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DAVIGVSVTPSTVGMVLVEGDSAADFEAVNLDLELFDVAGLDLSRARAARKEIVATVARAENVAADNGRR LRSIGVTWSDGADMQAAELVGDLNEAGFDNVVDVRFRQATDALANSIADMAGFATTVVCVFEPEGALALT VDRRDGVVDTARSRAIGSVRGLVGWLERLLAASGRVPDALVVVGSAVDLDADVDRLMPKLQAALGIPVFT PADGDLALARGAALVSARRGRFMFPDKADQQRSRWTSRQLAPAAMLLVGVVTFVVSLSLAISQQMSPREQ AFERPTRPVVNTSGTPAAVRQLPPALPAAPPPPPQAPPAAEVAEAVPPAVDPPLADVAESPVEQALPQLP PQLPLPDAATALPPPVVIPAPPTKKPLLSRIRDRLRGEPDVPEQMVIGEPPPPAEITPIPPPGAPPAPPV DDAPAPEAPPEPPPAPEAPPAADPPPPADVPPPDPPPAEPAPVEPEPAPEAPPAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3531 | - | - | 100% (476) | hypothetical protein MSMEG_3531 |
| M. smegmatis MC2 155 | MSMEG_0679 | - | 1e-43 | 29.65% (543) | hypothetical protein MSMEG_0679 |
| M. smegmatis MC2 155 | MSMEG_1195 | - | 4e-33 | 29.98% (407) | hypothetical protein MSMEG_1195 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1919 | - | 7e-44 | 34.12% (422) | hypothetical protein Mb1919 |
| M. gilvum PYR-GCK | Mflv_3300 | - | 7e-74 | 42.63% (441) | hypothetical protein Mflv_3300 |
| M. tuberculosis H37Rv | Rv1887 | - | 7e-44 | 34.12% (422) | hypothetical protein Rv1887 |
| M. leprae Br4923 | MLBr_00048 | - | 1e-09 | 28.87% (194) | hypothetical protein MLBr_00048 |
| M. abscessus ATCC 19977 | MAB_4296c | - | 2e-36 | 28.52% (526) | hypothetical protein MAB_4296c |
| M. marinum M | MMAR_2779 | - | 1e-45 | 34.07% (408) | hypothetical protein MMAR_2779 |
| M. avium 104 | MAV_2814 | - | 3e-44 | 32.88% (438) | hypothetical protein MAV_2814 |
| M. thermoresistible (build 8) | TH_3639 | - | 8e-33 | 34.88% (324) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2968 | - | 4e-46 | 34.31% (408) | hypothetical protein MUL_2968 |
| M. vanbaalenii PYR-1 | Mvan_3021 | - | 8e-79 | 43.18% (440) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1919|M.bovis_AF2122/97 --------MDTVLGLSITPTTLGWVLAEGHG-----------------AD
Rv1887|M.tuberculosis_H37Rv --------MDTVLGLSITPTTLGWVLAEGHG-----------------AD
MMAR_2779|M.marinum_M --------MDTVLGLSVTPTTVGWVLAEGHG-----------------AD
MUL_2968|M.ulcerans_Agy99 ---MRCEVLDTVLGLSVTPTTVGWVLAEGHG-----------------AD
MAV_2814|M.avium_104 ----------------MTPTTVGWVLAEGHG-----------------AD
Mflv_3300|M.gilvum_PYR-GCK --------MNAVLGLSVTPSGVGVVLVEGH-----------------DDD
Mvan_3021|M.vanbaalenii_PYR-1 --------MDAVLGLSVTPSAVGLVLVEGQ-----------------DVD
MSMEG_3531|M.smegmatis_MC2_155 --------MDAVIGVSVTPSTVGMVLVEGDSAA--------------DFE
TH_3639|M.thermoresistible__bu --------MDFVLGLSVTSAGTRAVLVEGAAG-----------------D
MAB_4296c|M.abscessus_ATCC_199 --------MDVVLGVSMTPTTARLVLVEGAG-----------------AD
MLBr_00048|M.leprae_Br4923 MAADYDKLFRLDDGAYASPDQAAEQLFDDAPLYPPPIIPTCTTTPNGEVA
:. * :.
