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SGPLESTLVIDMTEVMQGPLAAQVLGDYGADVIKIERSCGDIMRGLDRDAVAAGEMSSYFVAVNRNKRSI QIDLKHPEGQAILHRLLDRADVLIHSYRPAAVRRMNLSYDDLAARYPRLIYASASGWGETGPLTHKAGQD MLAQSFSGMARAVADPSALAEFNPVATTDFASGMSLAQGILAALIERGRTGRGQHVSVNLLDTAIAQQML EAASLLMYGRELNWVQQWWSGVFETADGYVTVLGFFRENAIGLACKALDVADLSQDEDFDTPAKQAANRD RAHEYLAPRVKELTTATAVQRFDSVDLLCAPLLTLEQALAEEQVKVNDRRVTVEVPHQGERAVIGHPVHL SGAAPRTRHNVPLPGQHGTEILQELGFDDGQIATLRRARVVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3981 | - | - | 100% (393) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. smegmatis MC2 155 | MSMEG_1154 | - | 3e-80 | 41.49% (388) | formyl-coenzyme A transferase |
| M. smegmatis MC2 155 | MSMEG_4120 | - | 5e-47 | 34.16% (404) | CAIB/BAIF family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 2e-36 | 28.46% (390) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_1791 | - | 3e-41 | 30.65% (385) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 4e-37 | 28.72% (390) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4651c | - | 9e-36 | 28.30% (364) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_4713 | - | 7e-41 | 32.93% (410) | dehydratase |
| M. avium 104 | MAV_4024 | - | 5e-41 | 29.31% (389) | caib/baif family protein |
| M. thermoresistible (build 8) | TH_3339 | - | 6e-41 | 28.11% (402) | PUTATIVE putative L-carnitine dehydratase/bile acid-inducible |
| M. ulcerans Agy99 | MUL_2621 | - | 1e-38 | 30.03% (393) | acyl-CoA transferase |
| M. vanbaalenii PYR-1 | Mvan_1126 | - | 6e-42 | 30.18% (381) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4651c|M.abscessus_ATCC_199 ------------MTGALDGIRVLELGTLIAGPFAGRLLGDMGAEVLKIEP
MAV_4024|M.avium_104 -------MSAAGAAGPLDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEL
TH_3339|M.thermoresistible__bu MTTEVETTATQPTTGPLHGIRVVEMGSLLAGPIVGQMMGDLGADVVKIED
Mb3300|M.bovis_AF2122/97 -------MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEA
Rv3272|M.tuberculosis_H37Rv -------MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEA
MUL_2621|M.ulcerans_Agy99 -------MPEGNPAKPLDGFRVLDFTQNVAGPLAGQVLADLGAEVIKVEA
MSMEG_3981|M.smegmatis_MC2_155 ------------MSGPLESTLVIDMTEVMQGPLAAQVLGDYGADVIKIER
MMAR_4713|M.marinum_M -------------MKPLEGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEH
Mflv_1791|M.gilvum_PYR-GCK ----------MADSGPLAGIRVVDLTAMVMGPYCTQIMADMGADVIKVEP
Mvan_1126|M.vanbaalenii_PYR-1 ----------MSSAGPLSGVNVVDLTAVVAGPYCTQIMADMGADVVKVEP
.* . *::. * :: : **:*:*:*
MAB_4651c|M.abscessus_ATCC_199 PGAPDPLRTWGQA---EVDG-HHVFWTVHARNKKAITLDLRTEAGRALFL
MAV_4024|M.avium_104 PRAPDPLRTWGQA---EVDG-HHVFWTVHARNKRAITLDLRHPRGRELFC
TH_3339|M.thermoresistible__bu PGKGDPLRQWGQN---RPKG-QSLWFSIVGRNKRSVTINLREPRGQELVR
Mb3300|M.bovis_AF2122/97 PGGEAARQITSVL---PGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQML
Rv3272|M.tuberculosis_H37Rv PGGEAARQITSVL---PGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQML
MUL_2621|M.ulcerans_Agy99 PGGEAARHITAVL---PHRPPLATYFLPNNRGKKSVSVDLSTDTARRQIL
MSMEG_3981|M.smegmatis_MC2_155 SCG-DIMRGLDRD--AVAAGEMSSYFVAVNRNKRSIQIDLKHPEGQAILH
MMAR_4713|M.marinum_M AVTGDPQRGLRQTGMLRVEGDPNPNIEHANRGKRSLGLDMSISEGKEVLH
Mflv_1791|M.gilvum_PYR-GCK PQG-DNTRYISVG----PVSGMSGVFVNVNRGKRSIVLDLRSVEGKAALR
Mvan_1126|M.vanbaalenii_PYR-1 PQG-DNARYISVG----PEPGLSGVFTNVNRGKRSAVLDLQTDEGKRALR
. : *.*:: ::: .: .
