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M. tuberculosis H37Rv Rv1857 (modA)

annotation: PROBABLE MOLYBDATE-BINDING LIPOPROTEIN MODA
coordinates: 2104985 - 2105770
length: 261

VRWIGLSTGLVSAMLVAGLVACGSNSPASSPAGPTQGARSIVVFAAASLQSAFTQIGEQFKAGNPGVNVN
FAFAGSSELATQLTQGATADVFASADTAQMDSVAKAGLLAGHPTNFATNTMVIVAAAGNPKKIRSFADLT
RPGLNVVVCQPSVPCGSATRRIEDATGIHLNPVSEELSVTDVLNKVITGQADAGLVYVSDALSVATKVTC
VRFPEAAGVVNVYAIAVLKRTSQPALARQFVAMVTAAAGRRILDQSGFAKP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1857modA-100% (261)PROBABLE MOLYBDATE-BINDING LIPOPROTEIN MODA
M. tuberculosis H37RvRv2400csubI5e-0929.34% (167) sulfate-binding lipoprotein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1888modA1e-143100.00% (261) molybdate-binding lipoprotein
M. gilvum PYR-GCKMflv_3859-9e-7251.72% (261) molybdenum ABC transporter, periplasmic molybdate-binding
M. leprae Br4923MLBr_00615subI6e-0620.14% (288) putative sulphate-binding protein
M. abscessus ATCC 19977MAB_2433-3e-6752.33% (258) molybdenum ABC transporter periplasmic protein
M. marinum MMMAR_2731modA1e-9670.16% (258) molybdate-binding lipoprotein ModA
M. avium 104MAV_2863modA4e-9065.13% (261) molybdate ABC transporter, periplasmic molybdate-binding
M. smegmatis MC2 155MSMEG_2016modA1e-6857.47% (221) molybdate ABC transporter, periplasmic molybdate-binding
M. thermoresistible (build 8)TH_1176-5e-6549.62% (260) PROBABLE MOLYBDATE-BINDING LIPOPROTEIN MODA
M. ulcerans Agy99MUL_3022modA9e-9371.19% (243) molybdate-binding lipoprotein ModA
M. vanbaalenii PYR-1Mvan_2538-6e-6950.97% (257) molybdenum ABC transporter, periplasmic molybdate-binding

CLUSTAL 2.0.9 multiple sequence alignment


Rv1857|M.tuberculosis_H37Rv         -MRWIG-----------LSTGLVSAMLVAGLVA-CGSNSPASSPAGPTQG
Mb1888|M.bovis_AF2122/97            -MRWIG-----------LSTGLVSAMLVAGLVA-CGSNSPASSPAGPTQG
MMAR_2731|M.marinum_M               -MTRVG-----------MLAGMVSALLVW-VVG-CGS------PSRPADG
MUL_3022|M.ulcerans_Agy99           ------------------------------MVG-CGS------PSRPAEG
MAV_2863|M.avium_104                -MRRIG-----------ILTGLLSVVLIAGMTG-CGS------KSQPPPT
Mflv_3859|M.gilvum_PYR-GCK          MIRHPA-----------VAVALTVATLMSGCST-AGEDRPAATPPTSDAV
Mvan_2538|M.vanbaalenii_PYR-1       MRSMPG-----------LTSALIAVVLVAGCSS-SRTD-SGPTP------
MSMEG_2016|M.smegmatis_MC2_155      ---MIR-----------VVSVVVGVFLLAGCTP-APAN------------
MAB_2433|M.abscessus_ATCC_1997      MTGSTRNVLTSRAWKVLAATLLAGSLIVSGCGTRTGSGGGSASPSTGAGD
TH_1176|M.thermoresistible__bu      MIRVRR------------WLSVCLALMLPAVAG-CGTG--------RTGG
MLBr_00615|M.leprae_Br4923          MFKDIG----RFMRWRHSMVVGVTLASTTDVVAACHGGASDVVGGGTAHA
                                                                                      

