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SAVPVLLELAVGEAPSQVSLAEADAIAATAQDLGVTAVRLVDRVGEQPAIDPSMVAAHLAGRYPDLGWLI DAPTTHNAPYNLARRILSVDRATGGRAGLVLIPGGGDEVSDAAVPDCAATDPAERWAEYADIVTRLWESF PAAALLGDQQRAVVVDDVLIRPVDFRGRFYRVGGPLDGPSSLQGRPMLVAAAPTEVGWARIAAIADAAIV ELNEINYATAQLRAALHATGRRREDVALLVRTTDPEIINHATADLNADGIVIAANGGAPEMLAALRRAGR QDTPQRRATLRATLTIPSPEGVST*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4095 | - | - | 100% (305) | putative monooxygenase |
| M. smegmatis MC2 155 | MSMEG_1162 | - | 1e-21 | 32.00% (200) | nitrilotriacetate monooxygenase component A |
| M. smegmatis MC2 155 | MSMEG_4091 | ssuD | 6e-21 | 31.31% (214) | nitrilotriacetate monooxygenase component A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1269 | - | 1e-10 | 25.76% (198) | putative monooxygenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4234c | - | 2e-17 | 30.11% (186) | putative FMNH2-utilizing oxygenase |
| M. marinum M | MMAR_0701 | - | 1e-12 | 26.96% (293) | oxidoreductase |
| M. avium 104 | MAV_4059 | - | 3e-16 | 29.30% (215) | monoxygenase |
| M. thermoresistible (build 8) | TH_4079 | - | 6e-20 | 31.98% (197) | PUTATIVE nitrilotriacetate monooxygenase component A |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3887 | - | 5e-15 | 27.54% (236) | putative monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4234c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0701|M.marinum_M --------------------------------------------------
TH_4079|M.thermoresistible__bu --------------------------------------------------
Mflv_1269|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4059|M.avium_104 MTLTSPAAASAGDLPARPGLRTVAAGSMIGTTIEWYDFYLYATASALVFK
MSMEG_4095|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4234c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0701|M.marinum_M --------------------------------------------------
TH_4079|M.thermoresistible__bu --------------------------------------------------
Mflv_1269|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4059|M.avium_104 PLFFPNISPSAGTLASFATYAAGFGARPLGAVLSGHFGDRLGRKTVLVAA
MSMEG_4095|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4234c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0701|M.marinum_M --------------------------------------------------
TH_4079|M.thermoresistible__bu --------------------------------------------------
Mflv_1269|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4059|M.avium_104 LLVMGLVTTAIGALPTYAEAGLAAPALLASLRVVQGLAVGAEWGGAAVLS
MSMEG_4095|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4234c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0701|M.marinum_M --------------------------------------------------
TH_4079|M.thermoresistible__bu --------------------------------------------------
Mflv_1269|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4059|M.avium_104 VEHAPPGRRGLFGSFTQLGSPAGMLLATSVFFGVRKATGPAAFLGFGWRI
MSMEG_4095|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4234c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0701|M.marinum_M --------------------------------------------------
TH_4079|M.thermoresistible__bu --------------------------------------------------
