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SLMSKVNSVRSVAVVATVAAAAALTLGACGSGSDEADSADKIVVYSGRSENLVAPLIEKFTSDTGIEVET RYAGSGELAAQLITEGDKSPADVFLSQDAGALGAVSEAGLFAPINDEAMAAVPANFSAADKSWLGVSGRA RVLVYNPDIAPNPPDTIDGLLAPEWKGKIGFAPSNASWQSFVTGLRVIRGDDGARQWLEAFKAQDPQPYE NNVAVRDAVDAGQIPLGVVNHYYLYELVDAKGEQAVKARNKFMAPGDPGGLINVAGVGVLKSAANPEGAQ AFASYLIGKSAQEYFAGETKEYPLIEGVEPSGEMPQLSELQPPAVDLSQLSDLEATQELLVETGLLTN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3636 | - | - | 100% (349) | ferric iron-binding periplasmic protein of ABC transporter |
| M. smegmatis MC2 155 | MSMEG_6668 | - | 8e-09 | 23.24% (241) | ABC transporter, periplasmic substrate-binding protein, |
| M. smegmatis MC2 155 | MSMEG_6524 | - | 3e-06 | 27.32% (194) | polyamine/opine/phosphonate ABC transporter periplasmic |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1888 | modA | 1e-06 | 36.89% (103) | molybdate-binding lipoprotein |
| M. gilvum PYR-GCK | Mflv_3363 | - | 1e-153 | 80.00% (330) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv1857 | modA | 1e-06 | 36.89% (103) | molybdate-binding lipoprotein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1501 | - | 1e-05 | 22.44% (312) | ABC transporter periplasmic protein |
| M. marinum M | MMAR_2731 | modA | 4e-10 | 36.07% (122) | molybdate-binding lipoprotein ModA |
| M. avium 104 | MAV_2863 | modA | 1e-07 | 27.02% (285) | molybdate ABC transporter, periplasmic molybdate-binding |
| M. thermoresistible (build 8) | TH_0285 | - | 1e-150 | 77.46% (346) | ferric iron-binding periplasmic protein of ABC transporter |
| M. ulcerans Agy99 | MUL_3022 | modA | 2e-08 | 38.24% (102) | molybdate-binding lipoprotein ModA |
| M. vanbaalenii PYR-1 | Mvan_3093 | - | 1e-152 | 77.26% (343) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1888|M.bovis_AF2122/97 ------------------------MRWIGLSTGLVSAMLVAGLVACGSNS
Rv1857|M.tuberculosis_H37Rv ------------------------MRWIGLSTGLVSAMLVAGLVACGSNS
MMAR_2731|M.marinum_M ------------------------MTRVGMLAGMVSALLVW-VVGCGS--
MUL_3022|M.ulcerans_Agy99 ------------------------------------------MVGCGS--
MAV_2863|M.avium_104 ------------------------MRRIGILTGLLSVVLIAGMTGCGS--
Mflv_3363|M.gilvum_PYR-GCK -------------------MSKS-FTRLAGVFGAVAAVLAFS--ACGSQP
Mvan_3093|M.vanbaalenii_PYR-1 -------------------MSN---SRFAGVLAVITAMLALT--ACGSGS
MSMEG_3636|M.smegmatis_MC2_155 ----------------MSLMSKVNSVRSVAVVATVAAAAALTLGACGSGS
TH_0285|M.thermoresistible__bu VRTIFNRAGFNRRGFNRRGFNRRGFNRIAVLLTAAATALALG--ACGSAP
MAB_1501|M.abscessus_ATCC_1997 ---------------------MKSPWWMQILKWASIAVLVAAVSACGGTG
.**.
