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M. smegmatis MC2 155 MSMEG_3959 (-)

annotation: transcriptional regulator
coordinates: 4029539 - 4030411
length: 290

VPFEPVQRPAGLSDLAYEQLRSRILDGDFPAEGRMSVVSIAEQLKMSRSPVRAAVERLVTEGLLVVTAVG
IELAQLDHVDLIDGLRVRSRLEGLAARLTTDRLTDADLDRLRENLTQFDTAVRGGDTVAARKLDLEFHST
IRDRCGNGLLIENLRRVQARVIVATYMTAWVPAHEVVIDEHRTILKAFEARDADAAEHAAIEHLERLIER
VVHHFGGPDGTVGTSFVRPLAHVPHIRGCDYWNIRWIHVDDPACRIQNRLHAGCRSIDVKGGHHVGRSGR
LATYAQRRCA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3959--100% (290)transcriptional regulator
M. smegmatis MC2 155MSMEG_4057-3e-1831.37% (204) transcriptional regulator, GntR family protein
M. smegmatis MC2 155MSMEG_6639-5e-1733.51% (191) transcriptional regulator, GntR family protein, putative

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0170c-4e-0624.64% (207) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_4366-4e-1530.00% (200) GntR family transcriptional regulator
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4411c-2e-1530.05% (213) GntR family transcriptional regulator
M. marinum MMMAR_4029-2e-0927.54% (207) GntR family transcriptional regulator
M. avium 104MAV_0339-2e-1429.47% (190) transcriptional regulator, GntR family protein
M. thermoresistible (build 8)TH_3038-3e-1528.08% (203) PUTATIVE putative transcriptional regulator, GntR family
M. ulcerans Agy99MUL_3894-7e-0927.05% (207) GntR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1978-2e-1731.50% (200) GntR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4366|M.gilvum_PYR-GCK          ----------------------------------------MTTPEFAARP
Mvan_1978|M.vanbaalenii_PYR-1       ----------------------------------------MSIPEFAARP
MMAR_4029|M.marinum_M               ----------------------------------------MTDPEFAARP
MUL_3894|M.ulcerans_Agy99           ----------------------------------------MTDPEFAARP
Mb0170c|M.bovis_AF2122/97           MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MAV_0339|M.avium_104                ----------------------------------------MAAIDISG--
TH_3038|M.thermoresistible__bu      ----------------------------------------MSRTVESNGD
MSMEG_3959|M.smegmatis_MC2_155      ----------------------------------------MPFEPVQRPA
MAB_4411c|M.abscessus_ATCC_199      -------------------------------------MTTLVPEEFAPLE
                                                                                      

Mflv_4366|M.gilvum_PYR-GCK          ---------QLAEDVARFVRRRIFDGTYPAGRYIRLEQLAAELGISVTPV
Mvan_1978|M.vanbaalenii_PYR-1       ---------QLAEDVARFVRRRIFEGTYPAGQYIRLEQLADELGISVTPV
MMAR_4029|M.marinum_M               ---------QLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
MUL_3894|M.ulcerans_Agy99           ---------QLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
Mb0170c|M.bovis_AF2122/97           RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
MAV_0339|M.avium_104                ---------TVRERAARELRDRILTGALPAGSRIDLDAITAEFATSRTPV
TH_3038|M.thermoresistible__bu      ----------ASERAYQAVLQMILDGEAPAGSWLREQTLAEQIGVSRTPV
MSMEG_3959|M.smegmatis_MC2_155      G---------LSDLAYEQLRSRILDGDFPAEGRMSVVSIAEQLKMSRSPV
MAB_4411c|M.abscessus_ATCC_199      RQ-------STAELIAERLRIAIMRGVLAPGAQLGEASLAAQFAVSRGPL
                                                :     :   *  *   .   :     : ::  *  *:

Mflv_4366|M.gilvum_PYR-GCK          REALFGLRAEGLLTQQPRRGFVVSPITERDIADVSDVQAHIGGVLASRAA
Mvan_1978|M.vanbaalenii_PYR-1       REALFGLRAEGLLTQQPRRGFVVLPITRRDIADVADVQAHIGGVLASRAA
MMAR_4029|M.marinum_M               REALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAARAA
MUL_3894|M.ulcerans_Agy99           REALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAARAA
Mb0170c|M.bovis_AF2122/97           REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
MAV_0339|M.avium_104                REALLELSFEGLVQVAPRSGVTVIGISPEDVLDSFTILGVLTGQAAAWAA
TH_3038|M.thermoresistible__bu      RQALNRLAAEGAIELVPNRGAQVVSFSDEDVEALFDLRARFEPLAVRLAV
MSMEG_3959|M.smegmatis_MC2_155      RAAVERLVTEGLLVVT-AVGIELAQLDHVDLIDGLRVRSRLEGLAARLTT
MAB_4411c|M.abscessus_ATCC_199      REAMQRLVSEGLLRSERNRGIFVIELTDDDVLDVYRSRSAIERAALECIM
                                    * *:  *  ** :      *  :  :   *:       . .         

