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STATAPAQHAAPAHEPPAAVRVTGIIVVVTIAIVIFAIAFALPATRAKPVDVPIGVAGPQAATSQVAERL EQQAPGAFAVTYYPGEQALRGAILDRNVYGGIAFGPEGPALLTATGASPAVAQLLTQIGSGISAQSGIAL RTEDLAPPTSGDPRGTGLAASALPITLAGLLPAFALVLALKHEVWTRLIAMIAFSAVAGVTIAALLRYVF GSIDENFWGVSAGLMLGIAAAGLVVLGLGSLFGRVGLGIGALLAVLVGNPLSGLTAAPEMLPGGTLGQLL PQGANATLLRSTAYFGGAGAVTAIVVLCCWAALGTVMVVIAALRQARSNRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0720 | - | - | 100% (332) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_3573 | - | 3e-24 | 27.43% (339) | integral membrane protein, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0535 | gabP | 0.0001 | 30.67% (150) | GABA permease GabP |
| M. gilvum PYR-GCK | Mflv_0254 | - | 1e-112 | 63.33% (330) | hypothetical protein Mflv_0254 |
| M. tuberculosis H37Rv | Rv0522 | gabP | 0.0001 | 30.67% (150) | GABA permease GabP |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3714 | - | 9e-07 | 32.45% (151) | hypothetical protein MMAR_3714 |
| M. avium 104 | MAV_3322 | - | 1e-05 | 24.91% (273) | ABC transporter efflux protein, DrrB family protein |
| M. thermoresistible (build 8) | TH_2357 | - | 1e-117 | 66.07% (333) | integral membrane protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0640 | - | 1e-114 | 64.46% (332) | hypothetical protein Mvan_0640 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0720|M.smegmatis_MC2_155 --------------------------------------------------
TH_2357|M.thermoresistible__bu --------------------------------------------------
Mflv_0254|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0640|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0535|M.bovis_AF2122/97 --------------------------------------------------
Rv0522|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3322|M.avium_104 --------------------------------------------------
MMAR_3714|M.marinum_M MSGALGSTREITTRGIILGGLITLVFTAANVYLGLKVGLTFATSIPAAVI
MSMEG_0720|M.smegmatis_MC2_155 -----------------MSTATAP--AQHAAPAHEPPAAVR-------VT
TH_2357|M.thermoresistible__bu -----------------MTTQSAPPNDRSTIRRHEQPAAVR-------AT
Mflv_0254|M.gilvum_PYR-GCK -----------------MSSAVSH--RVTHAHAHHPPAGAR-------AA
Mvan_0640|M.vanbaalenii_PYR-1 -----------------MASSVTS--PRHTVTVHEPPAAAR-------AA
Mb0535|M.bovis_AF2122/97 -----------MIAIGGVIGAGLFVGSGVVIRATGPAAFLTY----ALCG
Rv0522|M.tuberculosis_H37Rv -----------MIAIGGVIGAGLFVGSGVVIRATGPAAFLTY----ALCG
MAV_3322|M.avium_104 -----------------MTDSGVFP--VGTFTPNPRPSAVP---------
MMAR_3714|M.marinum_M SMGVLRLFANHSIVENNIVQTIASAAGTLSAIIFVLPALIMIGWWSGFPY
