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VSVVAEHSTIAHTSLGTLRGTLEAGVSVWRGVHYAQQPVGDLRFRAPQPLQPWSGVREAVEHGPLPPQGR SFVGGGRDDPKMRDEACLTVTVWSPDTSGALPVMVWIPGGAFVYGAGQLQLYNGSRLAANGNVVVVNVTY RLGVFGGFELGDLAGDFSDNLCLRDQLAALQWVRDNIAAFGGDPKRVTVFGESAGATSVLALLASPSAEG LFARAIAQSPALPLIADRDVRARQAHRFLEIVGEDPAKLRDLPQKQLRRAAGQVQLESAQHTPTLAYGLT HGVDLLPRHPIDAARAGEVLPVPLIIGTNSHEASMFAWGKPPMLPTTVAGVEHYFRRKHAGAKDRILSAY PAFPRRRALVAFGSDVMFGAPTWAFSDAYSAHAPTHVYRFDHTTWTLRALGLGATHGSEIVHIQHSYGSY LGRRLHPLGRHVQPSVGRRMQRTWLDFARAEIADWPFYDTERRLTRVIRSTRDDTVADPDALRRAVWEGL Y
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3002 | - | - | 100% (491) | para-nitrobenzyl esterase |
| M. smegmatis MC2 155 | MSMEG_3848 | - | 8e-96 | 42.08% (499) | para-nitrobenzyl esterase |
| M. smegmatis MC2 155 | MSMEG_3667 | - | 4e-83 | 38.75% (511) | para-nitrobenzyl esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2071c | lipT | 2e-86 | 38.46% (507) | carboxylesterase LipT |
| M. gilvum PYR-GCK | Mflv_3787 | - | 0.0 | 70.91% (495) | carboxylesterase, type B |
| M. tuberculosis H37Rv | Rv2045c | lipT | 2e-86 | 38.46% (507) | carboxylesterase LipT |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2866c | - | 0.0 | 68.10% (489) | carboxylesterase (LipT) |
| M. marinum M | MMAR_3020 | lipT | 2e-86 | 38.65% (502) | carboxylesterase, LipT |
| M. avium 104 | MAV_2466 | - | 1e-89 | 40.56% (498) | LppT protein |
| M. thermoresistible (build 8) | TH_2744 | - | 0.0 | 72.60% (500) | PUTATIVE Carboxylesterase, type B |
| M. ulcerans Agy99 | MUL_2261 | lipT | 4e-86 | 38.65% (502) | carboxylesterase, LipT |
| M. vanbaalenii PYR-1 | Mvan_2609 | - | 0.0 | 70.58% (486) | carboxylesterase, type B |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2071c|M.bovis_AF2122/97 -----------------------MALESATVGSMHERTVRARTATGIVEG
Rv2045c|M.tuberculosis_H37Rv -----------------------MALESATVGSMHERTVRARTATGIVEG
MAV_2466|M.avium_104 ---------------------------------MHDRTVRARTATGIVEG
MMAR_3020|M.marinum_M ---------------------------------MHERTVRARTATGIVEG
MUL_2261|M.ulcerans_Agy99 ---------------------------------MHERTVRARTATGVVEG
MSMEG_3002|M.smegmatis_MC2_155 ------------------------------MSVVAEHSTIAHTSLGTLRG
TH_2744|M.thermoresistible__bu ----VVLVSMRIPSLKVMG--SASHNYHAGVTAVVERSPIADTPLGRLRG
Mflv_3787|M.gilvum_PYR-GCK ------------------------------MAIVDGDSTLVSTPSGDLRG
Mvan_2609|M.vanbaalenii_PYR-1 ---------------------------------------MLSTPSGDLRG
MAB_2866c|M.abscessus_ATCC_199 MYPEKTRGNFPAPPLRLCGPVTADRTTIRYVAVDVALPTVVRTPLGALRG
*. * :.*
Mb2071c|M.bovis_AF2122/97 FTR-------DGVHRWRSIPYARAPVGSLRFRAPQPAQPWPGVRHCHTFA
Rv2045c|M.tuberculosis_H37Rv FTR-------DGVHRWRSIPYARAPVGSLRFRAPQPAQPWPGVRHCHTFA
MAV_2466|M.avium_104 FTR-------DGVHRWRSIPYARPPVGDLRFRAPQPAQPWSGVRHCHGFA
MMAR_3020|M.marinum_M FTR-------DGVHRWRSIPYARAPIGPLRFRAPRPPQPWSGVRHCHGFT
MUL_2261|M.ulcerans_Agy99 FTR-------DGVHRWRSIPYARAPIGLLRFRAPRPPQPWSGVRHCHGFT
MSMEG_3002|M.smegmatis_MC2_155 TLE-------AGVSVWRGVHYAQQPVGDLRFRAPQPLQPWSGVREAVEHG
TH_2744|M.thermoresistible__bu SYENVPAQAAEGVAVWRGVPYARQPVGDLRFRAPEPPRPWSGVRDAVEPA
Mflv_3787|M.gilvum_PYR-GCK DID-------GGVGVWRGVPYAEQPVGLRRFLAPAELAPWMGVRDAVEHG
Mvan_2609|M.vanbaalenii_PYR-1 EVE-------AGIGVWRGIPYAEQPTGQRRFLAPEPMAPWPGVREAREHG
MAB_2866c|M.abscessus_ATCC_199 AIE-------GGVSVWRGVPYAQQPVEQLRFLAPVPLEPWEGVRDAIEHA
*: **.: **. * ** ** ** ***..
