For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VIVTGGAGVIGQAICRRLLQSDYVPVAADLKPAVDQLDLTQENMTGALKVAMDVSDRESVQSAVDSVVED GDTLYGLVNCAGILRDSFLGELDEAKLELMFQVNIAGMARVTDAVAPHLREGSAIVNIGSLTGHFGRFRG ASVYGATKAGIAAYTRYLAEELAPRGIRVNNIAPGVIRAPMSPSMARVSGGEEISASYAMLKRIGEPEEV AEAVEFMLSPRASFITAQTLLVDGGVVAW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3823 | - | - | 100% (239) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_2566 | - | 7e-29 | 36.71% (237) | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3830 | - | 8e-28 | 33.74% (243) | 3-oxoacyl- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1385 | fabG | 8e-26 | 33.89% (239) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4104 | - | 4e-29 | 36.86% (236) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1350 | fabG | 8e-26 | 33.89% (239) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_02565 | fabG | 8e-24 | 30.42% (240) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. abscessus ATCC 19977 | MAB_0827 | - | 4e-30 | 34.71% (242) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_0402 | - | 3e-28 | 37.92% (240) | short chain dehydrogenase |
| M. avium 104 | MAV_5120 | - | 1e-28 | 37.82% (238) | oxidoreductase |
| M. thermoresistible (build 8) | TH_2925 | - | 1e-25 | 33.61% (241) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_1052 | - | 6e-27 | 37.08% (240) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0607 | - | 1e-113 | 86.19% (239) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3823|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0607|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0402|M.marinum_M --------------------------------------------------
MUL_1052|M.ulcerans_Agy99 --------------------------------------------------
MAV_5120|M.avium_104 --------------------------------------------------
Mflv_4104|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0827|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1385|M.bovis_AF2122/97 --------------------------------------------------
Rv1350|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02565|M.leprae_Br4923 MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI
TH_2925|M.thermoresistible__bu --------------------------------------------------
MSMEG_3823|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0607|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0402|M.marinum_M --------------------------------------------------
MUL_1052|M.ulcerans_Agy99 --------------------------------------------------
MAV_5120|M.avium_104 --------------------------------------------------
Mflv_4104|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0827|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1385|M.bovis_AF2122/97 --------------------------------------------------
Rv1350|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02565|M.leprae_Br4923 GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK
TH_2925|M.thermoresistible__bu --------------------------------------------------
MSMEG_3823|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0607|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0402|M.marinum_M --------------------------------------------------
MUL_1052|M.ulcerans_Agy99 --------------------------------------------------
MAV_5120|M.avium_104 --------------------------------------------------
Mflv_4104|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0827|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1385|M.bovis_AF2122/97 --------------------------------------------------
Rv1350|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02565|M.leprae_Br4923 GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK
TH_2925|M.thermoresistible__bu --------------------------------------------------
MSMEG_3823|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0607|M.vanbaalenii_PYR-1 --------------------------------------M-----------
MMAR_0402|M.marinum_M -------------------------------MTGG---------------
MUL_1052|M.ulcerans_Agy99 -------------------------------MTGG---------------
MAV_5120|M.avium_104 -------------------------------MTGGSAQP-----------
Mflv_4104|M.gilvum_PYR-GCK -------------------------------MAAD---------------
MAB_0827|M.abscessus_ATCC_1997 -------------------------------MTSPLK-------------
Mb1385|M.bovis_AF2122/97 ---------------------------MASLLNAR---------------
Rv1350|M.tuberculosis_H37Rv ---------------------------MASLLNAR---------------
MLBr_02565|M.leprae_Br4923 ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD
TH_2925|M.thermoresistible__bu -------------------------------MSSEVVP------------
MSMEG_3823|M.smegmatis_MC2_155 ---------------MIVTGGAGVIGQAICRRLLQSDYVPVAADLKPAVD
Mvan_0607|M.vanbaalenii_PYR-1 ------------GNKVIVTGGAGVIGQAICRRLLQGGYVPVAADLKQAVD
MMAR_0402|M.marinum_M ------------GRVALVTGAAGGQGWAIVQRLRAEGHSVAACDLRADRL
MUL_1052|M.ulcerans_Agy99 ------------GRVALVTGAAGGQGWAIVQRLRAEGHSVAACDLRADRL
MAV_5120|M.avium_104 ------------PRVALVTGAAGGQGRAIAERLRGNGFAVAACDRRIDEL
Mflv_4104|M.gilvum_PYR-GCK -------------RIALVTGAARGQGAAIVTRLLQDGFRVAACDLLGDDV
MAB_0827|M.abscessus_ATCC_1997 ------------SRRAFVTGGSRGIGAGIVRRLAEDGARVVFTYSSSVQQ
Mb1385|M.bovis_AF2122/97 --------------TAVITGGAQGLGLAIGQRFVAEGARVVLGDVN--LE
Rv1350|M.tuberculosis_H37Rv --------------TAVITGGAQGLGLAIGQRFVAEGARVVLGDVN--LE
MLBr_02565|M.leprae_Br4923 STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVESAAE
TH_2925|M.thermoresistible__bu --------------VAVVTGGARGIGEAIAAALIDAGYRTAVIDVN-EKA
.:**.: * .* . . .