Rv1857|M.tuberculosis_H37Rv         ARSIVVFAAASLQSAFTQIGEQFKAGNPG--VNVNFAFAGSSELATQLTQ
Mb1888|M.bovis_AF2122/97            ARSIVVFAAASLQSAFTQIGEQFKAGNPG--VNVNFAFAGSSELATQLTQ
MMAR_2731|M.marinum_M               ARSITIFAAASLKTAFTQIGERFKTANPG--VGVELDFAGSSELATQLTQ
MUL_3022|M.ulcerans_Agy99           ARSITIFAAASLKTAFTQIGERFKTANPG--VGVELDFAGSSELATQLTQ
MAV_2863|M.avium_104                AGKLMVFAAASLRPAFTQIAERFKAQNPG--TGIEFEFAGSSELATQLTQ
Mflv_3859|M.gilvum_PYR-GCK          TGDLTVFAAASLKSTFTELGSRFETDHPG--TQVVFNFAGSTDLAAQISQ
Mvan_2538|M.vanbaalenii_PYR-1       NGTVTVFAASSLKNTFTELGAQFEKDHPG--TEVTFNFAGSADLVAQLSQ
MSMEG_2016|M.smegmatis_MC2_155      DDHLTVFAAASLKSVFTELGKRFEDANPG--ATVEFNFAGSSDLATQLTQ
MAB_2433|M.abscessus_ATCC_1997      PVRLHVLAAASLRKAFTEIGRSFESTHAG--TTVEFTFAGSSDLVTQLTQ
TH_1176|M.thermoresistible__bu      STAVTVYAAASLQQAFTTLGELFEAEHPD--VTVRFTFAGSADLATQLLG
MLBr_00615|M.leprae_Br4923          HTSIALVAYSAPGPGWGKVIPAFNDARSGDGVQVVTSYGASGDQSRGVVD
                                       : : * ::    :  :   *:  ...  . :   :..* :    :  

Rv1857|M.tuberculosis_H37Rv         GATADVFASADTAQMDSVAKAGLLAGHPTNFATN------TMVIVAAAGN
Mb1888|M.bovis_AF2122/97            GATADVFASADTAQMDSVAKAGLLAGHPTNFATN------TMVIVAAAGN
MMAR_2731|M.marinum_M               GATADVFASADTAQMDTVAKAGLLAADPTNFASN------TLVIVTAPGN
MUL_3022|M.ulcerans_Agy99           GATADVFASADTAQMDTVAKAGLLAADPTNFASN------TLVIVTAPGN
MAV_2863|M.avium_104                GATADVFASADTAQMDVVAKAGLLAADPTNFASN------TLVIVTAPGN
Mflv_3859|M.gilvum_PYR-GCK          GAPADVFASADTSTMDRAVDGGTVAGDPVVFATN------TLTIVTALGN
Mvan_2538|M.vanbaalenii_PYR-1       GAPADVFASADTRNMTRAVDGGLVAGQPADFASN------TLTIVTPPGN
MSMEG_2016|M.smegmatis_MC2_155      GAPADVFASADAPNMNKVVDAGLVHGDPVDFAAN------TLTIVTAPGN
MAB_2433|M.abscessus_ATCC_1997      GAQADVLATADSANMDKAWKAHAVVN-PVDFAAN------TLTIVVAPGN
TH_1176|M.thermoresistible__bu      GADADVFAAADEATMERVAAAGLLSGPPVIFAAN------TLTVVTAPGN
MLBr_00615|M.leprae_Br4923          GKPADIVNFSVETDITRLVKVGKVSKDWDTDATKGIPFGSVVTLVVRTGN
                                    *  **:.  :    :        :       *::      .:.:*.  **

Rv1857|M.tuberculosis_H37Rv         PKKIRSFADLTRPGLNVVVCQPSVP-----------------CGSATRRI
Mb1888|M.bovis_AF2122/97            PKKIRSFADLTRPGLNVVVCQPSVP-----------------CGSATRRI
MMAR_2731|M.marinum_M               PKHVGSFADLSRSDLTVVVCQQQVP-----------------CGAATQRI
MUL_3022|M.ulcerans_Agy99           PKHVGSFADLSRSDLIVVVCQQQVP-----------------CGAATQRI
MAV_2863|M.avium_104                PKRIGSFADLARPGLTVVTCQRPVP-----------------CGAAAHRV
Mflv_3859|M.gilvum_PYR-GCK          PRAIASFADLAGPGVQLVVCAPQVP-----------------CGSATEKV
Mvan_2538|M.vanbaalenii_PYR-1       PRGITSFGDLTRPGTQVVVCAPQVP-----------------CGSAAERV
MSMEG_2016|M.smegmatis_MC2_155      PKHITSFADLTKPGISVVVCAPQVP-----------------CGAATEKV
MAB_2433|M.abscessus_ATCC_1997      PKGIGAFGDLTRPGLDVVVCAPQVP-----------------CGAATAGV
TH_1176|M.thermoresistible__bu      PHGLTGFADLARAGPAVVTCAPQVP-----------------CGAATQRL
MLBr_00615|M.leprae_Br4923          PKNIKDWDDLVRPGVEVIMPNPLSSGSAKWNLLAPYAAKSEGCRNSQAGI
                                    *: :  : **  ..  ::      .                 *  :   :