: .:
MSMEG_0720|M.smegmatis_MC2_155 GIIVVVTIAIVIFAIAFALPATRAKPVDVPIG-----------------V
TH_2357|M.thermoresistible__bu GIVVVLTVAIAIIAIAFAWPASRSAPGDLPIG-----------------V
Mflv_0254|M.gilvum_PYR-GCK GIVLAITALLAVVTVAFALPATRSAPHDVPIG-----------------A
Mvan_0640|M.vanbaalenii_PYR-1 GIIVAITALLALVAIAFALPAARSGPHHVPIG-----------------A
Mb0535|M.bovis_AF2122/97 ALIVLVMRMLGEMAAANPSTGAFADYAAKALGGWAGFSVGWLYWYFWVIV
Rv0522|M.tuberculosis_H37Rv ALIVLVMRMLGEMAAANPSTGAFADYAAKALGGWAGFSVGWLYWYFWVIV
MAV_3322|M.avium_104 ----------KMLAAQYGLELKLLLRNGEQLL------------------
MMAR_3714|M.marinum_M WTTVAVCGFGGLLGVMYSIPLRRALVTGSDLPYPEGVAGAEVLKIGASAR
. :
MSMEG_0720|M.smegmatis_MC2_155 AGPQAATS---------------QVAERLEQQAPGAFAVTYYPGEQALRG
TH_2357|M.thermoresistible__bu AAPPPVTA---------------QITARLAEQAPDAFDVRAFDDDAALRA
Mflv_0254|M.gilvum_PYR-GCK AGPQSAGG---------------RIADVLEQKAPGAFDVTFYPGEEALRD
Mvan_0640|M.vanbaalenii_PYR-1 AGPQVASG---------------QISTVLDAKMPGAFEVTFYPGEAALAD
Mb0535|M.bovis_AF2122/97 VGFEAVAGGKVLTYWIDAPLWLASLCLMMMMTATNLVSVSSFGEFEFWFA
Rv0522|M.tuberculosis_H37Rv VGFEAVAGGKVLTYWIDAPLWLASLCLMMMMTATNLVSVSSFGEFEFWFA
MAV_3322|M.avium_104 ------------------------LTMFIPITLLVGLTLLPLGSFGQHRA
MMAR_3714|M.marinum_M GAEENRRGLSVIALGAVTAAGYSLLAALKVISNSLAVTFRLGSGATMAGA
: . .
MSMEG_0720|M.smegmatis_MC2_155 AILDRNVYGGIAFG--------PEG---PALLTATGA-------------
TH_2357|M.thermoresistible__bu AIRDREVYGGLSIG--------AGP---PTLLIATGG-------------
Mflv_0254|M.gilvum_PYR-GCK AIRRGDVYGGIALP--------GSPGDQPAMLIATQA-------------
Mvan_0640|M.vanbaalenii_PYR-1 AIRNRDVYGGFVMP--------AQPGQPPALLLASGG-------------
Mb0535|M.bovis_AF2122/97 GVKVATIVGFLVLGTAFAFGLLPGHGMDFSNLSAHGGF------------
Rv0522|M.tuberculosis_H37Rv GVKVATIVGFLVLGTAFAFGLLPGHGMDFSNLSAHGGF------------
MAV_3322|M.avium_104 ATFTPVIMALAVIS------------------TAFTG-------------
MMAR_3714|M.marinum_M SLSLALVGVGHLVGLGVGIAMIVGVLISYGVLLPMRTAGQLPQDGALADF
. : . .
MSMEG_0720|M.smegmatis_MC2_155 ----------SPAVAQLLTQIGSGISAQSG---IALRTEDLAPPTSGDPR
TH_2357|M.thermoresistible__bu ----------SPAVAQLLTQMAGGIAEQSG---MPLRTEDLAAPPPDDPR
Mflv_0254|M.gilvum_PYR-GCK ----------GPAVAQVLTQLGTEISRQTG---MPLTTEDLAPPTARDPR
Mvan_0640|M.vanbaalenii_PYR-1 ----------SPMVAQLLTQIGAELSRQTG---TALRTEDLAPPTARDPR
Mb0535|M.bovis_AF2122/97 ---------FPDGVGAVFAAIVVAIFSMTGTEVVTIAAAEAPDPQRAVQR
Rv0522|M.tuberculosis_H37Rv ---------FPDGVGAVFAAIVVAIFSMTGTEVVTIAAAEAPDPQRAVQR
MAV_3322|M.avium_104 ------------------QAIAVAFDRRYG---ALKRLGATPLPVWGIIA
MMAR_3714|M.marinum_M VSRTFSSDVRFIGAGAIAVAAVWTFLKIAGPIMAGIAEAAVSARTRRRGE
: * .