Mb1919|M.bovis_AF2122/97 GAILDRNELELHSGRNAQAIHTAEQLAAEVLLAHEVAAAGDHRLRVIGVT
Rv1887|M.tuberculosis_H37Rv GAILDRNELELHSGRNAQAIHTAEQLAAEVLLAHEVAAAGDHRLRVIGVT
MMAR_2779|M.marinum_M GAILDHHESQLHGSRGMRIVHTAEQVADEVWHAKEVASGAGHRLRMIGVT
MUL_2968|M.ulcerans_Agy99 GAILDHHESQLHGSRGMRIVHTAEQVADEVWHAKEVASGAGHRLRMIGVT
MAV_2814|M.avium_104 GTILDHQELALHSGGAVRAASAAEQVVDEVLRVEAAAAGSDQRLRVIGVT
Mflv_3300|M.gilvum_PYR-GCK RVTLDGERFEVRRRGSATAAETSAQAAAAVLRTEAVAADLGRRVHSIGVT
Mvan_3021|M.vanbaalenii_PYR-1 GVTLDGDGFEVGGDGAAGALCTSEQATAAVRRSEAVAADLGRRVHAIGVT
MSMEG_3531|M.smegmatis_MC2_155 AVNLDLELFDVAGLDLSRARAARKEIVATVARAENVAADNGRRLRSIGVT
TH_3639|M.thermoresistible__bu GATLD--QFSSATTDDLVLALSENPTFGPALN----AAASGDGISTIGVT
MAB_4296c|M.abscessus_ATCC_199 GRIVDTDTIVVSEGE----GTTSEQVLSAIVGTRDGMLDGGHNLVSTGVV
MLBr_00048|M.leprae_Br4923 SPMPDWSEQLPPNPPAASKSPLPPMPIGSSVQPPPASSESPRAPMPVSAP
* ..
Mb1919|M.bovis_AF2122/97 ----------WNAEASAQAALLVESLTGAGFDNVVPVRRLRAIETLAQAI
Rv1887|M.tuberculosis_H37Rv ----------WNAEASAQAALLVESLTGAGFDNVVPVRRLRAIETLAQAI
MMAR_2779|M.marinum_M ----------WGDEASAQAALLLEALTDAGFDNVVPVRLLDAVETLAEAI
MUL_2968|M.ulcerans_Agy99 ----------WSDEASAQAALLLEALTDAGFDNVVPVRLVDAVETLAEAI
MAV_2814|M.avium_104 ----------WNDEASVPAALVLEALTDAGLHNVVPVRFLQAVETLAQAI
Mflv_3300|M.gilvum_PYR-GCK ----------WSDDAGTEASLLLTSLRESGYDNIVPVRLSEATDALARRI
Mvan_3021|M.vanbaalenii_PYR-1 ----------WSDDADTEASLLLKSLSEAGFDNIVPVRLSEATDALARRI
MSMEG_3531|M.smegmatis_MC2_155 ----------WSDGADMQAAELVGDLNEAGFDNVVDVRFRQATDALANSI
TH_3639|M.thermoresistible__bu ----------CSHDATTAAGLVVDDLLARGCRNVVSVSELDAAEALATGL
MAB_4296c|M.abscessus_ATCC_199 ----------WSDHA--EAAELRDSLASRGIDGVEFFSALHAGGALAKAA
MLBr_00048|M.leprae_Br4923 PRSPAASLMPISEPPQWPPAEAPEHQFAKAEPPSVPIPINEPSPAKPATP
. . .. . . . : .
