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M. thermoresistible (build 8) TH_3644 (-)

annotation: putative pigment production hydroxylase
coordinates: 145753 - 146982
length: 410

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3644--100% (410)putative pigment production hydroxylase
M. thermoresistible (build 8)TH_1742-1e-4932.05% (390) POSSIBLE OXIDOREDUCTASE
M. thermoresistible (build 8)TH_3059-4e-3526.40% (394) PUTATIVE pigment production hydroxylase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3601c-2e-4831.03% (390) oxidoreductase
M. gilvum PYR-GCKMflv_1463-3e-4831.19% (388) acyl-CoA dehydrogenase type 2
M. tuberculosis H37RvRv3570c-9e-4830.77% (390) oxidoreductase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0584-2e-4428.87% (388) hypothetical protein MAB_0584
M. marinum MMMAR_5065-1e-4932.56% (390) acyl-CoA dehydrogenase
M. avium 104MAV_0591-5e-4731.44% (388) pigment production hydroxylase
M. smegmatis MC2 155MSMEG_6038-2e-5232.90% (386) pigment production hydroxylase
M. ulcerans Agy99MUL_4141-2e-4932.31% (390) acyl-CoA dehydrogenase
M. vanbaalenii PYR-1Mvan_5308-5e-4930.51% (390) acyl-CoA dehydrogenase type 2

CLUSTAL 2.0.9 multiple sequence alignment


Mb3601c|M.bovis_AF2122/97           ----MTSIQQR----DAQSVLAAIDDLLPEIRDRAQATEDLRRLPDETVK
Rv3570c|M.tuberculosis_H37Rv        ----MTSIQQR----DAQSVLAAIDNLLPEIRDRAQATEDLRRLPDETVK
MMAR_5065|M.marinum_M               ----MTTIQQR----DAQSVLAAIDDLLPQLRERAQATEDLRRLPDETVQ
MUL_4141|M.ulcerans_Agy99           ----MTTIQQR----DAQSVLAAIDDLLPQLRERAQATEDLRRLPDETVQ
MAV_0591|M.avium_104                ----MTSIQQR----DAQSVLAGIDDLLPRIRERAQATEDLRRLPDETVA
MAB_0584|M.abscessus_ATCC_1997      ----MTTTEQREHSDEVLSVLSQIDDLLPTLRKRAQETEDLRRLPDATVA
Mflv_1463|M.gilvum_PYR-GCK          ----MTSIEQR----DAQTVLAGVNDLLPRIAKRSAAAEELRRLPDETVA
Mvan_5308|M.vanbaalenii_PYR-1       ----MTSIQQR----DAQSVLAGIDDLLPRIAKRSQAAEELRRLPDETVT
MSMEG_6038|M.smegmatis_MC2_155      ----MTSIEQR----DVQAVLAGVDDLLPKLRERAQAAEELRQIPQESID
TH_3644|M.thermoresistible__bu      MTQTINTNNHPDLEATRREVLAAVDDILPVLERNADTAEKNRAVPQESWD
                                        :.: ::         **: ::::** :  .:  :*. * :*: :  

Mb3601c|M.bovis_AF2122/97           ALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGSTGWVSSIVGVH
Rv3570c|M.tuberculosis_H37Rv        ALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGSTGWVSSIVGVH
MMAR_5065|M.marinum_M               ALEDVGFFTLLQPEQWGGLQCDPTLFYEATRRLASACGSTGWVSSIIGVH
MUL_4141|M.ulcerans_Agy99           ALEDVGFFTLLQPEQWGGLQCDPTLFYEATRRLASACGSTGWVSSIIGVH
MAV_0591|M.avium_104                DLQDVGFFTLLQPEQWGGLQCDPTLFYEAVRRLASACGSTGWVSSIIGVH
MAB_0584|M.abscessus_ATCC_1997      ELQEIGFFKLLQPSQWGGYETAPTTFYEAVRRLGSACGSTGWVASIIGVH
Mflv_1463|M.gilvum_PYR-GCK          ELDEVGFFKLLQPEQWGGLQCDPTLFYEAVRRIASACGSTGWVSSIIGVH
Mvan_5308|M.vanbaalenii_PYR-1       ELDEVGFFKLLQPEQWGGLQCDPTIFYEAVRRIASACGSTGWVASIIGVH
MSMEG_6038|M.smegmatis_MC2_155      ELDEIGFFKLLQPEQWGGLQADPTVFYEAVRRLASACGSTGWVASIIGVH
TH_3644|M.thermoresistible__bu      ALIESSALRLFAPRRAGGLEAGYRTYVEVTAKVAGACGSSGWFCFILNHG
                                     * : . : *: * : ** :     : *.. ::...***:**.. *:.  

