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SQAQPRPAAPNPKRNVKAIRTVRFWMAPIATTLALMSALAALYLGGILNPMTNLRHFPIALVNEDAGPAG QQIVDGLVSGLDKNKFDIRVVSPDEARRLLDTAAVYGSALIPPTFSSQLRDFGASAVTPTRTDRPAITIS TNPRAGTLAASIAGQTLTRALTVVNGKVGERLTAEVAAQTGGVALAGAAAAGLASPIDVKSTAYNPLPNG TGNGLSAFYYALLLLLAGFTGSIVVSTLVDSMLGYVPAEFGPVYRFAEQVNISRFRTLLVKWAVMVVLAL LTSGVYLAIAHGLGMPIPLGWQVWLYGVFAIIAVGVTSSSLIAVLGSMGLLVSMLIFVILGLPSAGATVP LEAVPAFFRWLAQFEPMHQVFLGVRSLLYLNGNADAGLSQALTMTSIGLIIGLLLGGFITHLYDRSSFHR IPGAVEMAIAVEHQAQYQARQSARESSSEQP*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0180c | - | - | 100% (452) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0186c | - | 0.0 | 100.00% (452) | transmembrane protein |
M. gilvum PYR-GCK | Mflv_1752 | - | 5e-09 | 29.11% (158) | ABC-2 type transporter |
M. leprae Br4923 | MLBr_02600 | - | 0.0 | 76.73% (447) | hypothetical protein MLBr_02600 |
M. abscessus ATCC 19977 | MAB_4762 | - | 2e-07 | 25.79% (190) | hypothetical protein MAB_4762 |
M. marinum M | MMAR_0423 | - | 0.0 | 81.80% (456) | transmembrane protein |
M. avium 104 | MAV_5003 | - | 0.0 | 73.67% (452) | ABC-2 type transporter family protein |
M. smegmatis MC2 155 | MSMEG_5644 | - | 3e-09 | 29.61% (179) | membrane protein |
M. thermoresistible (build 8) | TH_0090 | - | 1e-08 | 25.82% (337) | membrane protein |
M. ulcerans Agy99 | MUL_1073 | - | 0.0 | 80.04% (456) | transmembrane protein |
M. vanbaalenii PYR-1 | Mvan_4995 | - | 3e-10 | 27.98% (243) | ABC-2 type transporter |
CLUSTAL 2.0.9 multiple sequence alignment Rv0180c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0186c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0423|M.marinum_M -------------------------------------------------- MUL_1073|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02600|M.leprae_Br4923 -------------------------------------------------- MAV_5003|M.avium_104 -------------------------------------------------- Mflv_1752|M.gilvum_PYR-GCK MALAGMSLGTDLSRYFHGRLPRIALATIIVMPLLYGAMYLWAFWNPFAEV Mvan_4995|M.vanbaalenii_PYR-1 MALAGMSLGTDLKRYSRGLMPRIALITIILMPLLYGAMYLWAFWNPFAEV MSMEG_5644|M.smegmatis_MC2_155 -MLAGMSLGTDFKRFSRGAMPRIALVIVIFMPLLYGAMYLWAFWNPFNEV TH_0090|M.thermoresistible__bu -------------------------------------------------- MAB_4762|M.abscessus_ATCC_1997 -MLAGLAFGSEIKRFGRSRMTRAAIVVLMLLPLVYGALYLWAYWDPFGHV Rv0180c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0186c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_0423|M.marinum_M -------------------------------------------------- MUL_1073|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02600|M.leprae_Br4923 -------------------------------------------------- MAV_5003|M.avium_104 -------------------------------------------------- Mflv_1752|M.gilvum_PYR-GCK NKVPVALVNEDRGASAQGQDLRAGDEVARALIDSGQLHLTEMSAQEAAEG Mvan_4995|M.vanbaalenii_PYR-1 NKVPVALVNEDRGASAQGQPLRAGDDVATALMQSGQLDLTEVSAQQAADG MSMEG_5644|M.smegmatis_MC2_155 DKVPVALVNEDKGAVAQGERLNAGQEVSDALVDSGELQLHRVSADEAADG TH_0090|M.thermoresistible__bu -------------------------------------------------- MAB_4762|M.abscessus_ATCC_1997 NKMPVALVNADKGATVSGQHVNIGEEISKSLTADGSMDWHVLSLDEARSG Rv0180c|M.tuberculosis_H37Rv ---------------MSQAQPRPAAPNPKRN------------------V Mb0186c|M.bovis_AF2122/97 ---------------MSQAQPRPAAPNPKRN------------------V MMAR_0423|M.marinum_M ---------------MSQSQPRHAAPNPKRS------------------I MUL_1073|M.ulcerans_Agy99 ---------------MSQSQPRHAAPNPKRS------------------I MLBr_02600|M.leprae_Br4923 ---------------MSQPQPRHAPFAPTRD------------------A MAV_5003|M.avium_104 ---------------MARSHPQHAAPNPNRN------------------I Mflv_1752|M.gilvum_PYR-GCK VAAGDYYFSITLPEDFSASVASPSGGDPRQATIRFTFNDANNYLASVIGQ Mvan_4995|M.vanbaalenii_PYR-1 VARGDYYFSITLPPDFSERVASPSGDDPQQAQIRFTFNDANNYLATIIGQ MSMEG_5644|M.smegmatis_MC2_155 VSSGRYYFSITLPEDFSEAIASPSGDSPQQATLRFTFNDANNYLGSIIGQ TH_0090|M.thermoresistible__bu -------------------------------------------------- MAB_4762|M.abscessus_ATCC_1997 VDHGNYYFMLELPPDFSEAIASPLTGEPKQANLVAVYNDANNYISSSIGR Rv0180c|M.tuberculosis_H37Rv KAIRTVRFWMAPIATTLALMSALAALYLG--GILNPMTNLRHFPIALVNE Mb0186c|M.bovis_AF2122/97 KAIRTVRFWMAPIATTLALMSALAALYLG--GILNPMTNLRHFPIALVNE MMAR_0423|M.marinum_M KSLRTVRFWTAPVVITLALMSALAALYLG--GILNPTTNLRQFPIALVNE MUL_1073|M.ulcerans_Agy99 KSLRTVRFWTAPVVIILALMSALAALYLG--GILNPTTNLRQFPIALVNE MLBr_02600|M.leprae_Br4923 KAIRTVRFWASPIVITLSLMSALAALYLG--GILNPTTNLQHFPLAVVNE MAV_5003|M.avium_104 KAVRTVRFWAAPLVITLALMSALCALYLG--GILNPTTNLRHFPIAVVNE Mflv_1752|M.gilvum_PYR-GCK NASREIVNQVNAEIGERSVGTVVTGLTDAGQGLQQAADGAQQLATGLGTA Mvan_4995|M.vanbaalenii_PYR-1 