Mb1919|M.bovis_AF2122/97 APVIGYEQIAVCVLEHESATVVMVDTHDG------KTQIAVKHVCRGLSG
Rv1887|M.tuberculosis_H37Rv APVIGYEQIAVCVLEHESATVVMVDTHDG------KTQIAVKHVCRGLSG
MMAR_2779|M.marinum_M APVIGYDQTAVCILEHDWATVVMVDTQDG------KTQTAVKHVRGGFDG
MUL_2968|M.ulcerans_Agy99 APVIGYDQTAVCILEHDWATVVMVDTQDG------KTQTAVKHVRGGFDG
MAV_2814|M.avium_104 APVIGYEQTAVCVLEHDWTTVVMVDSHDG------QTQTATKQVRGGFDG
Mflv_3300|M.gilvum_PYR-GCK ALVLGYRTTAVCVIEPEQLIALVVSVEDAADGTSEAVQTAVNHSVVTEDD
Mvan_3021|M.vanbaalenii_PYR-1 AKLMGYRTTAVCVIEPEQLIALVATDEG-------AVQTAVNHSVVTEED
MSMEG_3531|M.smegmatis_MC2_155 ADMAGFATTVVCVFEPEGALALTVDRRDG------VVDTARSRAIGSVRG
TH_3639|M.thermoresistible__bu ADLAGYTEIAVCIAEPDDAVIAVVGADDV------VLDGIGRAAAPAPEN
MAB_4296c|M.abscessus_ATCC_199 SSVTGYDKSALLVIEPQTATLAVVDSADG----SIVGLASEPLITGVTSG
MLBr_00048|M.leprae_Br4923 MPMTPIDGSQRTPVTSPEPSLAEFEAQPPATPKPSLLPRPMSSPPEAPRP
:
Mb1919|M.bovis_AF2122/97 LTSWLTGMFGRDAWRPAGVVVVGSDSEVSE----FSWQLERVLPVPVFAQ
Rv1887|M.tuberculosis_H37Rv LTSWLTGMFGRDAWRPAGVVVVGSDSEVSE----FSWQLERVLPVPVFAQ
MMAR_2779|M.marinum_M LNSWLTGMFDRGAWRPAAVVVVGSDTDVEE----FSWQLEKALPVPVFAQ
MUL_2968|M.ulcerans_Agy99 LNSWLTGMFDRGAWRPAAVVVVGSDTDVEE----FSWQLEKALPVPVFAQ
MAV_2814|M.avium_104 LTRWLTGMFERDGWQPGGIVVVGAHSDIDG----LSWQLEKALPVPVFVQ
Mflv_3300|M.gilvum_PYR-GCK LVGWLSTVFTRADWEPEALVLVGSGEDLED----LLPVLEDALAVPVFSP
Mvan_3021|M.vanbaalenii_PYR-1 LIGWLSSVFARADWAPEALVLVGSAEDLDG----LSPILEDALAVPVFSP
MSMEG_3531|M.smegmatis_MC2_155 LVGWLERLLAASGRVPDALVVVGSAVDLDADVDRLMPKLQAALGIPVFTP
TH_3639|M.thermoresistible__bu IADHLLTTLGDTAATPQAVFVVGSAPDVGD----VAAALEATLEVPVLSA
MAB_4296c|M.abscessus_ATCC_199 VLANLVNPLKGKENAPDGVFLLGLGTDVSD----LAESLGDAIALPVNSP
MLBr_00048|M.leprae_Br4923 SANQHSRHARRGHHHRDETQQANPASATEPMIAPRARTAELRQAPHAAAE
. .
Mb1919|M.bovis_AF2122/97 TMAQVTVARGAALAAAQSTEFTDAQLVADSVS------------------
Rv1887|M.tuberculosis_H37Rv TMAQVTVARGAALAAAQSTEFTDAQLVADSVS------------------
MMAR_2779|M.marinum_M TMAQVTIARGAALAAAQSTDFTDARLIAD-VS------------------
MUL_2968|M.ulcerans_Agy99 TMAQVTIARGAALAAAQSTDFTDARLIAD-VS------------------
MAV_2814|M.avium_104 SMAQVTIARGAALSAARSTEFTDEQLVARRSE------------------
Mflv_3300|M.gilvum_PYR-GCK AEAALALARGAALACAQPGEFAAWEHTTR---------------------
Mvan_3021|M.vanbaalenii_PYR-1 DAAQLALARGAALACASNGDFDVWPGPAS---------------------
MSMEG_3531|M.smegmatis_MC2_155 ADGDLALARGAALVSARRGRF-MFPDKAD---------------------
TH_3639|M.thermoresistible__bu QEGDLALARGAALASARSAAVAYPPARPL---------------------
MAB_4296c|M.abscessus_ATCC_199 DQPELALARGAALASAQEPDFEASTALLGQAYSLEGPTGTGFAHPDAVTE
MLBr_00048|M.leprae_Br4923 PAPTQHLTRPDGLVSHRTALHDSTATSAIGVQTG----------------
::* .* .
