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M. thermoresistible (build 8) TH_2357 (-)

annotation: integral membrane protein
coordinates: 4629058 - 4630086
length: 343

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2357--100% (343)integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0186c-5e-0726.70% (221) transmembrane protein
M. gilvum PYR-GCKMflv_0254-1e-10761.95% (318) hypothetical protein Mflv_0254
M. tuberculosis H37RvRv0180c-5e-0726.70% (221) transmembrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_5003-4e-0726.15% (260) ABC-2 type transporter family protein
M. smegmatis MC2 155MSMEG_0720-1e-11766.07% (333) integral membrane protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0640-1e-11162.16% (333) hypothetical protein Mvan_0640

CLUSTAL 2.0.9 multiple sequence alignment


TH_2357|M.thermoresistible__bu      MTTQSAPPNDRSTIRRHEQPAAVRATGIVVVLTVAIAIIAIAFAWP---A
MSMEG_0720|M.smegmatis_MC2_155      MSTATAP--AQHAAPAHEPPAAVRVTGIIVVVTIAIVIFAIAFALP---A
Mflv_0254|M.gilvum_PYR-GCK          MSSAVSH--RVTHAHAHHPPAGARAAGIVLAITALLAVVTVAFALP---A
Mvan_0640|M.vanbaalenii_PYR-1       MASSVTS--PRHTVTVHEPPAAARAAGIIVAITALLALVAIAFALP---A
Mb0186c|M.bovis_AF2122/97           MSQAQPRPAAPNPKRNVKAIRTVRFWMAPIATTLALMSALAALYLGGILN
Rv0180c|M.tuberculosis_H37Rv        MSQAQPRPAAPNPKRNVKAIRTVRFWMAPIATTLALMSALAALYLGGILN
MAV_5003|M.avium_104                MARSHPQHAAPNPNRNIKAVRTVRFWAAPLVITLALMSALCALYLGGILN
                                    *:   .           .    .*     :. *  :     *:       

TH_2357|M.thermoresistible__bu      SRSAPGDLPIGVAAPPP--VTAQITARLAEQAP-DAFDVRAFDDDAALRA
MSMEG_0720|M.smegmatis_MC2_155      TRAKPVDVPIGVAGPQA--ATSQVAERLEQQAP-GAFAVTYYPGEQALRG
Mflv_0254|M.gilvum_PYR-GCK          TRSAPHDVPIGAAGPQS--AGGRIADVLEQKAP-GAFDVTFYPGEEALRD
Mvan_0640|M.vanbaalenii_PYR-1       ARSGPHHVPIGAAGPQV--ASGQISTVLDAKMP-GAFEVTFYPGEAALAD
Mb0186c|M.bovis_AF2122/97           PMTNLRHFPIALVNEDAGPAGQQIVDGLVSGLDKNKFDIRVVSPDEARR-
Rv0180c|M.tuberculosis_H37Rv        PMTNLRHFPIALVNEDAGPAGQQIVDGLVSGLDKNKFDIRVVSPDEARR-
MAV_5003|M.avium_104                PTTNLRHFPIAVVNEDAGPGGAQIVDRLATGLDRNKFDIRVLSRDEAKH-
                                    . :   ..**. .         ::   *      . * :     : *   

TH_2357|M.thermoresistible__bu      AIRDREVYGGLSIG----------------AGP---PTLLIATG------
MSMEG_0720|M.smegmatis_MC2_155      AILDRNVYGGIAFG----------------PEG---PALLTATG------
Mflv_0254|M.gilvum_PYR-GCK          AIRRGDVYGGIALP----------------GSPGDQPAMLIATQ------
Mvan_0640|M.vanbaalenii_PYR-1       AIRNRDVYGGFVMP----------------AQPGQPPALLLASG------
Mb0186c|M.bovis_AF2122/97           LLDTAAVYGSALIPPTFSSQLRDFGASAVTPTRTDRPAITISTNPRAGTL
Rv0180c|M.tuberculosis_H37Rv        LLDTAAVYGSALIPPTFSSQLRDFGASAVTPTRTDRPAITISTNPRAGTL
MAV_5003|M.avium_104                QLDTGRVYGSLLIPPSFSSKLRDFATSAVSPARPDKPSITVSTNPRAGTL
                                     :    ***.  :                       *::  ::       