Mb2071c|M.bovis_AF2122/97 NCAPQQRRYTVMGIG----RYQTRSEDCLTLNVVTPEEPATQPLPVMVFI
Rv2045c|M.tuberculosis_H37Rv NCAPQQRRYTVMGIG----RYQTRSEDCLTLNVVTPEEPATQPLPVMVFI
MAV_2466|M.avium_104 NCAPQQRRYTLLGLSGLGGRYQPMSEDCLTLNVVTPEAPAEGPLPVMVFI
MMAR_3020|M.marinum_M HCSPQQRRYTMLGLG----KYQPMSEDCLTLNVVAPEAPSHRPLPVMVFI
MUL_2261|M.ulcerans_Agy99 HCSPQQRRYTMLGLG----KYQPMSEDCLTLNVVAPEAPTHRPLPVMVFI
MSMEG_3002|M.smegmatis_MC2_155 PLPPQGRSFVGGGRD----DPKMRDEACLTVTVWSPD--TSGALPVMVWI
TH_2744|M.thermoresistible__bu PIPPQGRSFVGGGKD----DPRIRDEACLTLTVWSPD--PGGSLPVMVWI
Mflv_3787|M.gilvum_PYR-GCK PLPPQTKSFVGGGRD----DPKARDEACLTLTVWSPD--TTGSLPVMVWI
Mvan_2609|M.vanbaalenii_PYR-1 PLPPQSKSFVGGGRD----DPKVRDEACLTLTVWSPD--TAASLPVMVWI
MAB_2866c|M.abscessus_ATCC_199 PLPPQGKSFVGAGRD----DPKIRGEECLTVTVWSPD--VHASLPVMVWI
.** : :. * . : .* ***:.* :*: .*****:*
Mb2071c|M.bovis_AF2122/97 HGGGYILGSSATPIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPQ
Rv2045c|M.tuberculosis_H37Rv HGGGYILGSSATPIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPQ
MAV_2466|M.avium_104 HGGGYFLGSSATPLYDGAALARRG-CVYVSVNYRLGALGCVDFSSLSTPE
MMAR_3020|M.marinum_M HGGGYILGSSATPIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPD
MUL_2261|M.ulcerans_Agy99 HGGGYILGSSATPIYDGAALARRG-CVYVSVNYRLGALGCLDLSSLSTPD
MSMEG_3002|M.smegmatis_MC2_155 PGGAFVYGAGQLQLYNGSRLAANGNVVVVNVTYRLGVFGGFELGDLAG--
TH_2744|M.thermoresistible__bu PGGAFVYGAGHLQLYNGSRLAANGNVVVVNVTYRLGVFGGFELSGLGA--