Rv1857|M.tuberculosis_H37Rv         EDATGIHLNPVSEEL-SVTDVLNKVITGQADAGLVYVSDALSVATKVTCV
Mb1888|M.bovis_AF2122/97            EDATGIHLNPVSEEL-SVTDVLNKVITGQADAGLVYVSDALSVATKVTCV
MMAR_2731|M.marinum_M               EDGTGVHLNPVSEEL-SVTDVLNKVTTGQADAALVYLTDAMSAGSTVSTI
MUL_3022|M.ulcerans_Agy99           EDGTGVHLNRVSEEL-SVTDVLNKVTTGQADAALVYLTDAMSAGSTVSTI
MAV_2863|M.avium_104                EDSTGVHLNPVSEEP-SVTDALTKVTSGQADAALVYVTDARTAGSKVATV
Mflv_3859|M.gilvum_PYR-GCK          EAATGVTLTPVSEES-AVTDVLGKVTSGQADAGLVYVTDAAAAGDAVTAV
Mvan_2538|M.vanbaalenii_PYR-1       EEAAGATLTPVSEES-AVADVLGKVTSGQADAGLVYVTDAVAAGDRVTEI
MSMEG_2016|M.smegmatis_MC2_155      EKATGVTLHPVSEES-AVTDVLGKVTSGQADAGLVYVTDAKGAGAAVAAV
MAB_2433|M.abscessus_ATCC_1997      SKETGVHLNPASEES-SVTDVLNKVIAGQADAGLVYVTDAKAAADKVATV
TH_1176|M.thermoresistible__bu      EQLTGVDLAPVSEEN-SVSDVLHKVTVGQADAGVVYRTDARRAGDTVHTV
MLBr_00615|M.leprae_Br4923          DFVNRLVAEHVKLRLGSAREATDAFVQGSGDVLISYENEAIAAERQGKPV
                                    .         .. .  :. :.   .  *..*. : * .:*  .      :

Rv1857|M.tuberculosis_H37Rv         RFPEAAGVVNVY-AIAVLKRTSQPALARQFVAMVTAAAGRRILDQSGFAK
Mb1888|M.bovis_AF2122/97            RFPEAAGVVNVY-AIAVLKRTSQPALARQFVAMVTAAAGRRILDQSGFAK
MMAR_2731|M.marinum_M               KFPQAAPAVNVY-PIAVLSNAPQPGLARKFVDMVTAETGRRILDQSGFAK
MUL_3022|M.ulcerans_Agy99           KFPQAAPAVNVY-PIAVLSNAPQPGLARKFVDMVTAETGRRILDQSGFAK
MAV_2863|M.avium_104                NFPEAAGAVNVY-PIGVLKQAPLATQARNFVDLVTSPPGQQILAQAGFAK
Mflv_3859|M.gilvum_PYR-GCK          AFPEAADAVNSY-PIAALADSTNPAAASEFIEFVTGPQGRDVLAAAGFGR
Mvan_2538|M.vanbaalenii_PYR-1       AFPESGVAANTY-PIAALAGSRNPDAAQQFMALVTGPQGREVLSAAGFGP
MSMEG_2016|M.smegmatis_MC2_155      AFGESADAVNTY-PIATLKDSGDIETAQRFVDLVVSPEGQEVLSEAGFVA
MAB_2433|M.abscessus_ATCC_1997      EIPEARSIVNTY-PIAATANSRHPERAAQFIETVTGDIGHKVLAAAGFSA
TH_1176|M.thermoresistible__bu      EVPAAAAVPNRY-PVAVPADAARPDLGQRFIDLITGAAGRDVLAQNGFSE
MLBr_00615|M.leprae_Br4923          EHINPPVTFKIENPLAVVSTSAHLEVATAFKNFQYTTAAQGLWAQAGFRP
                                        .    :   .:..   :     .  *        .: :    **  

Rv1857|M.tuberculosis_H37Rv         P-------------------------------------------------
Mb1888|M.bovis_AF2122/97            P-------------------------------------------------
MMAR_2731|M.marinum_M               P-------------------------------------------------
MUL_3022|M.ulcerans_Agy99           P-------------------------------------------------
MAV_2863|M.avium_104                P-------------------------------------------------
Mflv_3859|M.gilvum_PYR-GCK          P-------------------------------------------------
Mvan_2538|M.vanbaalenii_PYR-1       P-------------------------------------------------
MSMEG_2016|M.smegmatis_MC2_155      P-------------------------------------------------
MAB_2433|M.abscessus_ATCC_1997      P-------------------------------------------------
TH_1176|M.thermoresistible__bu      PR------------------------------------------------
MLBr_00615|M.leprae_Br4923          VDPAVSADFSDQFPAPVKLWTIADLGGWSTVDPQLFDKNTGSITKVYMQA
                                                                                      

Rv1857|M.tuberculosis_H37Rv         --
Mb1888|M.bovis_AF2122/97            --
MMAR_2731|M.marinum_M               --
MUL_3022|M.ulcerans_Agy99           --
MAV_2863|M.avium_104                --
Mflv_3859|M.gilvum_PYR-GCK          --
Mvan_2538|M.vanbaalenii_PYR-1       --
MSMEG_2016|M.smegmatis_MC2_155      --
MAB_2433|M.abscessus_ATCC_1997      --
TH_1176|M.thermoresistible__bu      --
MLBr_00615|M.leprae_Br4923          TG