Mb1888|M.bovis_AF2122/97 PASS--PAGPTQGARSIVVFAAASLQSAFTQIGEQFKAGNPGVNVNFAFA
Rv1857|M.tuberculosis_H37Rv PASS--PAGPTQGARSIVVFAAASLQSAFTQIGEQFKAGNPGVNVNFAFA
MMAR_2731|M.marinum_M ------PSRPADGARSITIFAAASLKTAFTQIGERFKTANPGVGVELDFA
MUL_3022|M.ulcerans_Agy99 ------PSRPAEGARSITIFAAASLKTAFTQIGERFKTANPGVGVELDFA
MAV_2863|M.avium_104 ------KSQPPPTAGKLMVFAAASLRPAFTQIAERFKAQNPGTGIEFEFA
Mflv_3363|M.gilvum_PYR-GCK ---------AGEDADKIVVYSGRSEE-LVKPLIEQFTT-DTGIQVETRYA
Mvan_3093|M.vanbaalenii_PYR-1 ---------QSEDADKIVVYAGRSEA-LIAPLIEQFTA-DTGIEVEARYA
MSMEG_3636|M.smegmatis_MC2_155 D--------EADSADKIVVYSGRSEN-LVAPLIEKFTS-DTGIEVETRYA
TH_0285|M.thermoresistible__bu ESDTDGQTTAEAAGEKLVVYSGRNEQ-LVAPLIERFST-DTGIEVDVRYA
MAB_1501|M.abscessus_ATCC_1997 ---------GGNGPNSVTVYSADGLGRWYQARFHEFSQ-ITGISVNLVEA
.: :::. . ..*. .* :: *
Mb1888|M.bovis_AF2122/97 GSSELATQLTQG---ATADVFASADTAQMDSVAKAGLLA--------GHP
Rv1857|M.tuberculosis_H37Rv GSSELATQLTQG---ATADVFASADTAQMDSVAKAGLLA--------GHP
MMAR_2731|M.marinum_M GSSELATQLTQG---ATADVFASADTAQMDTVAKAGLLA--------ADP
MUL_3022|M.ulcerans_Agy99 GSSELATQLTQG---ATADVFASADTAQMDTVAKAGLLA--------ADP
MAV_2863|M.avium_104 GSSELATQLTQG---ATADVFASADTAQMDVVAKAGLLA--------ADP
Mflv_3363|M.gilvum_PYR-GCK GSGELAAQLLTEGDKSPADVFLSQDAGALGAVSKAGLFAPINADALAAVP
Mvan_3093|M.vanbaalenii_PYR-1 GSGELAAQLITEGDKSPADVFLSQDAGALGAVSKAGLFAPISPDTLAAVP
MSMEG_3636|M.smegmatis_MC2_155 GSGELAAQLITEGDKSPADVFLSQDAGALGAVSEAGLFAPINDEAMAAVP
TH_0285|M.thermoresistible__bu GSGELAAQLITEGDRSPADVFLSQDAGALGAVTEAGLFTPIDPETLAKVP
MAB_1501|M.abscessus_ATCC_1997 GSAEVVSRIAKEKANPQADLLVTLPPFVQKAAGSGLLVG--ADIDIAAVD
**.*:.::: . **:: : . . .. *.
Mb1888|M.bovis_AF2122/97 TNFATNTMVIVAAAG--------------NPKKIRSFADLTRPG-----L
Rv1857|M.tuberculosis_H37Rv TNFATNTMVIVAAAG--------------NPKKIRSFADLTRPG-----L
MMAR_2731|M.marinum_M TNFASNTLVIVTAPG--------------NPKHVGSFADLSRSD-----L
MUL_3022|M.ulcerans_Agy99 TNFASNTLVIVTAPG--------------NPKHVGSFADLSRSD-----L
MAV_2863|M.avium_104 TNFASNTLVIVTAPG--------------NPKRIGSFADLARPG-----L
Mflv_3363|M.gilvum_PYR-GCK KQYSAADGTWLGVSGRARVIVYNPTLVPDPPDTIDGLLAPEWKG-KIGFA
Mvan_3093|M.vanbaalenii_PYR-1 AQYSAADGTWVGVSGRARVIVYNPTLAPNPPDTIDGLLAPEWKG-KIGFA
MSMEG_3636|M.smegmatis_MC2_155 ANFSAADKSWLGVSGRARVLVYNPDIAPNPPDTIDGLLAPEWKG-KIGFA
TH_0285|M.thermoresistible__bu AHFSAADGTWLGVSGRARVVVYNPDLAPEPPDTIDGLLDPQWAGGKIGFA
MAB_1501|M.abscessus_ATCC_1997 QRNRDRNGRYVAIVDNYLTFIANPAAALKDPRWDDLLDPRFRGKLQYSTP
. : . * :
Mb1888|M.bovis_AF2122/97 NVVVCQPSVPCGSATRRIEDATGIHLNPVSEELSVTDVLNKVITGQADAG
Rv1857|M.tuberculosis_H37Rv NVVVCQPSVPCGSATRRIEDATGIHLNPVSEELSVTDVLNKVITGQADAG
MMAR_2731|M.marinum_M TVVVCQQQVPCGAATQRIEDGTGVHLNPVSEELSVTDVLNKVTTGQADAA
MUL_3022|M.ulcerans_Agy99 IVVVCQQQVPCGAATQRIEDGTGVHLNRVSEELSVTDVLNKVTTGQADAA
MAV_2863|M.avium_104 TVVTCQRPVPCGAAAHRVEDSTGVHLNPVSEEPSVTDALTKVTSGQADAA
Mflv_3363|M.gilvum_PYR-GCK PSNASWQAFVTGLRVIRGDDGAEQWLRAFKAQDPQAFENNVAIRDAVDAG
Mvan_3093|M.vanbaalenii_PYR-1 PSNASWQAFVTGLRVLRGDDGAERWLRAFKDQDPQAFENNVAVRDAVNSG
MSMEG_3636|M.smegmatis_MC2_155 PSNASWQSFVTGLRVIRGDDGARQWLEAFKAQDPQPYENNVAVRDAVDAG
TH_0285|M.thermoresistible__bu PSNASWQSFVTGLRVLRGEDGARQWLEAFKAQEPQAYENNVAVRDAVDAG
MAB_1501|M.abscessus_ATCC_1997 GQAGDGTAMLVLLQHLMGNQGAVDYLRRLQHNNVGPSSSTGKLQPKVSNG
. ::.: *. .. : . . .. .
