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APLAIAGLSVVGLVMAAPAAADPVPDPAPPGPAVAAPGQPIVEPAEGSALPPAPPPVGPPPVPEMANPMY GSGQSGSGPLGSLRDLWHQARDPGGMQLAPTGGVAPPPGAGAPPPLPPGYVSINAPGSETPVTEDPAGNA GGPPLPPGYYPLDGPPPPGYEYNSPVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3441 | - | - | 100% (168) | hypothetical protein MSMEG_3441 |
| M. smegmatis MC2 155 | MSMEG_5268 | - | 6e-12 | 36.97% (119) | hypothetical protein MSMEG_5268 |
| M. smegmatis MC2 155 | MSMEG_5700 | - | 1e-10 | 32.95% (176) | secreted protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2590 | - | 4e-11 | 57.14% (70) | hypothetical protein Mb2590 |
| M. gilvum PYR-GCK | Mflv_0374 | - | 2e-14 | 33.71% (178) | hypothetical protein Mflv_0374 |
| M. tuberculosis H37Rv | Rv2560 | - | 5e-11 | 57.14% (70) | hypothetical protein Rv2560 |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 7e-07 | 41.10% (73) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_2500 | - | 3e-40 | 51.12% (178) | hypothetical protein MAB_2500 |
| M. marinum M | MMAR_2166 | - | 1e-10 | 36.09% (133) | proline and glycine rich transmembrane protein |
| M. avium 104 | MAV_4986 | - | 3e-11 | 33.53% (173) | ErfK/YbiS/YcfS/YnhG family protein |
| M. thermoresistible (build 8) | TH_3066 | - | 9e-07 | 33.82% (136) | PUTATIVE virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_1750 | - | 3e-10 | 39.09% (110) | proline and glycine rich transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_0309 | - | 9e-16 | 34.68% (173) | hypothetical protein Mvan_0309 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2590|M.bovis_AF2122/97 MSQPPEHPGNPADPQGGNQGAGSYPPP----------------------G
Rv2560|M.tuberculosis_H37Rv MSQPPEHPGNPADPQGGNQGAGSYPPP----------------------G
MMAR_2166|M.marinum_M MSQPPENPGNQADPQGGDQSTPGYPPPPNYGTPPPPPPPGYGAPPAGPPG
MUL_1750|M.ulcerans_Agy99 MSQPPENPGNQADPQDGDQSTPGYPPPPNYGTPPPPPPPGYGAPPAGPPG
MAV_4986|M.avium_104 --------------------------------------------------
TH_3066|M.thermoresistible__bu LEESDRLRNGLKGIIILLLVIGVGQSFASVPMLFATPTYYAQFYDTGGIK
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2590|M.bovis_AF2122/97 YGAPPPPP--------------------GYGPPPGTYLPPGYN-APPPPP
Rv2560|M.tuberculosis_H37Rv YGAPPPPP--------------------GYGPPPGTYLPPGYN-APPPPP
MMAR_2166|M.marinum_M YGAPPPPPGYGTPPPPPGYGTPPPPPPPGYGQAPGGYAPPGYNPPPPPPP
MUL_1750|M.ulcerans_Agy99 YGAPPPPP---------GYGTPPPPPPPGYGQAPGGYAPPGYNPPPPPPP
MAV_4986|M.avium_104 --------------------------------------------------
TH_3066|M.thermoresistible__bu AGDKVRIAGVDVGLVRSATINGDKVRIGFTLGGVQIGTDSRASIRTDTIL
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2500|M.abscessus_ATCC_1997 -------------------------------------------------M
Mflv_0374|M.gilvum_PYR-GCK -------------------------------------------------M
Mvan_0309|M.vanbaalenii_PYR-1 -------------------------------------------------M
Mb2590|M.bovis_AF2122/97 GYGPPPG--PPPPGYPTHLQSSGFSVGDAISWSWNRFTQNAVTLVVPVLA
Rv2560|M.tuberculosis_H37Rv GYGPPPG--PPPPGYPTHLQSSGFSVGDAISWSWNRFTQNAVTLVVPVLA
