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MDVAKLFVAGVIVAGAALSLSAPAGADPAEPGPGPSPAPSAPQAAAPGTEALGPPPPPALQPSVPEVTNP TYGSGSGGPLGTIRDLWHQAHDGPLDTPEGVAGRPANAGPAPQLPPGYISTNAPESSNPGRIRDPYAAPE PSGPPLPPGYHSLNGPPPPGYEPTGPAPAAATP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2500 | - | - | 100% (173) | hypothetical protein MAB_2500 |
| M. abscessus ATCC 19977 | MAB_3131c | - | 2e-08 | 30.39% (181) | translation initiation factor IF-2 (InfB) |
| M. abscessus ATCC 19977 | MAB_0630 | - | 4e-08 | 28.05% (164) | hypothetical protein MAB_0630 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1188c | - | 6e-08 | 30.81% (211) | hypothetical protein Mb1188c |
| M. gilvum PYR-GCK | Mflv_0374 | - | 7e-12 | 30.95% (168) | hypothetical protein Mflv_0374 |
| M. tuberculosis H37Rv | Rv1157c | - | 6e-08 | 30.81% (211) | hypothetical protein Rv1157c |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 1e-05 | 37.80% (82) | proline rich antigenic protein |
| M. marinum M | MMAR_5451 | - | 1e-09 | 29.55% (176) | hypothetical protein MMAR_5451 |
| M. avium 104 | MAV_5013 | - | 1e-08 | 30.00% (170) | mce-family protein mce1c |
| M. smegmatis MC2 155 | MSMEG_3441 | - | 4e-40 | 51.12% (178) | hypothetical protein MSMEG_3441 |
| M. thermoresistible (build 8) | TH_0991 | ftsH | 1e-07 | 26.45% (155) | MEMBRANE-BOUND PROTEASE FTSH (CELL DIVISION PROTEIN) |
| M. ulcerans Agy99 | MUL_1004 | - | 8e-09 | 27.35% (245) | hypothetical protein MUL_1004 |
| M. vanbaalenii PYR-1 | Mvan_0309 | - | 2e-14 | 31.36% (169) | hypothetical protein Mvan_0309 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 -----------------------------------------MRRLTNTEH
Rv1157c|M.tuberculosis_H37Rv -----------------------------------------MRRLTNTEH
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5451|M.marinum_M MPADYDELFQPAEGSGPPDDETGQTFFDPGTAYPPPVKPNGDGHSAPKDW
MAV_5013|M.avium_104 --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_0991|M.thermoresistible__bu ---------------------------MNRKTVIRTLTIVAVVLLLGWSF
MAB_2500|M.abscessus_ATCC_1997 ---------MDVAKLFVAGVIVAGAALSLSAPAG--ADPAEPGPGPSPAP
MSMEG_3441|M.smegmatis_MC2_155 -----------MAPLAIAGLSVVGLVMAAPAAADPVPDPAPPGP-AVAAP
Mflv_0374|M.gilvum_PYR-GCK ---------MHIVKVAALNALLSCAALAAATHAGAQPAVPFDP--PPPPP
Mvan_0309|M.vanbaalenii_PYR-1 ---------MQVVKIAALNALLGGAALAAATQAGAQPA-PVDPALPPAPP
Mb1188c|M.bovis_AF2122/97 RENTTVASTWSVCKGLAAVVITSAAAFALCPNAAADPATPQPNPTQQLPG
Rv1157c|M.tuberculosis_H37Rv RENTTVASTWSVCKGLAAVVITSAAAFALCPNAAADPATPQPNPTQQLPG
MUL_1004|M.ulcerans_Agy99 -----MASTWSLSKGLAAVVVTSAAAFGLCPAAAADPAAPQPNPNPQLPG
MMAR_5451|M.marinum_M SRAFPPAEDESPSDSAEPAAGPAKSPLPPMPIGGPAPTPPEPPPAPPELP
MAV_5013|M.avium_104 ---MRTLEPPNRVRIGLMGIVVTVLVIGVGQSFTSVPMLFAKPSYYGQFT