Mflv_4366|M.gilvum_PYR-GCK          ELITDEQLAELERIQDELEAAYDAV--DHEAAVRLNHAFHRGVNIAAGSP
Mvan_1978|M.vanbaalenii_PYR-1       ERITDEQLQALDHVQDQLEVAYHAD--DHEAAVRLNHEFHRGVNVAAGSP
MMAR_4029|M.marinum_M               INIGAAQLAELQQIQAQLEEAYAAD--DDERTVRLNHEFHRAINLAADSP
MUL_3894|M.ulcerans_Agy99           INIGAAQLAELQQIQAQLEEAYAAD--DDERTVRLNHEFHRAINLAADSP
Mb0170c|M.bovis_AF2122/97           AHITDVEIDELDRINNALAGAIGSG--DAKTIASIEFAFHRVFNKASRRI
MAV_0339|M.avium_104                ERIGPEELATLRELAAEVVAKSG-----DDSIGEANWHFHQMIHRAAHSP
TH_3038|M.thermoresistible__bu      PQLTEERIAELADLATRMEALLDRRPLDTHQMSRLNNAFHGIFLAEAGNR
MSMEG_3959|M.smegmatis_MC2_155      DRLTDADLDRLRENLTQFDTAVRGG--DTVAARKLDLEFHSTIRDRCGNG
MAB_4411c|M.abscessus_ATCC_199      TGDTVTAYRRLLVPVAVMTEAAARG--DVVAVTDADQDFHEVLVDCSGSP
                                              *      .                 :  **  .   .   

Mflv_4366|M.gilvum_PYR-GCK          KLAQLMGQITR--FALESVYPTVEGWPAHSMNDHRVLLAALRKRDGTAAR
Mvan_1978|M.vanbaalenii_PYR-1       KLAQLMGQITK--FALESVYPTVEGWPAHSTRDHRELLAALKARDSEAAR
MMAR_4029|M.marinum_M               RLSQLMSQITR--YQPESVFPGIEHWPARAVKDHRRVLVALKKHDDKAAR
MUL_3894|M.ulcerans_Agy99           RLSQLMSQITR--YQPESVFPGIEHWPARAVKDHGQVLVALKKHDDKAAR
Mb0170c|M.bovis_AF2122/97           KLAWFLLNAAR--YMPAQVFAADPRWGADAVNSHRQLIAALRRRDTAAVI
MAV_0339|M.avium_104                RLANQIKHAAR--VVPTNFLTLFPEHEKHSLDEHAQLLDALGDKDVERAR
TH_3038|M.thermoresistible__bu      HLTAAMQAVVRPALVTLTFQKYSERALRLSMHHHAELVEAARARDPEWAE
MSMEG_3959|M.smegmatis_MC2_155      LLIENLRRVQAR-VIVATYMTAWVPAHEVVIDEHRTILKAFEARDADAAE
MAB_4411c|M.abscessus_ATCC_199      RLRRAMRTLLLETRMLLGELQGAYPDLSEQVREHEVLCAAIGAGDAPAAY
                                     *   :                           *  :  *    *   . 

Mflv_4366|M.gilvum_PYR-GCK          DAMSEHLCAAAGPLIDHLTTRGVIG-------------------------
Mvan_1978|M.vanbaalenii_PYR-1       AAMSEHLCAASGPLIEHLTRRGVIQ-------------------------
MMAR_4029|M.marinum_M               TAMSEHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG----------
MUL_3894|M.ulcerans_Agy99           TAMSEHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG----------
Mb0170c|M.bovis_AF2122/97           EHTVWQFTDGARRLTEALAETEVFG-------------------------
MAV_0339|M.avium_104                AIAERHVLDAGRSLAEWLEQRRDGER------------------------
TH_3038|M.thermoresistible__bu      AVMRAHILAARHAGE-----------------------------------
MSMEG_3959|M.smegmatis_MC2_155      HAAIEHLERLIERVVHHFGGPDGTVGTSFVRPLAHVPHIRGCDYWNIRWI
MAB_4411c|M.abscessus_ATCC_199      RLIDEHMHDAVTRLMARRDPGSVE--------------------------
                                         :.                                           

Mflv_4366|M.gilvum_PYR-GCK          -------------------------------------------
Mvan_1978|M.vanbaalenii_PYR-1       -------------------------------------------
MMAR_4029|M.marinum_M               -------------------------------------------
MUL_3894|M.ulcerans_Agy99           -------------------------------------------
Mb0170c|M.bovis_AF2122/97           -------------------------------------------
MAV_0339|M.avium_104                -------------------------------------------
TH_3038|M.thermoresistible__bu      -------------------------------------------
MSMEG_3959|M.smegmatis_MC2_155      HVDDPACRIQNRLHAGCRSIDVKGGHHVGRSGRLATYAQRRCA
MAB_4411c|M.abscessus_ATCC_199      -------------------------------------------