MMAR_2166|M.marinum_M GYGPPPAGYPAQPGFGGPAKPP-FSVGEAISWAWNRFTQNAMALVVPIVI
MUL_1750|M.ulcerans_Agy99 GYGPPPAGYSTQPGFGGPAKPP-FSVGEAISWAWNRFTQNAMALVVPIVI
MAV_4986|M.avium_104 -----------------------------MSGWTRGTLFAALNAAVVSVV
TH_3066|M.thermoresistible__bu GRKNMEIEPRGTEPLRTNGVLPIGQTTTPYQIYDAFFDVTKAATEWDTRT
MLBr_02395|M.leprae_Br4923 ----------------------------------------MTDQPPPSGS
MSMEG_3441|M.smegmatis_MC2_155 -MAPLAIAGLSVVG--LVMAAP----AAADPVPDPAPPGP-AVAAPGQP-
MAB_2500|M.abscessus_ATCC_1997 DVAKLFVAGVIVAG--AALSLS----APAG--ADPAEPGPGPSPAPSAP-
Mflv_0374|M.gilvum_PYR-GCK HIVKVAALNALLSC--AALAAATHAGAQPAVPFDP--PPPPPAAAPAQPQ
Mvan_0309|M.vanbaalenii_PYR-1 QVVKIAALNALLGG--AALAAATQAGAQPA-PVDPALPPAPPVVAAPAPG
Mb2590|M.bovis_AF2122/97 YAVALAAVIGATAG--LVVALSDRATTAYTNTSGVSSESVDITMTPAAGI
Rv2560|M.tuberculosis_H37Rv YAVALAAVIGATAG--LVVALSDRATTAYTNTSGVSSESVDITMTPAAGI
MMAR_2166|M.marinum_M YGLILSAVGGVMVG--LFFAFSDRTSTTYTDAYGNTSETVNMTMSPLASI
MUL_1750|M.ulcerans_Agy99 YGLILSAVGGVMVG--LFFAFSDRTSTTYTDAYGNTSETVNMTMSPLASI
MAV_4986|M.avium_104 GLALVLSAGPALADPDPAPADPGAVAAPPGPPAPPDPLAPPPPPDPLAPP
TH_3066|M.thermoresistible__bu VRESLNVLSETIDQTYPHLSAALDGVARFSDTIGKRDEQITQLLANANKI
MLBr_02395|M.leprae_Br4923 NPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVGGSYPPPPPPGGSY
: . :
MSMEG_3441|M.smegmatis_MC2_155 ----------------IVEPAEG--SALPPAPPPVGP-------------
MAB_2500|M.abscessus_ATCC_1997 ----------------QAAAPGT--EALGPPPPPALQ-------------
Mflv_0374|M.gilvum_PYR-GCK TPVFQYIPIAEGAAPGSPAAPAG--PVAPPAPPPAGA-------------
Mvan_0309|M.vanbaalenii_PYR-1 APVPG-VPAPGSHSVTVTPLDAG--SIPPPAPPPVGA-------------
Mb2590|M.bovis_AF2122/97 VMFLGYIALFALVLYMHAGILTGCLDIADGKPVTIAT-------------
Rv2560|M.tuberculosis_H37Rv VMFLGYIALFALVLYMHAGILTGCLDIADGKPVTIAT-------------
MMAR_2166|M.marinum_M VMFIGYLAVFAVVLFMHAGITTGCLDIADGKPVTIGS-------------
MUL_1750|M.ulcerans_Agy99 VMFIGYLAVFAVVLFMHAGITTGCLDIADGKPVTIGS-------------
MAV_4986|M.avium_104 PPAAPPAPWLPPAAQPAAAPAAGQDPTPFTGTPPFGP-------------
TH_3066|M.thermoresistible__bu AEVLGDRGGQINALLVNAQTLLGAINERTQAVDLLLQRISQVSTQVRGFI
MLBr_02395|M.leprae_Br4923 PP-----PPPPGGSYPPPPPSTGAYAPPPPGPAIRSLP----------KE
MSMEG_3441|M.smegmatis_MC2_155 ---PPVPEMANPMYGSGQ----SGSGPLGSLRDLWHQARDPGGMQLAPTG
MAB_2500|M.abscessus_ATCC_1997 ---PSVPEVTNPTYGSG-----SG-GPLGTIRDLWHQAHD--GPLDTPEG
Mflv_0374|M.gilvum_PYR-GCK ---PFIPPVPNANFGNT--------GQFDFLRDLWNMRNS------PEFM
Mvan_0309|M.vanbaalenii_PYR-1 ---PVIPAVPNANFGNT--------GQLDFLRELWNMRNS------AEFF
Mb2590|M.bovis_AF2122/97 ---FFRPRNLGLVLVTG-----LLIVALTFIGGLLCVIPGLIFGFVAQFA
Rv2560|M.tuberculosis_H37Rv ---FFRPRNLGLVLVTG-----LLIVAVTFIGGLLCVIPGLIFGFVAQFA
MMAR_2166|M.marinum_M ---FFKPRNLGMVILTG-----LLVIVLTAIGSVLCIVPGLIFGFLAQFA
MUL_1750|M.ulcerans_Agy99 ---FFKPRNLGMVILTG-----LLVIVLTAIGSVLCIVPGLIFGFLAQFA
MAV_4986|M.avium_104 ---PTFVPKTGSTVGVAQPIIINFPGRVDDAGAAISAVHVSSVPPVPGKF
TH_3066|M.thermoresistible__bu DDNPNLNTVLEQLRQVSDILVERRYDLVDVLSSLSKFTASLAEGLASGPY
MLBr_02395|M.leprae_Br4923 AYTFWVTRVLAYVIDNIPATVLLGIGMLIQTLTKQEACVTDITQYNVNQY
.