TH_2357|M.thermoresistible__bu      GSPAVAQLLT------------QMAGGIAEQSG---------------MP
MSMEG_0720|M.smegmatis_MC2_155      ASPAVAQLLT------------QIGSGISAQSG---------------IA
Mflv_0254|M.gilvum_PYR-GCK          AGPAVAQVLT------------QLGTEISRQTG---------------MP
Mvan_0640|M.vanbaalenii_PYR-1       GSPMVAQLLT------------QIGAELSRQTG---------------TA
Mb0186c|M.bovis_AF2122/97           AASIAGQTLTRALTVVNGKVGERLTAEVAAQTGGVALAGAAAAGLASPID
Rv0180c|M.tuberculosis_H37Rv        AASIAGQTLTRALTVVNGKVGERLTAEVAAQTGGVALAGAAAAGLASPID
MAV_5003|M.avium_104                GASIAGQTLNSAMGTANGIAAQRVMAEVTAQTGGTPLPGATQAGLSSPIE
                                    ... ..* *.            ::   :: *:*                 

TH_2357|M.thermoresistible__bu      LRTEDLAAPPPDDPRGVGLAASALPITLAGLLPAIAL-------------
MSMEG_0720|M.smegmatis_MC2_155      LRTEDLAPPTSGDPRGTGLAASALPITLAGLLPAFAL-------------
Mflv_0254|M.gilvum_PYR-GCK          LTTEDLAPPTARDPRGVGLAASALPLTLAGILPAIAL-------------
Mvan_0640|M.vanbaalenii_PYR-1       LRTEDLAPPTARDPRGAALAASALPITLAGILPAIAL-------------
Mb0186c|M.bovis_AF2122/97           VKSTAYNPLPNGTGNGLSAFYYALLLLLAGFTGSIVVSTLVDSMLGYVPA
Rv0180c|M.tuberculosis_H37Rv        VKSTAYNPLPNGTGNGLSAFYYALLLLLAGFTGSIVVSTLVDSMLGYVPA
MAV_5003|M.avium_104                IQSVVYNPLPNGTGNGLSAFYYALLLLLAGFTGSIVVSTLVDALLGYVPA
                                    : :    . .    .* .    ** : ***:  ::.:             

TH_2357|M.thermoresistible__bu      ----VLALRREVWTRFAATVVFAALAAWTIALLLRFVFGSITDNF-----
MSMEG_0720|M.smegmatis_MC2_155      ----VLALKHEVWTRLIAMIAFSAVAGVTIAALLRYVFGSIDENF-----
Mflv_0254|M.gilvum_PYR-GCK          ----LLALRREVWIRYAAAVVFSGLAGITTAALLRFTLGAIDHNF-----
Mvan_0640|M.vanbaalenii_PYR-1       ----VLALRREVWTGFAAAVVFSGVAGVTIAALLRYVLGSVDGNF-----
Mb0186c|M.bovis_AF2122/97           EFGPVYRFAEQVNISRFRTLLVKWAVMVVLALLTSGVYLAIAHGLGMPIP
Rv0180c|M.tuberculosis_H37Rv        EFGPVYRFAEQVNISRFRTLLVKWAVMVVLALLTSGVYLAIAHGLGMPIP
MAV_5003|M.avium_104                EFGPVYRFAEQVRISRFQTLLLKWAMMVLLGLLTSAVYLAIANGLGMPID
                                        :  : .:*       : .        . *   .  ::  .:     

