP-----------------------QPAG TH_2965|M.thermoresistible__bu FRPEADSDDTVPDLVPALAAGEP-----------------------EQLG Mvan_3773|M.vanbaalenii_PYR-1 FDTLVEPDGNLQMQPALARAWEVS------------------------PD MAB_0426|M.abscessus_ATCC_1997 FTALVEFNNETAAVEYTGVAESIT-----------------------SHD : Mb1311c|M.bovis_AF2122/97 PQVVTYTINPEAVWSDGTPITWRDIASQIHAISGADKAFEIASSSG---- Rv1280c|M.tuberculosis_H37Rv PQVVTYTINPEAVWSDGTPITWRDIASQIHAISGADKAFEIASSSG---- MMAR_4139|M.marinum_M PQVITYTINPKAFWSDGTPITWRDIASQIHATSGADNRFEIASSGG---- MUL_4002|M.ulcerans_Agy99 PQVITYTINPKAFWSDGTPVTWRDIASQIHATSGADNRFEIASSGG---- MLBr_01121|M.leprae_Br4923 PQVVTYTINPKAVWSDGTPITWRDIDRQIHANSGKNKAFEIAGTNG---- MSMEG_2847|M.smegmatis_MC2_155 ATRYTFTIRDDVTFSDGTPLTAEVVKANFDQLGKGDPAKKIPPF------ MAV_3421|M.avium_104 ATRYTFTIRDGVSFSDHTPLTAEVVKANFDQLGKGDPAKKMPAF------ Mflv_0119|M.gilvum_PYR-GCK PNRWRVPLRPGVVFSDGTTFDPVDVVATYDAVRDPRVASEISTS------ TH_2965|M.thermoresistible__bu PRRWRIPLRTDVVFSDGTPFDAADVVATYTAVRNPEVASDIATH------ Mvan_3773|M.vanbaalenii_PYR-1 QLTWTFHLRPGVTFHDGTPLTADDVVFSYRRIIDEQLANSDKFS------ MAB_0426|M.abscessus_ATCC_1997 NVNWTIKLKPGWTFHNGEPVTAQSYVDAWNYTALSTNAQGSSSFLANVDG :. : : .. Mb1311c|M.bovis_AF2122/97 -----------AERVASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGMLLP Rv1280c|M.tuberculosis_H37Rv -----------AERVASVTRGVDDRQAVVTFAKPYAEWRGMFAGNGMLLP MMAR_4139|M.marinum_M -----------SDRVASVTPGVDDRQAIVTFAKPYAEWRGMFAGNGMLLP MUL_4002|M.ulcerans_Agy99 -----------SDRVASVIPGVDDRQAMVTFAKPYAEWRGMFAGNGMLLP MLBr_01121|M.leprae_Br4923 -----------CERVASIRPGANDRQAIVTFAQPYAEWRGMFAGNGMLLP MSMEG_2847|M.smegmatis_MC2_155 -----------SDFVGYDHSEVNGNTITVFLDQPNSNFYRVVANGRAGIR MAV_3421|M.avium_104 -----------ADFVGYDHSEVSGNVVTVFLDRPNTNFYKVLSYSRAGIR Mflv_0119|M.gilvum_PYR-GCK -----------VAPIVSIEADGPDAVVVELDTAADPKPYLLLGILPS-ER TH_2965|M.thermoresistible__bu -----------VAPVAQVRADGEDAVVVDMHTDADPKPYLLVGIAPA-ER Mvan_3773|M.vanbaalenii_PYR-1 -------------SVAAVDAP-DPNTVVIRVDRPTPN---MLTNLGGFKG MAB_0426|M.abscessus_ATCC_1997 FDDLQGDPAHKIAPRATQMRGLHVVDDVTFTVRLNTPFAIYPMTLGYTAF . Mb1311c|M.bovis_AF2122/97 ASMTATPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWG--- Rv1280c|M.tuberculosis_H37Rv ASMTATPEAFNKGQLDGPGPSAGPFVVSALDRTAQRIVLTRNPRWWG--- MMAR_4139|M.marinum_M