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QVVKIAALNALLGGAALAAATQAGAQPAPVDPALPPAPPVVAAPAPGAPVPGVPAPGSHSVTVTPLDAGS IPPPAPPPVGAPVIPAVPNANFGNTGQLDFLRELWNMRNSAEFFQSVGPGSLDPATWQPPTPYGTPPPPP AAAPGSPPPPASAPPPVWPPVPVPAQVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0309 | - | - | 100% (169) | hypothetical protein Mvan_0309 |
| M. vanbaalenii PYR-1 | Mvan_5049 | - | 1e-13 | 35.67% (157) | FHA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_0626 | - | 7e-13 | 38.51% (161) | hypothetical protein Mvan_0626 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1891 | apa | 3e-10 | 33.57% (140) | hypothetical protein Mb1891 |
| M. gilvum PYR-GCK | Mflv_0374 | - | 5e-60 | 66.48% (179) | hypothetical protein Mflv_0374 |
| M. tuberculosis H37Rv | Rv1860 | apa | 6e-11 | 34.29% (140) | hypothetical protein Rv1860 |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 1e-07 | 31.01% (129) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_2500 | - | 1e-14 | 31.36% (169) | hypothetical protein MAB_2500 |
| M. marinum M | MMAR_4294 | - | 1e-14 | 38.06% (155) | hypothetical protein MMAR_4294 |
| M. avium 104 | MAV_3468 | secD | 8e-12 | 34.29% (140) | preprotein translocase subunit SecD |
| M. smegmatis MC2 155 | MSMEG_3441 | - | 9e-16 | 34.68% (173) | hypothetical protein MSMEG_3441 |
| M. thermoresistible (build 8) | TH_3554 | - | 6e-06 | 41.38% (58) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1004 | - | 3e-14 | 38.06% (155) | hypothetical protein MUL_1004 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mb1891|M.bovis_AF2122/97 --------------------------------------------------
Rv1860|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4294|M.marinum_M --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3468|M.avium_104 MASSSVPVHPARYLSVFLLLLVGVYLLVFLTGDKRAAPKLGIDLQGGTRV
TH_3554|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 ------------------------------MQVVKIAALN----------
Mflv_0374|M.gilvum_PYR-GCK ------------------------------MHIVKVAALN----------
Mb1891|M.bovis_AF2122/97 ----------------MHQVDPNLTRRKGRLAALAIAAMAS---------
Rv1860|M.tuberculosis_H37Rv ----------------MHQVDPNLTRRKGRLAALAIAAMAS---------
MMAR_4294|M.marinum_M -----------------MASTWSLSKGLAAVVVTSAAAFG----------
MUL_1004|M.ulcerans_Agy99 -----------------MASTWSLSKGLAAVVVTSAAAFG----------
MAB_2500|M.abscessus_ATCC_1997 -------------------------MDVAKLFVAGVIVAG----------
MSMEG_3441|M.smegmatis_MC2_155 ---------------------------MAPLAIAGLSVVG----------
MAV_3468|M.avium_104 TLTARTPDGSAPSREALAQAQQIISARVNGLGVSGSEVVVDGDNLIITVP
TH_3554|M.thermoresistible__bu -----------------------VAADAAAPTAAAAAVPAD---------
MLBr_02395|M.leprae_Br4923 --------------------------MTDQPPPSGSNPTP----------
Mvan_0309|M.vanbaalenii_PYR-1 ---------------------------------ALLGGAALAAATQAGAQ
Mflv_0374|M.gilvum_PYR-GCK ---------------------------------ALLSCAALAAATHAGAQ
Mb1891|M.bovis_AF2122/97 ---------------------------------ASLVTVAVPATANADPE
Rv1860|M.tuberculosis_H37Rv ---------------------------------ASLVTVAVPATANADPE
MMAR_4294|M.marinum_M ---------------------------------LCPGAAADPAAPQPNPN
MUL_1004|M.ulcerans_Agy99 ---------------------------------LCPAAAADPAAPQPNPN
MAB_2500|M.abscessus_ATCC_1997 ------------------------------------AALSLSAPAG--AD
MSMEG_3441|M.smegmatis_MC2_155 ------------------------------------LVMAAPAAADPVPD
MAV_3468|M.avium_104 GNDGNEARNLGQTARLYIRPVLNSMPAQSGEPKPAPRQPAQPAPGQPAPG
TH_3554|M.thermoresistible__bu -------------------------------PEGSSTFRALAWSQEEGVD
MLBr_02395|M.leprae_Br4923 -------------------------------------APPPPGSSGGYEP
. . .
