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MGRHHAPEDRRAATTRPVTRTQIRHIAIVMTALAMGVLAMIASYSGAFAKPTLHHMTVAVAAPTQLVDQL REQDSLSVTDVPDEAAAHAQVLQRDADAALVVAAPDRLDIYVAGGGGRSVATAAESVGRAAAEQAGLVPA VTDIAPTSPGNPSGTVEFYAIIFISLGASVGAAAFGYLAGPVRRPMTLALRTVTLAAYSALLAGLVTVYV DPVLDALVGHPWQVFGVLWLYCLAVGGAVTGVSAAFGPVASLMLTAFLVIVGNAAAAGPVGRPLLSSFYS TFNLIVPQGSGVSLLRSVEYFDGNGAAQPLLTLAVWAAAGCVLAVLGTAVRSARVRNSALRVARRCAPGR GPIYRGRHDRNRSERALLPAGVLSPAD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3573 | - | - | 100% (377) | integral membrane protein, putative |
| M. smegmatis MC2 155 | MSMEG_0720 | - | 3e-24 | 27.43% (339) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0186c | - | 2e-05 | 22.92% (336) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_3330 | - | 1e-117 | 59.79% (378) | integral membrane protein |
| M. tuberculosis H37Rv | Rv0180c | - | 2e-05 | 22.92% (336) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5199 | - | 9e-06 | 26.87% (227) | hypothetical protein MMAR_5199 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2357 | - | 2e-22 | 26.30% (346) | integral membrane protein |
| M. ulcerans Agy99 | MUL_4272 | - | 6e-06 | 26.87% (227) | hypothetical protein MUL_4272 |
| M. vanbaalenii PYR-1 | Mvan_3056 | - | 1e-122 | 68.28% (331) | integral membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0186c|M.bovis_AF2122/97 MSQAQPRPAAPNPKRNVKAIRTVRFWMAPIATTLALMSALAALYLG-GIL
Rv0180c|M.tuberculosis_H37Rv MSQAQPRPAAPNPKRNVKAIRTVRFWMAPIATTLALMSALAALYLG-GIL
Mflv_3330|M.gilvum_PYR-GCK MGRHHTPD---IPPIR--DRTAVRTTLLALAGLTVFVIAMVASYSG-AFA
Mvan_3056|M.vanbaalenii_PYR-1 MGKHHTPE---ASTFR--DRSAVRTTVLALAALTVFVIAMVASYSG-AFA
MSMEG_3573|M.smegmatis_MC2_155 MGRHHAPEDRRAATTRPVTRTQIRHIAIVMTALAMGVLAMIASYSG-AFA
MMAR_5199|M.marinum_M MSTLPPPGYPVEPNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYG
MUL_4272|M.ulcerans_Agy99 MSTLPPPGYPVEPNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYG
TH_2357|M.thermoresistible__bu MTTQSAPPNDRSTIRRHEQPAAVRATGIVVVLTVAIAIIAIAFAWPASRS
* . . . * .
Mb0186c|M.bovis_AF2122/97 NPMTNLRHFPIALVNEDAGPAGQQIVDGLVSGL--DKNKFDIRVVSPDEA
Rv0180c|M.tuberculosis_H37Rv NPMTNLRHFPIALVNEDAGPAGQQIVDGLVSGL--DKNKFDIRVVSPDEA
Mflv_3330|M.gilvum_PYR-GCK NPT--LHHMTVAVS------APQQVVDGLR-----AEHALTVHEFGDAAS
Mvan_3056|M.vanbaalenii_PYR-1 KPT--LHHMTVAVA------APPEIIDGLR-----DQHTLSVDEVGDAAA
MSMEG_3573|M.smegmatis_MC2_155 KPT--LHHMTVAVA------APTQLVDQLR-----EQDSLSVTDVPDEAA
MMAR_5199|M.marinum_M APPPGYGPPPPGYGPPP-GYGPPPPGYGPPPGYGPPPPGYGPPLVPGAVK
MUL_4272|M.ulcerans_Agy99 APPPGYGPPP-GYAPPPPGYGPPP-GYGPPPGYGPPPPGYGPPLVPGAVK
TH_2357|M.thermoresistible__bu APG----DLPIGVAAP-----PPVTAQITARLAEQAPDAFDVRAFDDDAA
* . . .