SSMTATPEAFNKGQLAGPGPSAGPFIVTSLDRSAQRIVLTRNPKWWG--- MUL_4002|M.ulcerans_Agy99 SSMTATPEAFNKGQLTGPGPSAGPFIVTSLDRSAQRIVLIRNPKWWG--- MLBr_01121|M.leprae_Br4923 ATMTATPEAFNKGQLDRPGPSAGPFIVSSLDRTTQRIVLTHNPKWWG--- MSMEG_2847|M.smegmatis_MC2_155 GEKTLALDFDGQAKIENVVG-SGPFVYQSHVPDQEVVLTKRPDYAWPPVN MAV_3421|M.avium_104 APATLALDYQRQAKVENVIG-SGPFVYQSQIPDQQVVLTRRPDYAWPPSS Mflv_0119|M.gilvum_PYR-GCK VEATPAADWAVN---TAPVG-TGPYRLDSLRPDQAVLVAR--DDYWG--- TH_2965|M.thermoresistible__bu VESKPAANWKLN---TEPVG-TGPYRLESLRPDQAVLVAR--DDYWG--- Mvan_3773|M.vanbaalenii_PYR-1 MAIVSRANVESGRIATQPVG-TGPFRFLGQ-KSGDSISLAANPNYWD--- MAB_0426|M.abscessus_ATCC_1997 LPLPKAFFRDPVKFGVHPIG-NGPFKADGDWVRGVGFTLSRYDQYAG--- **: . . Mb1311c|M.bovis_AF2122/97 ----ARPRLDSITYLVLDD-AARLPALQNNTIDATG-VGTLDQLTIAART Rv1280c|M.tuberculosis_H37Rv ----ARPRLDSITYLVLDD-AARLPALQNNTIDATG-VGTLDQLTIAART MMAR_4139|M.marinum_M ----KKPRLDSITYLVLDD-AARIPALQNFTIDATG-IGSLDQLTIAERT MUL_4002|M.ulcerans_Agy99 ----KKPRLHSITYLVLDD-AARIPALQNFTIDATG-IGSLDQLTIAERT MLBr_01121|M.leprae_Br4923 ----TPPRLDSITYLVLDD-AARLPALQNNTIDATG-VGTLDQLTTAQRT MSMEG_2847|M.smegmatis_MC2_155 SPNQGAAYLDKLVVRVIGEPGLRAGAVQSGQVDLARGIQPTDEPALAQGG MAV_3421|M.avium_104 WPNQGPAYVDKVVFRVIGEPGLRAGAVQSHQVDVARGIQPTDEPALKQGG Mflv_0119|M.gilvum_PYR-GCK ----DAPQVRRLVYTYAPDDNARAQSMVSGAVDGTN-LPPRLIDSVKGSN TH_2965|M.thermoresistible__bu ----EPAQVRRIVYTHTPDDNVRAQRILAGEVDGVS-LPPKLISSID--R Mvan_3773|M.vanbaalenii_PYR-1 ----GPPGVSGVTYRFISEPSTALSALQAGEIDWTDSVPPQRVTQLRD-D MAB_0426|M.abscessus_ATCC_1997 ---EKKAKAKGLIWRVYTEGLTAYTDMQAGALDIQLDLPDAAYENAKAEF . : : : :* : Mb1311c|M.bovis_AF2122/97 KGISIRRAPGPSWYHFTLNGAPGSILADKALRLAIAKGIDRYTIARVAQY Rv1280c|M.tuberculosis_H37Rv KGISIRRAPGPSWYHFTLNGAPGSILADKALRLAIAKGIDRYTIARVAQY MMAR_4139|M.marinum_M KGISIRRAPAPSWSHFTLNGAPGAVLADPALRLAVCKGIDRRTIAKVALY MUL_4002|M.ulcerans_Agy99 KGISIRRAPAPSWSHFTLNGAPGAVLADPALRLAVCKGIDRRTIAKVALY MLBr_01121|M.leprae_Br4923 NGISIRRTPAPRWSHFTFNGAVGSILADQGLRLAVSKGIDRRTIAKVVQY MSMEG_2847|M.smegmatis_MC2_155 FQVIPVAAPILTANIVGFR-INNELVSDQRVRRALQLGIDRQAVVDTVLS MAV_3421|M.avium_104 LQVIPVAAPAETANLVGFR-INNQVVDDVRVRRALQLGIDRRAVVDTVLS Mflv_0119|M.gilvum_PYR-GCK DDVQTVAVRSADWRGIALP-ADNPFTADVTARLAMNVGIDRDALVRDVLV TH_2965|M.thermoresistible__bu