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TSIQQRDAQSVLAGIDDLLPRIAKRSQAAEELRRLPDETVTELDEVGFFKLLQPEQWGGLQCDPTIFYEA VRRIASACGSTGWVASIIGVHNWHLALFDQQAQEEVWGSDPTVRVSSSYAPMGAGTVVDGGYLVSGAWQW SSGCDHATWAFLGGPVIKDGKPVDFGSFLIPRTEYRIDDVWNVVGLKATGSNNVVVKDVFVPRHRFLSYK AMNDGTAGGYQNNTAPVYKMPWGTMHPTTISAPIMGMAYGAYDAHVEHQGKRVRAAFAGEKSKDDPFAKI RIAEAASDIDAGWRQLIGNVGAEYRLLEAGEEIPFSLRAAARRDQVRATARAIASIDLLFEASGATALQL DQPVQRFWRDAHAGRVHAANEPERAYLIFGNDAFGLPPQDTMV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5308 | - | - | 100% (394) | acyl-CoA dehydrogenase type 2 |
| M. vanbaalenii PYR-1 | Mvan_2892 | - | 1e-80 | 38.60% (386) | acyl-CoA dehydrogenase type 2 |
| M. vanbaalenii PYR-1 | Mvan_1900 | - | 5e-52 | 34.29% (347) | acyl-CoA dehydrogenase type 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3601c | - | 0.0 | 81.98% (394) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1463 | - | 0.0 | 94.67% (394) | acyl-CoA dehydrogenase type 2 |
| M. tuberculosis H37Rv | Rv3570c | - | 0.0 | 81.73% (394) | oxidoreductase |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 3e-08 | 20.97% (372) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0584 | - | 0.0 | 80.75% (400) | hypothetical protein MAB_0584 |
| M. marinum M | MMAR_5065 | - | 0.0 | 84.26% (394) | acyl-CoA dehydrogenase |
| M. avium 104 | MAV_0591 | - | 0.0 | 87.06% (394) | pigment production hydroxylase |
| M. smegmatis MC2 155 | MSMEG_6038 | - | 0.0 | 84.09% (396) | pigment production hydroxylase |
| M. thermoresistible (build 8) | TH_1742 | - | 0.0 | 85.97% (385) | POSSIBLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_4141 | - | 0.0 | 84.01% (394) | acyl-CoA dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3601c|M.bovis_AF2122/97 ------MTSIQQR----DAQSVLAAIDDLLP-EIRDRAQATEDLRRLPDE
Rv3570c|M.tuberculosis_H37Rv ------MTSIQQR----DAQSVLAAIDNLLP-EIRDRAQATEDLRRLPDE
MMAR_5065|M.marinum_M ------MTTIQQR----DAQSVLAAIDDLLP-QLRERAQATEDLRRLPDE
MUL_4141|M.ulcerans_Agy99 ------MTTIQQR----DAQSVLAAIDDLLP-QLRERAQATEDLRRLPDE
MAV_0591|M.avium_104 ------MTSIQQR----DAQSVLAGIDDLLP-RIRERAQATEDLRRLPDE
Mvan_5308|M.vanbaalenii_PYR-1 ------MTSIQQR----DAQSVLAGIDDLLP-RIAKRSQAAEELRRLPDE
Mflv_1463|M.gilvum_PYR-GCK ------MTSIEQR----DAQTVLAGVNDLLP-RIAKRSAAAEELRRLPDE
MSMEG_6038|M.smegmatis_MC2_155 ------MTSIEQR----DVQAVLAGVDDLLP-KLRERAQAAEELRQIPQE
TH_1742|M.thermoresistible__bu ------------------VQAVLAGIDDLLP-RLRERAAKTEELRRLPDE