MLBr_02395|M.leprae_Br4923 ---MTDQPPPSGSNPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVG
TH_0991|M.thermoresistible__bu FYFGDDTREYKPVDTSVALAQIQADNVDSAQIDDREQQVRLDLKNANSDT
MAB_2500|M.abscessus_ATCC_1997 SAPQAAAPGTEALGPPPPPALQPSVPE----VTNPTYGSG-SG-------
MSMEG_3441|M.smegmatis_MC2_155 GQPIVEPAEGSALPPAPPPVGPPPVPE----MANPMYGSGQSGS------
Mflv_0374|M.gilvum_PYR-GCK AAAPAQPQTPVFQYIPIAEGAAPGSPA----APAGPVAPPAPPP------
Mvan_0309|M.vanbaalenii_PYR-1 VVAAPAPGAPVPG-VPAPGSHSVTVTP----LDAGSIPPPAPPP------
Mb1188c|M.bovis_AF2122/97 LPALAQLSPIIQQAAMNPAQATQLLMA----AASAFAGNPAVPTESKNVA
Rv1157c|M.tuberculosis_H37Rv LPALAQLSPIIQQAAMNPAQATQLLMA----AASAFAGNPAVPTESKNVA
MUL_1004|M.ulcerans_Agy99 LPALAQLSPIIQQAAGNPEQATQLLMA----AAQAFAHNPAAPTESRNVA
MMAR_5451|M.marinum_M -PAPPEPPPARPEAPPQAPTAEAEPPD----EAIPVSGPPPGGKSPLPPM
MAV_5013|M.avium_104 DSGGINTGDKVRIAGMDVGKVEGLKIDGDHIVVKFSIGTNTIGTESRLAI
MLBr_02395|M.leprae_Br4923 GSYPPPPPPGGSYPPPPPPGGSYPPPP----PSTGAYAPPPPGPAIR---
TH_0991|M.thermoresistible__bu GDSDKIIAKYPTGYAVPLFDALQDKNAKVNTVVNQGSVLGTLLIYMLPLL
MAB_2500|M.abscessus_ATCC_1997 ---------------------------------GPLGTIRDLWHQAHD--
MSMEG_3441|M.smegmatis_MC2_155 ---------------------------------GPLGSLRDLWHQARDPG
Mflv_0374|M.gilvum_PYR-GCK -------------------------------AGAPFIPPVPNANFG--NT
Mvan_0309|M.vanbaalenii_PYR-1 -------------------------------VGAPVIPAVPNANFG--NT
Mb1188c|M.bovis_AF2122/97 SSVNQFVAEPTNPD--SAALGVPAPHG----VALPEAIPVPHVPPLGAEP
Rv1157c|M.tuberculosis_H37Rv SSVNQFVAEPTNPD--SAALGVPAPHG----VALPEAIPVPHVPPLGAEP
MUL_1004|M.ulcerans_Agy99 SSVNQFVQEPVNPAPGSPPLGVPAPAAAPVEVAPPASAPVPHVPAPGAEP
MMAR_5451|M.marinum_M PIGGPPPASPEPPAAPPEPTAPAEPPQPPEAAAQPPQAVEEQAHATAEPP
MAV_5013|M.avium_104 KTDTILGKKILDVEARGSQQLRPGSTLPLGQSTTPYQIYDAFFDVTKAAQ
MLBr_02395|M.leprae_Br4923 ----------------------SLPKEAYTFWVTRVLAYVIDNIPATVLL
TH_0991|M.thermoresistible__bu LLVALFVFFMRMQSGGRMGFGFGKSKAKQLSKDMPKTTFADVAGVDEAVE
MAB_2500|M.abscessus_ATCC_1997 GPLDTPEGVAGRPANAGPAPQLP-----------PGYISTNAPES-----
MSMEG_3441|M.smegmatis_MC2_155 GMQLAPTGGVAPPPGAGAPPPLP-----------PGYVSINAPGS-----
Mflv_0374|M.gilvum_PYR-GCK GQFDFLRDLWNMRNSPEFMQSVG-----------PGQMDPSTWVP-----
Mvan_0309|M.vanbaalenii_PYR-1 GQLDFLRELWNMRNSAEFFQSVG-----------PGSLDPATWQP-----
Mb1188c|M.bovis_AF2122/97 GVQAHLPTGIDPSHAAGPAPAVA-----------PTVTPPVAAPP--ASA
Rv1157c|M.tuberculosis_H37Rv GVQAHLPTGIDPSHAAGPAPAVA-----------PTVTPPVAAPP--ASA
MUL_1004|M.ulcerans_Agy99 GTLAHLPAGIDPAHAAGPAPVAA-----------PAGAPPASAPAPAAAA
MMAR_5451|M.marinum_M AAPNPPRPPMPIGGPPPTPPAAPEPQQDIAEEPAPAAAEAPAAPPKSPLP
MAV_5013|M.avium_104 GWDIETVKQSLHVLSQTIDQTYP--------HLSPALDGVAKFSDTIGKR
MLBr_02395|M.leprae_Br4923 GIGMLIQTLTKQEACVTDITQYN------------VNQYCATQPTGIGML