Mflv_1269|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4059|M.avium_104 PFLLSIFLVAVGLFVRLRLTDAEVFDRLRSRDELARLPIVQVLRTDARNV
MSMEG_4095|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4234c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0701|M.marinum_M --------------------------------------------------
TH_4079|M.thermoresistible__bu --------------------------------------------------
Mflv_1269|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4059|M.avium_104 VITTGLRLSQIGLFVLLTTYSLSYLQDSFGKGSGVGLVAVLISSALGFLS
MSMEG_4095|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4234c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0701|M.marinum_M --------------------------------------------------
TH_4079|M.thermoresistible__bu --------------------------------------------------
Mflv_1269|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4059|M.avium_104 TPGWALLSDRVGRRPPYLFGALASVVALVLFFVAAGTGSAVLVVVAIVFG
MSMEG_4095|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4234c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0701|M.marinum_M --------------------------------------------------
TH_4079|M.thermoresistible__bu --------------------------------------------------
Mflv_1269|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3887|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4059|M.avium_104 VNVVHDAMYGPQAAWFAELFDTRVRYSGSSLGYHIGAVLSGGFAPLIAAS
MSMEG_4095|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4234c|M.abscessus_ATCC_199 ------------------------------------MGVAPTVTTLLGLA
MMAR_0701|M.marinum_M ----------------------------------------MTRPLHLGVA
TH_4079|M.thermoresistible__bu --------------------------------------------------
Mflv_1269|M.gilvum_PYR-GCK ----------------------------------MYSIQGMTQR-MIFTL
Mvan_3887|M.vanbaalenii_PYR-1 ----------------------------------------MTKRPLYYSA
MAV_4059|M.avium_104 LLVAGGGRPWLIVGYFAVLAAITVGAACAGPGDARGADRMSAARRIYLNA
MSMEG_4095|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4234c|M.abscessus_ATCC_199 LDGHGWHP-------DADKHAGKPLTGRYWTQQVQLAEQGLLDFVTFEDS
MMAR_0701|M.marinum_M LDGYGWHPQAWQTTLAADAQTRSVLSGDYWADLAITAERGLLDFLTIDDT
TH_4079|M.thermoresistible__bu ---------------LPETRLSGITDIDHYLELARIAERGKLDAIFFADH
Mflv_1269|M.gilvum_PYR-GCK LVMDSIGHNFHGSWRHPAARNREFKGFDMWVDLARKAEQAKVDAFFFTDV
Mvan_3887|M.vanbaalenii_PYR-1 FVMNTASHVLHGLWRAPDAQNHRFNSLRHWTSLAAEVDKAGYDVLFFADV
MAV_4059|M.avium_104 FDMACVGHQSAGLWRHPDDQGHRYRELSYWTELARTLEAGGFDALFLADV
MSMEG_4095|M.smegmatis_MC2_155 ------MSAVPVLLELAVGEAPSQVSLAEADAIAATAQDLGVTAVRLVDR
. . . : . : *
MAB_4234c|M.abscessus_ATCC_199 FAPTPG---------------GRLDAVLTAGRVAPATHHIGLIPTAPATH
MMAR_0701|M.marinum_M LMPQPGRRERI----DPKRLAGRADAVLVAARIAPLTRHIGLIPVATVTH
TH_4079|M.thermoresistible__bu PVLKGKTEFR---------PFDALDPVTLVTALSTATTHIGLVATASTTY
Mflv_1269|M.gilvum_PYR-GCK MGVQGEYNGKRDIVFEMAMNVPIGDCTMLIPALAQQTRDLGFLYTSSVIS
Mvan_3887|M.vanbaalenii_PYR-1 FGLRAPWNGNWRKAVEGGIQVPVNDPSVLASAIAAATENLGIVFTSSIVQ
MAV_4059|M.avium_104 LGVYDIYGASRDAAVVDAAQFPVNEPSAAVSAMAAVTETLGFGITLSLTY
MSMEG_4095|M.smegmatis_MC2_155 VG-----------------EQPAIDPSMVAAHLAGRYPDLGWLIDAPTTH
: :: :* .