MAB_0584|M.abscessus_ATCC_1997 ------MTTTEQREHSDEVLSVLSQIDDLLP-TLRKRAQETEDLRRLPDA
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
: : : * : :: .:: ::*:
Mb3601c|M.bovis_AF2122/97 TVKALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGSTGWVSSIV
Rv3570c|M.tuberculosis_H37Rv TVKALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGSTGWVSSIV
MMAR_5065|M.marinum_M TVQALEDVGFFTLLQPEQWGGLQCDPTLFYEATRRLASACGSTGWVSSII
MUL_4141|M.ulcerans_Agy99 TVQALEDVGFFTLLQPEQWGGLQCDPTLFYEATRRLASACGSTGWVSSII
MAV_0591|M.avium_104 TVADLQDVGFFTLLQPEQWGGLQCDPTLFYEAVRRLASACGSTGWVSSII
Mvan_5308|M.vanbaalenii_PYR-1 TVTELDEVGFFKLLQPEQWGGLQCDPTIFYEAVRRIASACGSTGWVASII
Mflv_1463|M.gilvum_PYR-GCK TVAELDEVGFFKLLQPEQWGGLQCDPTLFYEAVRRIASACGSTGWVSSII
MSMEG_6038|M.smegmatis_MC2_155 SIDELDEIGFFKLLQPEQWGGLQADPTVFYEAVRRLASACGSTGWVASII
TH_1742|M.thermoresistible__bu TVEELEEIGFFKLLQPEQWGGMQCDPTLFYEAVRRLASACGSTGWVASII
MAB_0584|M.abscessus_ATCC_1997 TVAELQEIGFFKLLQPSQWGGYETAPTTFYEAVRRLGSACGSTGWVASII
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
:: *: ** : *.::** .. . ..:. . .*:. :.::
Mb3601c|M.bovis_AF2122/97 GVHNWHLALFD-QRAQEEVWGEDPSTRISSSYAP-----------MGAGV
Rv3570c|M.tuberculosis_H37Rv GVHNWHLALFD-QRAQEEVWGEDPSTRISSSYAP-----------MGAGV
MMAR_5065|M.marinum_M GVHNWHLALFD-QLAQEEVWGSDPKTRISSSYAP-----------MGAGV
MUL_4141|M.ulcerans_Agy99 GVHNWHLALFD-QLAQEEVWGSDPKTRISSSYAP-----------MGAGV
MAV_0591|M.avium_104 GVHNWHLALFD-QQAQEEVWGEDPNVRISSSYAP-----------MGAGV
Mvan_5308|M.vanbaalenii_PYR-1 GVHNWHLALFD-QQAQEEVWGSDPTVRVSSSYAP-----------MGAGT
Mflv_1463|M.gilvum_PYR-GCK GVHNWHLALFD-QKAQEDVWGDDPTVRVSSSYAP-----------MGAGT
MSMEG_6038|M.smegmatis_MC2_155 GVHNWHLALFD-QKAQDEVWGDDPTVRVSSSYAP-----------MGAGV
TH_1742|M.thermoresistible__bu GVHNWHLALFD-QQAQEDVWGDDPSVRVSSSYAP-----------MGSGQ
MAB_0584|M.abscessus_ATCC_1997 GVHNWHLALFD-QQAQEEVWGDDTDVRVSSSYAP-----------MGAGV
MLBr_00737|M.leprae_Br4923 KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
: . * * . : :.:* . . :*** * :
Mb3601c|M.bovis_AF2122/97 VVDG--GYLVNGSWNWSSGCDHASWTFVGGPVIKDGRPVDFGSFLIPRSE
Rv3570c|M.tuberculosis_H37Rv VVDG--GYLVNGSWNWSSGCDHASWTFVGGPVIKDGRPVDFGSFLIPRSE
MMAR_5065|M.marinum_M VVDG--GYLVNGSWNWSSGCDHATWCFAGGPVIKDGRPVDFGSFLIPRTE
MUL_4141|M.ulcerans_Agy99 VVDG--GYLVNGSWNWSSGCDHGTWCFAGGPVIKDGRPVDFGSFLIPRTE
MAV_0591|M.avium_104 VTDG--GYLVNGSWNWSSGCDHATWAFLGGPVIKDGRPVDFGSFLIPRSE