TH_0991|M.thermoresistible__bu ELYEIKDFLQNPSRYQALGAKIPKG---VLLYGPPGTGKTLLARAVAGEA
MAB_2500|M.abscessus_ATCC_1997 --------SNPGRIRDPYAAPEPSG-------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------ETP-VTEDP--AGNAGG-------------------------
Mflv_0374|M.gilvum_PYR-GCK --------PTPYGDPAAAPAPPAAG-------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------PTPYGTPPPPPAA-APG-------------------------
Mb1188c|M.bovis_AF2122/97 PAPAP-DAAQPVAVPGPPPAPPAPR-------------------------
Rv1157c|M.tuberculosis_H37Rv PAPAP-DAAQPVAVPGPPPAPPAPR-------------------------
MUL_1004|M.ulcerans_Agy99 PASAPGTAPAPAAAPGPAPAAPAPAPAAAAPAPAPAPAAPPAAPVAAPVA
MMAR_5451|M.marinum_M PMPVSGPPPEPPELPPAPPEPTASAE----------PPQPPQSVEEQAHA
MAV_5013|M.avium_104 DEQVKHLLAQANQVASVLGDRSDQIDRLLVN-------------------
MLBr_02395|M.leprae_Br4923 AFWFAWLMATAYLVWNYGYRQGATG-------------------------
TH_0991|M.thermoresistible__bu GVPFFTISGSDFVEMFVGVGASRVRDLFEQAK----------------QN
MAB_2500|M.abscessus_ATCC_1997 ------------PPLPPGYHSLNGPPPPGYEP------------------
MSMEG_3441|M.smegmatis_MC2_155 ------------PPLPPGYYPLDGPPPPGYEY------------------
Mflv_0374|M.gilvum_PYR-GCK ------------SPPVPASAPPPIWPPVPVP-------------------
Mvan_0309|M.vanbaalenii_PYR-1 ------------SPPPPASAPPPVWPPVPVP-------------------
Mb1188c|M.bovis_AF2122/97 ----------AAAPAPASAAPAPAAAPAPAS--GFGADAPPTQDFMYPSI
Rv1157c|M.tuberculosis_H37Rv ----------AAAPAPASAAPAPAAAPAPAS--GFGADAPPTQDFMYPSI
MUL_1004|M.ulcerans_Agy99 APAPVPAPAPAAAPAPEAAAPAPAPAPAPAAAPGFGPDAPPTQDFMYPSI
MMAR_5451|M.marinum_M TAEPPAAPKPTRPPMPIGGPPPTPEPQQGAPQPHQDIAEEPNPAAAEAPA
MAV_5013|M.avium_104 ---TKTLLAAFNERGQAINALLGNIAAFSEQVKGLINDNPNLNHVLEQLR
MLBr_02395|M.leprae_Br4923 ------------SSIGKTVMKFKVISEATGQPIGFG--------------
TH_0991|M.thermoresistible__bu SPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRQGVIL
MAB_2500|M.abscessus_ATCC_1997 --------------------TGPAPAAATP--------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------NSPVP-------------------------
Mflv_0374|M.gilvum_PYR-GCK ---------------------APVP-------------------------
Mvan_0309|M.vanbaalenii_PYR-1 ---------------------AQVP-------------------------
Mb1188c|M.bovis_AF2122/97 GPNCVADGSNSIATALSVAGPAKIPLPGPGPGQTAYVFTAVGTPGPADVQ
Rv1157c|M.tuberculosis_H37Rv GPNCVADGSNSIATALSVAGPAKIPLPGPGPGQTAYVFTAVGTPGPADVQ
MUL_1004|M.ulcerans_Agy99 GTNCLADGSNIIATALSVAGPATIPTPGPGPGQTAYVFTAVGTPGPAEVQ
MMAR_5451|M.marinum_M APPKSPRPPMPVNGPAPTRPEPPLPPGPPRRRAQPPTAPPNQPGQPKPIS
MAV_5013|M.avium_104 TVSDILVQRKDDLANGLTEVGKFLPSLNEAIASGPFFKVVLHNLALYQIS
MLBr_02395|M.leprae_Br4923 -----------------MSVVRQLAHFVDAVICCIGFLFPLWDSKRQTLA
TH_0991|M.thermoresistible__bu IAATNRPDILDPALLRPGRFDRQIPVTNPDLAGRKAVLRVHAQGKPLAPD
.