Mflv_3787|M.gilvum_PYR-GCK PGGAFVYGAGQFQLYNGSRLAANGDVVVVNVTYRIGVFGGFELSDLGE--
Mvan_2609|M.vanbaalenii_PYR-1 PGGAFVYGAGQFQLYNGSRLAANGDVVVVNVTYRIGVFGGLELSDLGD--
MAB_2866c|M.abscessus_ATCC_199 PGGAFVFGAGQLELYSGARLAANGNVVVVNVTYRLGALGGLELSALGE--
**.:. *:. :*.*: ** .* * *.*.**:*.:* .::. *.
Mb2071c|M.bovis_AF2122/97 ITLDSNVYLRDLVLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATLLA
Rv2045c|M.tuberculosis_H37Rv ITLDSNVYLRDLVLALRWVHDNIAEFGGDPGNVTIFGESAGAHITATLLA
MAV_2466|M.avium_104 IPLESNLYLRDLVLALQWVRDNIAEFGGDPDNVTIFGESAGACITATLLA
MMAR_3020|M.marinum_M IAIDGNLYLRDLVMALQWIQDNIAEFGGDPDNVTIFGESAGAHITATLLA
MUL_2261|M.ulcerans_Agy99 IAIDGNLYLRDLVMALQWIQDNIAEFGGDPDNVTIFGESAGAHITATLLA
MSMEG_3002|M.smegmatis_MC2_155 -DFSDNLCLRDQLAALQWVRDNIAAFGGDPKRVTVFGESAGATSVLALLA
TH_2744|M.thermoresistible__bu -GFDDNLALRDQVAALRWVRDNIAAFGGDPGRVTVFGESAGATSVLALLA
Mflv_3787|M.gilvum_PYR-GCK -GFDDNLALRDQIAALRWVRDNIAAFGGDPGRVTVFGESAGATSVLALMA
Mvan_2609|M.vanbaalenii_PYR-1 -GFDDNLALRDQIAALRWVRDNISAFGGDPGRVTVFGESAGATSVLALMA
MAB_2866c|M.abscessus_ATCC_199 -GFDDNLALRDQMAALTWVRDNIAAFGGDPDHVTIFGESAGATSVLALLA
:..*: *** : ** *::***: ***** .**:******* . :*:*
Mb2071c|M.bovis_AF2122/97 VPAAKGLFARAISESPAAGMVRSREVAAEFAARFANLIGARTQDAANALM
Rv2045c|M.tuberculosis_H37Rv VPAAKGLFARAISESPAAGMVRSREVAAEFAARFANLIGARTQDAANALM
MAV_2466|M.avium_104 VPAAKGLFAQAISESPASGLVRSQEVAAEFANRFANLLGVRRQDAANALM
MMAR_3020|M.marinum_M VPAAKGLFARAISESPAAGMVRPREIAAEFATRFARLLGARKHDAASALM
MUL_2261|M.ulcerans_Agy99 VPAAKGLFARAISESPAAGMVRPREIAAEFATRFARLLGARKHDAASALM
MSMEG_3002|M.smegmatis_MC2_155 SPSAEGLFARAIAQSPALPLIADRDVRARQAHRFLEIVGE-----DPAKL
TH_2744|M.thermoresistible__bu SPAARGLFHRAIAQSPALPLIADADLRAGRAARFVERLGV-----GVDDI
Mflv_3787|M.gilvum_PYR-GCK APSATGLFGRAIAQSPALPLIADRHLRAANAQEFLRRLGV-----DAAEV
Mvan_2609|M.vanbaalenii_PYR-1 APSAQRLFHRAIAQSPALPLVADREYRAANAHEFLRRLGV-----GAGEV
MAB_2866c|M.abscessus_ATCC_199 SPAAEGLFGRAIAQSPALPLIADKALRDKRAHRYLELLDVT----DPSRL
*:* ** :**::*** :: * .: . :. :
Mb2071c|M.bovis_AF2122/97 QASPAQLVEAQHHLIRQGMRKRLGAFPIGPVFGDDYLPMDPVEAMRSGRV
Rv2045c|M.tuberculosis_H37Rv QASPAQLVEAQHHLIRQGMRKRLGAFPIGPVFGDDYLPMDPVEAMRSGRV