Mvan_5308|M.vanbaalenii_PYR-1 VVDG--GYLVSGAWQWSSGCDHATWAFLGGPVIKDGKPVDFGSFLIPRTE
Mflv_1463|M.gilvum_PYR-GCK VVDG--GYLVSGAWQWSSGCDHATWAFLGGPVIKDGKPVDFGSFLIPRTD
MSMEG_6038|M.smegmatis_MC2_155 VTETGDGYIVNGAWQWSSGSEHATWAFLGGPVIKDGRPVDFGSFLIPRTE
TH_1742|M.thermoresistible__bu VVDG--GYLVSGAWQWSSGCDHATWTFVGGPVIKDGRPVDFGSFLIPNTD
MAB_0584|M.abscessus_ATCC_1997 VTDAGDGYLVNGSWNWSSGCDHATWAFLGGPVIKDGRPVDFGSFLIPRTE
MLBr_00737|M.leprae_Br4923 KADG-DDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKDD
.: .:::.* * :. :.:* . . * . .:.:*:: . :
Mb3601c|M.bovis_AF2122/97 --YEIKDVWYVVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLAT
Rv3570c|M.tuberculosis_H37Rv --YEIKDVWYVVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLAT
MMAR_5065|M.marinum_M --YRIDDVWHVVGLRGTGSNTVVVKDVFVPRHRFLSYKAMNDHTAGGLQT
MUL_4141|M.ulcerans_Agy99 --YRIDDVWHVVGLRGTGSNTVVVKDVFVPRHRFLSYKAMNDHTAGGLQT
MAV_0591|M.avium_104 --YRIDDVWHVVGLRGTGSNTVVVKDVFVPRHRFLSYKAMNDGTAGGYET
Mvan_5308|M.vanbaalenii_PYR-1 --YRIDDVWNVVGLKATGSNNVVVKDVFVPRHRFLSYKAMNDGTAGGYQN
Mflv_1463|M.gilvum_PYR-GCK --YRIDDVWNVVGLKATGSNTVVVKDVFVPRHRFLSYKAMNDGTAGGYEN
MSMEG_6038|M.smegmatis_MC2_155 --YTIDDVWHVVGLRGTGSNTIVVKDVFVPRHRFLSYKAMNDGTAGGYAT
TH_1742|M.thermoresistible__bu --YTIDDVWHVVGLRGTGSNTIVVKDVFVPRHRFLSYKAMNDGTAGGYRT
MAB_0584|M.abscessus_ATCC_1997 --YRIDDVWNVVGLRGTGSNTVVVKDVFVPKHRFLSYKKMNDQTAGGYQT
MLBr_00737|M.leprae_Br4923 EGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATLD
: * :*::.: :. : ... :* .*::. . ** .
Mb3601c|M.bovis_AF2122/97 NSAPVYKMPWGTMHPTTISAPIVGMAYGAYAAHVEHQGKRVRAAFAGEKA
Rv3570c|M.tuberculosis_H37Rv NSAPVYKMPWGTMHPTTISAPIVGMAYGAYAAHVEHQGKRVRAAFAGEKA
MMAR_5065|M.marinum_M NTAPVYKMPWGTMHPTTITAPIVGMAYGAYDAHVEHQGKRVRAAFAGEKA
MUL_4141|M.ulcerans_Agy99 NTAPVYKMPWGTMHPTTITAPIVGMAYGAYDAHVEHQGKRVRAAFAGEKA
MAV_0591|M.avium_104 NTAPVYKMPWGTMHPTTISAPIVGMAYGAYAAHVEHQGKRVRAAFAGEKA
Mvan_5308|M.vanbaalenii_PYR-1 NTAPVYKMPWGTMHPTTISAPIMGMAYGAYDAHVEHQGKRVRAAFAGEKS
Mflv_1463|M.gilvum_PYR-GCK NTAPVYKMPWGTMHPTTISAPIMGMAYGAYEAHVEHQGKRVRAAFAGEKS
MSMEG_6038|M.smegmatis_MC2_155 NTAPVYKMPWGTVHPTTISAPIVGMAYGAYAAHVEHQGKRVRAAFAGEKS
TH_1742|M.thermoresistible__bu NTAPVYRMPWGTVHPTTISAPIVGMAYGAYQAHVEHQGKRVRAAYAGEKA
MAB_0584|M.abscessus_ATCC_1997 NTAPVYKMPWGTMHPTTITAPIMGMAYGAYDAHVEAQGKRVRAAYAGEKA
MLBr_00737|M.leprae_Br4923 HTRP------------TIGAQAVGIAQGALDAAIVYTKDRK---QFGESI
:: * ** * :*:* ** * : .* **.