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 RLP--------LNVTWVNLTTGKSGSATLRPRSDINPDGPTTLTVIADTG
Rv1157c|M.tuberculosis_H37Rv RLP--------LNVTWVNLTTGKSGSATLRPRSDINPDGPTTLTVIADTG
MUL_1004|M.ulcerans_Agy99 RLP--------LNVTWVNLTTGKSGSVTLKPRSDINPEGPTTLTGIADTG
MMAR_5451|M.marinum_M GHPPPPPRPAAFAPPARGATPNRHESAEPPPPRRVRIGGPPQPPGPPEAE
MAV_5013|M.avium_104 QPWVDAAFKKRGIDPEDFWRSAGLPAYRFPDPNGTRFPNGAPPPAPPVLE
MLBr_02395|M.leprae_Br4923 DKIMTTVCLPI---------------------------------------
TH_0991|M.thermoresistible__bu VDLDGLAKRTVGMSGADLANVINEAALLTARENGTMITGPALEEAVDRVV
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 SGSIMSTIFGQVTTKDRQCQFMPTIGSTVVP-------------------
Rv1157c|M.tuberculosis_H37Rv SGSIMSTIFGQVTTKDRQCQFMPTIGSTVVP-------------------
MUL_1004|M.ulcerans_Agy99 SGSIMSTIFGQVTTKERQCQFMPTIGSTVVP-------------------
MMAR_5451|M.marinum_M SEAPRHSRHARRTHRYRPEPETDDLEATAVRPLPTREPMRRNGPAADESS
MAV_5013|M.avium_104 GTPDHPGPAVPPGSPCSYTPAADGLPRPDNPLPCAGAVTGPFGGPGFPAP
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_0991|M.thermoresistible__bu GGPRRKSRLISELEKKITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTG
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 --------------------------------------------------
Rv1157c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5451|M.marinum_M TASFAWLQQSQPTLDRPSGPMPAAPGAPVESAPGRADGRRARRRAESRTS
MAV_5013|M.avium_104 VDVMTSPPNPAGLPPTPGIPIAGRPGDAPPDVPGTPVPLPTQAPPGARTE
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_0991|M.thermoresistible__bu GHAVAVPEDDKGLMTRSEMIARLVFAMGGRAAEELVFREPTTGAVSDIEQ
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 --------------------------------------------------
Rv1157c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5451|M.marinum_M AASTPSPLVPTRAQPPGPTRAQPPRTAAPAQPATEPLPDAGAPAEQSKKP
MAV_5013|M.avium_104 NLAPAGPVPPPSTFAPGLPPGPPAPPGPGNQLPAPFINPGGTGGSGAAGG
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_0991|M.thermoresistible__bu ATKIARAMVTEYGMSSKLGAVRYGTEHGDPFLGRTMGTHADYSHEVARDI
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 --------------------------------------------------
Rv1157c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5451|M.marinum_M NKPVPQRGWRRWVYAVTRINFGLSPDEKYELDLRTRIGRKPRGSYQIAIL
MAV_5013|M.avium_104 GSQN----------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_0991|M.thermoresistible__bu DDEIRKLIEAAHTEAWEILTEYRDVLDVLAGELLEKETLHRRELEVILAD
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 --------------------------------------------------
Rv1157c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5451|M.marinum_M GLKGGAGKTTTTVTLGTTLTHVRGDRILVLDADPGAGNLAERSGRSSPSS
MAV_5013|M.avium_104 --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_0991|M.thermoresistible__bu VKKRPRLTMFDDFGGRTPSDKPPIKTPGELAMERGEPWPKPEPEPAFKVA
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 --------------------------------------------------
Rv1157c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5451|M.marinum_M IADLLADPRLSHYNDVRAHTSVNAANLEILPTAEYTSAQRGLSGEDLRSA
MAV_5013|M.avium_104 --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_0991|M.thermoresistible__bu IAEATRAAEAASGQNGQNGHNGTPGPTGPNGTPSAPAQQPAPVVPDYGAP
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 --------------------------------------------------
Rv1157c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5451|M.marinum_M VDTVSKFYNLVLADCGAGLFDPVTLGVLDTASAIVILTNVSIDSARQAAI
MAV_5013|M.avium_104 --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_0991|M.thermoresistible__bu AGWHAPGWPPQPTPQQQPPPYQQPHGQWYPPQQQPGWQQQQQPYPSQYSP
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 --------------------------------------------------
Rv1157c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MMAR_5451|M.marinum_M ALDWLRKHGYQDLASRACVAINHVAVGETNVSEQQLVRDFEQQLQPGRVV
MAV_5013|M.avium_104 --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_0991|M.thermoresistible__bu YQPYPQPSPPAPPGGAAPNDQESGQDPNRTNPPGQG--------------
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------
Mb1188c|M.bovis_AF2122/97 --------------------------------------------
Rv1157c|M.tuberculosis_H37Rv --------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------
MMAR_5451|M.marinum_M VLPWDRHIAAGTEIHLDQLGPVYRRRVLELAAALSDDFERAGRR
MAV_5013|M.avium_104 --------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------
TH_0991|M.thermoresistible__bu --------------------------------------------