MAV_2466|M.avium_104 QASAAQLVKTQHRLIDEGMQDRLGAFPIGPVVGDDILPTDPVEAMRRGEA
MMAR_3020|M.marinum_M RATAAQLVQTQHRLIDQGMQKRLGAFPIGPTFGDDCLPLDPVEAMRAGQS
MUL_2261|M.ulcerans_Agy99 RATAAQLVQTQHRLIDQGMQKRLGAFPIGPTFGDDCLPLDPVEAMRAGQS
MSMEG_3002|M.smegmatis_MC2_155 RDLPQKQLRRAAGQVQLESAQHTPTLAYGLTHGVDLLPRHPIDAARAGEV
TH_2744|M.thermoresistible__bu RELPQRALRRAAGLVQLDSIADSPALAYGLTHGVDLLPRHPIAAARAGTV
Mflv_3787|M.gilvum_PYR-GCK KTLPQRQLRRAAGLVQLTSAATTPTLAYGLTTGTDLLPLHPLDAARQGRM
Mvan_2609|M.vanbaalenii_PYR-1 KALPQRQLRRAAGILQLKSAANTPTLAYGLTYGTELLPQHPVAAAREGRT
MAB_2866c|M.abscessus_ATCC_199 KVLPQRELRRGAAKLQIESATETPVLGYGLAHGTELLPYHPIEAARRGEV
: . : :. : .: * . * : ** .*: * * *
Mb2071c|M.bovis_AF2122/97 HAVPLIVGTNAEEGRLFTR-FLGMLPTNEPMVEELLSGMKPADRERITAA
Rv2045c|M.tuberculosis_H37Rv HAVPLIVGTNAEEGRLFTR-FLGMLPTNEPMVEELLSGMKPADRERITAA
MAV_2466|M.avium_104 HRVPLIVGTNAEEGRLFTR-FLAMLPTNESMVEELLADAEPAVRERITAA
MMAR_3020|M.marinum_M HKVPLIVGTNADEGRLFTR-FLKMLPTNKAMIDELLADTEPATRERITAA
MUL_2261|M.ulcerans_Agy99 HKVPLIVGTNADEGRLFTR-FLKMLPTNKAMIDELLADTEPATRERITAA
MSMEG_3002|M.smegmatis_MC2_155 LPVPLIIGTNSHEASMFAWGKPPMLPTTVAGVEHYFRRKHAGAKDRILSA
TH_2744|M.thermoresistible__bu HPVPLIIGTNSDEASMFAWGRPPMLPTTPDRVEHYFRRHAPHARDTVLAA
Mflv_3787|M.gilvum_PYR-GCK SSVPLIVGTNSHEASMFAWTKPPMLPTTRESIDGFFERTAPHAKRQVLQA
Mvan_2609|M.vanbaalenii_PYR-1 SGVPLIIGTNSHEASMFAWTKPPMLPTTKASIDGYFQRVAPDAKQRVLQA
MAB_2866c|M.abscessus_ATCC_199 HQVPLIIGSNSHEASMFARVKPPMLPTTEPTVNGYFNRIGPEYQDAIIAA
****:*:*:.*. :*: ****. :: : . : : *
Mb2071c|M.bovis_AF2122/97 YPNYPAPSACIQLGGDFAFSSAAWQIAEAHGANAPTYLYRYDYAPRTLRW
Rv2045c|M.tuberculosis_H37Rv YPNYPAPSACIQLGGDFAFSSAAWQIAEAHGANAPTYLYRYDYAPRTLRW
MAV_2466|M.avium_104 YPDYPDRSACIQLGGDFAFGSAAWQIAEAHCAHAPTYLYRYDYAPRTLRW
MMAR_3020|M.marinum_M YPNYPESAACIQLGGDFAFNAAAWQIAEAQGAHAPTYLYRYDYAPRTLRW
MUL_2261|M.ulcerans_Agy99 YPNYPESAACIQLGGDFAFNAAAWQIAEAQGVHAPTYLYRYDYAPRTLRW
MSMEG_3002|M.smegmatis_MC2_155 YPAFPRRRALVAFGSDVMFGAPTWAFSDAYSAHAPTHVYRFDHTTWTLRA
TH_2744|M.thermoresistible__bu YPGYPRRRAAVAVGADVMFAAPTWAFADAYSAHAPTYLYRFEHAPPALRA
Mflv_3787|M.gilvum_PYR-GCK YPGYPRRSALVAIGADAMFGGPTWAFADAYSAHAPTRMYRFDHFGMSLRM
Mvan_2609|M.vanbaalenii_PYR-1 YPGYPRRSALVALGSDAMFGGPTWAFADAYSALAPTRMYRFDHFGWSLRM