MSMEG_0720|M.smegmatis_MC2_155 GTGLAASALPITLAGLLPAFALVLALK---------------------HE
TH_2357|M.thermoresistible__bu GVGLAASALPITLAGLLPAIALVLALR---------------------RE
Mflv_0254|M.gilvum_PYR-GCK GVGLAASALPLTLAGILPAIALLLALR---------------------RE
Mvan_0640|M.vanbaalenii_PYR-1 GAALAASALPITLAGILPAIALVLALR---------------------RE
Mb0535|M.bovis_AF2122/97 AMSTVVARIVIFFVGSVFLLTVILPWNSLELGASPYVAALRHMGIGGADQ
Rv0522|M.tuberculosis_H37Rv AMSTVVARIVIFFVGSVFLLTVILPWNSLELGASPYVAALRHMGIGGADQ
MAV_3322|M.avium_104 GKSLAVVTVVFLQAILLGAIGFALGWR-----------------------
MMAR_3714|M.marinum_M AVDLHERDIPIQVVGLVVLVSLIPIGLLLG----------DFTDHTPIAG
. : : . : . .
MSMEG_0720|M.smegmatis_MC2_155 VWTRLIAMIAFSAV-AGVTIAALLRYVFGSIDEN----------------
TH_2357|M.thermoresistible__bu VWTRFAATVVFAAL-AAWTIALLLRFVFGSITDN----------------
Mflv_0254|M.gilvum_PYR-GCK VWIRYAAAVVFSGL-AGITTAALLRFTLGAIDHN----------------
Mvan_0640|M.vanbaalenii_PYR-1 VWTGFAAAVVFSGV-AGVTIAALLRYVLGSVDGN----------------
Mb0535|M.bovis_AF2122/97 IMNAVVLTAVLSCLNSGLYTASRMLFVLAARQEAPAQLVKV---------
Rv0522|M.tuberculosis_H37Rv IMNAVVLTAVLSCLNSGLYTASRMLFVLAARQEAPAQLVKV---------
MAV_3322|M.avium_104 --------PALAALALGAAVIALGTAVFA---------------------
MMAR_3714|M.marinum_M RAGSIIAVSLLLIVTIGLVVASVCGYMAGLIGSSNSPISGVGILVVLLAA
: : . .
MSMEG_0720|M.smegmatis_MC2_155 --------------------------------------------------
TH_2357|M.thermoresistible__bu --------------------------------------------------
Mflv_0254|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0640|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0535|M.bovis_AF2122/97 --------------------------------------------------
Rv0522|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3322|M.avium_104 --------------------------------------------------
MMAR_3714|M.marinum_M LLIKWTYGPASDAQTPALVAYAVFTAAVIFGVATISNDNLQDLKTGQLVG
MSMEG_0720|M.smegmatis_MC2_155 ------FWGVSAGLMLGIAAAGLVVLGLGSLFGRVGLGIG----------
TH_2357|M.thermoresistible__bu ------FWGVTAGLTLGILAAGLTVLGLGSVFGRAGLAIG----------
Mflv_0254|M.gilvum_PYR-GCK ------FWAVAAALSLGVAAAVLSVLGLGSLFGRAGLGAG----------
Mvan_0640|M.vanbaalenii_PYR-1 ------FWGIAAGLTLGVAAALLFMFGLGSLFGRAGLAVG----------
Mb0535|M.bovis_AF2122/97 NRRGVPTFAIMGSSVVGFLCVIMAWVSPATVFVFLLNSSGA---------
Rv0522|M.tuberculosis_H37Rv NRRGVPTFAIMGSSVVGFLCVIMAWVSPATVFVFLLNSSGA---------
MAV_3322|M.avium_104 ----------ALGLLLGGTLRAEIVLALANLMWFVFAGLG----------
MMAR_3714|M.marinum_M ATPWKQQVALVIGVTIGAAVMAPVLQLMQSAFGFQGAPGATGNALAAPQA
. :* . : .
