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QPLLARHAGDINRRRPDEVIDALTQAGLFRMLTPRRFGGYAVAPRTVVEVSETVAMTDASAGWVAGLTPM SRGLLPTAPSRCSLRERTDARVKAALAAVPPE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3911 | - | - | 100% (103) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_6038 | - | 5e-06 | 36.36% (55) | pigment production hydroxylase |
| M. smegmatis MC2 155 | MSMEG_2892 | - | 5e-06 | 37.25% (51) | pigment production hydroxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3121c | - | 1e-08 | 38.57% (70) | hypothetical protein Mb3121c |
| M. gilvum PYR-GCK | Mflv_1463 | - | 2e-06 | 32.86% (70) | acyl-CoA dehydrogenase type 2 |
| M. tuberculosis H37Rv | Rv3094c | - | 1e-08 | 38.57% (70) | hypothetical protein Rv3094c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0075 | - | 3e-09 | 38.24% (68) | putative hydroxylase |
| M. marinum M | MMAR_1556 | - | 5e-08 | 38.03% (71) | dehydrogenase |
| M. avium 104 | MAV_3020 | - | 9e-06 | 33.33% (54) | pigment production hydroxylase |
| M. thermoresistible (build 8) | TH_3644 | - | 2e-07 | 42.19% (64) | PUTATIVE putative pigment production hydroxylase |
| M. ulcerans Agy99 | MUL_3474 | - | 4e-08 | 38.03% (71) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5308 | - | 6e-07 | 34.29% (70) | acyl-CoA dehydrogenase type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3121c|M.bovis_AF2122/97 -----------MNQ----------SETEIEILAEKIARWARARSAEIERD
Rv3094c|M.tuberculosis_H37Rv -----------MNQ----------SETEIEILAEKIARWARARSAEIERD
MMAR_1556|M.marinum_M -----------MNQPDLSAAPLRRADSEMENLAEKIALTAREMSAEIDRD
MUL_3474|M.ulcerans_Agy99 MTEPPSLPGVLMNQPDLSAAPLRRADSEMEDLAEKIALTAREMSAEIDRD
Mflv_1463|M.gilvum_PYR-GCK -----------------MTSIEQRDAQTVLAGVNDLLPRIAKRSAAAEEL
Mvan_5308|M.vanbaalenii_PYR-1 -----------------MTSIQQRDAQSVLAGIDDLLPRIAKRSQAAEEL
MAB_0075|M.abscessus_ATCC_1997 ------------MEGQRGGRTIVAMTERVIDRINDLAEQLREQAWEAEKL
MAV_3020|M.avium_104 ------------------------MSERVIDRVMAMADQLRDQAAEAEQL
TH_3644|M.thermoresistible__bu ---------MTQTINTNNHPDLEATRREVLAAVDDILPVLERNADTAEKN
MSMEG_3911|M.smegmatis_MC2_155 -----------------------------------MQPLLARHAGDIN--
: : :
Mb3121c|M.bovis_AF2122/97 RRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAG
Rv3094c|M.tuberculosis_H37Rv RRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAG
MMAR_1556|M.marinum_M RRLPDELVARLGEAGLLRATMPREVQAAELAPGPALRCAEAVARGDASAG
MUL_3474|M.ulcerans_Agy99 RRLPDELVARLGEAGLLRATMPREVQAAELAPGPALRCAEAVARGDASAG
Mflv_1463|M.gilvum_PYR-GCK RRLPDETVAELDEVGFFKLLQPEQWGGLQCDPTLFYEAVRRIASACGSTG
Mvan_5308|M.vanbaalenii_PYR-1 RRLPDETVTELDEVGFFKLLQPEQWGGLQCDPTIFYEAVRRIASACGSTG
MAB_0075|M.abscessus_ATCC_1997 GRLPDETAKMLKAAGLIRLLQPQKYGGYEAHPREFAETVMTTAALDPASG
MAV_3020|M.avium_104 GRLTDDTVKLMKGAGLIRLLQTKQYQGFEVHPREFAETVMATAALDPAAG
TH_3644|M.thermoresistible__bu RAVPQESWDALIESSALRLFAPRRAGGLEAGYRTYVEVTAKVAGACGSSG