Mb1888|M.bovis_AF2122/97 --------------LVYVSDALSVATKVTCVRFPEAAGVVNVYAIAVLKR
Rv1857|M.tuberculosis_H37Rv --------------LVYVSDALSVATKVTCVRFPEAAGVVNVYAIAVLKR
MMAR_2731|M.marinum_M --------------LVYLTDAMSAGSTVSTIKFPQAAPAVNVYPIAVLSN
MUL_3022|M.ulcerans_Agy99 --------------LVYLTDAMSAGSTVSTIKFPQAAPAVNVYPIAVLSN
MAV_2863|M.avium_104 --------------LVYVTDARTAGSKVATVNFPEAAGAVNVYPIGVLKQ
Mflv_3363|M.gilvum_PYR-GCK QIPLGIANHYYLYELINAKGADAVTARNQFMAPGDPGGLVNVAGVGVLKS
Mvan_3093|M.vanbaalenii_PYR-1 QIPLGLVNHYYLYELINSKGPDAVVAENKFMAPGDPGGLINVAGVGVLKA
MSMEG_3636|M.smegmatis_MC2_155 QIPLGVVNHYYLYELVDAKGEQAVKARNKFMAPGDPGGLINVAGVGVLKS
TH_0285|M.thermoresistible__bu QIPLGLVNHYYLYELIKAKGADAVVAENQYMAPGDPGGLINVAGVGVLKT
MAB_1501|M.abscessus_ATCC_1997 E--LWVANGDLQMNLASIREDRSNFSIFIPAARDGKRSTISLPYVAAVTN
* : : :.: :..:.
Mb1888|M.bovis_AF2122/97 -TSQPALARQFVAMVTAAAGRRILDQSGFAKP------------------
Rv1857|M.tuberculosis_H37Rv -TSQPALARQFVAMVTAAAGRRILDQSGFAKP------------------
MMAR_2731|M.marinum_M -APQPGLARKFVDMVTAETGRRILDQSGFAKP------------------
MUL_3022|M.ulcerans_Agy99 -APQPGLARKFVDMVTAETGRRILDQSGFAKP------------------
MAV_2863|M.avium_104 -APLATQARNFVDLVTSPPGQQILAQAGFAKP------------------
Mflv_3363|M.gilvum_PYR-GCK -APNPEGAQAFASYLIGETAQKYFAEETAEYPLVAGVATSSEM-PPLADL
Mvan_3093|M.vanbaalenii_PYR-1 -APNPEGAQEFAKYLVGESAQKYFAQETAEYPLLASVPPSAEM-PALADL
MSMEG_3636|M.smegmatis_MC2_155 -AANPEGAQAFASYLIGKSAQEYFAGETKEYPLIEGVEPSGEM-PQLSEL
TH_0285|M.thermoresistible__bu -ASNPEAAQRFAAYLVEKDAQEYFAEETSEYPLIDGVPAGPEM-PPLADL
MAB_1501|M.abscessus_ATCC_1997 GAPHVENARKLLAYLLSVPVQRTIPREALGMPVRADVQPEAGANTPAQVL
:. *: : : :. : *
Mb1888|M.bovis_AF2122/97 ------------------------------
Rv1857|M.tuberculosis_H37Rv ------------------------------
MMAR_2731|M.marinum_M ------------------------------
MUL_3022|M.ulcerans_Agy99 ------------------------------
MAV_2863|M.avium_104 ------------------------------
Mflv_3363|M.gilvum_PYR-GCK RPPAVDLSQLDDIETTQEMLVETGLLTN--
Mvan_3093|M.vanbaalenii_PYR-1 APPAVDLSQLDDIEATQELLVKTGLLTN--
MSMEG_3636|M.smegmatis_MC2_155 QPPAVDLSQLSDLEATQELLVETGLLTN--
TH_0285|M.thermoresistible__bu QPPEVDLSQLSDLEATQELLVETGLLTN--
MAB_1501|M.abscessus_ATCC_1997 EGVRIWHPDWDQVVSTLDASLIAYHQETGS