Mb3601c|M.bovis_AF2122/97           NWHLALFDQRAQEEVWGEDPSTRISSSYAPMGAGVVVDG--GYLVNGSWN
Rv3570c|M.tuberculosis_H37Rv        NWHLALFDQRAQEEVWGEDPSTRISSSYAPMGAGVVVDG--GYLVNGSWN
MMAR_5065|M.marinum_M               NWHLALFDQLAQEEVWGSDPKTRISSSYAPMGAGVVVDG--GYLVNGSWN
MUL_4141|M.ulcerans_Agy99           NWHLALFDQLAQEEVWGSDPKTRISSSYAPMGAGVVVDG--GYLVNGSWN
MAV_0591|M.avium_104                NWHLALFDQQAQEEVWGEDPNVRISSSYAPMGAGVVTDG--GYLVNGSWN
MAB_0584|M.abscessus_ATCC_1997      NWHLALFDQQAQEEVWGDDTDVRVSSSYAPMGAGVVTDAGDGYLVNGSWN
Mflv_1463|M.gilvum_PYR-GCK          NWHLALFDQKAQEDVWGDDPTVRVSSSYAPMGAGTVVDG--GYLVSGAWQ
Mvan_5308|M.vanbaalenii_PYR-1       NWHLALFDQQAQEEVWGSDPTVRVSSSYAPMGAGTVVDG--GYLVSGAWQ
MSMEG_6038|M.smegmatis_MC2_155      NWHLALFDQKAQDEVWGDDPTVRVSSSYAPMGAGVVTETGDGYIVNGAWQ
TH_3644|M.thermoresistible__bu      DWHIGQMSQAVQDKVWANGATEKVIVPLTPAPGSSIERVDGGTKLTGEWP
                                    :**:. :.* .*:.**....  ::  . :*  .. :     *  :.* * 

Mb3601c|M.bovis_AF2122/97           WSSGCDHASWTFVGGPVIK-DGRPVDFGSFLIPRSEYE-IKDVWYVVGLR
Rv3570c|M.tuberculosis_H37Rv        WSSGCDHASWTFVGGPVIK-DGRPVDFGSFLIPRSEYE-IKDVWYVVGLR
MMAR_5065|M.marinum_M               WSSGCDHATWCFAGGPVIK-DGRPVDFGSFLIPRTEYR-IDDVWHVVGLR
MUL_4141|M.ulcerans_Agy99           WSSGCDHGTWCFAGGPVIK-DGRPVDFGSFLIPRTEYR-IDDVWHVVGLR
MAV_0591|M.avium_104                WSSGCDHATWAFLGGPVIK-DGRPVDFGSFLIPRSEYR-IDDVWHVVGLR
MAB_0584|M.abscessus_ATCC_1997      WSSGCDHATWAFLGGPVIK-DGRPVDFGSFLIPRTEYR-IDDVWNVVGLR
Mflv_1463|M.gilvum_PYR-GCK          WSSGCDHATWAFLGGPVIK-DGKPVDFGSFLIPRTDYR-IDDVWNVVGLK
Mvan_5308|M.vanbaalenii_PYR-1       WSSGCDHATWAFLGGPVIK-DGKPVDFGSFLIPRTEYR-IDDVWNVVGLK
MSMEG_6038|M.smegmatis_MC2_155      WSSGSEHATWAFLGGPVIK-DGRPVDFGSFLIPRTEYT-IDDVWHVVGLR
TH_3644|M.thermoresistible__bu      YSSGSDRAKWGVMGFPVFGPDGTPVDNAIGLISMDQAEGIKDTWHVSGMA
                                    :***.::..* . * **:  ** *** .  **.  :   *.*.* * *: 