MAB_4234c|M.abscessus_ATCC_199 NEPFHLSKSIATLDIVSGGRAGWQVTIADTEDEADAFGRTKVLP---LQD
MMAR_0701|M.marinum_M TEPFHISKAIATLDYVSHGRAGWQARVSATTHEAALFGRRIVRRGESSAE
TH_4079|M.thermoresistible__bu TEPYGLARRFATLDHVSRGRAGWNIVTTANAAAAANFGRPAHPD---PEH
Mflv_1269|M.gilvum_PYR-GCK HHPFVFARAASTLDNLSNGRIGWNIVTSANEKAFRNLGLPGNLS---HDE
Mvan_3887|M.vanbaalenii_PYR-1 DHPFNFARRMSSLDHYTDGRLGWNIVTSFNANMFRSFGHEGTLA---HDQ
MAV_4059|M.avium_104 EQPYALARRLSTLDHLTGGRVAWNIVTSYLDSAARNLGLDAQIP---HDQ
MSMEG_4095|M.smegmatis_MC2_155 NAPYNLARRILSVDRATGGRAGLVLIPGGGDEVSDAAVPDCAAT-----D
*: ::: ::* : ** . .
MAB_4234c|M.abscessus_ATCC_199 LLDEAADSVEVVRRLWD-SWEDDAEIRDVATGRFIDRDKLHYIDFEGRFF
MMAR_0701|M.marinum_M AFGEARDFVEVVRKLWD-SWEDDAVIRDVTTGRYIDRDKVHYIDFVGTYF
TH_4079|M.thermoresistible__bu RYSRADEFLQVALRLWD-SWEDDAIVGDKQAPRFVDPDKIHAIDHRGEHF
Mflv_1269|M.gilvum_PYR-GCK RYVWAQEYVDVTYKLWEGSWDVDAIVDDPASGVYADPSKVHDINHKGARY
Mvan_3887|M.vanbaalenii_PYR-1 RYEWANEYVDVTYKLWEGSWDDDALVQDKERSVHSDPSKIHKINHVGRRY
MAV_4059|M.avium_104 RYEIADEYLEVCYKLWEGSWEAGAVLRDRQRGVFTDPAKVHDIEHKGRYF
MSMEG_4095|M.smegmatis_MC2_155 PAERWAEYADIVTRLWE-SFPAAALLGDQQRAVVVDDVLIRPVDFRGRFY
: :: :**: *: * : * * :: ::. * :
MAB_4234c|M.abscessus_ATCC_199 SVKGPSITPRSPQGQAVVAALARSRPGQAFAAKNADLIFVTPHDGASAAE
MMAR_0701|M.marinum_M SVKGPSITPRPPQGQPVVAALAHAGPIYEFAAASADVVFITPTDEDSLRS
TH_4079|M.thermoresistible__bu SVAGPLEVPRSPQGHPVLFQAGSSEPGKQLAAKYAEAIFTAQPTVEEARQ
Mflv_1269|M.gilvum_PYR-GCK SVEGFNLMEPSPQRTPVLAQAGGSPAGLAFAGKHAELMFLSAYSLETIAA
Mvan_3887|M.vanbaalenii_PYR-1 TVEGPHFTSPSPQRTPVLFQAGSSPAGQLFSARNAEGVYISSPTPADAHK
MAV_4059|M.avium_104 SVPGPFLCEPSPQRTPVLFQAGASPRGIRFAAAHAEAVFVSGPTAQVVRE
MSMEG_4095|M.smegmatis_MC2_155 RVGGPLDGPSSLQGRPMLVAAAPTEVGWARIAAIADAAIVELNEINYATA
* * . * .:: . : . *:
MAB_4234c|M.abscessus_ATCC_199 IPARLHNTAGH--------------------------RVIKVLADLVVS-
MMAR_0701|M.marinum_M ILGEVRATG----------------------------VALKVFADVVVS-
TH_4079|M.thermoresistible__bu FYADVKARVRQHGRDPDRVHILPGLSAIIGGTEEEARRIQRRLEDLTVPD
Mflv_1269|M.gilvum_PYR-GCK QVGAVREQARTNGRRDGDILFLQGMMFVIGSTDEEAYRKWGELEEWRSPE
Mvan_3887|M.vanbaalenii_PYR-1 LTGETRALAAANGRDPQDITFAQGLSFVIGDTHAEAVRRNDELKRYLDVE