Mb1919|M.bovis_AF2122/97 -------------QPTVAPRRSR--HYAGAAAALAAAAVTFVASLSLAVG
Rv1887|M.tuberculosis_H37Rv -------------QPTVAPRRSR--HYAGAAAALAAAAVTFVASLSLAVG
MMAR_2779|M.marinum_M -------------EPAPAPKRSL--HYAGAATTLAAAAVTFVGSLSLAIG
MUL_2968|M.ulcerans_Agy99 -------------EPAPAPKRSL--HYAGAATTLAAAAVTFVGSLSLAIG
MAV_2814|M.avium_104 -------------PVTPAPVRHRRLSYAGAMTALTAGAISFVGSVSLAVG
Mflv_3300|M.gilvum_PYR-GCK --------------QPVTPHATRRRRRRWPQALLAAGAITFVASASAAVA
Mvan_3021|M.vanbaalenii_PYR-1 --------------ERQTRPATTRFARSAPAVLLAAGVVTFVASVSVAVA
MSMEG_3531|M.smegmatis_MC2_155 --------------QQRSRWTSR---QLAPAAMLLVGVVTFVVSLSLAIS
TH_3639|M.thermoresistible__bu --------------RLTR--------VGVLSSVLVAASLTFVVSLSLALT
MAB_4296c|M.abscessus_ATCC_199 SAGEANTELREFEDFDDQPAERKPFLLVGAPLLLVFGICSIALAVSLTVT
MLBr_00048|M.leprae_Br4923 ------------RSTGAKKPSKVVAKRGWRHWVHTVTRINLGLSPDERYE
.: : .
Mb1919|M.bovis_AF2122/97 IQLAPHNDTGT------------AKHGAHKPTPRIAKAVAPAVPPPPTVT
Rv1887|M.tuberculosis_H37Rv IQLAPHNDTGT------------AKHGAHKPTPRIAKAVAPAVPPPPTVT
MMAR_2779|M.marinum_M LQLTPERHHTA------------TGHAGHKPTPEIVEAVAPVVPMPAQPE
MUL_2968|M.ulcerans_Agy99 LQLTPERHHTA------------TGHAGHKPTPEIVEAVAPVVPMPAQPE
MAV_2814|M.avium_104 IHVGPASATAA------------AKHATHPPAPQVAEAVKAVTPLPAAP-
Mflv_3300|M.gilvum_PYR-GCK LQLTPEPIASP------------PRSAAESPVRQPAAPSP---VPP---A
Mvan_3021|M.vanbaalenii_PYR-1 LALTPGQPAPQ------------PRPAAESAAAPPAAAPPRSQVPPPPVA
MSMEG_3531|M.smegmatis_MC2_155 QQMSPREQAFERPTRPVVNTSGTPAAVRQLPPALPAAPPPPPQAPP--AA
TH_3639|M.thermoresistible__bu PQPASEQRATS------------PTAGDARPVAXXXPARP----------
MAB_4296c|M.abscessus_ATCC_199 VRSTVDQGPSSPDRGVVQNPLPAEAPKQAAPPPSPVEAPAPAVSPAPVQQ
MLBr_00048|M.leprae_Br4923 LDLRTRVRRPPRGSYQIGILGLKGGAGKTTVTVTLGSMFARVRNDRILVV
Mb1919|M.bovis_AF2122/97 PPVPARAPRPAAQHEPPARVTSGEALTEPNPPEE----------------
Rv1887|M.tuberculosis_H37Rv PPVPARAPRPAAQHEPPARVTSGEALTEPNPPEE----------------
MMAR_2779|M.marinum_M PSAPHQAPAPGAGQEP-IRLTAGEQITDAAPVE-----------------
MUL_2968|M.ulcerans_Agy99 PSAPHQAPAPGAGQEP-IRLTAGEQITDAAPVE-----------------
MAV_2814|M.avium_104 QTKPQTKPPSGPAPAP-----AGEP---AAPDEQ----------------
Mflv_3300|M.gilvum_PYR-GCK PVAPAPDPAPEP-----VAPAAEDVPVEAPP-------APQELP-----E
Mvan_3021|M.vanbaalenii_PYR-1 AVEPAPVAAVEPAPVAAVEPAPEPVAALVAP-------EPEAPPPVVDEA
MSMEG_3531|M.smegmatis_MC2_155 EVAEAVPPAVDPPLADVAESPVEQALPQLPPQLPLPDAATALPPPVVIPA
TH_3639|M.thermoresistible__bu --ARRPRPGGSPPG------------------------------------
MAB_4296c|M.abscessus_ATCC_199 VVAPAPQHNPAPAPKQVAPAPVQAAPQAPAPAPEAPAPAAPAPVPEEQPA
MLBr_00048|M.leprae_Br4923 DADTSCGNLADRAGRFSEANIADLLADKDVKSYNDIRTHTSVNAVNLEVL
Mb1919|M.bovis_AF2122/97 -----------------------------------------QPNASAPQQ
Rv1887|M.tuberculosis_H37Rv -----------------------------------------QPNASAPQQ
MMAR_2779|M.marinum_M -----------------------------------------QPGGEAPQS