MSMEG_3823|M.smegmatis_MC2_155 QLDLTQENMTG---ALKVAMDVSDRESVQSAVDSVVEDGDT-LYGLVNCA
Mvan_0607|M.vanbaalenii_PYR-1 AVDFGQAGLQG---TLSVAMDVTDRASVDEAVASTVDDGET-LFGLVNCA
MMAR_0402|M.marinum_M DALVAESGDDA---VISLALDVTDEAQWQEAVERAVTRFGA-LTALINNA
MUL_1052|M.ulcerans_Agy99 DALVAESGDDA---VISLALDVTDEAQWQEAVERAVTRFGA-LTALINNA
MAV_5120|M.avium_104 AATVAASGDDR---LIAVELDVTSEQQWRSAVERVVDRFGA-LSALVNCA
Mflv_4104|M.gilvum_PYR-GCK TRTVAAHDTDH---AVAIELDVTSAEQWTRAVGEVVDRFGG-LSTLVNNA
MAB_0827|M.abscessus_ATCC_1997 AADVVDDINEDGGWARAVKADVADPDQLGAAIGQAAEELGG-LDILVNNA
Mb1385|M.bovis_AF2122/97 ATEVAAKRLGGDDVALAVRCDVTQADDVDILIRTAVERFGG-LDVMVNNA
Rv1350|M.tuberculosis_H37Rv ATEVAAKRLGGDDVALAVRCDVTQADDVDILIRTAVERFGG-LDVMVNNA
MLBr_02565|M.leprae_Br4923 ALDETANRVGGTTLSL----DVTADDAVDKITEHLHDYQGGHADILVNNA
TH_2925|M.thermoresistible__bu ITRAADSDAARQGKLIPLQLSITDRPAVERAMGELADAHGP-IRALVNNA
.:: ::* *
MSMEG_3823|M.smegmatis_MC2_155 GILRDSFLGELDEAKLELMFQVNIAGMARVTDAVAPHLR--EGSAIVNIG
Mvan_0607|M.vanbaalenii_PYR-1 GILRDSFLGELDEAKLDLMFQVNIAGMARVTDAVAPLLT--EGSAIVNVG
MMAR_0402|M.marinum_M GVLHRAALVDETAAGFESAWRVNCLGAFLGMRAALGALSAAEGPVIVNIC
MUL_1052|M.ulcerans_Agy99 GVLHRAALVDETAAGFESAWRVNCLGAFLGMRAALGALSAAEGPVIVNIC
MAV_5120|M.avium_104 GVLHRTPLPQETADAFENAWRVNCFGAFLGMRAALERLRGTPGASIVNIC
Mflv_4104|M.gilvum_PYR-GCK GVLHRASLADETPDGFEGSWRVNSLGPFLGIQAALPHLKAAEGAAIVNTC
MAB_0827|M.abscessus_ATCC_1997 GILSIGDVDTATLADFDEIVAVNVRAVFAGIKAASPHLT--EGGRIVTIG
Mb1385|M.bovis_AF2122/97 GITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRGAIVNMS
Rv1350|M.tuberculosis_H37Rv GITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRGAIVNMS
MLBr_02565|M.leprae_Br4923 GITRDKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSISKGGRVIVLS
TH_2925|M.thermoresistible__bu GMTLPGSFLDQTDEDWDRIVDVNLKGTFVMSQVVARQMVEERTGAIVNIS
*: . : *: . ::
MSMEG_3823|M.smegmatis_MC2_155 SLTGHFGRFRGASVYGATKAGIAAYTRYLAEELAPRGIRVNNIAPGVIRA
Mvan_0607|M.vanbaalenii_PYR-1 SLTGHFGRFRGASVYGATKAGIAAYTRYVAEELASRSVRVNNVAPGVIRA
MMAR_0402|M.marinum_M ST-GAIRPFPHHCAYGAAKWALRGLTQTAAAELAPAGIRVNAVFPGPIAT