DDIDAIAVQSADWRGVALP-ARNAFTADPRARLAMNLAVDRDAIIRDVLD Mvan_3773|M.vanbaalenii_PYR-1 ESLELAVTPSNDYWYLALNEAREPWN-DVRVRQAVAYAVDRDAIVQATSY MAB_0426|M.abscessus_ATCC_1997 GSAYLE-RPRPDITSLGFP-MYDPRYRDVRVRQAISMAIDREAITQVIFS . : * * *: .:** :: Mb1311c|M.bovis_AF2122/97 GLTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQAKRELDALGWRRSG-A Rv1280c|M.tuberculosis_H37Rv GLTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQAKRELDALGWRRSG-A MMAR_4139|M.marinum_M GLTNDPAPLNNHVFVAGQEGYQDNS--SPYDPEQAKRELDALGWKLNG-K MUL_4002|M.ulcerans_Agy99 GLTNDPAPLNNHVFVAGQEGYQDNS--SPYDPEQAKRELDALGWKLNG-K MLBr_01121|M.leprae_Br4923 GLANNPEPLNNHVYVDGQEGYQDNSGVVGYDPEQAQHELDALGWKLNG-Q MSMEG_2847|M.smegmatis_MC2_155 PSYRAADSVLGHDDP----LFTDESADLGYDPRRAAALLDEAGWKVGGDG MAV_3421|M.avium_104 DSYRAADSVLGHDDP----LFADVSADIGYQPQRAAGLLDAAGWKPGGDG Mflv_0119|M.gilvum_PYR-GCK GYGSPAATPVADAYG----DAYDPGAQYVFDLDRARNLLDDAGWRPGAGQ TH_2965|M.thermoresistible__bu GYGRPAGTPIATVYG----PAYHPDAQFDHAPERAATVLDTAGWRVGPDG Mvan_3773|M.vanbaalenii_PYR-1 GTAAVNQLAIPQGNP-------------WFTPYDRYRDDGEQGLETARTL MAB_0426|M.abscessus_ATCC_1997 GTRTPATSYGSAVVY-------------GYRKGACGKLCELHVDEANKLL . . Mb1311c|M.bovis_AF2122/97 FREKDGRQLVIRDLFYDAQST-RQFAQIAQHTLAQ-IGVKLELQAKSGSG Rv1280c|M.tuberculosis_H37Rv FREKDGRQLVIRDLFYDAQST-RQFAQIAQHTLAQ-IGVKLELQAKSGSG MMAR_4139|M.marinum_M FREKDGHQLVVRLLFYEAQSS-RQFAQVAQYSLAQ-IGVKLELQSRSGSG MUL_4002|M.ulcerans_Agy99 FREKDGHQLVVRLLFYEAQSS-RQFAQVAQYSLAQ-IGVKLELQSRSGSG MLBr_01121|M.leprae_Br4923 FREKDGRQLVIRYLFYDAQGS-REFAQLAQHSLAQ-IGVKLELQAKAGSG MSMEG_2847|M.smegmatis_MC2_155 IREKDGKKLNLTLAASNQSVVFRPAFEFIESGWRE-LGVALQNRAGDTTL MAV_3421|M.avium_104 VREKDGKKLVLTLAASNQSVVFRPAFEFIEQQWRE-LGVVLQNRAGDTTF Mflv_0119|M.gilvum_PYR-GCK IREKDGARASFELLYNAQDTLRRDLAVAYAAAMKP-LGVDVRPRGTSWDE TH_2965|M.thermoresistible__bu IREKDGARASFELLYNAADTLRRDLAVAFATAMRP-LGIDVRTRGTSWDE Mvan_3773|M.vanbaalenii_PYR-1 LREAGAQPRELDMLVTTEYPETVTAAQIIADNLAP-LGISVKIRTVDFAT MAB_0426|M.abscessus_ATCC_1997 DEAHFDRNKPIELWYSSSSTGALSWVQAIGNQLQSNLKVPYLLKSLPWSQ . . : : : Mb1311c|M.bovis_AF2122/97 FFSDYVN--VGAFDIAQFGWVGDA-----FPLSSLTQIYASDGESNFGKI Rv1280c|M.tuberculosis_H37Rv FFSDYVN--VGAFDIAQFGWVGDA-----FPLSSLTQIYASDGESNFGKI MMAR_4139|M.marinum_M FFSNYVN--VGAFDIALFGWVGDA-----FPLSSLTQIYMSDGESNFGKI