Mb3601c|M.bovis_AF2122/97 KDDPFAKVRIAEAASDIDAAWRQLIGNVSDEYALLAAGKEIPFELRARAR
Rv3570c|M.tuberculosis_H37Rv KDDPFAKVRIAEAASDIDAAWRQLIGNVSDEYALLAAGKEIPFELRARAR
MMAR_5065|M.marinum_M KDDPFAKVRIAEAASDIDAAWRQLMGNVGDEYALLSAGKEIPFDLRTRAR
MUL_4141|M.ulcerans_Agy99 KDDPFAKVRIAEAASDIDAAWRQLMGNVGDEYALLSAGKEIPFDLRTRAR
MAV_0591|M.avium_104 KDDPFAKVRIAEAASDIDAAWRQLSGNVADEYALLSAGKEIPFELRARAR
Mvan_5308|M.vanbaalenii_PYR-1 KDDPFAKIRIAEAASDIDAGWRQLIGNVGAEYRLLEAGEEIPFSLRAAAR
Mflv_1463|M.gilvum_PYR-GCK KDDPFAKIRIAEAASDIDAGWRQLIGNVRDEYELLQAGKEIPFSLRASAR
MSMEG_6038|M.smegmatis_MC2_155 KDDPFAKVRIAEAASDIDAAWRQLIGNVGEEYELLKAGKEIPFDLRARAR
TH_1742|M.thermoresistible__bu KDDPFAKIRIAEAASDIDAAWRQLIGNVGDEYALLKAGKEIPFELRARAR
MAB_0584|M.abscessus_ATCC_1997 KDDPFTKVRVAEAASDIDAGWRQLIGNVGDEYALIAAGQEVPFELRAAAR
MLBr_00737|M.leprae_Br4923 STFQSIQFMLADMAMKVEAAR-------LIVYAAAARAERGEPDLGFISA
. :. :*: * .::*. * .:. .* :
Mb3601c|M.bovis_AF2122/97 RDQVRATGRSIASIDRLFEASGATALSNEAPIQRFWRDAHAGRVHAANDP
Rv3570c|M.tuberculosis_H37Rv RDQVRATGRSIASIDRLFEASGATALSNEAPIQRFWRDAHAGRVHAANDP
MMAR_5065|M.marinum_M RDQVRATGRSIASIDRLFEASGATALANDAPIQRFWRDAHAGRVHAANDP
MUL_4141|M.ulcerans_Agy99 RDQVRATGRSIASIDRLFEASGATALANDAPIQRFWRDAHAGRVHAANDP
MAV_0591|M.avium_104 RDQVRATGRAIASIDRLFEASGATALANDQPVQRFWRDAHAGRVHAANDP
Mvan_5308|M.vanbaalenii_PYR-1 RDQVRATARAIASIDLLFEASGATALQLDQPVQRFWRDAHAGRVHAANEP
Mflv_1463|M.gilvum_PYR-GCK RDQVRATARAIASIDLLFEASGATALQLDQPVQRFWRDAHAGRVHAANEP
MSMEG_6038|M.smegmatis_MC2_155 RDQVRATGRAIASIDLLFESAGATALINTAPLQRFWRDAHAGRVHAANEP
TH_1742|M.thermoresistible__bu RDQVRATGRAIASIDRLFEASGATALQNTAPIQRFWRDAHAGRVHAANDP
MAB_0584|M.abscessus_ATCC_1997 RDQVRATGRAIASIDLLFENSGATALSNDAPVQRFWRDAHAGRVHAANDA
MLBr_00737|M.leprae_Br4923 ASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTN-
.: *: :: .: *.:. *::** ***: ::: ..:
Mb3601c|M.bovis_AF2122/97 ERAYVIFGNHEFGLPPGDTMV
Rv3570c|M.tuberculosis_H37Rv ERAYVIFGNHEFGLPPGDTMV
MMAR_5065|M.marinum_M ERAYVIFGNNEFGLPAGDTMV
MUL_4141|M.ulcerans_Agy99 ERAYVIFGNNEFGLPAGDTMV
MAV_0591|M.avium_104 ERAYQIFGNHEFGLPPGDTMV
Mvan_5308|M.vanbaalenii_PYR-1 ERAYLIFGNDAFGLPPQDTMV
Mflv_1463|M.gilvum_PYR-GCK ERAYLIFGNDAFGLPPQDTMV
MSMEG_6038|M.smegmatis_MC2_155 ERAYLIFGNHEFGLPPADTMV
TH_1742|M.thermoresistible__bu ERAYLIFGNHEFGLPPQDTMV
MAB_0584|M.abscessus_ATCC_1997 ERAYQIWGNHAFELPATDTMV
MLBr_00737|M.leprae_Br4923 QIQRVVMSRALLR--------
: : .. :