Mvan_0309|M.vanbaalenii_PYR-1 PA-PVDPALPPAPPVVAAPA-----------PGAPVPG-VPAPGSHSVTV
Mflv_0374|M.gilvum_PYR-GCK PAVPFDP--PPPPPAAAPAQ-----------PQTPVFQYIPIAEGAAPGS
Mb1891|M.bovis_AF2122/97 PAPPVPTTAASPPSTAAAPP-----------APATPVAPPPPAAANTPNA
Rv1860|M.tuberculosis_H37Rv PAPPVPTTAASPPSTAAAPP-----------APATPVAPPPPAAANTPNA
MMAR_4294|M.marinum_M PQLPGLPALAQLSPIIQQAAGNPEQATQLLMAAAQAFAHNPAAPTESRNV
MUL_1004|M.ulcerans_Agy99 PQLPGLPALAQLSPIIQQAAGNPEQATQLLMAAAQAFAHNPAAPTESRNV
MAB_2500|M.abscessus_ATCC_1997 PAEPGPGPSPAPSAPQAAAP---------------------GTEALGPPP
MSMEG_3441|M.smegmatis_MC2_155 PAPPGP-AVAAPGQPIVEPA---------------------EGSALPPAP
MAV_3468|M.avium_104 QPAPGQPAPGQPAPGQPAPGQPAPAPAQPGAAPAQPRPYPQDPPPSPSPA
TH_3554|M.thermoresistible__bu DVVPFTGDGAYPDGPFTEGGYTDGPFTGQARPEVQWVPEQPVEESGAWSR
MLBr_02395|M.leprae_Br4923 SFAPSELGSAYPPPTAPPVGG--------SYPPPPPPGGSYPPPPPPGGS
*
Mvan_0309|M.vanbaalenii_PYR-1 TPLDAGSIPPPAPPPVGAP--VIPAVPNAN------------------FG
Mflv_0374|M.gilvum_PYR-GCK PAAPAGPVAPPAPPPAGAP--FIPPVPNAN------------------FG
Mb1891|M.bovis_AF2122/97 QPGDPNAAPPPADPNAPPPPVIAPNAPQPVRIDNPVGGFSFALPAGWVES
Rv1860|M.tuberculosis_H37Rv QPGDPNAAPPPADPNAPPPPVIAPNAPQPVRIDNPVGGFSFALPAGWVES
MMAR_4294|M.marinum_M ASSVNQFVQEPVNPAPGSPP-LGVPAPAAAPVEVAPPASAPVPHVPAPGA
MUL_1004|M.ulcerans_Agy99 ASSVNQFVQEPVNPAPGSPP-LGVPAPAAAPVEVAPPASAPVPHVPAPGA
MAB_2500|M.abscessus_ATCC_1997 PPALQPSVPEVTNPTYGSG------------------------------S
MSMEG_3441|M.smegmatis_MC2_155 PPVGPPPVPEMANPMYGSGQ-----------------------------S
MAV_3468|M.avium_104 PAPAPAPGPAPAPAPAPAPGEAPPGEQPAPPDPRKDLAERIAEEKKWRQS
TH_3554|M.thermoresistible__bu LPVALFSVAGVAVLLALGGVAYGLTSVSEDEPDPPVTEXXX-----QVLF
MLBr_02395|M.leprae_Br4923 YPPPPPSTGAYAPPPPGPAIRSLPKEAYTFWVTRVLAYVIDNIPATVLLG
. .