TH_2357|M.thermoresistible__bu      --WGVTAGLTLGILAAGLTVLGLGSVFGRAGLAIGALLAILLGNPLSGLN
MSMEG_0720|M.smegmatis_MC2_155      --WGVSAGLMLGIAAAGLVVLGLGSLFGRVGLGIGALLAVLVGNPLSGLT
Mflv_0254|M.gilvum_PYR-GCK          --WAVAAALSLGVAAAVLSVLGLGSLFGRAGLGAGAALALLVGNPLSGLA
Mvan_0640|M.vanbaalenii_PYR-1       --WGIAAGLTLGVAAALLFMFGLGSLFGRAGLAVGSLLALLVGNPLSGLA
Mb0186c|M.bovis_AF2122/97           LGWQVWLYGVFAIIAVGVTSSSLIAVLGSMGLLVSMLIFVILGLPSAGAT
Rv0180c|M.tuberculosis_H37Rv        LGWQVWLYGVFAIIAVGVTSSSLIAVLGSMGLLVSMLIFVILGLPSAGAT
MAV_5003|M.avium_104                LSWELWAYGVFAIAAVGITSSSLLSVLGTAGMLVSMLVFVIFGLPSAGAT
                                      * :     :.: *. :   .* :::*  *:  .  : ::.* * :*  

TH_2357|M.thermoresistible__bu      AAPELLPRGWGQLGQLLPQGANATLLRSTAYFDG---AGATTAIWVLVCW
MSMEG_0720|M.smegmatis_MC2_155      AAPEMLPG--GTLGQLLPQGANATLLRSTAYFGG---AGAVTAIVVLCCW
Mflv_0254|M.gilvum_PYR-GCK          SAPEMLPAGWGQFGQLLPQGATATLLRSAAAFGG---AGATTAITVLTCW
Mvan_0640|M.vanbaalenii_PYR-1       SAPEMLPAGWGQLGQLLPQGATATLLRSTAAFEG---AGAATAIVVLTCW
Mb0186c|M.bovis_AF2122/97           VPLEAVPAFFRWLAQFEPMHQVFLGVRSLLYLNGNADAGLSQALTMTSIG
Rv0180c|M.tuberculosis_H37Rv        VPLEAVPAFFRWLAQFEPMHQVFLGVRSLLYLNGNADAGLSQALTMTSIG
MAV_5003|M.avium_104                VPLEATPPLFRWLAEFEPMHQVFLGTRSLLYFGGRGDAGLSQALTMTSAG
                                     . *  *     :.:: *        **   : *   **   *: :    

TH_2357|M.thermoresistible__bu      VLVGTALIAVAALRQRRTAEPHPAEMH-----------------------
MSMEG_0720|M.smegmatis_MC2_155      AALGTVMVVIAALRQARSNRA-----------------------------
Mflv_0254|M.gilvum_PYR-GCK          IVFGTALVAAAAVRARAVPAQ-----------------------------
Mvan_0640|M.vanbaalenii_PYR-1       TLAGTALTVTAAVRHRKQAPA-----------------------------
Mb0186c|M.bovis_AF2122/97           LIIGLLLGGFITHLYDRSSFHRIPGAVEMAIAVEHQAQYQARQS------
Rv0180c|M.tuberculosis_H37Rv        LIIGLLLGGFITHLYDRSSFHRIPGAVEMAIAVEHQAQYQARQS------
MAV_5003|M.avium_104                LVIGLLLGGIVTHLYDRKGFHRIPGAVGFAIAQDHQAQHQARRGKSTQPP
                                       *  :    :                                      

TH_2357|M.thermoresistible__bu      -------------------------
MSMEG_0720|M.smegmatis_MC2_155      -------------------------
Mflv_0254|M.gilvum_PYR-GCK          -------------------------
Mvan_0640|M.vanbaalenii_PYR-1       -------------------------
Mb0186c|M.bovis_AF2122/97           ---------ARESSSEQP-------
Rv0180c|M.tuberculosis_H37Rv        ---------ARESSSEQP-------
MAV_5003|M.avium_104                DSPVEPETPAEPESPDEPESPSAQT