MUL_1052|M.ulcerans_Agy99 ST-GAIRPFPHHCAYGAAKWALRGLTQTAAAELAPAGFRVNAVFPGPIAT
MAV_5120|M.avium_104 ST-GAIRPFPQHCAYGSSKWALRGLTQTAAAELAPAGIRVNAVFPGPIAT
Mflv_4104|M.gilvum_PYR-GCK ST-GAIRPFPNHAAYGSSKWALRGLTQVAAVELAPSGIRVNAVFPGPVET
MAB_0827|M.abscessus_ATCC_1997 SINGDSSPTANLSLYSMTKAAVAGLTRGLAREFGPRGITINNVQPGPIGT
Mb1385|M.bovis_AF2122/97 SVSGKVG-MVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAPGLIRS
Rv1350|M.tuberculosis_H37Rv SVSGKVG-MVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAPGLIRS
MLBr_02565|M.leprae_Br4923 SMAGIAG-NRGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPGFIET
TH_2925|M.thermoresistible__bu SVSAHGV-RTGPPAYAAAKAGVEGLSRLMAVQLGPSGIRVNTVVVGTTAT
* . *. :* .: . :: * :. .. :* : * :
MSMEG_3823|M.smegmatis_MC2_155 PMSPSMARVSGGEEISASYAMLKRIGEPEEVAEAVEFMLSPRASFITAQT
Mvan_0607|M.vanbaalenii_PYR-1 PMSPSMARVSGGEEVSASYAMLKRIGEPEEVAEAVEFLLSPRASFITAQT
MMAR_0402|M.marinum_M SMLDEPTQAR-----LAAVSMFGRLGRPAEVADAVAFLVSENSSFITGSE
MUL_1052|M.ulcerans_Agy99 SMLDEPTQAR-----LAAVSMFGRLGRHAEVADAVAFLVSENSSFITGSE
MAV_5120|M.avium_104 PMLDEATQTR-----LAAAASFGRIGQPGEVADAVAFLVSAEASFITGAE
Mflv_4104|M.gilvum_PYR-GCK PMLDANTQTR-----LAANALMGRIGKPMEIADAVAFLVSEHATFITGSE
MAB_0827|M.abscessus_ATCC_1997 DMNPEDGQLAD---ILRPNIAVGRYGQPRDIASLVSYLVSDEAWYITGTA
Mb1385|M.bovis_AF2122/97 AMTEAMPQRIWDQK-LAEVPMG-RAGEPSEVASVAVFLASDLSSYMTGTV
Rv1350|M.tuberculosis_H37Rv AMTEAMPQRIWDQK-LAEVPMG-RAGEPSEVASVAVFLASDLSSYMTGTV
MLBr_02565|M.leprae_Br4923 QMTAAIPLATREVG-RRLNSLL-QGGLPVDVAETIAYFAIPASNAVTGNV
TH_2925|M.thermoresistible__bu PWLLSRKTDEELAT-MRESTLLDRLGEPEDVAATVAFLCSPAARHVTGQL
: * ::* :: : :*.
MSMEG_3823|M.smegmatis_MC2_155 LLVDGGVVAW--
Mvan_0607|M.vanbaalenii_PYR-1 LLVDGGVVAW--
MMAR_0402|M.marinum_M LVVDGGQCLQVP
MUL_1052|M.ulcerans_Agy99 LVVDGGQCLQVP
MAV_5120|M.avium_104 LVVDGGQCLQIR
Mflv_4104|M.gilvum_PYR-GCK LIVDGGQSLQIG
MAB_0827|M.abscessus_ATCC_1997 INIDGGFTA---
Mb1385|M.bovis_AF2122/97 LDVTGGRFI---
Rv1350|M.tuberculosis_H37Rv LDVTGGRFI---
MLBr_02565|M.leprae_Br4923 IRVCGQAMLGA-
TH_2925|M.thermoresistible__bu VSVSGGQWMP--
: : *