Mvan_0309|M.vanbaalenii_PYR-1 NTGQLDFLRELWNMRNSA-----EFFQSVGP----------GSLDPATWQ
Mflv_0374|M.gilvum_PYR-GCK NTGQFDFLRDLWNMRNSP-----EFMQSVGP----------GQMDPSTWV
Mb1891|M.bovis_AF2122/97 DAAHLDYGSALLSKTTGD-----PPFPGQPPPVANDTRIVLGRLDQKLYA
Rv1860|M.tuberculosis_H37Rv DAAHFDYGSALLSKTTGD-----PPFPGQPPPVANDTRIVLGRLDQKLYA
MMAR_4294|M.marinum_M EPGTLAHLPAGIDPAHAAGPAPVAAPAGAPPASAPAPAAAAPASAPGTAP
MUL_1004|M.ulcerans_Agy99 EPGTLAHLPAGIDPAHAAGPAPVAAPAGAPPASAPAPAAAAPASAPGTAP
MAB_2500|M.abscessus_ATCC_1997 G-GPLGTIRDLWHQAHD--GPLDTPEGVAGRP---------ANAGPAPQL
MSMEG_3441|M.smegmatis_MC2_155 GSGPLGSLRDLWHQARDPGGMQLAPTGGVAPP---------PGAGAPPPL
MAV_3468|M.avium_104 TRQGIQFLALQFQATRCDKDDILAGNDDPAQPLITCSTDHKVAYLLGPSI
TH_3554|M.thermoresistible__bu AAGVVAVLVALIAAIVTLRDGDTPAPASTTEPTEPTTTEPAGTVVTEAPP
MLBr_02395|M.leprae_Br4923 IGMLIQTLTKQEACVTDITQYNVNQYCATQPTGIGMLAFWFAWLMATAYL
.
Mvan_0309|M.vanbaalenii_PYR-1 PPTPYGTPPPP---------------------------------------
Mflv_0374|M.gilvum_PYR-GCK PPTPYGDPAAA---------------------------------------
Mb1891|M.bovis_AF2122/97 SAEATDSKAAARLGSDMGEFYMPYPGTRINQETVSLDANGVSGSASYYEV
Rv1860|M.tuberculosis_H37Rv SAEATDSKAAARLGSDMGEFYMPYPGTRINQETVSLDANGVSGSASYYEV
MMAR_4294|M.marinum_M APAAAPGPAPAAPAPAPAAAAPAPAPAPAAPPAAPVAA----PAPVPAPA
MUL_1004|M.ulcerans_Agy99 APAAAPGPAPAAPAPAPAAAAPAPAPAPAAPPAAPVAAPVAAPAPVPAPA
MAB_2500|M.abscessus_ATCC_1997 PPGYISTNAPE---------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 PPGYVSINAPG---------------------------------------
MAV_3468|M.avium_104 ISGDQIKDASASQNQRGIGFVVDLQFKPAAANTWADFTAAHIGTQTAFTL
TH_3554|M.thermoresistible__bu PAEPAAPQPPR---------------------------------------
MLBr_02395|M.leprae_Br4923 VWNYGYRQGATG--------------------------------------
.
Mvan_0309|M.vanbaalenii_PYR-1 -------------------PAA----APGSPPPP----------------
Mflv_0374|M.gilvum_PYR-GCK -------------------PAPP---AAGSPPVP----------------
Mb1891|M.bovis_AF2122/97 KFSDPSKPNGQIWTGVIGSPAAN---APDAGPPQRWFVVWLGTANNPVDK
Rv1860|M.tuberculosis_H37Rv KFSDPSKPNGQIWTGVIGSPAAN---APDAGPPQRWFVVWLGTANNPVDK
MMAR_4294|M.marinum_M PAAAPAPEAAAPAPAPAPAPAAAPGFGPDAPPTQDFMYPSIGTNCLADGS
MUL_1004|M.ulcerans_Agy99 PAAAPAPEAAAPAPAPAPAPAAAPGFGPDAPPTQDFMYPSIGTNCLADGS
MAB_2500|M.abscessus_ATCC_1997 ------------------SSNPGRIRDPYAAPEPS---------------
MSMEG_3441|M.smegmatis_MC2_155 ------------------SETP-VTEDP--AGNAG---------------
MAV_3468|M.avium_104 DSQVVSAPMIQEAIPGGRTQISG-GDPPFTAATAKQLANVLKYGSLPLSF
TH_3554|M.thermoresistible__bu -------------TVYETVPQTQAPPPPAEAPPPAQ--------------
MLBr_02395|M.leprae_Br4923 -------------SSIGKTVMKFKVISEATGQPIGFG-------------
Mvan_0309|M.vanbaalenii_PYR-1 ------ASAPPPVWPPVPVP-------------AQVP-------------
Mflv_0374|M.gilvum_PYR-GCK ------ASAPPPIWPPVPVP-------------APVP-------------
Mb1891|M.bovis_AF2122/97 GAAKALAESIRPLVAPPPAP-------------APAPAEPAPAPAPAGEV