MSMEG_3911|M.smegmatis_MC2_155 RRRPDEVIDALTQAGLFRMLTPRRFGGYAVAPRTVVEVSETVAMTDASAG
.:: : . :: ... . . * ::*
Mb3121c|M.bovis_AF2122/97 WCVSIAITSALLVAYLPARSREEMFGG--GRGVAAG-VWAPRGTARSVDG
Rv3094c|M.tuberculosis_H37Rv WCVSIAITSALLVAYLPARSREEMFGG--GRGVAAG-VWAPRGTARSVDG
MMAR_1556|M.marinum_M WCVSIAITSALLVAYLPASSRDEMFGA--GRSVAAG-VWAPRGKAKSVDG
MUL_3474|M.ulcerans_Agy99 WCVSIAITSALLVAYLPASSRDEMFGA--GRSVAAG-VWAPRGKAKSVDG
Mflv_1463|M.gilvum_PYR-GCK WVSSIIGVHNWHLALFDQKAQEDVWGD--DPTVRVSSSYAPMGAGTVVDG
Mvan_5308|M.vanbaalenii_PYR-1 WVASIIGVHNWHLALFDQQAQEEVWGS--DPTVRVSSSYAPMGAGTVVDG
MAB_0075|M.abscessus_ATCC_1997 WICGVVGVHPWQVAFADSRVAEEMWGE--DQDIWMASPYAPTGVAKPVDG
MAV_3020|M.avium_104 WIVGVVGVHPYQLAYADPKVAAEVWAD--DVDTWMASPYAPQGVAKPVNG
TH_3644|M.thermoresistible__bu WFCFILNHGDWHIGQMSQAVQDKVWANGATEKVIVPLTPAPGSSIERVDG
MSMEG_3911|M.smegmatis_MC2_155 WVAGLTPMSRGLLPTAPSRCSLRERTD---ARVKAALAAVPPE-------
* : : .*
Mb3121c|M.bovis_AF2122/97 GVVVSGRWPFCSGINHADIMFAG--CFVDDR-------QVPSVVALNKDE
Rv3094c|M.tuberculosis_H37Rv GVVVSGRWPFCSGINHADIMFAG--CFVDDR-------QVPSVVALNKDE
MMAR_1556|M.marinum_M GVVVSGRWPFCSGINHADMMFAG--CFVEGQ-------PVPSVVALPKDD
MUL_3474|M.ulcerans_Agy99 GVVVSGRWPFCSGINHADMMFAG--CFVEGQ-------PVPSVVALPKDD
Mflv_1463|M.gilvum_PYR-GCK GYLVSGAWQWSSGCDHATWAFLGGPVIKDGK-----PVDFGSFLIPRTDY
Mvan_5308|M.vanbaalenii_PYR-1 GYLVSGAWQWSSGCDHATWAFLGGPVIKDGK-----PVDFGSFLIPRTEY
MAB_0075|M.abscessus_ATCC_1997 GYIFNGRWQFSSGTDHCDWIILG-AMLGDADGTPIMPPKMLHMILPRADY
MAV_3020|M.avium_104 GYIFNGRWQFSSGTDHCDWIILG-AMLGDEQGVPLMPPQMLHMILPRKDY
TH_3644|M.thermoresistible__bu GTKLTGEWPYSSGSDRAKWGVMGFPVFGPDG----TPVDNAIGLISMDQA
MSMEG_3911|M.smegmatis_MC2_155 --------------------------------------------------
Mb3121c|M.bovis_AF2122/97 LQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFS---VFDGPI-----VD
Rv3094c|M.tuberculosis_H37Rv LQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFS---VFDGPI-----VD
MMAR_1556|M.marinum_M LRALDTWHTLGLRGTGSHDCVAEEVFVPADRVFS---VFDGPS-----ID
MUL_3474|M.ulcerans_Agy99 LRALDTWHTLGLCGTGSHDCVAEEVFVPADRVFS---VFDGPT-----ID
Mflv_1463|M.gilvum_PYR-GCK R-IDDVWNVVGLKATGSNTVVVKDVFVPRHRFLSYKAMNDGTAGGYENNT
Mvan_5308|M.vanbaalenii_PYR-1 R-IDDVWNVVGLKATGSNNVVVKDVFVPRHRFLSYKAMNDGTAGGYQNNT
MAB_0075|M.abscessus_ATCC_1997 QIVEDSWNVVGLRGTGSKDIIVNDAFVPSYRVMDGDQVIDGTAQRDAGMT
MAV_3020|M.avium_104 EIVEDSWNVVGLRGTGSKDVIVKDAFVPSYRTMDATKVMDGTAQREAGMT
TH_3644|M.thermoresistible__bu EGIKDTWHVSGMAGTSSNTVVLKDVVIPDEETITFGEIMSGNFR-TPHKH
MSMEG_3911|M.smegmatis_MC2_155 --------------------------------------------------
Mb3121c|M.bovis_AF2122/97 RPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGGKKGLGSTR---TL
Rv3094c|M.tuberculosis_H37Rv RPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGGKKGLGSTR---TL
MMAR_1556|M.marinum_M RPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGDKKGLGAKR---TL