MAB_2866c|M.abscessus_ATCC_199 YPGYPSRQALVAVGSDAMFAAPMWAFADAYSAFVDTYMYRFDHTAWGLKL
** :* * : .*.* * .. * :::* . . * :**::: *:
Mb2071c|M.bovis_AF2122/97 SGFGATHATELFAVFDIYRTRFGALLTAAADRRAALRVSNEVQRRWRCFS
Rv2045c|M.tuberculosis_H37Rv SGFGATHATELFAVFDIYRTRFGALLTAAADRRAALRVSNEVQRRWRCFS
MAV_2466|M.avium_104 SGFGATHATELLAVFDVYRTRFGALLTAAADRRAALRVSNQVQRRWRAFS
MMAR_3020|M.marinum_M SGFGATHATELFAVFDIYRTRFGALLTAAADRRHALRVSDEVIRRWRSFS
MUL_2261|M.ulcerans_Agy99 SGFGATHATELFAVFDIYRTRFGALLTAAADRRHALRVSDEVIRRWRSFS
MSMEG_3002|M.smegmatis_MC2_155 LGLGATHGSEIVHIQHSYGSYLGRRLHPLG-RHVQPSVGRRMQRTWLDFA
TH_2744|M.thermoresistible__bu LGLGATHGSEIVHIQHTYASYPGRRLHPLG-ARRTPAVGRRMQRAWLAFA
Mflv_3787|M.gilvum_PYR-GCK LGLGATHGSEIVHIHHSYASFVGRKLHPLG-RRIQPGVGRRMQRSWLDFA
Mvan_2609|M.vanbaalenii_PYR-1 LGLGATHGSEIVHIHHSYESFVGRKLHPLG-RRIQPGVGRRMQRAWLDFA
MAB_2866c|M.abscessus_ATCC_199 LGLGATHGSEIVHVQHSYGSFVGMLLSPLG-ARMMPSVGRRMQRAWLDFA
*:****.:*:. : . * : * * . . : *. .: * * *:
Mb2071c|M.bovis_AF2122/97 Q--IGVPGDDWPAYTQDDR-AVLVFDRRCRIEFDPHQHRRIAWDGFSLAN
Rv2045c|M.tuberculosis_H37Rv Q--IGVPGDDWPAYTQDDR-AVLVFDRRCRIEFDPHQHRRIAWDGFSLAN
MAV_2466|M.avium_104 R--TGVPGEDWPRYTAADR-AVLVFDRKSRVEFDPHPHRRMAWDGFSLAR
MMAR_3020|M.marinum_M Q--TGTPGEDWPAYTHTRR-AVMVIDRKSRVEIDPHQHRRLAWDGFSLAR
MUL_2261|M.ulcerans_Agy99 Q--TGTPGEDWPAYTHTRR-AVMVIDRKSRVEIDPHRHRRLAWDGFSLAR
MSMEG_3002|M.smegmatis_MC2_155 R--AEIA--DWPFYDTERRLTRVIRSTRDDTVADPDALRRAVWEGLY---
TH_2744|M.thermoresistible__bu T--DDHPGSDWPRYDTGRRRTRLIRTGEDLVADDPDVVRRTAWQGVY---
Mflv_3787|M.gilvum_PYR-GCK RDNAEVDEGHWPLYEIGARLTRLITSTRDVMASDPDRDRREAWAQVYQPP
Mvan_2609|M.vanbaalenii_PYR-1 RGSEDVDDEHWPLYETGERLTRLIASTRDVMASDPDRDRRQAWAAVY---
MAB_2866c|M.abscessus_ATCC_199 T---GAGPEDWPTYGADGRRTRIIRSRSDVTVEDPDSVRRIAWAQVH---
.** * * : :: **. ** .* .
Mb2071c|M.bovis_AF2122/97 -----
Rv2045c|M.tuberculosis_H37Rv -----
MAV_2466|M.avium_104 -----
MMAR_3020|M.marinum_M -----
MUL_2261|M.ulcerans_Agy99 -----
MSMEG_3002|M.smegmatis_MC2_155 -----
TH_2744|M.thermoresistible__bu -----
Mflv_3787|M.gilvum_PYR-GCK KRSSV
Mvan_2609|M.vanbaalenii_PYR-1 -----
MAB_2866c|M.abscessus_ATCC_199 -----