Mb3601c|M.bovis_AF2122/97           GTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHP
Rv3570c|M.tuberculosis_H37Rv        GTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHP
MMAR_5065|M.marinum_M               GTGSNTVVVKDVFVPRHRFLSYKAMNDHTAGGLQTNTAPVYKMPWGTMHP
MUL_4141|M.ulcerans_Agy99           GTGSNTVVVKDVFVPRHRFLSYKAMNDHTAGGLQTNTAPVYKMPWGTMHP
MAV_0591|M.avium_104                GTGSNTVVVKDVFVPRHRFLSYKAMNDGTAGGYETNTAPVYKMPWGTMHP
MAB_0584|M.abscessus_ATCC_1997      GTGSNTVVVKDVFVPKHRFLSYKKMNDQTAGGYQTNTAPVYKMPWGTMHP
Mflv_1463|M.gilvum_PYR-GCK          ATGSNTVVVKDVFVPRHRFLSYKAMNDGTAGGYENNTAPVYKMPWGTMHP
Mvan_5308|M.vanbaalenii_PYR-1       ATGSNNVVVKDVFVPRHRFLSYKAMNDGTAGGYQNNTAPVYKMPWGTMHP
MSMEG_6038|M.smegmatis_MC2_155      GTGSNTIVVKDVFVPRHRFLSYKAMNDGTAGGYATNTAPVYKMPWGTVHP
TH_3644|M.thermoresistible__bu      GTSSNTVVLKDVVIPDEETITFGEIMSGNFR-TPHKHEAQYHQDAGTIFH
                                    .*.**.:*:***.:* .. :::  : . .      :  . *:   **:. 

Mb3601c|M.bovis_AF2122/97           TTISAPIVGMAYGAYAAHVEHQGK--RVRAAFAGEKAKDDPFAKVRIAEA
Rv3570c|M.tuberculosis_H37Rv        TTISAPIVGMAYGAYAAHVEHQGK--RVRAAFAGEKAKDDPFAKVRIAEA
MMAR_5065|M.marinum_M               TTITAPIVGMAYGAYDAHVEHQGK--RVRAAFAGEKAKDDPFAKVRIAEA
MUL_4141|M.ulcerans_Agy99           TTITAPIVGMAYGAYDAHVEHQGK--RVRAAFAGEKAKDDPFAKVRIAEA
MAV_0591|M.avium_104                TTISAPIVGMAYGAYAAHVEHQGK--RVRAAFAGEKAKDDPFAKVRIAEA
MAB_0584|M.abscessus_ATCC_1997      TTITAPIMGMAYGAYDAHVEAQGK--RVRAAYAGEKAKDDPFTKVRVAEA
Mflv_1463|M.gilvum_PYR-GCK          TTISAPIMGMAYGAYEAHVEHQGK--RVRAAFAGEKSKDDPFAKIRIAEA
Mvan_5308|M.vanbaalenii_PYR-1       TTISAPIMGMAYGAYDAHVEHQGK--RVRAAFAGEKSKDDPFAKIRIAEA
MSMEG_6038|M.smegmatis_MC2_155      TTISAPIVGMAYGAYAAHVEHQGK--RVRAAFAGEKSKDDPFAKVRIAEA
TH_3644|M.thermoresistible__bu      VATLAPVLGLARAAYEYVLRRITSSPKAMAYTFYTDTTKSSATQFAMARA
                                    .:  **::*:* .**   :.   .  :. *     .:.... ::. :*.*