MUL_4002|M.ulcerans_Agy99 FFSNYVN--VGAFDIALFGWVGDA-----FPLSSLTQIYMSDGESNFGKI MLBr_01121|M.leprae_Br4923 FFTNYVN--VGAFDIVQFGWVGDA-----FPLSALTQIYQSDGESNFGKI MSMEG_2847|M.smegmatis_MC2_155 FNAANADGSTPLLGTRTSYNNG--------LGMLFGRANGNLTFATNDEL MAV_3421|M.avium_104 FNASSSQSSTPLFGTRIQYNIG--------LGLLFGRPKSNLTFAQNDAL Mflv_0119|M.gilvum_PYR-GCK IDTRFADSAVVLGGGATPYSIDSQ-----VYDTLHTRVPDSSPYSNPGNF TH_2965|M.thermoresistible__bu IETRTADSAILLGGGSTPYSIDAQ-----VYDTLHTRVPGSSPYANPGNF Mvan_3773|M.vanbaalenii_PYR-1 WLDEQNS---GNFDMLMMGWLGNI-----DPDDFYYAQHHTDGTSNAQKF MAB_0426|M.abscessus_ATCC_1997 FLPLQDG--KGMTGPFRSGWVMDYPSIYNFLESLYGTVALPPNGSNYVFY . : Mb1311c|M.bovis_AF2122/97 GSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQSPGTVAV Rv1280c|M.tuberculosis_H37Rv GSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQSPGTVAV MMAR_4139|M.marinum_M GSPQIDAAIERTLQELDPAKALALANEVDKLIWAEGFSLPLTQSPGTIAV MUL_4002|M.ulcerans_Agy99 GSPQIDAAIERTLQELDPAKALALANQVDKLIWAEGFSLPLTQSPGTIAV MLBr_01121|M.leprae_Br4923 SSPAVDAAIERTLAELDPAKARALANEVDKLLWAEGFSLPLTQSPGDVAV MSMEG_2847|M.smegmatis_MC2_155 IALSAEELRATDPAHAKDIAARIQKKVIDDQLALILWDEVQVHAAAPN-- MAV_3421|M.avium_104 LALSEEELRQTDPTRLKDVVAREQRRIIDDQLALVLWDEVQVHAAAPN-- Mflv_0119|M.gilvum_PYR-GCK TAPGLDALLEQAAQSPSGPAKDALYREIQARYAAAPSHVFLVFLHHTYSY TH_2965|M.thermoresistible__bu TAPGLDELLDRARELPGGPEKDDLYRRIQEVYAAEPSHVFLVFLDHTYGS Mvan_3773|M.vanbaalenii_PYR-1 SDPEVDRLLDASRVETDEAARKEQYAGAATLIADKVSYIYLYNPSVIQAW MAB_0426|M.abscessus_ATCC_1997 SNPAFDELLRQGNNEPTVELATKAYQKAEDLLFKDLPAAPLFYEVNQAVH : Mb1311c|M.bovis_AF2122/97 R-------STLANFGATGLADLDYTAIGFMRR--- Rv1280c|M.tuberculosis_H37Rv R-------STLANFGATGLADLDYTAIGFMRR--- MMAR_4139|M.marinum_M R-------STLANFGARGLADLDYTAIGFMRS--- MUL_4002|M.ulcerans_Agy99 R-------STLANFGARGLADLDYTAIGFMRS--- MLBr_01121|M.leprae_Br4923 R-------STLANFGAAGFGDLNYTAIGFMQN--- MSMEG_2847|M.smegmatis_MC2_155 -------VHVEFTNYTEPLFQSAWKN--------- MAV_3421|M.avium_104 -------VHVEFTRYTEPLLQSAWKA--------- Mflv_0119|M.gilvum_PYR-GCK RDLGWQQSAPIMEPHSHGVSWGPWWNLAAWTR--- TH_2965|M.thermoresistible__bu RDRGWDPVQPILEPHSHGVTWGPWWRIGAWTR--- Mvan_3773|M.vanbaalenii_PYR-1 N-------PALSGYEARRDGAVRFRSATFGADGGA MAB_0426|M.abscessus_ATCC_1997 S-------KRVRNVKIGIQDCIEYADVEVVQ---- :