MAV_4059|M.avium_104 PVRALRTAAAQLGRDPRAVKVFTMVTPVVAETHDAAVAKLAEYRRFVSPR
MSMEG_4095|M.smegmatis_MC2_155 QLRAALHATG---------------------------RRREDVALLVRT-
MAB_4234c|M.abscessus_ATCC_199 ------------------FDREDEFPSD----------------------
MMAR_0701|M.marinum_M ------------------LHDGADFRSD----------------------
TH_4079|M.thermoresistible__bu YGLEQLSRIVGYRVGRDDLDRRLQFGSDDPPAIHMQSRYALVRRLVSTEN
Mflv_1269|M.gilvum_PYR-GCK AQTAYFSSLSG----MDLGRYDPGTPLENILDEIPGIQGAFLAVINAWPD
Mvan_3887|M.vanbaalenii_PYR-1 GVALHALGDAG----IDAGNLPLDTPIS-ALGEFTGIQ-SFSRWAAEISG
MAV_4059|M.avium_104 GALALFGGWTG----VDLAELDPDEPLT--YVETDANRSALASFTTAGRA
MSMEG_4095|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4234c|M.abscessus_ATCC_199 ---------------AAVFTGRAPELAELIAQWHEWG-IDGVRLRPAANA
MMAR_0701|M.marinum_M ---------------ALVWAGSPTELVEMLLDWRRLG-IDGARLRPAVNA
TH_4079|M.thermoresistible__bu LTVRELLLRLSGGRGHRVFAGTPEQVADTIEEWFTTGAADGFNLIPPALP
Mflv_1269|M.gilvum_PYR-GCK GSKPTIKDFLTSLSLPQMVVGSPETIAGRLLEYQ-GAGVNGVQVMNALLP
Mvan_3887|M.vanbaalenii_PYR-1 NDEPTIRDMAWALEGANRVVGTPKEIADRLEEWR-EAGVDGINVYHATLP
MAV_4059|M.avium_104 WTVAELAAEIGIGGRGPVLVGSPTEVADELERWVDDADVDGFNVAYVTTP
MSMEG_4095|M.smegmatis_MC2_155 --------------------TDPEIINHATADLN----ADGIVIAANGG-
. : :* :
MAB_4234c|M.abscessus_ATCC_199 LDIPVVVDELVPLLQAHQGFRTEYENG-ALRERLGLPAAINRYARKSA--
MMAR_0701|M.marinum_M TDLAGIVDEVVPLLQRAGCFRTGYRDGETLRERLGLPPAPNRYAAVSR--
TH_4079|M.thermoresistible__bu SSLTAFVDHVVPELQRRGLFRTEYTGT-TLRDHLGLPRPRNRFTTGRPVA
Mflv_1269|M.gilvum_PYR-GCK NSYAEFFEHLVPVLQDKGIMQKEYQPGTLRQKLFGSGPDISERHPAHGYR
Mvan_3887|M.vanbaalenii_PYR-1 ASFREVADRLFPTLRERGLIGTD-KSGTLRHKLLGRGDRLPDTHPAARYR
MAV_4059|M.avium_104 GTFVDFAKFVVPELRRRGHVPEQVPGSTLRERLGAAGPLLGDDHPGAAYR
MSMEG_4095|M.smegmatis_MC2_155 ------APEMLAALRRAGRQDTPQRRATLRATLTIPSPEGVST-------
:.. *:
MAB_4234c|M.abscessus_ATCC_199 -------------------
MMAR_0701|M.marinum_M -------------------
TH_4079|M.thermoresistible__bu AAS----------------
Mflv_1269|M.gilvum_PYR-GCK GMFC---------------
Mvan_3887|M.vanbaalenii_PYR-1 GAFSDNSLADRVPETVGSV
MAV_4059|M.avium_104 LRRDR--------------
MSMEG_4095|M.smegmatis_MC2_155 -------------------