NASREVLNQVNAKIGERTVGTVLTGLTDAGQGLEQAADGAQQLATGLDTA MSMEG_5644|M.smegmatis_MC2_155 NAAREVINQINARIGERTVGTVLTGLTDAGEGLIKAADGAQQLADGNAAA TH_0090|M.thermoresistible__bu -----VLNVVNARVGQQSVETVLTGLTDAGEGLTQAADGADRLHTGLVAA MAB_4762|M.abscessus_ATCC_1997 TAIDQVLNAVSTRISGQAVNQVLSVVVSSGAGIQQAADGARQLADGAAKV : . :: .: : . *: :. . :: . Rv0180c|M.tuberculosis_H37Rv DAGPA-----------GQQIVDGLVSGLDKNKFDIRVVSPDEARRLLDTA Mb0186c|M.bovis_AF2122/97 DAGPA-----------GQQIVDGLVSGLDKNKFDIRVVSPDEARRLLDTA MMAR_0423|M.marinum_M DAGPA-----------GKQIVDGIVAGLDKNKFDVRVVDHEQAQRLLDRA MUL_1073|M.ulcerans_Agy99 DAGPA-----------GKQIVDGIVAGLDKNKFDVRVVDHEQAQRLLDRA MLBr_02600|M.leprae_Br4923 DAGPA-----------GAQIVEGLLAGLDKNKFDVRVVSCREAQQLLDSA MAV_5003|M.avium_104 DAGPG-----------GAQIVDRLATGLDRNKFDIRVLSRDEAKHQLDTG Mflv_1752|M.gilvum_PYR-GCK DDGARRLAGGADTLSSGLNTAQDGSAELAAGTQRLATSIDKTTGPLLEML Mvan_4995|M.vanbaalenii_PYR-1 DDGAQRLATGAGTLSSGLDSARAGSAQLAAGTRQLAGTVDTATGPLLEML MSMEG_5644|M.smegmatis_MC2_155 NDGAQRLASGADALTAGLVTARDGSAQLAAGTRQLSTAVTTATDPLLHVL TH_0090|M.thermoresistible__bu DDGAHDLSVGADALAAGLVTARDGAAQLAAGTGQLAAAVDTAIDPLLHTL MAB_4762|M.abscessus_ATCC_1997 DDGAGQLAT-------GLHTARPGSAQLATGAKQLSDGINQATDPLLTVT : *. * . : * . : * Rv0180c|M.tuberculosis_H37Rv AVYGSALIPPTFSSQLRDFGASAVTPTRTDRPAITISTNPRAGTLAASIA Mb0186c|M.bovis_AF2122/97 AVYGSALIPPTFSSQLRDFGASAVTPTRTDRPAITISTNPRAGTLAASIA MMAR_0423|M.marinum_M QVYGSAVIPPTFSSQLRDFAVSAVQPGSTDRPVITISTNPRAGTLGASIA MUL_1073|M.ulcerans_Agy99 QVYGSAVVPPTFSSQLRDFAVSAVQPGSTDRPVITIFTNSRAGTLGASIA MLBr_02600|M.leprae_Br4923 GVYGSAVIPPSFSSQLRDFGTSAVLPTHADRPVIMVSTNPRAGALGSSIA MAV_5003|M.avium_104 RVYGSLLIPPSFSSKLRDFATSAVSPARPDKPSITVSTNPRAGTLGASIA Mflv_1752|M.gilvum_PYR-GCK DRVGAVGLNPDDVAVAAQHLSGAVRSTTDRLAALNVNTAQAAAIVDHSVG Mvan_4995|M.vanbaalenii_PYR-1 DRVAGLSLNPDEVAVAAQHLSGAVRSTTDRIAALNVNSAQAAAIVDQAVG MSMEG_5644|M.smegmatis_MC2_155 DRVGDLGLDPDEVGRAAQRLSGAVRSTTDRIAALNIDQAQAAAIVDQAVN TH_0090|M.thermoresistible__bu DRVGALGLDPDEVGAVATRLSGAVRSTTERIAALHIDQHHAAAVLDQAVT MAB_4762|M.abscessus_ATCC_1997 KAVANIGGSTDKLQQGAE----ALRQANDQIDGIAKAQDSAANALTAVID . . *: : * : : Rv0180c|M.tuberculosis_H37Rv GQTLTRALTVVNGKVGERLTAEVAAQTGGVALAGAAAAGLAS-PIDVKST Mb0186c|M.bovis_AF2122/97 GQTLTRALTVVNGKVGERLTAEVAAQTGGVALAGAAAAGLAS-PIDVKST MMAR_0423|M.marinum_M