Mb0186c|M.bovis_AF2122/97 RRLLDTAAVYGSALIPPTFSSQLRDFGASAVTPTRTDRPAITISTNPRAG
Rv0180c|M.tuberculosis_H37Rv RRLLDTAAVYGSALIPPTFSSQLRDFGASAVTPTRTDRPAITISTNPRAG
Mflv_3330|M.gilvum_PYR-GCK ---------------------------ARAQVLERTADTAFAVNPDGHLT
Mvan_3056|M.vanbaalenii_PYR-1 ---------------------------ARAQVYQRSADAALAVTPDQRMT
MSMEG_3573|M.smegmatis_MC2_155 ---------------------------AHAQVLQRDADAALVVAAPDRLD
MMAR_5199|M.marinum_M PGIIPLRP-------------------LTLSDIFNGAVGYIRANPKATLG
MUL_4272|M.ulcerans_Agy99 PGIIPLRP-------------------LTLSDIFNGAVGYIRANPKATLG
TH_2357|M.thermoresistible__bu ---------------------------LRAAIRDREVYGGLSIGAGPPTL
. : .
Mb0186c|M.bovis_AF2122/97 TLAASIAGQTLTRALTVVNGKVGERLTAEVAAQTGGVALAGAAAAGLASP
Rv0180c|M.tuberculosis_H37Rv TLAASIAGQTLTRALTVVNGKVGERLTAEVAAQTGGVALAGAAAAGLASP
Mflv_3330|M.gilvum_PYR-GCK VYVAGGGGHSVAAAAELVG-----REAAERAGLTPVVEDVAPTSA-----
Mvan_3056|M.vanbaalenii_PYR-1 IYVAGGGGRSVAAAAELVG-----RETAERADLSPVVEDVAPTSP-----
MSMEG_3573|M.smegmatis_MC2_155 IYVAGGGGRSVATAAESVG-----RAAAEQAGLVPAVTDIAPTSP-----
MMAR_5199|M.marinum_M LTAIVVVVMQVITLLATIG----PLEAASRFDTHPSELSWGVVGAWT---
MUL_4272|M.ulcerans_Agy99 LTAIVVVVMQVITLLAAIG----PLEAASRFDTHPSELSWGVVGAWT---
TH_2357|M.thermoresistible__bu LIATGGSPAVAQLLTQMAG------GIAEQSGMPLRTEDLAAPPP-----
. . *. . .
Mb0186c|M.bovis_AF2122/97 IDVKSTAYNPLPNGTGNGLSAFYYALLLLLAGFTGSIVVSTLVDSMLGYV
Rv0180c|M.tuberculosis_H37Rv IDVKSTAYNPLPNGTGNGLSAFYYALLLLLAGFTGSIVVSTLVDSMLGYV
Mflv_3330|M.gilvum_PYR-GCK -------------GDPSGTVEFYAVIFLSIGASLG----AALLGRLMGPV
Mvan_3056|M.vanbaalenii_PYR-1 -------------GDPSGTVEFYAVIFLSIGASLG----AALLGRLMGSV
MSMEG_3573|M.smegmatis_MC2_155 -------------GNPSGTVEFYAIIFISLGASVG----AAAFGYLAGPV
MMAR_5199|M.marinum_M -------------GSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSPITIS
MUL_4272|M.ulcerans_Agy99 -------------GSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSPITIS
TH_2357|M.thermoresistible__bu -------------DDPRGVGLAASALPITLAGLLP---------AIALVL
. . : :..
Mb0186c|M.bovis_AF2122/97 PAEFGPVYRFAEQVNISRFRTLLVKWAVMVVLALLTSGVYLAIAHGLGMP
Rv0180c|M.tuberculosis_H37Rv PAEFGPVYRFAEQVNISRFRTLLVKWAVMVVLALLTSGVYLAIAHGLGMP
Mflv_3330|M.gilvum_PYR-GCK RTPATLALRTASLSVFSAVLAGVVTLYTGPVLDALTGHSWQVFG------
Mvan_3056|M.vanbaalenii_PYR-1 RTPATLALRTVSLAAFSAVLAGAVTAYVGPVLDALTGHIWQVFG------
MSMEG_3573|M.smegmatis_MC2_155 RRPMTLALRTVTLAAYSALLAGLVTVYVDPVLDALVGHPWQVFG------
MMAR_5199|M.marinum_M EAWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANG------
MUL_4272|M.ulcerans_Agy99 EAWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANG------
TH_2357|M.thermoresistible__bu ALRREVWTRFAATVVFAALAAWTIALLLRFVFGSITDNFWGVTAG-----
* : . : *. :.. . .