MUL_3474|M.ulcerans_Agy99 RPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGDKKGLGAKR---TL
Mflv_1463|M.gilvum_PYR-GCK APVYKMPWGTMHPTTISAPIMGMAYGAYEAHVEHQGKRVRAAFAGE--KS
Mvan_5308|M.vanbaalenii_PYR-1 APVYKMPWGTMHPTTISAPIMGMAYGAYDAHVEHQGKRVRAAFAGE--KS
MAB_0075|M.abscessus_ATCC_1997 DTLYRMPWSTMFPLGISSAVIGIAEGALAAHLEYQ--RERVGAQGT--AV
MAV_3020|M.avium_104 EPLYLMPWSTMFPLGISAATIGIAEGALAAHLDYQ--RSRVGATGT--AI
TH_3644|M.thermoresistible__bu EAQYHQDAGTIFHVATLAPVLGLARAAYEYVLRRITSSPKAMAYTFYTDT
MSMEG_3911|M.smegmatis_MC2_155 --------------------------------------------------
Mb3121c|M.bovis_AF2122/97 AERSATQAAAATAESALGAARALFYEVIEAAWQVSHDAE----------A
Rv3094c|M.tuberculosis_H37Rv AERSATQAAAATAESALGAARALFYEVIEAAWQVSHDAE----------A
MMAR_1556|M.marinum_M AERSATQTAVATAEAALGAARALFYEAIDSAWQASHNPD----------P
MUL_3474|M.ulcerans_Agy99 AERSATQTAVATAEAALGAARALFYEAIDSAWQASHNPDPVPVPVPVPVP
Mflv_1463|M.gilvum_PYR-GCK KDDPFAKIRIAEAASDIDAGWRQLIGNVRDEYELLQAGK----------E
Mvan_5308|M.vanbaalenii_PYR-1 KDDPFAKIRIAEAASDIDAGWRQLIGNVGAEYRLLEAGE----------E
MAB_0075|M.abscessus_ATCC_1997 KDDPYVLFAIGEAAADINAARQEILANVDKIWGIVDSGK----------E
MAV_3020|M.avium_104 KDDPYVMYAIGEAAADINAARQELLANADRIYDIVASGK----------E
TH_3644|M.thermoresistible__bu TKSSATQFAMARASWLIDTAFDQMLATADAIDAQARTGK----------P
MSMEG_3911|M.smegmatis_MC2_155 --------------------------------------------------
Mb3121c|M.bovis_AF2122/97 VPVTMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAPLQRRFRDAF
Rv3094c|M.tuberculosis_H37Rv VPVTMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAPLQRRFRDAF
MMAR_1556|M.marinum_M VPVALRNRLRLAATHAARTSADVVRIMYDLAGSSAIYDGSPLQRRFRDAF
MUL_3474|M.ulcerans_Agy99 VPVALRNRLRLAATHAARTSADVVRTMYDLAGSSAIYDGSPLQRRFRDAF
Mflv_1463|M.gilvum_PYR-GCK IPFSLRASARRDQVRATARAIASIDLLFEASGATALQLDQPVQRFWRDAH
Mvan_5308|M.vanbaalenii_PYR-1 IPFSLRAAARRDQVRATARAIASIDLLFEASGATALQLDQPVQRFWRDAH
MAB_0075|M.abscessus_ATCC_1997 VSFADRAAGRRTQVRAAWRAVMAVDQIFSRSGGNAMRLDKPLQRYWRDAH
MAV_3020|M.avium_104 VSFVDRAAGRRTQVRAVWRAVSAVDEIFARSGGNAARMDKPLQRYWRDVH
TH_3644|M.thermoresistible__bu FSNAERARFAMKAAEGHRMCREAFDLVLDVNGAGSFALASPLQRMWRDMH
MSMEG_3911|M.smegmatis_MC2_155 --------------------------------------------------
Mb3121c|M.bovis_AF2122/97 TATAHFQVN-EASRELPGRVLLDQPA----DVSML
Rv3094c|M.tuberculosis_H37Rv TATAHFQVN-EASRELPGRVLLDQPA----DVSML
MMAR_1556|M.marinum_M TATAHFQVN-EASRELPGRVLLGQHC----DTSML
MUL_3474|M.ulcerans_Agy99 TATAHFQVN-EASRELPGRVLLGQHC----DTSML
Mflv_1463|M.gilvum_PYR-GCK AGRVHAANEPERAYLIFGNDAFGLPP----QDTMV
Mvan_5308|M.vanbaalenii_PYR-1 AGRVHAANEPERAYLIFGNDAFGLPP----QDTMV
MAB_0075|M.abscessus_ATCC_1997 TGLAHAIHVPSTVFHASALSSLGIEP-QGPLRSMI
MAV_3020|M.avium_104 VGQMHAIHVPGTTYHASALSSIGIDPPEGPLRALI
TH_3644|M.thermoresistible__bu MGSRHGLSVPGLKHEVYGRSLLGAPE--QQMTPIL
MSMEG_3911|M.smegmatis_MC2_155 -----------------------------------