MUL_2968|M.ulcerans_Agy99 -----------------------------------------QPGGEAPQS
MAV_2814|M.avium_104 -----------------------------------------PGIGDDRQM
Mflv_3300|M.gilvum_PYR-GCK QVSPDVL--------------PPATAPVEAVPP------PPPVEP-APAV
Mvan_3021|M.vanbaalenii_PYR-1 QSVPAPL--------------PEQAPVVEAASPDAGLPTAPPVIP-APEV
MSMEG_3531|M.smegmatis_MC2_155 PPTKKPLLSRIRDRLRGEPDVPEQMVIGEPPPPAEITPIPPPGAPPAPPV
TH_3639|M.thermoresistible__bu --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199 PVAPPPAVVPVPIPLFPPVWEPPRRQENPWWPDRDRPRYTPPAQTQQPPI
MLBr_00048|M.leprae_Br4923 PAAEYSTAQHALSGEDWNFAAATVSKYYNVMLADCGVGLFDPVTRGVLST
Mb1919|M.bovis_AF2122/97 DRNDSQP-ITRVLEHIPGAYG----DSAPPAE------------------
Rv1887|M.tuberculosis_H37Rv DRNDSQP-ITRVLEHIPGAYG----DSAPPAE------------------
MMAR_2779|M.marinum_M EPADGSPMLTRVLTHIPGSYGE--EEGSRPPE------------------
MUL_2968|M.ulcerans_Agy99 EPADGSPMLTRVLTHIPGSYGE--EEGSRPPE------------------
MAV_2814|M.avium_104 ESGNRQPYLTRVLEHIPGDTGEPAADSAPHPTLDPQP-------------
Mflv_3300|M.gilvum_PYR-GCK IPAPVPAERPGILDRIRDRLSRVG--DP-VVEMPPP------PVPGAPV-
Mvan_3021|M.vanbaalenii_PYR-1 VP-PVPQERPGILQRIRDRLSNVGPDDPQQAAVPPP------PAP-----
MSMEG_3531|M.smegmatis_MC2_155 DDAPAPEAPP---EPPPAPEAPPAADPPPPADVPPPDPPPAEPAPVEPEP
TH_3639|M.thermoresistible__bu --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199 ISIPGLPPIGGGDSDRGSHGGSRGGSGRGGWGDDGDSRGGSDSGSRGGWG
MLBr_00048|M.leprae_Br4923 ASGVVIVTSTSVDAARQAAIALDWLRHNGYQDLLSRACVVINHVMPKEPN
Mb1919|M.bovis_AF2122/97 --------------------------------------------------
Rv1887|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2779|M.marinum_M --------------------------------------------------
MUL_2968|M.ulcerans_Agy99 --------------------------------------------------
MAV_2814|M.avium_104 --------------------------------------------------
Mflv_3300|M.gilvum_PYR-GCK APVPPPLP------------------------------------------
Mvan_3021|M.vanbaalenii_PYR-1 ---APPLP------------------------------------------
MSMEG_3531|M.smegmatis_MC2_155 APEAPPAP------------------------------------------
TH_3639|M.thermoresistible__bu --------------------------------------------------
MAB_4296c|M.abscessus_ATCC_199 DNGGSRGGWGDSGSSRGGSDSGSRGGWGGNSGSHGGGSGGGSNSGFPWPF
MLBr_00048|M.leprae_Br4923 IASKDLVQQFEQQIQPGRVVVLPWDKHIAAGTEIRLDRLDPLYRRRILEL
Mb1919|M.bovis_AF2122/97 --------------
Rv1887|M.tuberculosis_H37Rv --------------
MMAR_2779|M.marinum_M --------------
MUL_2968|M.ulcerans_Agy99 --------------
MAV_2814|M.avium_104 --------------
Mflv_3300|M.gilvum_PYR-GCK --------------
Mvan_3021|M.vanbaalenii_PYR-1 --------------
MSMEG_3531|M.smegmatis_MC2_155 --------------
TH_3639|M.thermoresistible__bu --------------
MAB_4296c|M.abscessus_ATCC_199 GGR-----------
MLBr_00048|M.leprae_Br4923 AAALSDDFERAGRH