Mb0186c|M.bovis_AF2122/97 IPLGWQVWLYGVFAIIAVGVTSSSLIAVLGSMGLLVSMLIFVILGLPSAG
Rv0180c|M.tuberculosis_H37Rv IPLGWQVWLYGVFAIIAVGVTSSSLIAVLGSMGLLVSMLIFVILGLPSAG
Mflv_3330|M.gilvum_PYR-GCK -----ALWLY----SMAVGGAVTGVAAAFGSAASVVLGLFLVVVGNAAAA
Mvan_3056|M.vanbaalenii_PYR-1 -----ALWLY----SMAVAGAVTGVAAAFGTAASVALGLFLVVVGNAAAA
MSMEG_3573|M.smegmatis_MC2_155 -----VLWLY----CLAVGGAVTGVSAAFGPVASLMLTAFLVIVGNAAAA
MMAR_5199|M.marinum_M --ATAALLGFPLVLLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFA
MUL_4272|M.ulcerans_Agy99 --ATAALLGFPLVLLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFA
TH_2357|M.thermoresistible__bu ------LTLG----ILAAGLTVLGLGSVFGRAGLAIGALLAILLGNPLSG
: :. : :. : .
Mb0186c|M.bovis_AF2122/97 ATVPLEAVPAFFRWLAQFEP-----MHQVFLGVRSLLYLNGNADAGLSQA
Rv0180c|M.tuberculosis_H37Rv ATVPLEAVPAFFRWLAQFEP-----MHQVFLGVRSLLYLNGNADAGLSQA
Mflv_3330|M.gilvum_PYR-GCK GPVGRPLLSGFYSTFTAIVP-----QGSGVSLLRSISYFGG---HGAAMS
Mvan_3056|M.vanbaalenii_PYR-1 GPVGRPLLSGFYSTFTTIVP-----QGSGVSLLRSISYFGG---HGATTP
MSMEG_3573|M.smegmatis_MC2_155 GPVGRPLLSSFYSTFNLIVP-----QGSGVSLLRSVEYFDG---NGAAQP
MMAR_5199|M.marinum_M LVTGGFWRVLGIRLLTAIVVGLVGGAISAPFGIVGQILLGATASEGSTGM
MUL_4272|M.ulcerans_Agy99 LVTGGFWRVLGIRLLTAIVVGLVGGAISAPFGIVGQILLGATASEGSTGM
TH_2357|M.thermoresistible__bu LNAAPELLPRGWGQLGQLLP-----QGANATLLRSTAYFDG---AGATTA
. : : : . :.. * :
Mb0186c|M.bovis_AF2122/97 LTMTSIGLIIGLLLGGFITHLYDRSSFHRIPG---------AVEMAIAVE
Rv0180c|M.tuberculosis_H37Rv LTMTSIGLIIGLLLGGFITHLYDRSSFHRIPG---------AVEMAIAVE
Mflv_3330|M.gilvum_PYR-GCK WVTLVVWAVTGAVLATLATAVR---VNYRAL-------------YERRVE
Mvan_3056|M.vanbaalenii_PYR-1 LVTLGIWAAAGCFLAVGATAAR---VNYRAL-------------YER---
MSMEG_3573|M.smegmatis_MC2_155 LLTLAVWAAAGCVLAVLGTAVRSARVRNSALRVARRCAPGRGPIYRGRHD
MMAR_5199|M.marinum_M FLVGMTLSSIGSAISQIITAPFTAGVVVLLYTDRR--MRAEAFDLVLQTG
MUL_4272|M.ulcerans_Agy99 FLVGMTLSSIGSAISQIITAPFTAGVVVLLYTDRR--MRAEAFDLVLQTG
TH_2357|M.thermoresistible__bu IWVLVCWVLVGTALIAVAALRQ----------------------------
* : :
Mb0186c|M.bovis_AF2122/97 HQAQYQARQSARESSSEQP-
Rv0180c|M.tuberculosis_H37Rv HQAQYQARQSARESSSEQP-
Mflv_3330|M.gilvum_PYR-GCK RAGGSRTLLRPGLLSSTD--
Mvan_3056|M.vanbaalenii_PYR-1 RVGQYRAVLRSRLVPSAD--
MSMEG_3573|M.smegmatis_MC2_155 RNRSERALLPAGVLSPAD--
MMAR_5199|M.marinum_M AAGGPAAVESTDNLWLTRPL
MUL_4272|M.ulcerans_Agy99 AAGGPAAVESTDTLWLTRPL
TH_2357|M.thermoresistible__bu ---RRTAEPHPAEMH-----
: .