GQTLTQAMAAANSKVGERVTAEVAAQTGGAPLSGASALGLAS-PIDVKTT MUL_1073|M.ulcerans_Agy99 GQTLTQAMAAANSKVGERVTAEVAAQTGGAPLSGASALGLAS-PIDVKTT MLBr_02600|M.leprae_Br4923 GQTLTQAITMVNSKAGQRLTAEVAAQTGGAHLTGAAALGLTS-PIDIKLA MAV_5003|M.avium_104 GQTLNSAMGTANGIAAQRVMAEVTAQTGGTPLPGATQAGLSS-PIEIQSV Mflv_1752|M.gilvum_PYR-GCK FLQSSPDPAVRDAGHALAGAQRLLRAQGIDPTTDEGLIRLRDSASRLESE Mvan_4995|M.vanbaalenii_PYR-1 FLQANPDPAVRDAGHALAGAQRLLRAQNIDPTTDEGLIRLRDSASRLEGE MSMEG_5644|M.smegmatis_MC2_155 FLRNSPDPTARDTGEFLAGAHRILTSRGIDPTTDDGLIKLRDSAAELENE TH_0090|M.thermoresistible__bu FLRTNPDPAAHHLGEALAGVQRMLRAQGIDPATDEGLIRLRDSAAQLESE MAB_4762|M.abscessus_ATCC_1997 QLAGRQDPAAN----TLRGIQDQLREHQFTPQVRQQLTDAENASIAMTET . . : Rv0180c|M.tuberculosis_H37Rv AYNPLP-------------------------NGTGNGLSAFYYALLLLLA Mb0186c|M.bovis_AF2122/97 AYNPLP-------------------------NGTGNGLSAFYYALLLLLA MMAR_0423|M.marinum_M VYNPLP-------------------------NGTGNGLSAFYYALLLLLA MUL_1073|M.ulcerans_Agy99 VYNPLP-------------------------NGTGNGLSAFYYALLLLLA MLBr_02600|M.leprae_Br4923 IYNPLP-------------------------NGTGNGLSAFYYALLLLLT MAV_5003|M.avium_104 VYNPLP-------------------------NGTGNGLSAFYYALLLLLA Mflv_1752|M.gilvum_PYR-GCK LGDPQSTLRVFLARALNGGLRSDVASLRDGVDQLNSGAQRLADGLVQLAG Mvan_4995|M.vanbaalenii_PYR-1 LGDPNSKLRVFLARALDGGLRSDVAKLRDGVDELNSGAQRLNAGLVQLAN MSMEG_5644|M.smegmatis_MC2_155 LGDPNSKMRTFISKALNGGLRADVVKLRDGAQQLNSGAQALNSGLVQLTN TH_0090|M.thermoresistible__bu LADPNSRLRTFLTAALDGGLRGEVVRLRDGVNRLDTGARQLSAGLVRLAD MAB_4762|M.abscessus_ATCC_1997 LRGPGSPLKSALDQVGGKGQ-----ELTNKLTQLRNGAQQLATGNAQLSS .* . .* : . * Rv0180c|M.tuberculosis_H37Rv G-----------FTGSIVVSTLVDSMLGYVPAEFGPVYRFAEQVN----- Mb0186c|M.bovis_AF2122/97 G-----------FTGSIVVSTLVDSMLGYVPAEFGPVYRFAEQVN----- MMAR_0423|M.marinum_M G-----------FTGSIVVSTLVDSLLGYVPAEFGPVYRFAEQVN----- MUL_1073|M.ulcerans_Agy99 G-----------FTGSIVVSTLVDSLLGYVPAEFGPVYHFAEQVN----- MLBr_02600|M.leprae_Br4923 G-----------FTGSIVVSTLVDSMLGYIPTEVGPVYHYAEQIN----- MAV_5003|M.avium_104 G-----------FTGSIVVSTLVDALLGYVPAEFGPVYRFAEQVR----- Mflv_1752|M.gilvum_PYR-GCK GGRELAAGAHDLAEGTGKLRAGGQELATRLRDGSTQIPSWTPQQRTEVAR Mvan_4995|M.vanbaalenii_PYR-1 GGRELSSGASQLADGTEKLRAGGQELATKLRQGTAEVPSWTPQQRTEMAQ MSMEG_5644|M.smegmatis_MC2_155 GGRQLSNGANELAAGTEKLETGSRQLATALRDGSTQVPSWTPQQRTEVAR