Rv1860|M.tuberculosis_H37Rv GAAKALAESIRPLVAPPPAP-------------APAPAEPAPAPAPAGEV
MMAR_4294|M.marinum_M NIIATALSVAGPATIPTPGPGPGQTAYVFTAVGTPGPAEVQRLPLNVTWV
MUL_1004|M.ulcerans_Agy99 NIIATALSVAGPATIPTPGPGPGQTAYVFTAVGTPGPAEVQRLPLNVTWV
MAB_2500|M.abscessus_ATCC_1997 ------GPPLPPGYHSLNGP--------------PPPGYEPTGPAPAAAT
MSMEG_3441|M.smegmatis_MC2_155 ------GPPLPPGYYPLDGP--------------PPPGYEYNSPVP----
MAV_3468|M.avium_104 QSSEAQTVSATLGLTSLRAGLIAGAIGLLLVLLYSLLYYRVLGLLTALSL
TH_3554|M.thermoresistible__bu --EPPPAEEPPPAEEPPPATE------------EPPPTTTRPRWLPTLPR
MLBr_02395|M.leprae_Br4923 ------MSVVRQLAHFVDAVICCIG--------FLFPLWDSKRQTLADKI
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mb1891|M.bovis_AF2122/97 APTPTTPTPQRTLPA-----------------------------------
Rv1860|M.tuberculosis_H37Rv APTPTTPTPQRTLPA-----------------------------------
MMAR_4294|M.marinum_M NLTTGKSGSVTLKPRSDINPEGPTTLTGIADTGSGSIMSTIFGQVTTKER
MUL_1004|M.ulcerans_Agy99 NLTTGKSGSVTLKPRSDINPEGPTTLTGIADTGSGSIMSTIFGQVTTKER
MAB_2500|M.abscessus_ATCC_1997 P-------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3468|M.avium_104 AASGAMVFAILILLGRYINYTLDLAGIAGLIIGIGTTADSFVVFFERIKD
TH_3554|M.thermoresistible__bu PTLPTLPTIPGLPAPPAPPAEAP---------------------------
MLBr_02395|M.leprae_Br4923 MTTVCLPI------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mb1891|M.bovis_AF2122/97 --------------------------------------------------
Rv1860|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4294|M.marinum_M QCQFMPTIGSTVVP------------------------------------
MUL_1004|M.ulcerans_Agy99 QCQFMPTIGSTVVP------------------------------------
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3468|M.avium_104 EIREGRTFRSAVPRGWTRARKTIVSGNAVTFLAAAVLYFLAIGQVKGFAF
TH_3554|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0374|M.gilvum_PYR-GCK --------------------------------------------------
Mb1891|M.bovis_AF2122/97 --------------------------------------------------
Rv1860|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4294|M.marinum_M --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MAB_2500|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3441|M.smegmatis_MC2_155 --------------------------------------------------
MAV_3468|M.avium_104 TLGLTTILDLVVVFLVTWPLVYLASKSPTLAKPAYNGLGAVQQVARERRA
TH_3554|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mvan_0309|M.vanbaalenii_PYR-1 ---------
Mflv_0374|M.gilvum_PYR-GCK ---------
Mb1891|M.bovis_AF2122/97 ---------
Rv1860|M.tuberculosis_H37Rv ---------
MMAR_4294|M.marinum_M ---------
MUL_1004|M.ulcerans_Agy99 ---------
MAB_2500|M.abscessus_ATCC_1997 ---------
MSMEG_3441|M.smegmatis_MC2_155 ---------
MAV_3468|M.avium_104 AAHVSTGQG
TH_3554|M.thermoresistible__bu ---------
MLBr_02395|M.leprae_Br4923 ---------