MSMEG_3441|M.smegmatis_MC2_155 GVAPPP-GAGAPPPLPPGYVSINAPGSETP-----------VTEDP--AG
MAB_2500|M.abscessus_ATCC_1997 VAGRPA-NAGPAPQLPPGYISTNAPESSNPG----------RIRDPYAAP
Mflv_0374|M.gilvum_PYR-GCK QSVGPG-QMDPSTWVPPTPYGDPAAAPAPP--------------------
Mvan_0309|M.vanbaalenii_PYR-1 QSVGPG-SLDPATWQPPTPYGTPPPPPAA---------------------
Mb2590|M.bovis_AF2122/97 VAFAVDRSTSPIDSVKASIETVGSNIGGSVLSWLAQLTAVLVGELLCFVG
Rv2560|M.tuberculosis_H37Rv VAFAVDRSTSPIDSVKASIETVGSNIGGSVLSWLAQLTAVLVGELLCFVG
MMAR_2166|M.marinum_M IIAAVDRSLSPIDSIKSSFATVRAELGNTALSWLVQYAVVLAGELLCFVG
MUL_1750|M.ulcerans_Agy99 IIAAVDRSLSPIDSIKSSCATVRAELGNTALSWLVQYAVVLAGELLCFVG
MAV_4986|M.avium_104 YWMTPTQLRWRPLSFWPAHTAVTVDAGGTVTNFQTGDTLVATADDATHQL
TH_3066|M.thermoresistible__bu FKVMLVNLVPYQILQPFVDAAFKERGIDPENFWRGAGLPEFQWPDPNAER
MLBr_02395|M.leprae_Br4923 CATQPTGIGMLAFWFAWLMATAYLVWNYGYRQGATGSSIGKTVMKFKVIS
MSMEG_3441|M.smegmatis_MC2_155 NAGGP-------PLPPGYYPLDG-------------PPPPGYEYNSPVP-
MAB_2500|M.abscessus_ATCC_1997 EPSGP-------PLPPGYHSLNG-------------PPPPGYEPTGPAPA
Mflv_0374|M.gilvum_PYR-GCK AAGSP-------PVPASAPPPIW-------------PPVP---VPAPVP-
Mvan_0309|M.vanbaalenii_PYR-1 APGSP-------PPPASAPPPVW-------------PPVP---VPAQVP-
Mb2590|M.bovis_AF2122/97 MLIGI-------PVAALIHVYTYRKLSGGQVVEAVRPAPPVGWPPGP---
Rv2560|M.tuberculosis_H37Rv MLIGI-------PVAALIHVYTYRKLSGGQVVEAVRPAPPVGWPPGP---
MMAR_2166|M.marinum_M MLVGV-------PVASLIQTYTWRKLSGGQVVELSQPGPPAGLPPGPPPG
MUL_1750|M.ulcerans_Agy99 MLVGV-------PVASLIQTYTWRKLSGGQVVELSQPGPPAGLPPGPPPG
MAV_4986|M.avium_104 TVTRNGTVEKTFPMSMGMTAGNHQTPNGTYYVQDKKASVVMDSSTYGVPV
TH_3066|M.thermoresistible__bu HANGAPP---AAPRPIEGTPEHPGPAVPPGHPCSYTPAANAAPRPGDPLP
MLBr_02395|M.leprae_Br4923 EATGQ-------PIGFGMSVVRQLAHFVDAVICCIGFLFPLWDSKRQTLA
*
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2500|M.abscessus_ATCC_1997 AATP----------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2590|M.bovis_AF2122/97 -----QLA------------------------------------------
Rv2560|M.tuberculosis_H37Rv -----QLA------------------------------------------
MMAR_2166|M.marinum_M APPGPQFG------------------------------------------
MUL_1750|M.ulcerans_Agy99 APPGPQFG------------------------------------------
MAV_4986|M.avium_104 NSTYGYKVTVEDAVRFDNVGDYVHSAPWSVDDQGKRDVSHGCINISPANA
TH_3066|M.thermoresistible__bu CADAGVGPFGDNPYGPNYAPPNVVGEPHNPDAQPSPGLPAAAVPGQVSPN
MLBr_02395|M.leprae_Br4923 DKIMTTVCLPI---------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 ----------------------------------
MAB_2500|M.abscessus_ATCC_1997 ----------------------------------
Mflv_0374|M.gilvum_PYR-GCK ----------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 ----------------------------------
Mb2590|M.bovis_AF2122/97 ----------------------------------
Rv2560|M.tuberculosis_H37Rv ----------------------------------
MMAR_2166|M.marinum_M ----------------------------------
MUL_1750|M.ulcerans_Agy99 ----------------------------------
MAV_4986|M.avium_104 KWFFDNFGPGDPIIVKNSSGGDYKKNDGSADWMN
TH_3066|M.thermoresistible__bu VPGAPGPGVAPGPPGXXXARRPARSSPGRSPAP-
MLBr_02395|M.leprae_Br4923 ----------------------------------