TH_0090|M.thermoresistible__bu GGQQLATGAGRLADGTGQLRAGSRELADALRDGSTQVPSWTPEQRSDVAA MAB_4762|M.abscessus_ATCC_1997 GIAKMDDGAQQLKSGTAQLRSGSAELATKLTDGAKQVPTWSNQQKNAIAD * *: : : : : : :: : . Rv0180c|M.tuberculosis_H37Rv -----------------------ISRFRTLLVKWAVMVVLALLTSGVYLA Mb0186c|M.bovis_AF2122/97 -----------------------ISRFRTLLVKWAVMVVLALLTSGVYLA MMAR_0423|M.marinum_M -----------------------ISRFRTLLLKWGLMTVLALLTSAVYMA MUL_1073|M.ulcerans_Agy99 -----------------------ISRFRTLLLKWGLMTVLALLTSAVYMA MLBr_02600|M.leprae_Br4923 -----------------------ISRFHTLVVKWGLMVVLALITSAVYLA MAV_5003|M.avium_104 -----------------------ISRFQTLLLKWAMMVLLGLLTSAVYLA Mflv_1752|M.gilvum_PYR-GCK TLAAPVGADLVTDNPAPTFGTGFAPFFLPLALFIGALIVWMLLSPLRSRP Mvan_4995|M.vanbaalenii_PYR-1 TLVTPVGLDLVNTNPAATFGTGFAPFFMPLALFIGALIIWMLLTPLQSRP MSMEG_5644|M.smegmatis_MC2_155 TLSAPVALDIETHNPAVTFGTGFAPFFLPLALFIGALIIWMLLKPLQTRP TH_0090|M.thermoresistible__bu AMAAPVELDLVTHNPAATFGTGFAPFFLPLALFIGALIVWMLLTPLQSRP MAB_4762|M.abscessus_ATCC_1997 TIGGPVHLETAHENAAPNFGTGMAPFFVTLALFFGALVLWMILRPLQTRA . * .* : . : : :: . . Rv0180c|M.tuberculosis_H37Rv IAHGLGMPIPLGWQVWLYGVFAIIAVGVTSSSLIAVLGSMG--LLVSMLI Mb0186c|M.bovis_AF2122/97 IAHGLGMPIPLGWQVWLYGVFAIIAVGVTSSSLIAVLGSMG--LLVSMLI MMAR_0423|M.marinum_M IAHGLGMPIPAGWKLWLYGVFAITAVGVTSSSLIAVLGSMG--LLASMLV MUL_1073|M.ulcerans_Agy99 IAHELGMPIPAGWKLWLYGVFAITAVGVTSSSLIAVLGSMG--LLASMLV MLBr_02600|M.leprae_Br4923 IAHGLGMPIPLGWQLWLYGVFAISAVGITSSSLIAGLGSMG--LLVSMFI MAV_5003|M.avium_104 IANGLGMPIDLSWELWAYGVFAIAAVGITSSSLLSVLGTAG--MLVSMLV Mflv_1752|M.gilvum_PYR-GCK IVNGLGALRVVLASFWPALLVVVCQVFVMYVVVHFGVGLQAKHPVATVGF Mvan_4995|M.vanbaalenii_PYR-1 IVNGLGALRVVLASYWPGLLVAVCQVVVMYAVVHFGVGLQAEYPLATVAF MSMEG_5644|M.smegmatis_MC2_155 VVNGLGALRVVLASYWPGLLIAVCQVVVMYVVVHFGVGLQAKYPLATVGF TH_0090|M.thermoresistible__bu IVNGLGALRVVLASFWPGLLIVVAQVVVMYAVVHFGVGLKAEHPLATVAF MAB_4762|M.abscessus_ATCC_1997 IAAEVLPLRVALSSYLPAATIGIFQAIILYCVVRFALGMHAAHPVAMLGF :. : . . : . : : :* . :. : . Rv0180c|M.tuberculosis_H37Rv FVILGLPSAGATVPLEAVPAFFRWLAQFEPMHQVFLGVRSLLYLNGNADA Mb0186c|M.bovis_AF2122/97 FVILGLPSAGATVPLEAVPAFFRWLAQFEPMHQVFLGVRSLLYLNGNADA MMAR_0423|M.marinum_M FVILGLPSAGATVPLEAVPPFFRWLAKFEPMHQVFLGVRSLLYLNGQPES MUL_1073|M.ulcerans_Agy99 FVTLGLPSAGATVPLEAVPPFFRWLAKFEPMHQVFLGVRSLLYLNGQPES