MAB_4651c|M.abscessus_ATCC_199 DLVDKSDVIVENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQTGPDA
MAV_4024|M.avium_104 ELVEKSDIVVENFRPGTLEKWNLGYDVLCERNPGIILVRVSGYGQTGPDA
TH_3339|M.thermoresistible__bu QLVAEADVLVENFRPGTMERWGLGYSDLAEINPRLVIVRVSGFGQDGPYA
Mb3300|M.bovis_AF2122/97 RLADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHG
Rv3272|M.tuberculosis_H37Rv RLADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHG
MUL_2621|M.ulcerans_Agy99 RLADTADVVLEGFRPGVMERMGLGPEDLRARNPKLIYARLSAFGGNGPHG
MSMEG_3981|M.smegmatis_MC2_155 RLLDRADVLIHSYRPAAVRRMNLSYDDLAARYPRLIYASASGWGETGPLT
MMAR_4713|M.marinum_M ELARRSDVFLTSFLPGARRKFGIDLEDIRAVNPSIIYARGSALGPRGEEA
Mflv_1791|M.gilvum_PYR-GCK ALIERADVFIHSMRSKAIAKLGFGYDDVAAVNPTIIYTNCYGYGRRGPER
Mvan_1126|M.vanbaalenii_PYR-1 ALVGQADVFIHSMRAAAIAKLGFDYQTVAALNPSIVYTNCYGYGRTGPYA
* :*:.: . . : .:. . : :: . . * *
MAB_4651c|M.abscessus_ATCC_199 HKAGYASVAEAASGLRHLNGFPGGPPPRMA---LSIGDTLAGMFAAQGAL
MAV_4024|M.avium_104 AKAGYASVAEAASGLRHLNGFPGGPPPRLA---LSLGDSLAGMFGAQGAL
TH_3339|M.thermoresistible__bu SRPGYGAIGEAMGGLRYVVGDPSTPPSRVG---ISIGDTLAALFATIGAL
Mb3300|M.bovis_AF2122/97 SRPGIDLVVAAEAGMTTGMPTPEGKPQIIP---FQLVDNASGHVLAQAVL
Rv3272|M.tuberculosis_H37Rv SRPGIDLVVAAEAGMTTGMPTPEGKPQIIP---FQLVDNASGHVLAQAVL
MUL_2621|M.ulcerans_Agy99 TRPGVDLMVAAEAGMTTGMPTPDGKPQIIP---FQLVDNASGHVLAQAVL
MSMEG_3981|M.smegmatis_MC2_155 HKAGQDMLAQSFSGMARAVADPSALAEFN---PVATTDFASGMSLAQGIL
MMAR_4713|M.marinum_M AKGGYDMTAFWCRAGTAATITPMGYQGMINPPGPAYGDTISGTNLAGGIA
Mflv_1791|M.gilvum_PYR-GCK DRPAYDDTIQAECGLPAVQKQLTGEADYVG---TIMADKVAGLTALYATM
Mvan_1126|M.vanbaalenii_PYR-1 ARPAYDDTIQAECGLAAVQEELTGTAGYVG---SIMADKVCGLSALNATM
: . . * .. .
MAB_4651c|M.abscessus_ATCC_199 AALYRRTVTGRGQVVDAALTESCLAVQESTIPDYDVGRVVRGPS------
MAV_4024|M.avium_104 AALYRRSVTGRGQVVDVALTESCLAVQESTIPDYDVGGVVRGPS------
TH_3339|M.thermoresistible__bu AALREREISGRGQMVDSAIYEAVLGVMESLVPEWTVSGYQRERT------
Mb3300|M.bovis_AF2122/97 AALLHRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPK-PEPAP
Rv3272|M.tuberculosis_H37Rv AALLHRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPK-PEPAP
MUL_2621|M.ulcerans_Agy99 AALLNRERHGVADTVRVAMYDVAVGLQANQLTMHLNRPSSDAPKRPEQTP
MSMEG_3981|M.smegmatis_MC2_155 AALIERGRTGRGQHVSVNLLDTAIAQQMLEAASLLMYGRELNWV------
MMAR_4713|M.marinum_M AALLKRERTGEPSVVDVSLLGSGLWSLGHTVALTRHLGQRLEAP------
Mflv_1791|M.gilvum_PYR-GCK MALFHRERTGEGQEVEVAMFETMASFMLVEHANGAMFDPPLGPA------
Mvan_1126|M.vanbaalenii_PYR-1 MALFHRARTGEGQEVEVPMFETMAAFMLVEHANGAMFDPPLGPA------
** .* * . * :
MAB_4651c|M.abscessus_ATCC_199 -----GTRLEGIAPSNIYQSADGS-WVVIAANQDTVFRRLCEAMGRPELS
MAV_4024|M.avium_104 -----GTRLEGIAPSNIYRSADGS-WVVIAANQDTVFARLCKAMGRAELA
TH_3339|M.thermoresistible__bu -----GAILPKIAPSNVYPTSDDT-WILIAANQDTVFRRLAEAMGRPELA
Mb3300|M.bovis_AF2122/97 KAKRRKGVGFATQPSDAFRTADG--YIVISAYVPKHWQKLCYLIGRPDLV
Rv3272|M.tuberculosis_H37Rv KAKRRKGVGFATQPSDAFRTADG--YIVISAYVPKHWQKLCYLIGRPDLV
MUL_2621|M.ulcerans_Agy99 AGARRKRVAFATQPSDAFRAADG--YLLISAYVPKHWQRLCEIIGQPDLL
MSMEG_3981|M.smegmatis_MC2_155 --QQWWSG--------VFETADG-YVTVLGFFRENAIGLACKALDVADLS
MMAR_4713|M.marinum_M --PPGIHGSPINPLVGVYATSDGRYISLVMMQPTKFWADVCRHIDRPDLA
Mflv_1791|M.gilvum_PYR-GCK --VYPRTVAPNR---RPYRTKDG--HIAALIYNDKHWNAFIAAVRPPWAS
Mvan_1126|M.vanbaalenii_PYR-1 --LYPRTVARNR---RPYPTLDG--HIAVLIYNDKQWHAFIDAVKPAWAS
: : *. . : .