Mb3601c|M.bovis_AF2122/97           ASDIDAAWRQLIGNVSDEYALLAAGKEIPFELRARARRDQVRATGRSIAS
Rv3570c|M.tuberculosis_H37Rv        ASDIDAAWRQLIGNVSDEYALLAAGKEIPFELRARARRDQVRATGRSIAS
MMAR_5065|M.marinum_M               ASDIDAAWRQLMGNVGDEYALLSAGKEIPFDLRTRARRDQVRATGRSIAS
MUL_4141|M.ulcerans_Agy99           ASDIDAAWRQLMGNVGDEYALLSAGKEIPFDLRTRARRDQVRATGRSIAS
MAV_0591|M.avium_104                ASDIDAAWRQLSGNVADEYALLSAGKEIPFELRARARRDQVRATGRAIAS
MAB_0584|M.abscessus_ATCC_1997      ASDIDAGWRQLIGNVGDEYALIAAGQEVPFELRAAARRDQVRATGRAIAS
Mflv_1463|M.gilvum_PYR-GCK          ASDIDAGWRQLIGNVRDEYELLQAGKEIPFSLRASARRDQVRATARAIAS
Mvan_5308|M.vanbaalenii_PYR-1       ASDIDAGWRQLIGNVGAEYRLLEAGEEIPFSLRAAARRDQVRATARAIAS
MSMEG_6038|M.smegmatis_MC2_155      ASDIDAAWRQLIGNVGEEYELLKAGKEIPFDLRARARRDQVRATGRAIAS
TH_3644|M.thermoresistible__bu      SWLIDTAFDQMLATADAIDAQARTGKPFSNAERARFAMKAAEGHRMCREA
                                    :  **:.: *: ...        :*: ..   *:    . ...   .  :

Mb3601c|M.bovis_AF2122/97           IDRLFEASGATALSNEAPIQRFWRDAHAGRVHAANDPERAYVIFGNHEFG
Rv3570c|M.tuberculosis_H37Rv        IDRLFEASGATALSNEAPIQRFWRDAHAGRVHAANDPERAYVIFGNHEFG
MMAR_5065|M.marinum_M               IDRLFEASGATALANDAPIQRFWRDAHAGRVHAANDPERAYVIFGNNEFG
MUL_4141|M.ulcerans_Agy99           IDRLFEASGATALANDAPIQRFWRDAHAGRVHAANDPERAYVIFGNNEFG
MAV_0591|M.avium_104                IDRLFEASGATALANDQPVQRFWRDAHAGRVHAANDPERAYQIFGNHEFG
MAB_0584|M.abscessus_ATCC_1997      IDLLFENSGATALSNDAPVQRFWRDAHAGRVHAANDAERAYQIWGNHAFE
Mflv_1463|M.gilvum_PYR-GCK          IDLLFEASGATALQLDQPVQRFWRDAHAGRVHAANEPERAYLIFGNDAFG
Mvan_5308|M.vanbaalenii_PYR-1       IDLLFEASGATALQLDQPVQRFWRDAHAGRVHAANEPERAYLIFGNDAFG
MSMEG_6038|M.smegmatis_MC2_155      IDLLFESAGATALINTAPLQRFWRDAHAGRVHAANEPERAYLIFGNHEFG
TH_3644|M.thermoresistible__bu      FDLVLDVNGAGSFALASPLQRMWRDMHMGSRHGLSVPGLKHEVYGRSLLG
                                    :* :::  ** ::    *:**:*** * *  *. . .   : ::*.  : 

Mb3601c|M.bovis_AF2122/97           LPPGDTMV--
Rv3570c|M.tuberculosis_H37Rv        LPPGDTMV--
MMAR_5065|M.marinum_M               LPAGDTMV--
MUL_4141|M.ulcerans_Agy99           LPAGDTMV--
MAV_0591|M.avium_104                LPPGDTMV--
MAB_0584|M.abscessus_ATCC_1997      LPATDTMV--
Mflv_1463|M.gilvum_PYR-GCK          LPPQDTMV--
Mvan_5308|M.vanbaalenii_PYR-1       LPPQDTMV--
MSMEG_6038|M.smegmatis_MC2_155      LPPADTMV--
TH_3644|M.thermoresistible__bu      APEQQMTPIL
                                     *  :