MLBr_02600|M.leprae_Br4923 FMILGLPSAGATVPLEAVPPFFRWLSEFEPLHQLFLGVRSLLYLKGHADS MAV_5003|M.avium_104 FVIFGLPSAGATVPLEATPPLFRWLAEFEPMHQVFLGTRSLLYFGGRGDA Mflv_1752|M.gilvum_PYR-GCK LVLIGGTFLALIQAFNALFGVAVGRVVTLAFLMLQLVSAGGIYPVETTAK Mvan_4995|M.vanbaalenii_PYR-1 LVLIAATFLAMIQAFNAVFGVAVGRVVTLAFLMLQLVSAGGIYPVETTAK MSMEG_5644|M.smegmatis_MC2_155 LILVAATFLALIQAFNALFGVSVGRVVTLAFLMLQLVSAGGIYPVETTAK TH_0090|M.thermoresistible__bu LILIGATFLALIQAFNAVFGVAVGRVVTLAFLMLQLVSAGGIYPVETTAK MAB_4762|M.abscessus_ATCC_1997 MVLISFAFVAATQAINALVGPAVGRVLLMALLMLQLVSAGGMYPVETTSR :: .. . . .::* .: : * . :* Rv0180c|M.tuberculosis_H37Rv GLSQALTMTSIGLIIG----LLLGGFITHLYDRSSFHRIPGAVEMAIAVE Mb0186c|M.bovis_AF2122/97 GLSQALTMTSIGLIIG----LLLGGFITHLYDRSSFHRIPGAVEMAIAVE MMAR_0423|M.marinum_M GLSHALLMTAIGLVIG----LLLGGLTTHLYDRKGFHRIPGAVEMAIAAE MUL_1073|M.ulcerans_Agy99 GLSHALLMTAIGLVIG----LLLGGLTTHLYDRKGFHRIPGAVEMAIAAE MLBr_02600|M.leprae_Br4923 GMSQALFMTALGMAIG----LLLGGVVTRIYDRGGCHRIPGAVGMAIAEW MAV_5003|M.avium_104 GLSQALTMTSAGLVIG----LLLGGIVTHLYDRKGFHRIPGAVGFAIAQD Mflv_1752|M.gilvum_PYR-GCK PFQILHPFDPMTYAVNGLRQLTVGGVDSRLWVGIGVLAGLLAASLATSAW Mvan_4995|M.vanbaalenii_PYR-1 PFQIIHPFDPMTYAVNGLRQLTVGGVDSRLWIAIAVLAGLLVASLAASAW MSMEG_5644|M.smegmatis_MC2_155 PFQILHPVDPMTYAVNGLRQVIVGGVDSRLWIAIVVLTGLLAVSLAGSAW TH_0090|M.thermoresistible__bu PFQIIHPFDPMTYAVNGLRQLIVGGVDQRLWIAIAVLAGLLAASTAASAW MAB_4762|M.abscessus_ATCC_1997 PFQILHKYDPMTYGVNGLRQLILGGIDGRLWQAVITLLFILLGGLLITSL :. . :. : :**. ::: : Rv0180c|M.tuberculosis_H37Rv HQAQYQARQSAR----------------------ESSSEQP-- Mb0186c|M.bovis_AF2122/97 HQAQYQARQSAR----------------------ESSSEQP-- MMAR_0423|M.marinum_M HQAQHQAKERARDRD-----------------STESSSEET-- MUL_1073|M.ulcerans_Agy99 HQAQHHAKERARDRD-----------------STESSSEET-- MLBr_02600|M.leprae_Br4923 HQAQHQARLRPNKSGKRPNVI-----------PTQPKCHLPVI MAV_5003|M.avium_104 HQAQHQARRGKSTQPPDSPVEPETPAEPESPDEPESPSAQT-- Mflv_1752|M.gilvum_PYR-GCK AARRNRQYTVDR---------------------LRPPIEV--- Mvan_4995|M.vanbaalenii_PYR-1 SARRNRQYTMER---------------------LHPPIEV--- MSMEG_5644|M.smegmatis_MC2_155 AARRNRQYTMDR---------------------LRPPIEV--- TH_0090|M.thermoresistible__bu AARRNRQYTMQR---------------------LHPPIEV--- MAB_4762|M.abscessus_ATCC_1997 SARRNQLWNLTR---------------------LLPSIKM--- : : .