MAB_4651c|M.abscessus_ATCC_199 SDARFANHVARGRNQDDLDAIIAQWAAQRLPTDIIDVLSAAGVIAGPINT
MAV_4024|M.avium_104 TDERFATHVARGRIQDELDGIIGEWAAQRQPDEIIETLSAAGVIAGPINT
TH_3339|M.thermoresistible__bu EDERYATHVARGEHQAELDEIVAEFTRRHTAAEVEALMHKHNVPVGKIYR
Mb3300|M.bovis_AF2122/97 EDQRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHT
Rv3272|M.tuberculosis_H37Rv EDQRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHT
MUL_2621|M.ulcerans_Agy99 DDERFIDQRARAINYAELTEELESALAAKTAAQWVELLHEGGLMACLAYT
MSMEG_3981|M.smegmatis_MC2_155 QDEDFDTPAKQAANRDRAHEYLAPRVKELTTATAVQRFDSVDLLCAPLLT
MMAR_4713|M.marinum_M EDPRFATVEKIAAHTADAVEILTKAISARTLAEWSERFATLAGPWAPVQD
Mflv_1791|M.gilvum_PYR-GCK --ELYSTLESRAHQIDTVYGLVAETLAERTTEEWLNLFRELEIPAAPLNT
Mvan_1126|M.vanbaalenii_PYR-1 --DRYATMAGRAADIDTVYGLVGDTLREQTTADWLALFDKLGIPASPLRT
: . : :
MAB_4651c|M.abscessus_ATCC_199 VADVVQDPQLKAREMLVEHFDERLGRSVLGPGVVPVLSESPGGVRNAGPA
MAV_4024|M.avium_104 VAEVVNDPQLRARDMLVEHYDERLRRNVLGPGIVPVLSESPGRVRNAGPA
TH_3339|M.thermoresistible__bu PKEMLADPQFRARESITSVDHPVLG-EIQMQNVFPRLSRTRGSIRWPGPG
Mb3300|M.bovis_AF2122/97 WKQVVDTPLFAESDLTLEVGRGADTITVIRT---PARYASFRAVVTDPPP
Rv3272|M.tuberculosis_H37Rv WKQVVDTPLFAENDLTLEVGRGADTITVIRT---PARYASFRAVVTDPPP
MUL_2621|M.ulcerans_Agy99 WKQVVTTPLFAENELALQVDSGDDAVTVIRT---PARYSSFSAVLADPPP
MSMEG_3981|M.smegmatis_MC2_155 LEQALAEEQVKVNDRRVTVEVPHQGERAVIG--HPVHLSGAAPRTRHNVP
MMAR_4713|M.marinum_M TLQAADDAQVRANEY-----VVRAGELELVA--NPVQFDVAAPQTGP-AP
Mflv_1791|M.gilvum_PYR-GCK PDALFDDPHLNAVGLFETVDTPHG-PVKFPG--VPTWFSRTPGKVRGPAP
Mvan_1126|M.vanbaalenii_PYR-1 TDELFTDAHLEAVGFFETVQTAHG-PVRFPG--VPTGFSRTPGRVRGGAP
. *
MAB_4651c|M.abscessus_ATCC_199 RPGQDNDDVYVGLLGKSAQDIERLRAEGVL
MAV_4024|M.avium_104 RPGQHNDEVYRGLLGKTAEELEELRAQEVL
TH_3339|M.thermoresistible__bu -LGEHTDEVLR-QLGLSDEELQKLHDAGVV
Mb3300|M.bovis_AF2122/97 TAGEHNAVFLARP-----------------
Rv3272|M.tuberculosis_H37Rv TAGEHNAVFLARP-----------------
MUL_2621|M.ulcerans_Agy99 ATGEHNETLLGES-----------------
MSMEG_3981|M.smegmatis_MC2_155 LPGQHGTEILQELGFDDGQIATLRRARVVG
MMAR_4713|M.marinum_M GFAEQTDDILLELGFDWDRIIELKTAGAVT
Mflv_1791|M.gilvum_PYR-GCK ELGADTAAVLAELGLDTVAAEQVS------
Mvan_1126|M.vanbaalenii_PYR-1 RLGEHTAEVLAEVGIAPPD-----------
. . .