MSMEG_0720|M.smegmatis_MC2_155 --------------------------ALLAVLVGNPLSGLTAAPEMLPG-
TH_2357|M.thermoresistible__bu --------------------------ALLAILLGNPLSGLNAAPELLPRG
Mflv_0254|M.gilvum_PYR-GCK --------------------------AALALLVGNPLSGLASAPEMLPAG
Mvan_0640|M.vanbaalenii_PYR-1 --------------------------SLLALLVGNPLSGLASAPEMLPAG
Mb0535|M.bovis_AF2122/97 ---------------------VILFVYLLIALSQIVLRRQTSGQNLGVRM
Rv0522|M.tuberculosis_H37Rv ---------------------VILFVYLLIALSQIVLRRQTSGQNLGVRM
MAV_3322|M.avium_104 ---------------------------ALTVDSGVIPAGVKWAARLTPSG
MMAR_3714|M.marinum_M ALISALAKGVFGGSLNWSLVGLGALIGIVVVVVDEVLTRTTATLRLPPLA
: .:
MSMEG_0720|M.smegmatis_MC2_155 --------------------------------------------------
TH_2357|M.thermoresistible__bu W-------------------------------------------------
Mflv_0254|M.gilvum_PYR-GCK W-------------------------------------------------
Mvan_0640|M.vanbaalenii_PYR-1 W-------------------------------------------------
Mb0535|M.bovis_AF2122/97 W-------------------------------------------------
Rv0522|M.tuberculosis_H37Rv W-------------------------------------------------
MAV_3322|M.avium_104 --------------------------------------------------
MMAR_3714|M.marinum_M VGMGMYLPISLTLVIPVGAVLGRIYDSWAQRSGDEDESKRRMGVMLATGL
MSMEG_0720|M.smegmatis_MC2_155 ---------GTLGQLLPQGANATLLRSTAYFGGAGAVTAIVVLCCWAALG
TH_2357|M.thermoresistible__bu ---------GQLGQLLPQGANATLLRSTAYFDGAGATTAIWVLVCWVLVG
Mflv_0254|M.gilvum_PYR-GCK ---------GQFGQLLPQGATATLLRSAAAFGGAGATTAITVLTCWIVFG
Mvan_0640|M.vanbaalenii_PYR-1 ---------GQLGQLLPQGATATLLRSTAAFEGAGAATAIVVLTCWTLAG
Mb0535|M.bovis_AF2122/97 ---------LFPGLSIVTVTGIVAVLARMAFDYAARSQLWLSLLSWAVVV
Rv0522|M.tuberculosis_H37Rv ---------LFPGLSIVTVTGIVAVLARMAFDYAARSQLWLSLLSWAVVV
MAV_3322|M.avium_104 --------------ALTEALSRAMTLSADWFG-------MAVLVAWGALG
MMAR_3714|M.marinum_M IVGESLFGVAFAGIVVATGTEDPLAILGDGFTHWAELLGLFVFAAMIALL
: * : .
MSMEG_0720|M.smegmatis_MC2_155 TVMVVIAALRQARSNRA----------
TH_2357|M.thermoresistible__bu TALIAVAALRQRRTAEPHPAEMH----
Mflv_0254|M.gilvum_PYR-GCK TALVAAAAVRARAVPAQ----------
Mvan_0640|M.vanbaalenii_PYR-1 TALTVTAAVRHRKQAPA----------
Mb0535|M.bovis_AF2122/97 GCYLVTTLVRRPLNRPW----------
Rv0522|M.tuberculosis_H37Rv GCYLVTTLVRRPLNRPW----------
MAV_3322|M.avium_104 ----ALGALRWFRFT------------
MMAR_3714|M.marinum_M YRYVRAAASYRPTTPGQEPEPLSGRAG